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  1. Book: Lousy sex

    Callahan, Gerald N

    creating self in an infectious world

    2013  

    Abstract: In Lousy Sex Gerald Callahan explores the science of self, illustrating the immune system's role ... in our bodies are bacteria--we are in many respects more non-self than self. In Lousy Sex, Callahan considers ... who we are, Callahan uses autobiographical episodes to illustrate his scientific points. Through stories ...

    Author's details Gerald N. Callahan
    Abstract "In Lousy Sex Gerald Callahan explores the science of self, illustrating the immune system's role in forming individual identity. Blending the scientific essay with deeply personal narratives, these poignant and enlightening stories use microbiology and immunology to explore a new way to answer the question, who am I? "Self" has many definitions. Science has demonstrated that 90 percent of the cells in our bodies are bacteria--we are in many respects more non-self than self. In Lousy Sex, Callahan considers this microbio-neuro perspective on human identity together with the soulful, social perception of self, drawing on both art and science to fully illuminate this relationship. In his stories about where we came from and who we are, Callahan uses autobiographical episodes to illustrate his scientific points. Through stories about the sex lives of wood lice, the biological advantages of eating dirt, the question of immortality, the relationship between syphilis and the musical genius of Beethoven, and more, this book creates another way, a chimeric way, of seeing ourselves. The general reader with an interest in science will find Lousy Sex fascinating"--Provided by publisher.
    MeSH term(s) Self Concept ; Immune System ; Identification (Psychology) ; Individuality
    Language English
    Size xiv, 175 pages :, illustrations ;, 23 cm
    Document type Book
    ISBN 9781607322320 ; 1607322323 ; 9781607322337 ; 1607322331
    Database Catalogue of the US National Library of Medicine (NLM)

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  2. Article: First self.

    Callahan, Gerald N

    Emerging infectious diseases

    2005  Volume 11, Issue 2, Page(s) 333–338

    MeSH term(s) Anecdotes as Topic ; Ego ; Female ; Humans ; Male
    Language English
    Publishing date 2005-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1380686-5
    ISSN 1080-6040
    ISSN 1080-6040
    DOI 10.3201/eid1102.ad1102
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Effect of Commonly Used Local Anesthetic on Bacterial Growth.

    Callahan, Zachary M / Roberts, Amity L / Christopher, Adrienne N / Gadomski, Stephen P / Kuchta, Kristine M / Costanzo, Caitlyn M / Phillips, Benjamin R / Isenberg, Gerald A / Goldstein, Scott D

    The Journal of surgical research

    2022  Volume 274, Page(s) 16–22

    Abstract: Introduction: Liposomal bupivacaine (LB) has emerged as a superior form of local anesthetic across numerous surgical subspecialties. The purpose of this study is to evaluate the ex-vivo antimicrobial effects of LB in comparison with traditional local ... ...

    Abstract Introduction: Liposomal bupivacaine (LB) has emerged as a superior form of local anesthetic across numerous surgical subspecialties. The purpose of this study is to evaluate the ex-vivo antimicrobial effects of LB in comparison with traditional local anesthetics.
    Methods: A standardized inoculum of bacteria commonly associated with surgical site infection was inoculated into a suspension of 1% lidocaine, 0.25% bupivacaine, Exparel (proprietary liposomally packaged 1.3% bupivacaine), and normal saline as a growth control.
    Results: In all five bacteria tested, the medium inoculated with traditional local anesthetics reduced growth to a greater degree than LB-inoculated plates. Both conventional local anesthetics reduced the growth of all bacteria when compared with the control with the exception of methicillin-susceptible Staphylococcus aureus growth in bupivacaine. LB-inoculated plates had equivalent growth to the control in all plates with the exception of Escherichia coli plates which demonstrated superior growth.
    Conclusions: The results of this simple ex-vivo model suggest that the liposomal packaging of bupivacaine may decrease this local anesthetic's innate antibacterial properties.
    MeSH term(s) Anesthesia, Local ; Anesthetics, Local/pharmacology ; Bupivacaine/pharmacology ; Escherichia coli ; Humans ; Lidocaine/pharmacology ; Pain, Postoperative ; Staphylococcus aureus
    Chemical Substances Anesthetics, Local ; Lidocaine (98PI200987) ; Bupivacaine (Y8335394RO)
    Language English
    Publishing date 2022-02-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80170-7
    ISSN 1095-8673 ; 0022-4804
    ISSN (online) 1095-8673
    ISSN 0022-4804
    DOI 10.1016/j.jss.2021.12.040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Does Standard Physical Therapy Increase Quadriceps Strength in Chronically Ventilated Patients? A Pilot Study.

    Supinski, Gerald S / Valentine, Emily N / Netzel, Paul F / Schroder, Elizabeth A / Wang, Lin / Callahan, Leigh Ann

    Critical care medicine

    2020  Volume 48, Issue 11, Page(s) 1595–1603

    Abstract: Objectives: Physical therapy is standard care for mechanically ventilated patients, but there is no evidence, using nonvolitional, objective measurements, that physical therapy increases muscle strength in this population. The present study tested the ... ...

    Abstract Objectives: Physical therapy is standard care for mechanically ventilated patients, but there is no evidence, using nonvolitional, objective measurements, that physical therapy increases muscle strength in this population. The present study tested the hypothesis that 2 weeks of standard, conventional physical therapy provided at a ventilator weaning facility would increase quadriceps strength in mechanically ventilated patients.
    Design: Prospective observational study.
    Setting: Ventilator weaning unit.
    Patients: Patients who were transferred from an acute care hospital because of failure to wean from mechanical ventilation and who were receiving physical therapy as prescribed by facility staff.
    Interventions: None.
    Measurements and main results: We employed a novel, nonvolitional objective technique, quadriceps twitch force generation in response to femoral nerve magnetic stimulation, to assess leg strength before and after 2 weeks of conventional physical therapy. The duration and specific exercises provided to patients were also recorded. In a subset of patients, we measured muscle activation intensity using wireless electromyogram recordings. Indices of respiratory function (maximum inspiratory pressure generation and the rapid shallow breathing index) were also assessed. Patients' responses to 2 weeks of physical therapy were poor; on average, quadriceps twitch fell by -1.02 ± 0.71 Newtons. Neither physical therapy duration nor specific forms of exercise were identified to positively impact quadriceps twitch. Electromyogram recordings indicated that during training, muscle activation was poor. Consequently, therapists spent substantial time performing exercises that elicited little muscle activation. Physical therapy did not improve respiratory function.
    Conclusions: Standard physical therapy delivered in a ventilator weaning facility failed to improve quadriceps leg strength in a majority of mechanically ventilated patients. The fact that mechanically ventilated patients fail to achieve high levels of muscle activation during physical therapy provides a potential explanation as to why physical therapy may often be ineffective. We speculate that use of novel methods which increase muscle activation during exercise may improve responses of mechanically ventilated patients to physical therapy.
    MeSH term(s) Electromyography ; Female ; Humans ; Male ; Middle Aged ; Muscle Strength ; Physical Therapy Modalities ; Pilot Projects ; Prospective Studies ; Quadriceps Muscle ; Respiration, Artificial/adverse effects ; Treatment Outcome ; Ventilator Weaning/adverse effects ; Ventilator Weaning/methods
    Language English
    Publishing date 2020-08-21
    Publishing country United States
    Document type Journal Article ; Observational Study ; Research Support, N.I.H., Extramural
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000004544
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Eating dirt.

    Callahan, Gerald N

    Emerging infectious diseases

    2003  Volume 9, Issue 8, Page(s) 1016–1021

    MeSH term(s) Adult ; Animals ; Child, Preschool ; Cultural Diversity ; Female ; Humans ; Pica/microbiology ; Pica/parasitology ; Pica/psychology ; Pregnancy ; Religion and Medicine
    Language English
    Publishing date 2003-09-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1380686-5
    ISSN 1080-6040
    ISSN 1080-6040
    DOI 10.3201/eid0908.ad0908
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Madness.

    Callahan, Gerald N

    Emerging infectious diseases

    2002  Volume 8, Issue 9, Page(s) 998–1002

    MeSH term(s) Animals ; Ants/parasitology ; Ants/physiology ; Borna disease virus/physiology ; Cats ; Depression/etiology ; Depression/physiopathology ; Dicrocoelium/physiology ; Female ; Humans ; Male ; Mental Disorders/etiology ; Mental Disorders/microbiology ; Mental Disorders/physiopathology ; Mental Disorders/virology ; Neurosyphilis/complications ; Paintings ; Phthiraptera/parasitology ; Phthiraptera/physiology ; Rats ; Toxoplasma/physiology ; Wolbachia/physiology
    Language English
    Publishing date 2002-09-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1380686-5
    ISSN 1080-6040
    ISSN 1080-6040
    DOI 10.3201/eid0809.ad0809
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Basic veterinary immunology

    Callahan, Gerald N / Yates, Robin M

    2014  

    Abstract: Designed to fill the current gap in resources for teaching veterinary immunology, Basic Veterinary Immunology offers a solid background in the essentials of immunology within the context of veterinary medicine. The book combines a clinical framework ... ...

    Author's details Gerald N. Callahan and Robin M. Yates ; Veterinary clinical laboratory immunology chapter by Amy Warren
    Abstract "Designed to fill the current gap in resources for teaching veterinary immunology, Basic Veterinary Immunology offers a solid background in the essentials of immunology within the context of veterinary medicine. The book combines a clinical framework complete with real-world examples to integrate the theory and practice of veterinary medicine. Each chapter begins with a clinically relevant veterinary issue and then presents one aspect of basic immunology in the context of that issue. All chapters include learning objectives and a clinical correlation follow-up section that includes student considerations and a review of the possible explanations for the clinical presentation. Illustrated with 250 full-color images and figures that will also be available as PowerPoint teaching aids, Basic Veterinary Immunology and related materials will be made available online to students, faculty, and clinical veterinarians in partnership with the Veterinary Information Network. Basic Veterinary Immunology will provide students with a good working knowledge of veterinary immunology that will serve them both in the completion of their curricula and in professional practice"--Provided by publisher.
    MeSH term(s) Animal Diseases/immunology ; Animal Population Groups/immunology ; Immune System Phenomena ; Veterinary Medicine/methods ; Immune System Diseases/veterinary
    Language English
    Size x, 337 pages :, illustrations.
    Document type Book
    Note Includes index.
    ISBN 9781607322184 ; 1607322188
    Database Catalogue of the US National Library of Medicine (NLM)

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  8. Book: Basic veterinary immunology

    Callahan, Gerald N / Yates, Robin M

    2014  

    Abstract: Designed to fill the current gap in resources for teaching veterinary immunology, Basic Veterinary Immunology offers a solid background in the essentials of immunology within the context of veterinary medicine. The book combines a clinical framework ... ...

    Author's details Gerald N. Callahan and Robin M. Yates; Veterinary clinical laboratory immunology chapter by Amy Warren
    Abstract "Designed to fill the current gap in resources for teaching veterinary immunology, Basic Veterinary Immunology offers a solid background in the essentials of immunology within the context of veterinary medicine. The book combines a clinical framework complete with real-world examples to integrate the theory and practice of veterinary medicine. Each chapter begins with a clinically relevant veterinary issue and then presents one aspect of basic immunology in the context of that issue. All chapters include learning objectives and a clinical correlation follow-up section that includes student considerations and a review of the possible explanations for the clinical presentation. Illustrated with 250 full-color images and figures that will also be available as PowerPoint teaching aids, Basic Veterinary Immunology and related materials will be made available online to students, faculty, and clinical veterinarians in partnership with the Veterinary Information Network. Basic Veterinary Immunology will provide students with a good working knowledge of veterinary immunology that will serve them both in the completion of their curricula and in professional practice"--Provided by publisher
    MeSH term(s) Animal Diseases/immunology ; Animal Population Groups/immunology ; Immune System Diseases/veterinary ; Immune System Phenomena ; Veterinary Medicine/methods
    Keywords Veterinary immunology
    Language English
    Size X, 337 S., Ill.
    Publisher University Press of Colorado
    Publishing place Boulder
    Document type Book
    Note Includes bibliographical references and index
    ISBN 9781607322184 ; 1607322188
    Database Friedrich Loeffler-Institute, Federal Research Institute for Animal Health

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  9. Article ; Online: Eating Dirt

    Gerald N. Callahan

    Emerging Infectious Diseases, Vol 9, Iss 8, Pp 1016-

    2003  Volume 1021

    Abstract: Please This earth is blessed Do not play in it Sign on the wall of El Santuario de Chimayo, New ... ...

    Abstract Please This earth is blessed Do not play in it Sign on the wall of El Santuario de Chimayo, New Mexico
    Keywords United States ; Medicine ; R ; Infectious and parasitic diseases ; RC109-216
    Language English
    Publishing date 2003-08-01T00:00:00Z
    Publisher Centers for Disease Control and Prevention
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Book: Faith, madness, and spontaneous human combustion

    Callahan, Gerald N

    what immunology can teach us about self-perception

    2002  

    Author's details Gerald N. Callahan
    MeSH term(s) Immune System ; Philosophy
    Language English
    Size xvii, 235 p. ;, 22 cm.
    Edition 1st ed.
    Publisher Thomas Dunne Books/St. Martin's Press
    Publishing place New York
    Document type Book
    ISBN 9780312268077 ; 0312268076
    Database Catalogue of the US National Library of Medicine (NLM)

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