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Article ; Online: A critical review on graphene oxide membrane for industrial wastewater treatment.

An, Ye-Chen / Gao, Xiao-Xu / Jiang, Wen-Li / Han, Jing-Long / Ye, Yuan / Chen, Tian-Ming / Ren, Rui-Yun / Zhang, Jia-Hui / Liang, Bin / Li, Zhi-Ling / Wang, Ai-Jie / Ren, Nan-Qi

Environmental research

2023 Volume 223, Page(s) 115409

Abstract: An important way to promote the environmental industry's goal of carbon reduction is to promote the recycling of resources. Membrane separation technology has unique advantages in resource recovery and advanced treatment of industrial wastewater. However, ...

Abstract	An important way to promote the environmental industry's goal of carbon reduction is to promote the recycling of resources. Membrane separation technology has unique advantages in resource recovery and advanced treatment of industrial wastewater. However, the great promise of traditional organic membrane is hampered by challenges associated with organic solvent tolerance, lack of oxidation resistance, and serious membrane fouling control. Moreover, the high concentrations of organic matter and inorganic salts in the membrane filtration concentrate also hinder the wider application of the membrane separation technology. The emerging cost-effective graphene oxide (GO)-based membrane with excellent resistance to organic solvents and oxidants, more hydrophilicity, lower membrane fouling, better separation performance has been expected to contribute more in industrial wastewater treatment. Herein, we provide comprehensive insights into the preparation and characteristic of GO membranes, as well as current research status and problems related to its future application in industrial wastewater treatment. Finally, concluding remarks and future perspectives have been deduced and recommended for the GO membrane separation technology application for industrial wastewater treatment, which leads to realizing sustainable wastewater recycling and a nearly "zero discharge" water treatment process.
MeSH term(s)	Wastewater ; Membranes, Artificial ; Graphite ; Water Purification
Chemical Substances	Wastewater ; graphene oxide ; Membranes, Artificial ; Graphite (7782-42-5)
Language	English
Publishing date	2023-02-04
Publishing country	Netherlands
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2023.115409
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Article ; Online: Four dodecanoic acid derivatives from the cold-seep-derived fungus

Li, Chang-Peng / Song, Yin-Ping / Liang, Xiao-Rui / Ji, Nai-Yun

Natural product research

2023 , Page(s) 1–6

Abstract: Two new compounds, cladospolides I ( ...

Abstract	Two new compounds, cladospolides I (
Language	English
Publishing date	2023-05-17
Publishing country	England
Document type	Journal Article
ZDB-ID	2185747-7
ISSN	1478-6427 ; 1478-6419
ISSN (online)	1478-6427
ISSN	1478-6419
DOI	10.1080/14786419.2023.2214291
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Article ; Online: A critical review on graphene oxide membrane for industrial wastewater treatment

An, Ye-Chen / Gao, Xiao-Xu / Jiang, Wen-Li / Han, Jing-Long / Ye, Yuan / Chen, Tian-Ming / Ren, Rui-Yun / Zhang, Jia-Hui / Liang, Bin / Li, Zhi-Ling / Wang, Ai-Jie / Ren, Nan-Qi

Environmental Research. 2023 Feb. 04, p.115409-

2023 , Page(s) 115409–

Abstract	An important way to promote the environmental industry's goal of carbon reduction is to promote the recycling of resources. Membrane separation technology has unique advantages in resource recovery and advanced treatment of industrial wastewater. However, the great promise of traditional organic membrane is hampered by challenges associated with organic solvent tolerance, lack of oxidation resistance, and serious membrane fouling control. Moreover, the high concentrations of organic matter and inorganic salts in the membrane filtration concentrate also hinder the wider application of the membrane separation technology. The emerging cost-effective graphene oxide (GO)-based membrane with excellent resistance to organic solvents and oxidants, more hydrophilicity, lower membrane fouling, better separation performance has been expected to contribute more in industrial wastewater treatment. Herein, we provide comprehensive insights into the preparation and characteristic of GO membranes, as well as current research status and problems related to its future application in industrial wastewater treatment. Finally, concluding remarks and future perspectives have been deduced and recommended for the GO membrane separation technology application for industrial wastewater treatment, which leads to realizing sustainable wastewater recycling and a nearly “zero discharge” water treatment process.
Keywords	carbon ; cost effectiveness ; graphene oxide ; hydrophilicity ; industrial wastewater ; industrial wastewater treatment ; industry ; microfiltration ; organic matter ; oxidation ; research ; solvents ; Graphene oxide membrane ; Advanced wastewater treatment ; Membrane technology ; Inorganic cross-linking ; Membrane fouling control
Language	English
Dates of publication	2023-0204
Publishing place	Elsevier Inc.
Document type	Article ; Online
Note	Pre-press version
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2023.115409
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Article: Differences in pulmonary nodular consolidation and pulmonary cavity among drug-sensitive, rifampicin-resistant and multi-drug resistant tuberculosis patients: the Guangzhou computerized tomography study.

Fang, Wei-Jun / Tang, Sheng-Nan / Liang, Rui-Yun / Zheng, Qiu-Ting / Yao, Dian-Qi / Hu, Jin-Xing / Song, Min / Zheng, Guang-Ping / Rosenthal, Alex / Tartakovsky, Michael / Lu, Pu-Xuan / Wáng, Yì Xiáng J

Quantitative imaging in medicine and surgery

2023 Volume 14, Issue 1, Page(s) 1010–1021

Abstract: Background: Pulmonary nodular consolidation (PN) and pulmonary cavity (PC) may represent the two most promising imaging signs in differentiating multidrug-resistant (MDR)-pulmonary tuberculosis (PTB) from drug-sensitive (DS)-PTB. However, there have ... ...

Abstract	Background: Pulmonary nodular consolidation (PN) and pulmonary cavity (PC) may represent the two most promising imaging signs in differentiating multidrug-resistant (MDR)-pulmonary tuberculosis (PTB) from drug-sensitive (DS)-PTB. However, there have been concerns that literature described radiological feature differences between DS-PTB and MDR-PTB were confounded by that MDR-PTB cases tend to have a longer history. This study seeks to further clarify this point. Methods: All cases were from the Guangzhou Chest Hospital, Guangzhou, China. We retrieved data of consecutive new MDR cases [n=46, inclusive of rifampicin-resistant (RR) cases] treated during the period of July 2020 and December 2021, and according to the electronic case archiving system records, the main PTB-related symptoms/signs history was ≤3 months till the first computed tomography (CT) scan in Guangzhou Chest Hospital was taken. To pair the MDR-PTB cases with assumed equal disease history length, we additionally retrieved data of 46 cases of DS-PTB patients. Twenty-two of the DS patients and 30 of the MDR patients were from rural communities. The first CT in Guangzhou Chest Hospital was analysed in this study. When the CT was taken, most cases had anti-TB drug treatment for less than 2 weeks, and none had been treated for more than 3 weeks. Results: Apparent CT signs associated with chronicity were noted in 10 cases in the DS group (10/46) and 9 cases in the MDR group (10/46). Thus, the overall disease history would have been longer than the assumed <3 months. Still, the history length difference between DS patients and MDR patients in the current study might not be substantial. The lung volume involvement was 11.3%±8.3% for DS cases and 8.4%±6.6% for MDR cases (P=0.022). There was no statistical difference between DS cases and MDR cases both in PN prevalence and in PC prevalence. For positive cases, MDR cases had more PN number (mean of positive cases: 2.63 Conclusions: A combination of PN and PC features allows statistical separation of DS and MDR cases.
Language	English
Publishing date	2023-11-20
Publishing country	China
Document type	Journal Article
ZDB-ID	2653586-5
ISSN	2223-4306 ; 2223-4292
ISSN (online)	2223-4306
ISSN	2223-4292
DOI	10.21037/qims-23-694
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Article ; Online: Norbornene Derivatives-Controlled Palladium-Catalyzed Divergent Synthesis of Dibenzo[

Zhou, Liwei / Jing, Pengyang / Li, Zhiwei / Liu, Rui / Chen, Jiannan / Deng, Guobo / Liang, Yun / Yang, Yuan

Organic letters

2024 Volume 26, Issue 3, Page(s) 676–680

Abstract: A palladium-catalyzed divergent cascade decarboxylative annulation of aryl iodides and α-oxocarboxylic acids using norbornene (NBE) derivatives as a controlled switch is reported. When NBE is used as a mediator, fluorenones are synthesized with moderate ... ...

Abstract	A palladium-catalyzed divergent cascade decarboxylative annulation of aryl iodides and α-oxocarboxylic acids using norbornene (NBE) derivatives as a controlled switch is reported. When NBE is used as a mediator, fluorenones are synthesized with moderate to excellent yields via a Catellani reaction that involves sequential
Language	English
Publishing date	2024-01-18
Publishing country	United States
Document type	Journal Article
ISSN	1523-7052
ISSN (online)	1523-7052
DOI	10.1021/acs.orglett.3c04065
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Article ; Online: Endoplasmic Reticulum-Targeting Self-Assembly Nanosheets Promote Autophagy and Regulate Immunosuppressive Tumor Microenvironment for Efficient Photodynamic Immunotherapy.

Huang, Pei-Ying / Liang, Shi-Yu / Xiang, Yun / Li, Ming-Rui / Wang, Mei-Rong / Liu, Li-Han

Small (Weinheim an der Bergstrasse, Germany)

2024 , Page(s) e2311056

Abstract: The poor efficiency and low immunogenicity of photodynamic therapy (PDT), and the immunosuppressive tumor microenvironment (ITM) lead to tumor recurrence and metastasis. In this work, TCPP- ... ...

Abstract	The poor efficiency and low immunogenicity of photodynamic therapy (PDT), and the immunosuppressive tumor microenvironment (ITM) lead to tumor recurrence and metastasis. In this work, TCPP-T
Language	English
Publishing date	2024-02-20
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2168935-0
ISSN	1613-6829 ; 1613-6810
ISSN (online)	1613-6829
ISSN	1613-6810
DOI	10.1002/smll.202311056
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Article: A New Compound from the Endophytic Fungus Xylaria sp. from Sophora tonkinensis

Zheng, Na / Dong-Lan He / Jun Li / Quan Liu / Rui-Yun Yang / Yan Liang

Chemistry of natural compounds. 2018 May, v. 54, no. 3

2018

Abstract: A new compound, 6-heptanoyl-4-methoxy-2H-pyran-2-one (1), was isolated from the endophytic fungus Xylaria sp. GDG-102 from the leaf of Sophora tonkinensis. The structure of the new compound was elucidated on the basis of 1D and 2D NMR spectra. Compound 1 ...

Abstract	A new compound, 6-heptanoyl-4-methoxy-2H-pyran-2-one (1), was isolated from the endophytic fungus Xylaria sp. GDG-102 from the leaf of Sophora tonkinensis. The structure of the new compound was elucidated on the basis of 1D and 2D NMR spectra. Compound 1 showed antimicrobial activity against E. coli and S. aureus with MIC values 50 μg/mL.
Keywords	antimicrobial properties ; chemistry ; endophytes ; Escherichia coli ; fungi ; leaves ; minimum inhibitory concentration ; nuclear magnetic resonance spectroscopy ; Sophora tonkinensis ; Xylaria
Language	English
Dates of publication	2018-05
Size	p. 447-449.
Publishing place	Springer US
Document type	Article
ZDB-ID	213866-9
ISSN	0009-3130
ISSN	0009-3130
DOI	10.1007/s10600-018-2376-1
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Zs.A 3107: Show issues

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Article: Safety, Tolerability and Pharmacokinetics of Single-Dose Oral SYHA1402 in Healthy Chinese Subjects.

Liang, Beibei / Wang, Jin / Zhang, Guanxuanzi / Wang, Rui / Cai, Yun

Neurology and therapy

2023 Volume 12, Issue 3, Page(s) 947–959

Abstract: Introduction: To assess the safety, tolerability and pharmacokinetics of a single dose of SYHA1402 in healthy Chinese subjects.: Methods: This was a randomized, double-blind, placebo-controlled, single-ascending dose study in healthy subjects. ... ...

Abstract	Introduction: To assess the safety, tolerability and pharmacokinetics of a single dose of SYHA1402 in healthy Chinese subjects. Methods: This was a randomized, double-blind, placebo-controlled, single-ascending dose study in healthy subjects. Subjects received a single dose of SYHA1402 25 mg, 50 mg, 100 mg, 200 mg, 400 mg or 800 mg, or matching placebo. Safety and tolerability were assessed throughout the study. The pharmacokinetic (PK) parameters of SYHA1402 were estimated using non-compartmental analysis. Results: In all, 54 subjects were enrolled and completed the study. Specifically, there were no deaths, serious adverse events or withdrawals from study due to adverse events. All treatment-emergent adverse events were mild. The most common drug-related adverse event was sinus bradycardia. The time to maximum concentration ranged from 1.13 to 2.25 h, and the terminal elimination half-life range was 1.51-4.70 h. SYHA1402 exhibited nonlinear PK parameters with less than dose-proportional increases in exposure after single oral doses of 25 to 800 mg. Conclusion: SYHA1402 administered as a single dose was well tolerated and safe over the dose range of 25-800 mg. More than 50% of the unchanged SYHA1402 was excreted in urine within the dose range of 25-100 mg. Trial registration: NCT03988413 ( https://www. Clinicaltrials: gov/ registration date: 17 June 2019).
Language	English
Publishing date	2023-04-24
Publishing country	New Zealand
Document type	Journal Article
ISSN	2193-8253
ISSN	2193-8253
DOI	10.1007/s40120-023-00480-x
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Article ; Online: Quantitative evaluation of passive muscle stiffness by shear wave elastography in healthy individuals of different ages.

Liu, Xiao / Yu, Hong-Kui / Sheng, Shu-Ya / Liang, Si-Min / Lu, Hao / Chen, Rui-Yun / Pan, Min / Wen, Zhi-Bo

European radiology

2020 Volume 31, Issue 5, Page(s) 3187–3194

Abstract: Objectives: To investigate age-related changes on passive muscle stiffness in healthy individuals and measure the shear modulus in different age groups.: Methods: Shear wave elastography (SWE) movies of gastrocnemius medialis (GM) were collected ... ...

Abstract	Objectives: To investigate age-related changes on passive muscle stiffness in healthy individuals and measure the shear modulus in different age groups. Methods: Shear wave elastography (SWE) movies of gastrocnemius medialis (GM) were collected during passive stretching induced by ankle rotation from plantarflexion (PF) to dorsiflexion (DF). A series of SWE images at ankle angles of PF 40°, PF 30°, PF 20°, PF 10°, 0°, DF 10°, DF 20°, and DF 30° were collected and shear moduli measured accordingly for analyses. Results: Eighty-six healthy volunteers (27 children, 31 middle-aged adults, and 28 older people) were recruited. No significant difference was observed in the shear modulus between the three groups at ankle angles of PF 40°, PF 30°, PF 20°, PF 10°, and 0° (p > 0.05). The difference in the shear modulus among the three groups became significant as DF increased. At ankle angles of DF 10°, DF 20°, and DF 30°, the shear modulus was the greatest in the older group, followed by the middle-aged group and then the children group (p = 0.007, 0.000, and 0.000, respectively). Conclusions: Passive muscle stiffness increases with age, and the difference between age groups was pronounced only after reaching a certain degree of stretching. Key points: • The influence of age on passive muscle stiffness becomes pronounced only after reaching a certain degree of stretching. • Age should be considered when evaluating passive muscle stiffness in muscular disorders.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Ankle ; Ankle Joint/diagnostic imaging ; Child ; Elasticity Imaging Techniques ; Humans ; Middle Aged ; Muscle, Skeletal/diagnostic imaging ; Range of Motion, Articular
Language	English
Publishing date	2020-10-14
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1085366-2
ISSN	1432-1084 ; 0938-7994 ; 1613-3749
ISSN (online)	1432-1084
ISSN	0938-7994 ; 1613-3749
DOI	10.1007/s00330-020-07367-7
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Article: Analysis of the influences of social isolation on cognition and the therapeutic potential of deep brain stimulation in a mouse model.

Hu, Yun-Yun / Ding, Xuan-Si / Yang, Gang / Liang, Xue-Song / Feng, Lei / Sun, Yan-Yun / Chen, Rui / Ma, Quan-Hong

Frontiers in psychiatry

2023 Volume 14, Page(s) 1186073

Abstract: Background: Social interaction is a fundamental human need. Social isolation (SI) can have negative effects on both emotional and cognitive function. However, it is currently unclear how age and the duration of SI affect emotion and recognition function. ...

Abstract	Background: Social interaction is a fundamental human need. Social isolation (SI) can have negative effects on both emotional and cognitive function. However, it is currently unclear how age and the duration of SI affect emotion and recognition function. In addition, there is no specific treatment for the effects of SI. Methods: The adolescence or adult mice were individually housed in cages for 1, 6 or 12 months and for 2 months to estabolish SI mouse model. We investigated the effects of SI on behavior in mice at different ages and under distinct durations of SI, and we explored the possible underlying mechanisms. Then we performed deep brain stimulation (DBS) to evaluate its influences on SI induced behavioral abnormalities. Results: We found that social recognition was affected in the short term, while social preference was damaged by extremely long periods of SI. In addition to affecting social memory, SI also affects emotion, short-term spatial ability and learning willingness in mice. Myelin was decreased significantly in the medial prefrontal cortex (mPFC) and dorsal hippocampus of socially isolated mice. Cellular activity in response to social stimulation in both areas was impaired by social isolation. By stimulating the mPFC using DBS, we found that DBS alleviated cellular activation disorders in the mPFC after long-term SI and improved social preference in mice. Conclusion: Our results suggest that the therapeutic potential of stimulating the mPFC with DBS in individuals with social preference deficits caused by long-term social isolation, as well as the effects of DBS on the cellular activity and density of OPCs.
Language	English
Publishing date	2023-06-20
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564218-2
ISSN	1664-0640
ISSN	1664-0640
DOI	10.3389/fpsyt.2023.1186073
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