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  1. Article ; Online: Moving between doing and being-Meanings of person-centredness as narrated by nursing home managers. A phenomenological hermeneutical study.

    Backman, Annica / Sjögren, Karin / Lövheim, Hugo / Edvardsson, David

    Nursing open

    2024  Volume 11, Issue 1, Page(s) e2073

    Abstract: Aim: This study aimed to illuminate meanings of person-centredness as narrated by nursing home managers in nursing homes rated as highly person-centred.: Design: A phenomenological hermeneutical approach was used.: Methods: Twelve nursing home ... ...

    Abstract Aim: This study aimed to illuminate meanings of person-centredness as narrated by nursing home managers in nursing homes rated as highly person-centred.
    Design: A phenomenological hermeneutical approach was used.
    Methods: Twelve nursing home managers in 11 highly person-centred nursing homes in 7 municipalities in Sweden were included in this interview study. The findings were interpreted, reflected and discussed through the lens of Ricoeur.
    Results: Meanings of person-centredness could be understand as moving between doing and being through knowing, sensing, sharing and giving for person-centredness. These aspects contributed via knowledge, understanding, interaction and action that involved doing for and being with older persons through these caring dimensions. By moving between doing for, being with and being part of the overall nursing home narrative, knowing, sensing, sharing and giving could support the persons' identity in different ways. This may also contribute to sense-making, preserving dignity and promoting self-esteem when aiming to provide a good life for older persons in nursing homes, within an ever-present ethical frame.
    No patient or public contribution: This study illuminated meanings of person-centredness as narrated by nursing home managers. No patient of public contribution was investigated.
    MeSH term(s) Humans ; Aged ; Aged, 80 and over ; Nursing Homes ; Skilled Nursing Facilities ; Knowledge ; Lens, Crystalline ; Lenses
    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2809556-X
    ISSN 2054-1058 ; 2054-1058
    ISSN (online) 2054-1058
    ISSN 2054-1058
    DOI 10.1002/nop2.2073
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Added Value of Remote Technology in Cardiac Rehabilitation on Physical Function, Anthropometrics, and Quality of Life: Cluster Randomized Controlled Trial.

    Lahtio, Heli / Heinonen, Ari / Paajanen, Teemu / Sjögren, Tuulikki

    Journal of medical Internet research

    2023  Volume 25, Page(s) e42455

    Abstract: Background: Cardiovascular diseases (CVDs) cause most deaths globally and can reduce quality of life (QoL) of rehabilitees with cardiac disease. The risk factors of CVDs are physical inactivity and increased BMI. With physical activity, it is possible ... ...

    Abstract Background: Cardiovascular diseases (CVDs) cause most deaths globally and can reduce quality of life (QoL) of rehabilitees with cardiac disease. The risk factors of CVDs are physical inactivity and increased BMI. With physical activity, it is possible to prevent CVDs, improve QoL, and help maintain a healthy body mass. Current literature shows the possibilities of digitalization and advanced technology in supporting independent self-rehabilitation. However, the interpretation of the results is complicated owing to the studies' high heterogeneity. In addition, the added value of this technology has not been studied well, especially in cardiac rehabilitation.
    Objective: We aimed to examine the effectiveness of added remote technology in cardiac rehabilitation on physical function, anthropometrics, and QoL in rehabilitees with CVD compared with conventional rehabilitation.
    Methods: Rehabilitees were cluster randomized into 3 remote technology intervention groups (n=29) and 3 reference groups (n=30). The reference group received conventional cardiac rehabilitation, and the remote technology intervention group received conventional cardiac rehabilitation with added remote technology, namely, the Movendos mCoach app and Fitbit charge accelerometer. The 12 months of rehabilitation consisted of three 5-day in-rehabilitation periods in the rehabilitation center. Between these periods were two 6-month self-rehabilitation periods. Outcome measurements included the 6-minute walk test, body mass, BMI, waist circumference, and World Health Organization QoL-BREF questionnaire at baseline and at 6 and 12 months. Between-group differences were assessed using 2-tailed t tests and Mann-Whitney U test. Within-group differences were analyzed using a paired samples t test or Wilcoxon signed-rank test.
    Results: Overall, 59 rehabilitees aged 41 to 66 years (mean age 60, SD 6 years; n=48, 81% men) were included in the study. Decrement in waist circumference (6 months: 1.6 cm; P=.04; 12 months: 3 cm; P<.001) and increment in self-assessed QoL were greater (environmental factors: 0.5; P=.02) in the remote technology intervention group than the reference group. Both groups achieved statistically significant improvements in the 6-minute walk test in both time frames (P=.01-.03). Additionally, the remote technology intervention group achieved statistically significant changes in the environmental domain at 0-6 months (P=.03) and waist circumference at both time frames (P=.01), and reference group achieve statistically significant changes in waist circumference at 0-6 months (P=.02).
    Conclusions: Remote cardiac rehabilitation added value to conventional cardiac rehabilitation in terms of waist circumference and QoL. The results were clinically small, but the findings suggest that adding remote technology to cardiac rehabilitation may increase beneficial health outcomes. There was some level of systematic error during rehabilitation intervention, and the sample size was relatively small. Therefore, care must be taken when generalizing the study results beyond the target population. To confirm assumptions of the added value of remote technology in rehabilitation interventions, more studies involving different rehabilitees with cardiac disease are required.
    Trial registration: ISRCTN Registry ISRCTN61225589; https://www.isrctn.com/ISRCTN61225589.
    MeSH term(s) Female ; Humans ; Male ; Middle Aged ; Body Mass Index ; Cardiac Rehabilitation ; Cardiovascular Diseases ; Exercise ; Heart Diseases ; Quality of Life ; Telemedicine
    Language English
    Publishing date 2023-04-12
    Publishing country Canada
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2028830-X
    ISSN 1438-8871 ; 1438-8871
    ISSN (online) 1438-8871
    ISSN 1438-8871
    DOI 10.2196/42455
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Exploring the early molecular pathogenesis of osteoarthritis using differential network analysis of human synovial fluid.

    Rydén, M / Sjögren, A / Önnerfjord, P / Turkiewicz, A / Tjörnstrand, J / Englund, M / Ali, N

    Molecular & cellular proteomics : MCP

    2024  , Page(s) 100785

    Abstract: The molecular mechanisms that drive the onset and development of osteoarthritis (OA) remain largely unknown. In this exploratory study, we used a proteomic platform (SOMAscan assay) to measure the relative abundance of over 6000 proteins in synovial ... ...

    Abstract The molecular mechanisms that drive the onset and development of osteoarthritis (OA) remain largely unknown. In this exploratory study, we used a proteomic platform (SOMAscan assay) to measure the relative abundance of over 6000 proteins in synovial fluid (SF) from knees of human donors with healthy or mildly degenerated tissues and knees with late stage OA from patients undergoing knee replacement surgery. Using linear mixed effects model, we estimated the differential abundance of 6251 proteins between the three groups. We found 583 proteins upregulated in the late-stage OA, including MMP1, MMP13 and IL6. Further, we selected 760 proteins (800 aptamers) based on absolute fold changes between healthy and mild degeneration group. To those, we applied Gaussian Graphical Models (GGMs) to analyze the conditional dependence of proteins and to identify key proteins and subnetworks involved in early OA pathogenesis. After regularization and stability selection, we identified 102 proteins involved in GGM networks. Notably, network complexity was lost in the protein graph for mild degeneration when compared to controls, suggesting a disruption in the regular protein interplay. Furthermore, among our main findings were several downregulated (in mild degeneration versus healthy) proteins with unique interactions in healthy group, one of which, SLCO5A1, have not previously been associated with OA. Our results suggest that this protein is important for healthy joint function. Further, our data suggests that SF proteomics, combined with GGMs, can reveal novel insights into the molecular pathogenesis and identification of biomarker candidates for early stage OA.
    Language English
    Publishing date 2024-05-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2075924-1
    ISSN 1535-9484 ; 1535-9476
    ISSN (online) 1535-9484
    ISSN 1535-9476
    DOI 10.1016/j.mcpro.2024.100785
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Frequency of apical periodontitis in root-filled teeth restored with post and core: A 5-year retrospective study.

    Johansson, Louise / Sjögren, Jakob Jonsson / Wirén, Anders / Eliasson, Alf / Frisk, Fredrik

    Clinical and experimental dental research

    2024  Volume 10, Issue 3, Page(s) e881

    Abstract: Background: In conjunction with post placement in root-filled teeth with periapical healthy conditions, root canal retreatment may be performed to improve the seal of the root canal. Whether root canal retreatment for technical reasons (retreatments in ... ...

    Abstract Background: In conjunction with post placement in root-filled teeth with periapical healthy conditions, root canal retreatment may be performed to improve the seal of the root canal. Whether root canal retreatment for technical reasons (retreatments in teeth without apical periodontitis (AP)) results in lower frequency of AP is unknown.
    Objective: To examine whether there is a difference in frequency of AP between roots with root canals retreated for technical reasons, and roots with root canals not retreated before post placement, with a minimum follow-up of 5 years. Also, to examine changes in root filling quality following root canal retreatment for technical reasons.
    Methods: This retrospective study included radiographs of 441 root-filled roots without periapical radiolucencies at baseline, scheduled for post and core treatment. Follow-up data for a minimum of 5 years were available for 305 roots (loss to follow-up 30.8%), 46 of which were retreated for technical reasons. Two calibrated observers assessed root filling sealing quality and length, respectively, and periapical status according to the Periapical Index. The main outcome of the study, AP, was used as the dependent variable and all analyses were performed at root level.
    Results: The overall frequency of AP at follow-up was 13.8%. The difference in frequency of AP between retreated (4.3%) and nonretreated (15.4%) root canals was not statistically significant, p = .061. Analyses including only roots with preoperatively inadequate root filling quality showed a statistically significant difference (p = .017) between the two treatment groups (2.4% vs. 22.9%).
    Conclusions: Root canal retreatment for technical reasons before post and core placement significantly reduces the frequency of AP in roots with inadequate root filling quality.
    MeSH term(s) Humans ; Retrospective Studies ; Periapical Periodontitis/therapy ; Female ; Male ; Middle Aged ; Adult ; Post and Core Technique ; Root Canal Therapy/methods ; Root Canal Therapy/statistics & numerical data ; Root Canal Therapy/adverse effects ; Retreatment/statistics & numerical data ; Aged ; Follow-Up Studies
    Language English
    Publishing date 2024-05-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2829558-4
    ISSN 2057-4347 ; 2057-4347
    ISSN (online) 2057-4347
    ISSN 2057-4347
    DOI 10.1002/cre2.881
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Family screening for neurodevelopmental problems and its associations with child cognitive function enable tailored treatment for childhood obesity.

    Dellenmark-Blom, Maria / Järvholm, Kajsa / Sjögren, Lovisa / Levinsson, Anna / Dahlgren, Jovanna

    Acta paediatrica (Oslo, Norway : 1992)

    2024  

    Abstract: Aim: To identify neurodevelopmental disorders in children with obesity, and investigate associations to cognitive functions as well as parents' self-reported neurodevelopmental problems.: Methods: Eighty children were included at two outpatient ... ...

    Abstract Aim: To identify neurodevelopmental disorders in children with obesity, and investigate associations to cognitive functions as well as parents' self-reported neurodevelopmental problems.
    Methods: Eighty children were included at two outpatient obesity clinics in Sweden 2018-2019. Of these, 50 children without previously diagnosed neurodevelopmental disorders were screened, and so were their parents. Children who screened positive for neurodevelopmental problems were referred to a specialised psychiatry unit for further diagnosis. Test results of cognitive functioning were compared with the norm and between study groups by neurodevelopmental diagnoses.
    Results: Of the screened families, 17/50 children were diagnosed by the psychiatric unit with attention deficit-hyperactivity disorder (ADHD) and 15/82 parents screened positive for neurodevelopmental problems. Having a mother who screened positive for neurodevelopmental problems was associated with child ADHD (p < 0.05). The children's full-scale intelligence quotient (92.86 ± 12.01, p < 0.001) and working memory index (90.62 ± 12.17, p < 0.001) were lower than the norm. Working memory index was lower in children with ADHD compared to without ADHD: 84.76 ± 9.58 versus 94.09 ± 12.29 (p ≤ 0.01). Executive constraints were associated with verbal deviances.
    Conclusion: Increased awareness is needed about the overlap between neurodevelopmental problems and obesity in obesity clinics.
    Language English
    Publishing date 2024-05-06
    Publishing country Norway
    Document type Journal Article
    ZDB-ID 203487-6
    ISSN 1651-2227 ; 0365-1436 ; 0803-5253
    ISSN (online) 1651-2227
    ISSN 0365-1436 ; 0803-5253
    DOI 10.1111/apa.17263
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Article ; Online: Human capital effects of one-on-one time with parents

    Sjögren, Anna / Ahlzén, Malin Tallås

    Evidence from a Swedish childcare access reform

    2022  

    Abstract: We study the effects of increased opportunities for one-on-one time with a parent during infancy on the human capital formation of children. To this end, we exploit a nationwide reform that mandated Swedish municipalities to offer childcare access for ... ...

    Abstract We study the effects of increased opportunities for one-on-one time with a parent during infancy on the human capital formation of children. To this end, we exploit a nationwide reform that mandated Swedish municipalities to offer childcare access for infants' older siblings, while parents were on parental leave to care for their infants. Survey data on childcare enrollment show that the reform had a significant impact on the childcare enrollment of older siblings. Using rich administrative data, we estimate intention-to-treat effects in a differences-in-differences setting, comparing infants with and without siblings of childcare age, pre- and post-reform, in municipalities that were affected the reform. We find no robust overall effects on the children's 6th grade test scores, but we find evidence of positive effects on test scores for sons of less than university educated mothers and daughters of highly educated mothers. Exploring potential pathways, we find no evidence of changes in quantity of parental time during infancy, pointing instead towards the role of improved quality of parent-child interactions as a result of less competition for parental time. We also find that improvements in physical and mental health in school age may have contributed to the positive effect for boys and a lower probability of having a younger sibling may have reduced competition for parental time further and contributed to the improved test scores for girls.
    Keywords ddc:330 ; I14 ; I21 ; J13 ; Human capital formation ; Parental time investments ; Cognitive development ; Parental leave ; Quasi-experiment
    Subject code 331
    Language English
    Publisher Uppsala: Institute for Evaluation of Labour Market and Education Policy (IFAU)
    Publishing country de
    Document type Book ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Exploring the impact of nursing home managers' leadership on staff job satisfaction, health and intention to leave in nursing homes.

    Backman, Annica / Lindkvist, Marie / Lövheim, Hugo / Sjögren, Karin / Edvardsson, David

    Journal of clinical nursing

    2023  Volume 32, Issue 19-20, Page(s) 7227–7237

    Abstract: Aims and objectives: To explore the impact of nursing home leadership and staffing characteristics on staff job satisfaction, health and intention to leave.: Background: The number of older people has outpaced growth in the nursing home workforce ... ...

    Abstract Aims and objectives: To explore the impact of nursing home leadership and staffing characteristics on staff job satisfaction, health and intention to leave.
    Background: The number of older people has outpaced growth in the nursing home workforce worldwide. Identifying predictors with the potential to positively impact staff job satisfaction, health and intentions to leave are important. Leadership of the nursing home manager can be one such predictor.
    Design: Cross-sectional design.
    Methods: A sample of 2985 direct care staff in 190 nursing homes in 43 randomly selected municipalities in Sweden completed surveys on leadership, job satisfaction, self-rated health and intention to leave (response rate 52%). Descriptive statistics and Generalised Estimating Equations were conducted. The STROBE reporting checklist was applied.
    Results: Nursing home managers' leadership was positively related to job satisfaction, self-rated health and low intention to leave. Lower staff educational levels were related to poorer health and lower job satisfaction.
    Conclusions: Nursing home leadership plays a significant role in the job satisfaction, self-reported health and intention to leave of direct care staff. Low education levels among staff seem to negatively influence staff health and job satisfaction, suggesting that educational initiatives for less-educated staff could be beneficial for improving staff health and job satisfaction.
    Relevance to clinical practice: Managers seeking to improve staff job satisfaction can consider how they support, coach and provide feedback. Recognising staff achievement at work can contribute to high job satisfaction. One important implication for managers is to offer continuing education to staff with lower or no education, given the large amount of uneducated direct care workers in aged care and the impact this may have on staff job satisfaction and health.
    No patient or public contribution: No patient or public contribution was required to outcome measures in this study. Direct care staff and managers contributed with data.
    MeSH term(s) Humans ; Aged ; Intention ; Leadership ; Job Satisfaction ; Cross-Sectional Studies ; Nursing Homes ; Surveys and Questionnaires ; Nursing Staff, Hospital ; Personnel Turnover
    Language English
    Publishing date 2023-06-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 1159483-4
    ISSN 1365-2702 ; 0962-1067 ; 1752-9816
    ISSN (online) 1365-2702
    ISSN 0962-1067 ; 1752-9816
    DOI 10.1111/jocn.16781
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The Effectiveness of Physical Activity-Promoting Web- and Mobile-Based Distance Weight Loss Interventions on Body Composition in Rehabilitation Settings: Systematic Review, Meta-analysis, and Meta-Regression Analysis.

    Lahtio, Heli / Rintala, Aki / Immonen, Jaakko / Sjögren, Tuulikki

    Journal of medical Internet research

    2022  Volume 24, Issue 3, Page(s) e25906

    Abstract: Background: Overweight and obesity are major problems worldwide, and they lead to an increased risk for several diseases. The use of technology in the treatment of obesity is promising, but in the existing literature, there is considerable uncertainty ... ...

    Abstract Background: Overweight and obesity are major problems worldwide, and they lead to an increased risk for several diseases. The use of technology in the treatment of obesity is promising, but in the existing literature, there is considerable uncertainty regarding its efficacy. In this review, we included web- and mobile-based weight loss interventions that were implemented remotely in rehabilitation settings.
    Objective: The aim of this systematic review is to study the effectiveness of physical activity-promoting web- and mobile-based distance weight loss interventions in rehabilitation settings on body composition in comparison with control groups that did not use technology.
    Methods: Studies were searched from 9 databases. The inclusion criteria were as follows: population: age 18-65 years; intervention: physical activity-promoting web- and mobile-based distance weight loss interventions; comparison: control groups without the use of technology; outcome: changes in BMI, waist circumference, or body fat percentage; study design: randomized controlled trial. The quality of the studies was assessed by 2 researchers. Meta-analysis was performed, and we also conducted a meta-regression analysis to evaluate the factors associated with the changes in body composition outcomes if statistical heterogeneity was observed.
    Results: The meta-analysis included 30 studies. The mean quality of the studies was 7 of 13 (SD 1.9; range 3-10). A statistically significant difference was observed in BMI (mean difference [MD] 0.83, 95% CI 0.51-1.15 kg/m
    Conclusions: Web- and mobile-based distance weight loss interventions significantly reduced BMI, waist circumference, and body fat percentage. Future studies should focus on the comparability of the intervention content. Future studies are needed to better understand weight loss and identify which components are essential in achieving it.
    Trial registration: PROSPERO CRD42016035831; https://tinyurl.com/7c93tvd4.
    MeSH term(s) Adolescent ; Adult ; Aged ; Body Composition ; Exercise ; Humans ; Middle Aged ; Overweight/therapy ; Regression Analysis ; Weight Loss ; Young Adult
    Language English
    Publishing date 2022-03-24
    Publishing country Canada
    Document type Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Review ; Systematic Review
    ZDB-ID 2028830-X
    ISSN 1438-8871 ; 1439-4456
    ISSN (online) 1438-8871
    ISSN 1439-4456
    DOI 10.2196/25906
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Mild Cognitive Impairment, Reversion Rates, and Associated Factors: Comparison of Two Diagnostic Approaches.

    Overton, Marieclaire / Sjögren, Benjamin / Elmståhl, Sölve / Rosso, Aldana

    Journal of Alzheimer's disease : JAD

    2022  Volume 91, Issue 2, Page(s) 585–601

    Abstract: Background: As mild cognitive impairment (MCI) is typically used to identify prodromal stages of dementia, it is essential to identify MCI criteria with high diagnostic stability and prediction of dementia. Moreover, further investigation into ... ...

    Abstract Background: As mild cognitive impairment (MCI) is typically used to identify prodromal stages of dementia, it is essential to identify MCI criteria with high diagnostic stability and prediction of dementia. Moreover, further investigation into pinpointing key factors for reversion is required to foresee future prognosis of MCI patients accurately.
    Objective: To explore disparities in diagnostic stability by examining reversion rates produced by two operationalizations of the MCI definition: the widely applied Petersen criteria and a version of the Neuropsychological (NP) criteria and to identify cognitive, lifestyle, and health related factors for reversion.
    Methods: MCI was retrospectively classified in a sample from the Swedish community-based study Good Aging in Skåne with the Petersen criteria (n = 744, median follow-up = 7.0 years) and the NP criteria (n = 375, median follow-up, 6.7 years), respectively. Poisson regression models estimated the effect of various factors on the likelihood of incident reversion.
    Results: Reversion rates were 323/744 (43.4%, 95% confidence intervals (CI): 39.8; 47.0) and 181/375 (48.3% 95% CI: 43.2; 53.5) for the Petersen criteria and NP criteria, respectively. Participants with impairment in a single cognitive domain, regular alcohol consumption, living with someone, older age, and lower body mass index had a higher likelihood of reverting to normal.
    Conclusion: Reversion rates were similar for Petersen and NP criteria indicating that one definition is not superior to the other regarding diagnostic stability. Additionally, the results highlight important aspects such as multiple domain MCI, cohabitation, and the role of alcohol on predicting the trajectory of those diagnosed with MCI.
    MeSH term(s) Humans ; Retrospective Studies ; Disease Progression ; Cognitive Dysfunction/diagnosis ; Cognitive Dysfunction/epidemiology ; Cognitive Dysfunction/psychology ; Aging/psychology ; Neuropsychological Tests ; Dementia/psychology
    Language English
    Publishing date 2022-12-03
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1440127-7
    ISSN 1875-8908 ; 1387-2877
    ISSN (online) 1875-8908
    ISSN 1387-2877
    DOI 10.3233/JAD-220597
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book ; Thesis: Immunological methods for detection of the pneumococcal C-polysaccharide

    Sjögren, Annmargret

    1987  

    Size Getr. Zählung : Ill., graph. Darst.
    Publishing country Sweden
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Stockholm, Karolinska Inst., Diss., 1987
    HBZ-ID HT003230102
    ISBN 91-7900-291-9 ; 978-91-7900-291-6
    Database Catalogue ZB MED Medicine, Health

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