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  1. Article: Assessment of airborne soy-hull allergen (Gly m 1) in the Port of Ancona, Italy.

    Antonicelli, L / Ruello, M L / Monsalve, R I / González, R / Fava, G / Bonifazi, F

    European annals of allergy and clinical immunology

    2010  Volume 42, Issue 5, Page(s) 178–185

    Abstract: ... to measure the airborne Gly m 1 allergen level in the seaport of Ancona in order assess the soybean-specific ... detected. The concentration of the airborne Gly m 1 was not coupled with the presence of the soy-carrying ... meteorological parameters quantifies the association with the atmospheric condition.: Conclusion: Airborne Gly m 1 is ...

    Abstract Background: Epidemic asthma outbreaks are potentially a very high-risk medical situation in seaport towns where large volumes of soybean are loaded and unloaded Airborne allergen assessment plays a pivotal role in evaluating the resulting environmental pollution.
    Objective: The aim of this study was to measure the airborne Gly m 1 allergen level in the seaport of Ancona in order assess the soybean-specific allergenic risk for the city.
    Methods: Allergen and PM10 were evaluated at progressive distances from the port area. Allergen analysis was performed by monoclonal antibody-based immunoassay on the sampled filters. Daily meteorological data were obtained from the local meteorological station. For estimating the assimilative capacity of the atmosphere, an approach based on dispersive ventilation coefficient was tried.
    Results: The allergen concentrations detected were low (range = 0.4-171 ng/m3). A decreasing gradient of the airborne allergen from the unloading area (22.1 +/- 41.2 ng/m3) to the control area (0.6 +/- 0.7 ng/m3) was detected. The concentration of the airborne Gly m 1 was not coupled with the presence of the soy-carrying ships in the port. A statistically significant relationship between airborne allergen, PM10 and local meteorological parameters quantifies the association with the atmospheric condition.
    Conclusion: Airborne Gly m 1 is part of the atmospheric dust of Ancona. The low level of this allergen seems consistent with the absence of asthma epidemic outbreak.
    MeSH term(s) Air/analysis ; Allergens/chemistry ; Allergens/immunology ; Antigens, Plant/adverse effects ; Antigens, Plant/chemistry ; Antigens, Plant/immunology ; Asthma/epidemiology ; Asthma/etiology ; Asthma/immunology ; Cities ; Environmental Exposure/adverse effects ; Environmental Monitoring ; Epidemics ; Epidemiological Monitoring ; Humans ; Italy ; Occupational Exposure/adverse effects ; Particulate Matter/adverse effects ; Plant Proteins/adverse effects ; Plant Proteins/chemistry ; Plant Proteins/immunology ; Population Groups ; Risk Assessment ; Glycine max/immunology
    Chemical Substances Allergens ; Antigens, Plant ; Gly m I protein, Glycine max ; Particulate Matter ; Plant Proteins
    Language English
    Publishing date 2010-08-05
    Publishing country Italy
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2105540-3
    ISSN 1764-1489 ; 0397-9148
    ISSN 1764-1489 ; 0397-9148
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: The challenges of defining and managing treatment-resistant depression in research and practice.

    Fava, Maurizio

    World psychiatry : official journal of the World Psychiatric Association (WPA)

    2023  Volume 22, Issue 3, Page(s) 350–351

    Language English
    Publishing date 2023-09-15
    Publishing country Italy
    Document type Editorial
    ZDB-ID 2236130-3
    ISSN 2051-5545 ; 1723-8617
    ISSN (online) 2051-5545
    ISSN 1723-8617
    DOI 10.1002/wps.21128
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  3. Article ; Online: How should we design future mechanistic and/or efficacy clinical trials?

    Fava, Maurizio

    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

    2023  Volume 49, Issue 1, Page(s) 197–204

    Abstract: The emergence of new molecular targets, together with the development of new approaches to neuropsychiatric diseases, involving psychedelics as well as gene and cell therapies, are creating the need to improve the efficiency of mechanistic and/or ... ...

    Abstract The emergence of new molecular targets, together with the development of new approaches to neuropsychiatric diseases, involving psychedelics as well as gene and cell therapies, are creating the need to improve the efficiency of mechanistic and/or efficacy clinical trials. This review article will discuss a number of issues that have hampered our ability to detect therapeutic signals, from excessive placebo/sham response rates to the imprecision of diagnostic and outcome assessments. In addition to reviewing the limitations of current efficacy and mechanistic neuropsychiatric clinical trials, this review presents some of the methodological approaches that may improve the overall performance of our neuropsychiatric trials, including the adoption of novel study designs such as the sequential parallel comparison design and independent confirmation of the appropriateness of subjects' enrollment. In addition, this review will discuss several designs that make mechanistic clinical trials more precise.
    MeSH term(s) Humans ; Research Design ; Outcome Assessment, Health Care
    Language English
    Publishing date 2023-05-26
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 639471-1
    ISSN 1740-634X ; 0893-133X
    ISSN (online) 1740-634X
    ISSN 0893-133X
    DOI 10.1038/s41386-023-01600-9
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  4. Book ; Online: Food and agribusiness in 2030

    Gray, Allan W. / Rodrigues, Jonny Mateus / Kalaki, Rafael Bordonal / Neves, Marcos Fava

    a roadmap

    2020  

    Author's details Marcos Fava Neves (coordinator) ; Allan W. Gray, Falvio Runkhe Valerio, Leticia Franco Martinez, Jonny Mateus Rodrigues, Rafael Bordonal Kalaki, Vitor Nardini Marques, Vinícius Cambaúva
    Language English
    Size 1 Online-Ressource (124 Seiten)
    Publisher Wageningen Academic Publishers
    Publishing place Wageningen
    Publishing country Netherlands
    Document type Book ; Online
    HBZ-ID HT020668850
    ISBN 978-90-8686-907-7 ; 9789086863549 ; 90-8686-907-6 ; 908686354X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article ; Online: Shadow Tomography from Emergent State Designs in Analog Quantum Simulators.

    McGinley, Max / Fava, Michele

    Physical review letters

    2023  Volume 131, Issue 16, Page(s) 160601

    Abstract: We introduce a method that allows one to infer many properties of a quantum state-including nonlinear functions such as Rényi entropies-using only global control over the constituent degrees of freedom. In this protocol, the state of interest is first ... ...

    Abstract We introduce a method that allows one to infer many properties of a quantum state-including nonlinear functions such as Rényi entropies-using only global control over the constituent degrees of freedom. In this protocol, the state of interest is first entangled with a set of ancillas under a fixed global unitary, before projective measurements are made. We show that when the unitary is sufficiently entangling, a universal relationship between the statistics of the measurement outcomes and properties of the state emerges, which can be connected to the recently discovered phenomeonon of emergent quantum state designs in chaotic systems. Thanks to this relationship, arbitrary observables can be reconstructed using the same number of experimental repetitions that would be required in classical shadow tomography [Huang et al., Nat. Phys. 16, 1050 (2020)NPAHAX1745-247310.1038/s41567-020-0932-7]. Unlike previous approaches to shadow tomography, our protocol can be implemented using only global Hamiltonian evolution, as opposed to qubit-selective logic gates, which makes it particularly well suited to analog quantum simulators, including ultracold atoms in optical lattices and arrays of Rydberg atoms.
    Language English
    Publishing date 2023-11-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.131.160601
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  6. Article ; Online: The Effects of Childhood Adversity and Self-Regulation on the Well-Being of Adults with Delinquency Histories: A Mediation Model.

    Rhoden-Neita, Michelle-Ann / Huang, Hui / Fava, Nicole M

    Journal of evidence-based social work (2019)

    2024  Volume 21, Issue 1, Page(s) 117–139

    Abstract: Purpose: Most youth with delinquency histories experience childhood adversity leaving them vulnerable to poor adult well-being. Previous research indicates that self-regulation difficulties could explain how childhood adversity affects adult well-being. ...

    Abstract Purpose: Most youth with delinquency histories experience childhood adversity leaving them vulnerable to poor adult well-being. Previous research indicates that self-regulation difficulties could explain how childhood adversity affects adult well-being. Yet, very few studies target adult self-regulation intervention. Therefore, this study examined the intervening effects of emerging adult self-regulation on the association between childhood adversity and adult well-being.
    Method: Using data from the first four waves of the Add Health Study, the researchers conducted structural equation modeling for mediation with bootstrapping. The researchers tested the mediation effects of emerging adult self-regulation on the association between childhood adversity (child maltreatment and violent victimization) and later adult well-being (mental health problems, alcohol and drug use, criminal behaviors) among people with delinquency histories and/or arrest prior to age 18 (
    Results: Several significant direct effects and one partial mediation effect were found. For example, child maltreatment significantly predicted adult mental health problems and criminal behaviors. Self-regulation (via the dissatisfaction with life and self subscale) mediated the association between child maltreatment and adult mental health problems.
    Discussion: Findings highlight the need for social workers to focus on prevention services and trauma-informed treatment for people with delinquency histories. In addition, evidence-based practice requires self-regulation interventions for adults with histories of childhood adversity and delinquency to focus on their emotional and cognitive functioning as well as self-esteem.
    Conclusion: Implementing self-regulation interventions during emerging adulthood can be useful to mitigate later adult mental health problems among people with histories of childhood adversity and delinquency.
    MeSH term(s) Adult ; Humans ; Adverse Childhood Experiences/statistics & numerical data ; Self-Control ; Adult Survivors of Child Adverse Events/psychology ; Latent Class Analysis
    Language English
    Publishing date 2024-01-03
    Publishing country United States
    Document type Journal Article
    ISSN 2640-8074
    ISSN (online) 2640-8074
    DOI 10.1080/26408066.2023.2265923
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  7. Article: Robert Kellner, M.D., Ph.D., 1922-1992.

    Fava, G A

    Psychosomatics

    1993  Volume 34, Issue 4, Page(s) 287–289

    MeSH term(s) Czechoslovakia ; History, 20th Century ; Psychosomatic Medicine/history ; United States
    Language English
    Publishing date 1993-07
    Publishing country England
    Document type Bibliography ; Biography ; Historical Article ; Journal Article
    ZDB-ID 209487-3
    ISSN 1545-7206 ; 0033-3182
    ISSN (online) 1545-7206
    ISSN 0033-3182
    DOI 10.1016/S0033-3182(93)71861-7
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  8. Article ; Online: Signatures of Fractional Statistics in Nonlinear Pump-Probe Spectroscopy.

    McGinley, Max / Fava, Michele / Parameswaran, S A

    Physical review letters

    2024  Volume 132, Issue 6, Page(s) 66702

    Abstract: We show that the presence of anyons in the excitation spectrum of a two-dimensional system can be inferred from nonlinear spectroscopic quantities. In particular, we consider pump-probe spectroscopy, where a sample is irradiated by two light pulses with ... ...

    Abstract We show that the presence of anyons in the excitation spectrum of a two-dimensional system can be inferred from nonlinear spectroscopic quantities. In particular, we consider pump-probe spectroscopy, where a sample is irradiated by two light pulses with an adjustable time delay between them. The relevant response coefficient exhibits a universal form that originates from the statistical phase acquired when anyons created by the first pulse braid around those created by the second. This behavior is shown to be qualitatively unchanged by nonuniversal physics including nonstatistical interactions and small nonzero temperatures. In magnetic systems, the signal of interest can be measured using currently available terahertz-domain probes, highlighting the potential usefulness of nonlinear spectroscopic techniques in the search for quantum spin liquids.
    Language English
    Publishing date 2024-02-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.132.066702
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  9. Article ; Online: A novel method of neurophysiological brainstem mapping in neurosurgery.

    Fava, Enrica / Colistra, Davide / Fragale, Maria / Cenzato, Marco

    Journal of neuroscience methods

    2024  Volume 405, Page(s) 110096

    Abstract: Background: Brainstem mapping with electrical stimulation allows functional identification of neural structures during resection of deep lesions. Single pulses or train of pulses are delivered to map cranial nerves and corticospinal tracts, respectively. ...

    Abstract Background: Brainstem mapping with electrical stimulation allows functional identification of neural structures during resection of deep lesions. Single pulses or train of pulses are delivered to map cranial nerves and corticospinal tracts, respectively.
    New method: We introduce a hybrid stimulation technique for mapping the brainstem. The stimulus consists of an electrical single pulse followed by a short train of 3-5 pulses at 500 Hz, at an interval of 60-75 ms. The responses to this stimulation pattern are recorded from appropriate cranial and limb muscles.
    Results: Both the single pulse and the short train elicit electromyographic responses when motor fibers or motor nuclei of the cranial nerves are stimulated. Responses to the train but not to the preceding single pulse indicate activation of the descending motor tracts, in the mesencephalon and the pons. Conversely, in the medulla, limb responses to stimulation of the corticospinal tracts are elicited by a single pulse. Identification of the extra and intra-axial courses of the trigeminal motor and sensory fibers is possible by recording responses from the masseter and the tongue muscles.
    Comparison with existing method(s): To date, either a pulse or a train is delivered during brainstem mapping, switching from one to the other modality according to the expected target structure. This procedure can be time-consuming and may even lead to false negative responses to the stimulation, eventually leading to inaccurate neurosurgical procedures.
    Conclusions: The novel hybrid pulse-train technique enhances the advantage of brainstem mapping procedure, minimizing pitfalls and improving patient safety.
    MeSH term(s) Humans ; Neurosurgery ; Monitoring, Intraoperative/methods ; Brain Stem/surgery ; Mesencephalon ; Neurosurgical Procedures/methods ; Electric Stimulation/methods ; Evoked Potentials, Motor/physiology
    Language English
    Publishing date 2024-02-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282721-9
    ISSN 1872-678X ; 0165-0270
    ISSN (online) 1872-678X
    ISSN 0165-0270
    DOI 10.1016/j.jneumeth.2024.110096
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  10. Article ; Online: Myocardial Matrix Hydrogels for Cardiac Repair: The Devil Is in the Details.

    Fava, Marika / Cannata, Antonio / Barallobre-Barreiro, Javier

    JACC. Basic to translational science

    2024  Volume 9, Issue 3, Page(s) 339–341

    Language English
    Publishing date 2024-03-28
    Publishing country United States
    Document type Editorial
    ISSN 2452-302X
    ISSN (online) 2452-302X
    DOI 10.1016/j.jacbts.2024.02.001
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