LIVIVO - Search results -

Search results

Result 1 - 10 of total 1664

Search options

Article ; Online: Crystal engineering: from promise to delivery.

Braga, Dario

Chemical communications (Cambridge, England)

2023 Volume 59, Issue 95, Page(s) 14052–14062

Abstract: Twenty years ago, I wrote ... ...

Abstract	Twenty years ago, I wrote a
Language	English
Publishing date	2023-11-28
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	1472881-3
ISSN	1364-548X ; 1359-7345 ; 0009-241X
ISSN (online)	1364-548X
ISSN	1359-7345 ; 0009-241X
DOI	10.1039/d3cc04313d
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Book ; Online: Traduzione di A China fica ao lado / La Cina è accanto

Braga, Maria Ondina / Graziani, Michela / Tylusinska-Kowalska, Anna

(Studi di Traduzione Letteraria Lusofona)

2022

Series title	Studi di Traduzione Letteraria Lusofona
Keywords	Literature & literary studies ; Maria Ondina Braga ; short stories ; translation ; Portuguese literature ; Macao
Language	Italian
Size	1 electronic resource (179 pages)
Publisher	Firenze University Press
Publishing place	Florence
Document type	Book ; Online
Note	Italian
HBZ-ID	HT030380054
ISBN	9788855186391 ; 8855186396
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Levofloxacin and Ciprofloxacin Co-Crystals with Flavonoids: Solid-State Investigation for a Multitarget Strategy against

Fiore, Cecilia / Antoniciello, Federico / Roncarati, Davide / Scarlato, Vincenzo / Grepioni, Fabrizia / Braga, Dario

Pharmaceutics

2024 Volume 16, Issue 2

Abstract: In this paper, we address the problem of antimicrobial resistance in the case ... ...

Abstract	In this paper, we address the problem of antimicrobial resistance in the case of
Language	English
Publishing date	2024-01-30
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527217-2
ISSN	1999-4923
ISSN	1999-4923
DOI	10.3390/pharmaceutics16020203
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: The Relevance of Crystal Forms in the Pharmaceutical Field: Sword of Damocles or Innovation Tools?

Braga, Dario / Casali, Lucia / Grepioni, Fabrizia

International journal of molecular sciences

2022 Volume 23, Issue 16

Abstract: This review is aimed to provide to an "educated but non-expert" readership and an overview of the scientific, commercial, and ethical importance of investigating the crystalline forms (polymorphs, hydrates, and co-crystals) of active pharmaceutical ... ...

Abstract	This review is aimed to provide to an "educated but non-expert" readership and an overview of the scientific, commercial, and ethical importance of investigating the crystalline forms (polymorphs, hydrates, and co-crystals) of active pharmaceutical ingredients (API). The existence of multiple crystal forms of an API is relevant not only for the selection of the best solid material to carry through the various stages of drug development, including the choice of dosage and of excipients suitable for drug development and marketing, but also in terms of intellectual property protection and/or extension. This is because the physico-chemical properties, such as solubility, dissolution rate, thermal stability, processability, etc., of the solid API may depend, sometimes dramatically, on the crystal form, with important implications on the drug's ultimate efficacy. This review will recount how the scientific community and the pharmaceutical industry learned from the catastrophic consequences of the appearance of new, more stable, and unsuspected crystal forms. The relevant aspects of hydrates, the most common pharmaceutical solid solvates, and of co-crystals, the association of two or more solid components in the same crystalline materials, will also be discussed. Examples will be provided of how to tackle multiple crystal forms with screening protocols and theoretical approaches, and ultimately how to turn into discovery and innovation the purposed preparation of new crystalline forms of an API.
MeSH term(s)	Crystallization ; Excipients ; Pharmaceutical Preparations ; Solubility
Chemical Substances	Excipients ; Pharmaceutical Preparations
Language	English
Publishing date	2022-08-12
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms23169013
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: The Relevance of Crystal Forms in the Pharmaceutical Field

Dario Braga / Lucia Casali / Fabrizia Grepioni

International Journal of Molecular Sciences, Vol 23, Iss 16, p

Sword of Damocles or Innovation Tools?

2022 Volume 9013

Abstract: This review is aimed to provide to an “educated but non-expert” readership and an overview of the scientific, commercial, and ethical importance of investigating the crystalline forms (polymorphs, hydrates, and co-crystals) of active pharmaceutical ... ...

Abstract	This review is aimed to provide to an “educated but non-expert” readership and an overview of the scientific, commercial, and ethical importance of investigating the crystalline forms (polymorphs, hydrates, and co-crystals) of active pharmaceutical ingredients (API). The existence of multiple crystal forms of an API is relevant not only for the selection of the best solid material to carry through the various stages of drug development, including the choice of dosage and of excipients suitable for drug development and marketing, but also in terms of intellectual property protection and/or extension. This is because the physico-chemical properties, such as solubility, dissolution rate, thermal stability, processability, etc., of the solid API may depend, sometimes dramatically, on the crystal form, with important implications on the drug’s ultimate efficacy. This review will recount how the scientific community and the pharmaceutical industry learned from the catastrophic consequences of the appearance of new, more stable, and unsuspected crystal forms. The relevant aspects of hydrates, the most common pharmaceutical solid solvates, and of co-crystals, the association of two or more solid components in the same crystalline materials, will also be discussed. Examples will be provided of how to tackle multiple crystal forms with screening protocols and theoretical approaches, and ultimately how to turn into discovery and innovation the purposed preparation of new crystalline forms of an API.
Keywords	crystal polymorphism ; hydrates ; co-crystals of active pharmaceuticals ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Subject code	540
Language	English
Publishing date	2022-08-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Searching for Suitable Kojic Acid Coformers: From Cocrystals and Salt to Eutectics.

Sun, Renren / Braun, Doris E / Casali, Lucia / Braga, Dario / Grepioni, Fabrizia

Crystal growth & design

2023 Volume 23, Issue 3, Page(s) 1874–1887

Abstract: The possibility of obtaining cocrystals of kojic acid with organic coformers has been investigated by both computational and experimental approaches. Cocrystallization attempts have been carried out with about 50 coformers, in different stoichiometric ... ...

Abstract	The possibility of obtaining cocrystals of kojic acid with organic coformers has been investigated by both computational and experimental approaches. Cocrystallization attempts have been carried out with about 50 coformers, in different stoichiometric ratios, by solution, slurry, and mechanochemical methods. Cocrystals were obtained with 3-hydroxybenzoic acid, imidazole, 4-pyridone, DABCO, and urotropine, while piperazine yielded a salt with the kojiate anion; cocrystallization with theophylline and 4-aminopyridine resulted in stoichiometric crystalline complexes that could not be described with certainty as cocrystals or salts. In the cases of panthenol, nicotinamide, urea, and salicylic acid the eutectic systems with kojic acid were investigated via differential scanning calorimetry. In all other preparations the resulting materials were constituted of a mixture of the reactants. All compounds were investigated by powder X-ray diffraction; the five cocrystals and the salt were fully characterized via single crystal X-ray diffraction. The stability of the cocrystals and the intermolecular interactions in all characterized compounds have been investigated by computational methods based on the electronic structure and pairwise energy calculations, respectively.
Language	English
Publishing date	2023-02-09
Publishing country	United States
Document type	Journal Article
ISSN	1528-7483
ISSN	1528-7483
DOI	10.1021/acs.cgd.2c01364
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Exploring the Co-Crystallization of Kojic Acid with Silver(I), Copper(II), Zinc(II), and Gallium(III) for Potential Antibacterial Applications

Renren Sun / Lucia Casali / Raymond J. Turner / Dario Braga / Fabrizia Grepioni

Molecules, Vol 28, Iss 1244, p

2023 Volume 1244

Abstract: Co-crystallization of kojic acid (HKA) with silver(I), copper(II), zinc(II), or gallium(III) salts yielded three 1D coordination polymers and one 0D complex in which kojic acid was present as a neutral or anionic terminal or bridging ligand. All ... ...

Abstract	Co-crystallization of kojic acid (HKA) with silver(I), copper(II), zinc(II), or gallium(III) salts yielded three 1D coordination polymers and one 0D complex in which kojic acid was present as a neutral or anionic terminal or bridging ligand. All reactions were conducted mechanochemically via ball milling and manual grinding, or via slurry. All solids were fully characterized via single-crystal and/or powder X-ray diffraction. As kojic acid is a mild antimicrobial compound that is widely used in cosmetics, and the metal cations possess antibacterial properties, their combinations were tested for potential antibacterial applications. The minimal inhibition concentrations (MICs) and minimal biocidal concentrations (MBCs) for all compounds were measured against standard strains of the bacteria P. aeruginosa , S. aureus , and E. coli . All compounds exerted appreciable antimicrobial activity in the order of silver, zinc, copper, and gallium complexes.
Keywords	antimicrobials ; antimicrobial metals ; silver ; copper ; gallium ; zinc ; Organic chemistry ; QD241-441
Subject code	540
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Exploring the Co-Crystallization of Kojic Acid with Silver(I), Copper(II), Zinc(II), and Gallium(III) for Potential Antibacterial Applications.

Sun, Renren / Casali, Lucia / Turner, Raymond J / Braga, Dario / Grepioni, Fabrizia

Molecules (Basel, Switzerland)

2023 Volume 28, Issue 3

Abstract	Co-crystallization of kojic acid (HKA) with silver(I), copper(II), zinc(II), or gallium(III) salts yielded three 1D coordination polymers and one 0D complex in which kojic acid was present as a neutral or anionic terminal or bridging ligand. All reactions were conducted mechanochemically via ball milling and manual grinding, or via slurry. All solids were fully characterized via single-crystal and/or powder X-ray diffraction. As kojic acid is a mild antimicrobial compound that is widely used in cosmetics, and the metal cations possess antibacterial properties, their combinations were tested for potential antibacterial applications. The minimal inhibition concentrations (MICs) and minimal biocidal concentrations (MBCs) for all compounds were measured against standard strains of the bacteria
MeSH term(s)	Zinc/chemistry ; Copper/chemistry ; Silver/pharmacology ; Silver/chemistry ; Gallium/pharmacology ; Staphylococcus aureus ; Escherichia coli ; Crystallization ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Anti-Infective Agents/pharmacology ; Acids ; Coordination Complexes/pharmacology ; Coordination Complexes/chemistry
Chemical Substances	Zinc (J41CSQ7QDS) ; Copper (789U1901C5) ; Silver (3M4G523W1G) ; kojic acid (6K23F1TT52) ; Gallium (CH46OC8YV4) ; Anti-Bacterial Agents ; Anti-Infective Agents ; Acids ; Coordination Complexes
Language	English
Publishing date	2023-01-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules28031244
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.MO 81: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Antimicrobial activity of supramolecular salts of gallium(III) and proflavine and the intriguing case of a trioxalate complex.

Guerrini, Marzia / d'Agostino, Simone / Grepioni, Fabrizia / Braga, Dario / Lekhan, Andrii / Turner, Raymond J

Scientific reports

2022 Volume 12, Issue 1, Page(s) 3673

Abstract: The use of the gallium oxalate complex [Ga(ox) ...

Abstract	The use of the gallium oxalate complex [Ga(ox)
MeSH term(s)	Anti-Bacterial Agents/pharmacology ; Escherichia coli ; Gallium/pharmacology ; Microbial Sensitivity Tests ; Oxalates/pharmacology ; Proflavine/pharmacology ; Pseudomonas aeruginosa ; Salts/pharmacology
Chemical Substances	Anti-Bacterial Agents ; Oxalates ; Salts ; Gallium (CH46OC8YV4) ; Proflavine (CY3RNB3K4T)
Language	English
Publishing date	2022-03-07
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-022-07813-0
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Comparison of Antimicrobial and Antibiofilm Activity of Proflavine Co-crystallized with Silver, Copper, Zinc, and Gallium Salts.

Lekhan, Andrii / Fiore, Cecilia / Shemchuk, Oleksii / Grepioni, Fabrizia / Braga, Dario / Turner, Raymond J

ACS applied bio materials

2022 Volume 5, Issue 9, Page(s) 4203–4212

Abstract: Here, we exploit our mechanochemical synthesis for co-crystallization of an organic antiseptic, proflavine, with metal-based antimicrobials (silver, copper, zinc, and gallium). Our previous studies have looked for general antimicrobial activity for the ... ...

Abstract	Here, we exploit our mechanochemical synthesis for co-crystallization of an organic antiseptic, proflavine, with metal-based antimicrobials (silver, copper, zinc, and gallium). Our previous studies have looked for general antimicrobial activity for the co-crystals: proflavine·AgNO
MeSH term(s)	Zinc/pharmacology ; Copper/pharmacology ; Silver/pharmacology ; Proflavine/pharmacology ; Gallium/pharmacology ; Salts/pharmacology ; Staphylococcus aureus ; Escherichia coli ; Anti-Infective Agents/pharmacology ; Bacteria ; Biofilms
Chemical Substances	Zinc (J41CSQ7QDS) ; Copper (789U1901C5) ; Silver (3M4G523W1G) ; Proflavine (CY3RNB3K4T) ; Gallium (CH46OC8YV4) ; Salts ; Anti-Infective Agents
Language	English
Publishing date	2022-08-15
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2576-6422
ISSN (online)	2576-6422
DOI	10.1021/acsabm.2c00404
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

Your last searches

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED