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  1. Article ; Online: Implementing Gentle Persuasive Approaches dementia education for staff on in-patient medicine units: A program evaluation.

    Crandall, Jacqueline / Coatsworth-Puspoky, Robin / Schlegel, Kimberly / Beker, Lyndsay / McLelland, Victoria C / Martin, Lori Schindel

    Dementia (London, England)

    2022  Volume 21, Issue 4, Page(s) 1173–1199

    Abstract: Older adults with dementia, when hospitalised, frequently experience responsive behaviours. Staff struggle to manage responsive behaviours without specific education. We aimed to enhance staff knowledge and confidence with care for older adults with ... ...

    Abstract Older adults with dementia, when hospitalised, frequently experience responsive behaviours. Staff struggle to manage responsive behaviours without specific education. We aimed to enhance staff knowledge and confidence with care for older adults with dementia and responsive behaviours on medicine units at a Canadian hospital. An online dementia education program was disseminated to staff as part of a broader quality improvement project. Gentle Persuasive Approaches (GPA) encourages staff to reframe responsive behaviours as self-protective expressions of unmet needs and learn to assess their meaning. Participants completed online quantitative and qualitative measures of self-efficacy, competence and knowledge in dementia care at three times: immediate pre-, immediate post- and six to eight weeks post-GPA eLearning. Immediately post-GPA, participants showed significant increases relative to baseline in dementia care self-efficacy, competence and knowledge. Self-efficacy scores increased further eight weeks post-GPA. Before GPA, few participants described dementia-specific strategies for de-escalating a patient's agitation. Eight weeks post-GPA, participants described application of tailored, person-centred, non-pharmacological interventions and successful application of GPA strategies. GPA eLearning strengthened staff preparedness to interact with older adults experiencing responsive behaviours, thus enhancing their care.
    MeSH term(s) Aged ; Canada ; Dementia/therapy ; Education, Distance ; Hospitals ; Humans ; Program Evaluation
    Language English
    Publishing date 2022-01-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2084045-7
    ISSN 1741-2684 ; 1471-3012
    ISSN (online) 1741-2684
    ISSN 1471-3012
    DOI 10.1177/14713012211070148
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Stimulus familiarity modulates functional connectivity of the perirhinal cortex and anterior hippocampus during visual discrimination of faces and objects.

    McLelland, Victoria C / Chan, David / Ferber, Susanne / Barense, Morgan D

    Frontiers in human neuroscience

    2014  Volume 8, Page(s) 117

    Abstract: Recent research suggests that the medial temporal lobe (MTL) is involved in perception as well as in declarative memory. Amnesic patients with focal MTL lesions and semantic dementia patients showed perceptual deficits when discriminating faces and ... ...

    Abstract Recent research suggests that the medial temporal lobe (MTL) is involved in perception as well as in declarative memory. Amnesic patients with focal MTL lesions and semantic dementia patients showed perceptual deficits when discriminating faces and objects. Interestingly, these two patient groups showed different profiles of impairment for familiar and unfamiliar stimuli. For MTL amnesics, the use of familiar relative to unfamiliar stimuli improved discrimination performance. By contrast, patients with semantic dementia-a neurodegenerative condition associated with anterolateral temporal lobe damage-showed no such facilitation from familiar stimuli. Given that the two patient groups had highly overlapping patterns of damage to the perirhinal cortex, hippocampus, and temporal pole, the neuroanatomical substrates underlying their performance discrepancy were unclear. Here, we addressed this question with a multivariate reanalysis of the data presented by Barense et al. (2011), using functional connectivity to examine how stimulus familiarity affected the broader networks with which the perirhinal cortex, hippocampus, and temporal poles interact. In this study, healthy participants were scanned while they performed an odd-one-out perceptual task involving familiar and novel faces or objects. Seed-based analyses revealed that functional connectivity of the right perirhinal cortex and right anterior hippocampus was modulated by the degree of stimulus familiarity. For familiar relative to unfamiliar faces and objects, both right perirhinal cortex and right anterior hippocampus showed enhanced functional correlations with anterior/lateral temporal cortex, temporal pole, and medial/lateral parietal cortex. These findings suggest that in order to benefit from stimulus familiarity, it is necessary to engage not only the perirhinal cortex and hippocampus, but also a network of regions known to represent semantic information.
    Language English
    Publishing date 2014-03-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2425477-0
    ISSN 1662-5161
    ISSN 1662-5161
    DOI 10.3389/fnhum.2014.00117
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Memories of the future: new insights into the adaptive value of episodic memory.

    Szpunar, Karl K / Addis, Donna Rose / McLelland, Victoria C / Schacter, Daniel L

    Frontiers in behavioral neuroscience

    2013  Volume 7, Page(s) 47

    Language English
    Publishing date 2013-05-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2452960-6
    ISSN 1662-5153
    ISSN 1662-5153
    DOI 10.3389/fnbeh.2013.00047
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Making the future memorable: The phenomenology of remembered future events.

    McLelland, Victoria C / Devitt, Aleea L / Schacter, Daniel L / Addis, Donna Rose

    Memory (Hove, England)

    2015  Volume 23, Issue 8, Page(s) 1255–1263

    Abstract: Although our ability to remember future simulations conveys an adaptive advantage, enabling us to better prepare for upcoming events, the factors influencing the memorability of future simulations are not clear. In this study, participants generated ... ...

    Abstract Although our ability to remember future simulations conveys an adaptive advantage, enabling us to better prepare for upcoming events, the factors influencing the memorability of future simulations are not clear. In this study, participants generated future simulations that combined specific people, places and objects from memory, and for each trial, made a series of phenomenological ratings about the event components and the simulation as a whole. Memory for simulations was later assessed using a cued-recall test. We used multilevel modelling to determine whether the phenomenological qualities of event components (familiarity, emotionality and significance) and simulations (detail, plausibility) were predictive of whether the simulation was successfully encoded and later accessible. Our results demonstrate that person familiarity, detail and plausibility were significant predictors of whether a given future simulation was encoded into memory and later accessible. These findings suggest that scaffolding future simulations with pre-existing episodic memories is the path to a memorable future.
    MeSH term(s) Adolescent ; Adult ; Cues ; Emotions ; Female ; Forecasting ; Humans ; Imagination ; Male ; Memory ; Memory, Episodic ; Mental Recall ; Models, Psychological ; Recognition (Psychology) ; Young Adult
    Language English
    Publishing date 2015
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1147478-6
    ISSN 1464-0686 ; 0965-8211
    ISSN (online) 1464-0686
    ISSN 0965-8211
    DOI 10.1080/09658211.2014.972960
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5983: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Hippocampal Functioning and Verbal Associative Memory in Adolescents with Congenital Hypothyroidism.

    Wheeler, Sarah M / McLelland, Victoria C / Sheard, Erin / McAndrews, Mary Pat / Rovet, Joanne F

    Frontiers in endocrinology

    2015  Volume 6, Page(s) 163

    Abstract: Thyroid hormone (TH) is essential for normal development of the hippocampus, which is critical for memory and particularly for learning and recalling associations between visual and verbal stimuli. Adolescents with congenital hypothyroidism (CH), who ... ...

    Abstract Thyroid hormone (TH) is essential for normal development of the hippocampus, which is critical for memory and particularly for learning and recalling associations between visual and verbal stimuli. Adolescents with congenital hypothyroidism (CH), who lack TH in late gestation and early life, demonstrate weak verbal recall abilities, reduced hippocampal volumes, and abnormal hippocampal functioning for visually associated material. However, it is not known if their hippocampus functions abnormally when remembering verbal associations. Our objective was to assess hippocampal functioning in CH using functional magnetic resonance imaging (fMRI). Fourteen adolescents with CH and 14 typically developing controls (TDC) were studied. Participants studied pairs of words and then, during fMRI acquisition, made two types of recognition decisions: in one they judged whether the pairs were the same as when seen originally and in the other, whether individual words were seen before regardless of pairing. Hippocampal activation was greater for pairs than items in both groups, but this difference was only significant in TDC. When we directly compared the groups, the right anterior hippocampus was the primary region in which the TDC and CH groups differed for this pair memory effect. Results signify that adolescents with CH show abnormal hippocampal functioning during verbal memory processing.
    Language English
    Publishing date 2015
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2015.00163
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Imagining the future: evidence for a hippocampal contribution to constructive processing.

    Gaesser, Brendan / Spreng, R Nathan / McLelland, Victoria C / Addis, Donna Rose / Schacter, Daniel L

    Hippocampus

    2013  Volume 23, Issue 12, Page(s) 1150–1161

    Abstract: Imagining future events and remembering past events rely on a common core network, but several regions within this network--including the hippocampus--show increased activity for imagining future events compared to remembering past events. It remains ... ...

    Abstract Imagining future events and remembering past events rely on a common core network, but several regions within this network--including the hippocampus--show increased activity for imagining future events compared to remembering past events. It remains unclear whether this hippocampal activity reflects processes related to the demands of constructing details retrieved across disparate episodic memories into coherent imaginary events, encoding these events into memory, novelty detection, or some combination of these processes. We manipulated the degree of constructive processing by comparing activity associated with the initial construction of an imagined scenario with the re-construction of an imagined scenario (imagine vs. re-imagine). After accounting for effects of novelty and subsequent memory, we found that a region in the hippocampus was preferentially activated for newly constructed imagined events compared with re-imagined events. Our results suggest that the hippocampus may support several distinct but related processes that are critical for imagining future events, and they also indicate that a particular region within posterior hippocampus may uniquely contribute to the construction of imagined future events.
    MeSH term(s) Adult ; Analysis of Variance ; Brain Mapping ; Female ; Hippocampus/blood supply ; Hippocampus/physiology ; Humans ; Image Processing, Computer-Assisted ; Imagination/physiology ; Judgment ; Magnetic Resonance Imaging ; Male ; Memory, Episodic ; Neuropsychological Tests ; Oxygen/blood ; Thinking/physiology ; Young Adult
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2013-07-10
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1074352-2
    ISSN 1098-1063 ; 1050-9631
    ISSN (online) 1098-1063
    ISSN 1050-9631
    DOI 10.1002/hipo.22152
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3227: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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