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  1. Article: Concurrent stroke and ST-elevation myocardial infarction: Is it a contraindication for intravenous tenecteplase?

    Wan Asyraf, W Z / Elengoe, S / Che Hassan, H H / Abu Bakar, A / Remli, R

    The Medical journal of Malaysia

    2020  Volume 75, Issue 2, Page(s) 169–170

    Abstract: Acute ischemic stroke (AIS) and acute ST-elevation myocardial infarction (STEMI) are leading causes of mortality worldwide. Concurrent AIS presentation with STEMI is rare and potentially fatal. Most importantly to date many centres in Malaysia are still ... ...

    Abstract Acute ischemic stroke (AIS) and acute ST-elevation myocardial infarction (STEMI) are leading causes of mortality worldwide. Concurrent AIS presentation with STEMI is rare and potentially fatal. Most importantly to date many centres in Malaysia are still not aware on how to treat this condition. We report a case of AIS, which was treated with intravenous tenecteplase (TNK) according to ischemic stroke dosage and lead to improvement of neurological deficit.
    MeSH term(s) Administration, Intravenous ; Adult ; Contraindications ; Fibrinolytic Agents/administration & dosage ; Humans ; Malaysia ; Male ; ST Elevation Myocardial Infarction/drug therapy ; Stroke/drug therapy ; Tenecteplase/administration & dosage
    Chemical Substances Fibrinolytic Agents ; Tenecteplase (WGD229O42W)
    Language English
    Publishing date 2020-04-11
    Publishing country Malaysia
    Document type Journal Article
    ZDB-ID 604286-7
    ISSN 0300-5283
    ISSN 0300-5283
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1206: Show issues Location:
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  2. Article: Quantitative vestibular function tests in posterior circulation stroke patients: A review.

    Sayed, S Z / Abdul Wahat, N H / Raymond, A A / Hussein, N / Wan Asyraf, W Z / Omar, M

    The Medical journal of Malaysia

    2021  Volume 76, Issue 6, Page(s) 898–905

    Abstract: While specific bedside examinations are known to be sensitive in identifying stroke among acute vestibular syndrome patients, complementary quantitative vestibular function testing can be helpful to quantify vestibular loss due to stroke. In contrast to ... ...

    Abstract While specific bedside examinations are known to be sensitive in identifying stroke among acute vestibular syndrome patients, complementary quantitative vestibular function testing can be helpful to quantify vestibular loss due to stroke. In contrast to peripheral vestibular dysfunction, diagnosis of central vestibular dysfunction can be challenging for unskilful clinicians. This article presents a comprehensive overview of quantitative vestibular function test findings such as the video head impulse test (vHIT), cervical vestibular evoked myogenic potentials (cVEMPs), ocular vestibular evoked myogenic potentials (oVEMPs), videonystagmography (VNG) and caloric test among stroke patients. Vestibulo-ocular reflex (VOR) gain is usually found normal among posterior inferior cerebellar artery (PICA) stroke patients but varies among anterior inferior cerebellar artery (AICA) stroke patients. Abnormal contralesional posterior semicircular canal VOR gain can be observed due to lesions in the medial longitudinal fasciculus (MLF). AICA and PICA stroke can impair cVEMPs, oVEMPs, and VNG (i.e., smooth pursuit and saccade functions). Strokes, particularly those involving the vestibular nucleus, including both upper, lower brainstem and cerebellum, can result in various abnormalities of smooth pursuit, saccade or calorics testing. The combined evaluations of VNG, vHIT, and VEMPs can be accurately used to complement and quantify bedside vestibular evaluation in diagnosing central vestibular dysfunction. In addition, as most studies were conducted amongst acute vestibular syndrome (AVS) patients, future studies that investigate the prevalence of vestibular dysfunction in recovering stroke patients are required.
    MeSH term(s) Head Impulse Test ; Humans ; Reflex, Vestibulo-Ocular/physiology ; Stroke/complications ; Stroke/diagnosis ; Vestibular Evoked Myogenic Potentials/physiology ; Vestibular Function Tests
    Language English
    Publishing date 2021-11-21
    Publishing country Malaysia
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 604286-7
    ISSN 0300-5283
    ISSN 0300-5283
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  3. Article: Malaysia Stroke Council guide on acute stroke care service during COVID-19 Pandemic.

    Wan Asyraf, W Z / Ah Khan, Y K / Chung, L W / Kee, H F / Irene, L / Ang, C L / Choon, W K / Mak, C S / Tan, W Y / Wn Nafisah, W Y / Hamidon, B

    The Medical journal of Malaysia

    2020  Volume 75, Issue 3, Page(s) 311–313

    Abstract: On the 18th of March 2020, the Malaysia government declared a movement control order (MCO) due to the unprecedented COVID-19 pandemic. Although the majority of patients presented with respiratory-related symptoms, COVID-19 patients may present atypically ...

    Abstract On the 18th of March 2020, the Malaysia government declared a movement control order (MCO) due to the unprecedented COVID-19 pandemic. Although the majority of patients presented with respiratory-related symptoms, COVID-19 patients may present atypically with neurological manifestations and may even have an increased risk of stroke. The Malaysia Stroke Council is concerned regarding the level of care given to stroke patients during this pandemic. During the recent National Stroke Workflow Steering Committee meeting, a guide was made based on the currently available evidences to assist Malaysian physicians providing acute stroke care in the hospital setting in order to provide the best stroke care while maintaining their own safety. The guide comprises of prehospital stroke awareness, hyperacute stroke care, stroke care unit and intensive care unit admission, post-stroke rehabilitation and secondary prevention practice. We urge continuous initiative to provide the best stroke care possible and ensure adequate safety for both patients and the stroke care team.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Humans ; Intensive Care Units ; Malaysia ; Pandemics ; Pneumonia, Viral/complications ; Practice Guidelines as Topic ; SARS-CoV-2 ; Stroke/diagnostic imaging ; Stroke/therapy ; Stroke Rehabilitation ; Tomography, X-Ray Computed
    Keywords covid19
    Language English
    Publishing date 2020-05-27
    Publishing country Malaysia
    Document type Journal Article
    ZDB-ID 604286-7
    ISSN 0300-5283
    ISSN 0300-5283
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  4. Article ; Online: Successful intravenous thrombolysis of a wake-up stroke with underlying valvular atrial fibrillation.

    Shahedah, K K / Khoo, C S / Wan Nur Nafisah, W Y / Ng, C F / Noor Ashikin, I / Mohd Naim, M Y / Syazarina Sharis, O / Rozman, Z / Wan Asyraf, W Z

    The journal of the Royal College of Physicians of Edinburgh

    2018  Volume 48, Issue 3, Page(s) 239–241

    Abstract: A 42-year-old female admitted with new-onset atrial fibrillation had a wake-up stroke on the high-dependency unit and the time last seen well (TLSW) was 6.5 h. She suffered left-sided body weakness and her National Institutes of Health Stroke Scale ( ... ...

    Abstract A 42-year-old female admitted with new-onset atrial fibrillation had a wake-up stroke on the high-dependency unit and the time last seen well (TLSW) was 6.5 h. She suffered left-sided body weakness and her National Institutes of Health Stroke Scale (NIHSS) score was 17. An emergency CT perfusion showed right M1 segment occlusion with more than 50% penumbra. She was given recombinant tissue plasminogen activator (r-tPA) at 9 h from TLSW. An immediate diagnostic angiogram with intention to treat, owing to the presence of large vessel occlusion, showed complete reperfusion after intravenous r-tPA. She was discharged with NIHSS of 2, and at 3-month follow up her Modified Rankin Scale was 0. We demonstrated a successful reperfusion and excellent clinical recovery with intravenous thrombolysis in a patient who presented with a wake-up stroke with underlying valvular atrial fibrillation despite evidence of large vessel occlusion.
    MeSH term(s) Administration, Intravenous ; Adult ; Atrial Fibrillation/complications ; Female ; Fibrinolytic Agents/administration & dosage ; Fibrinolytic Agents/therapeutic use ; Humans ; Recombinant Proteins/therapeutic use ; Reperfusion ; Stroke/diagnostic imaging ; Stroke/drug therapy ; Tissue Plasminogen Activator/administration & dosage ; Tissue Plasminogen Activator/therapeutic use
    Chemical Substances Fibrinolytic Agents ; Recombinant Proteins ; Tissue Plasminogen Activator (EC 3.4.21.68)
    Language English
    Publishing date 2018-10-09
    Publishing country Scotland
    Document type Case Reports ; Journal Article
    ZDB-ID 2866363-9
    ISSN 2042-8189 ; 0953-0932
    ISSN (online) 2042-8189
    ISSN 0953-0932
    DOI 10.4997/JRCPE.2018.308
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Malaysia Stroke Council guide on acute stroke care service during COVID-19 Pandemic

    Wan Asyraf, W Z / Ah Khan, Y K / Chung, L W / Kee, H F / Irene, L / Ang, C L / Choon, W K / Mak, C S / Tan, W Y / Wn Nafisah, W Y / Hamidon, B

    Med J Malaysia

    Abstract: On the 18th of March 2020, the Malaysia government declared a movement control order (MCO) due to the unprecedented COVID-19 pandemic. Although the majority of patients presented with respiratory-related symptoms, COVID-19 patients may present atypically ...

    Abstract On the 18th of March 2020, the Malaysia government declared a movement control order (MCO) due to the unprecedented COVID-19 pandemic. Although the majority of patients presented with respiratory-related symptoms, COVID-19 patients may present atypically with neurological manifestations and may even have an increased risk of stroke. The Malaysia Stroke Council is concerned regarding the level of care given to stroke patients during this pandemic. During the recent National Stroke Workflow Steering Committee meeting, a guide was made based on the currently available evidences to assist Malaysian physicians providing acute stroke care in the hospital setting in order to provide the best stroke care while maintaining their own safety. The guide comprises of prehospital stroke awareness, hyperacute stroke care, stroke care unit and intensive care unit admission, post-stroke rehabilitation and secondary prevention practice. We urge continuous initiative to provide the best stroke care possible and ensure adequate safety for both patients and the stroke care team.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #431972
    Database COVID19

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  6. Article ; Online: Global Impact of COVID-19 on Stroke Care and IV Thrombolysis.

    Nogueira, Raul G / Qureshi, Muhammad M / Abdalkader, Mohamad / Martins, Sheila Ouriques / Yamagami, Hiroshi / Qiu, Zhongming / Mansour, Ossama Yassin / Sathya, Anvitha / Czlonkowska, Anna / Tsivgoulis, Georgios / Aguiar de Sousa, Diana / Demeestere, Jelle / Mikulik, Robert / Vanacker, Peter / Siegler, James E / Kõrv, Janika / Biller, Jose / Liang, Conrad W / Sangha, Navdeep S /
    Zha, Alicia M / Czap, Alexandra L / Holmstedt, Christine Anne / Turan, Tanya N / Ntaios, George / Malhotra, Konark / Tayal, Ashis / Loochtan, Aaron / Ranta, Annamarei / Mistry, Eva A / Alexandrov, Anne W / Huang, David Y / Yaghi, Shadi / Raz, Eytan / Sheth, Sunil A / Mohammaden, Mahmoud H / Frankel, Michael / Bila Lamou, Eric Guemekane / Aref, Hany M / Elbassiouny, Ahmed / Hassan, Farouk / Menecie, Tarek / Mustafa, Wessam / Shokri, Hossam M / Roushdy, Tamer / Sarfo, Fred S / Alabi, Tolulope Oyetunde / Arabambi, Babawale / Nwazor, Ernest O / Sunmonu, Taofiki Ajao / Wahab, Kolawole / Yaria, Joseph / Mohammed, Haytham Hussein / Adebayo, Philip B / Riahi, Anis D / Sassi, Samia Ben / Gwaunza, Lenon / Ngwende, Gift Wilson / Sahakyan, David / Rahman, Aminur / Ai, Zhibing / Bai, Fanghui / Duan, Zhenhui / Hao, Yonggang / Huang, Wenguo / Li, Guangwen / Li, Wei / Liu, Ganzhe / Luo, Jun / Shang, Xianjin / Sui, Yi / Tian, Ling / Wen, Hongbin / Wu, Bo / Yan, Yuying / Yuan, Zhengzhou / Zhang, Hao / Zhang, Jun / Zhao, Wenlong / Zi, Wenjie / Leung, Thomas W / Chugh, Chandril / Huded, Vikram / Menon, Bindu / Pandian, Jeyaraj Durai / Sylaja, P N / Usman, Fritz Sumantri / Farhoudi, Mehdi / Hokmabadi, Elyar Sadeghi / Horev, Anat / Reznik, Anna / Sivan Hoffmann, Rotem / Ohara, Nobuyuki / Sakai, Nobuyuki / Watanabe, Daisuke / Yamamoto, Ryoo / Doijiri, Ryosuke / Tokuda, Naoki / Yamada, Takehiro / Terasaki, Tadashi / Yazawa, Yukako / Uwatoko, Takeshi / Dembo, Tomohisa / Shimizu, Hisao / Sugiura, Yuri / Miyashita, Fumio / Fukuda, Hiroki / Miyake, Kosuke / Shimbo, Junsuke / Sugimura, Yusuke / Yagita, Yoshiki / Takenobu, Yohei / Matsumaru, Yuji / Yamada, Satoshi / Kono, Ryuhei / Kanamaru, Takuya / Yamazaki, Hidekazu / Sakaguchi, Manabu / Todo, Kenichi / Yamamoto, Nobuaki / Sonoda, Kazutaka / Yoshida, Tomoko / Hashimoto, Hiroyuki / Nakahara, Ichiro / Kondybayeva, Aida / Faizullina, Kamila / Kamenova, Saltanat / Zhanuzakov, Murat / Baek, Jang-Hyun / Hwang, Yangha / Lee, Jin Soo / Lee, Si Baek / Moon, Jusun / Park, Hyungjong / Seo, Jung Hwa / Seo, Kwon-Duk / Sohn, Sung Il / Young, Chang Jun / Ahdab, Rechdi / Wan Zaidi, Wan Asyraf / Aziz, Zariah Abdul / Basri, Hamidon Bin / Chung, Law Wan / Ibrahim, Aznita Binti / Ibrahim, Khairul Azmi / Looi, Irene / Tan, Wee Yong / Yahya, Nafisah Wan / Groppa, Stanislav / Leahu, Pavel / Al Hashmi, Amal M / Imam, Yahia Zakaria / Akhtar, Naveed / Pineda-Franks, Maria Carissa / Co, Christian Oliver / Kandyba, Dmitriy / Alhazzani, Adel / Al-Jehani, Hosam / Tham, Carol Huilian / Mamauag, Marlie Jane / Venketasubramanian, Narayanaswamy / Chen, Chih-Hao / Tang, Sung-Chun / Churojana, Anchalee / Akil, Esref / Aykaç, Özlem / Ozdemir, Atilla Ozcan / Giray, Semih / Hussain, Syed Irteza / John, Seby / Le Vu, Huynh / Tran, Anh Duc / Nguyen, Huy Hoang / Nhu Pham, Thong / Nguyen, Thang Huy / Nguyen, Trung Quoc / Gattringer, Thomas / Enzinger, Christian / Killer-Oberpfalzer, Monika / Bellante, Flavio / De Blauwe, Sofie / Vanhooren, Geert / De Raedt, Sylvie / Dusart, Anne / Lemmens, Robin / Ligot, Noemie / Pierre Rutgers, Matthieu / Yperzeele, Laetitia / Alexiev, Filip / Sakelarova, Teodora / Bedeković, Marina Roje / Budincevic, Hrvoje / Cindric, Igor / Hucika, Zlatko / Ozretic, David / Saric, Majda Seferovic / Pfeifer, František / Karpowic, Igor / Cernik, David / Sramek, Martin / Skoda, Miroslav / Hlavacova, Helena / Klecka, Lukas / Koutny, Martin / Vaclavik, Daniel / Skoda, Ondrej / Fiksa, Jan / Hanelova, Katerina / Nevsimalova, Miroslava / Rezek, Robert / Prochazka, Petr / Krejstova, Gabriela / Neumann, Jiri / Vachova, Marta / Brzezanski, Henryk / Hlinovsky, David / Tenora, Dusan / Jura, Rene / Jurák, Lubomír / Novak, Jan / Novak, Ales / Topinka, Zdenek / Fibrich, Petr / Sobolova, Helena / Volny, Ondrej / Krarup Christensen, Hanne / Drenck, Nicolas / Klingenberg Iversen, Helle / Simonsen, Claus Z / Truelsen, Thomas Clement / Wienecke, Troels / Vibo, Riina / Gross-Paju, Katrin / Toomsoo, Toomas / Antsov, Katrin / Caparros, Francois / Cordonnier, Charlotte / Dan, Maria / Faucheux, Jean-Marc / Mechtouff, Laura / Eker, Omer / Lesaine, Emilie / Ondze, Basile / Peres, Roxane / Pico, Fernando / Piotin, Michel / Pop, Raoul / Rouanet, Francois / Gubeladze, Tatuli / Khinikadze, Mirza / Lobjanidze, Nino / Tsiskaridze, Alexander / Nagel, Simon / Ringleb, Peter Arthur / Rosenkranz, Michael / Schmidt, Holger / Sedghi, Annahita / Siepmann, Timo / Szabo, Kristina / Thomalla, Götz / Palaiodimou, Lina / Sagris, Dimitrios / Kargiotis, Odysseas / Klivenyi, Peter / Szapary, Laszlo / Tarkanyi, Gabor / Adami, Alessandro / Bandini, Fabio / Calabresi, Paolo / Frisullo, Giovanni / Renieri, Leonardo / Sangalli, Davide / Pirson, Anne / Uyttenboogaart, Maarten / van den Wijngaard, Ido / Kristoffersen, Espen Saxhaug / Brola, Waldemar / Fudala, Małgorzata / Horoch-Lyszczarek, Ewa / Karlinski, Michal / Kazmierski, Radoslaw / Kram, Pawel / Rogoziewicz, Marcin / Kaczorowski, Rafal / Luchowski, Piotr / Sienkiewicz-Jarosz, Halina / Sobolewski, Piotr / Fryze, Waldemar / Wisniewska, Anna / Wiszniewska, Malgorzata / Ferreira, Patricia / Ferreira, Paulo / Fonseca, Luisa / Marto, João Pedro / Pinho E Melo, Teresa / Nunes, Ana Paiva / Rodrigues, Miguel / Tedim Cruz, Vítor / Falup-Pecurariu, Cristian / Krastev, Georgi / Mako, Miroslav / de Leciñana, María Alonso / Arenillas, Juan F / Ayo-Martin, Oscar / Cruz Culebras, Antonio / Tejedor, Exuperio Diez / Montaner, Joan / Pérez-Sánchez, Soledad / Tola Arribas, Miguel Angel / Rodriguez Vasquez, Alejandro / Mayza, Michael / Bernava, Gianmarco / Brehm, Alex / Machi, Paolo / Fischer, Urs / Gralla, Jan / Michel, Patrik L / Psychogios, Marios-Nikos / Strambo, Davide / Banerjee, Soma / Krishnan, Kailash / Kwan, Joseph / Butt, Asif / Catanese, Luciana / Demchuk, Andrew M / Field, Thalia / Haynes, Jennifer / Hill, Michael D / Khosravani, Houman / Mackey, Ariane / Pikula, Aleksandra / Saposnik, Gustavo / Scott, Courtney Anne / Shoamanesh, Ashkan / Shuaib, Ashfaq / Yip, Samuel / Barboza, Miguel A / Barrientos, Jose Domingo / Portillo Rivera, Ligia Ibeth / Gongora-Rivera, Fernando / Novarro-Escudero, Nelson / Blanco, Anmylene / Abraham, Michael / Alsbrook, Diana / Altschul, Dorothea / Alvarado-Ortiz, Anthony J / Bach, Ivo / Badruddin, Aamir / Barazangi, Nobl / Brereton, Charmaine / Castonguay, Alicia / Chaturvedi, Seemant / Chaudry, Saqib A / Choe, Hana / Choi, Jae H / Dharmadhikari, Sushrut / Desai, Kinjal / Devlin, Thomas G / Doss, Vinodh T / Edgell, Randall / Etherton, Mark / Farooqui, Mudassir / Frei, Don / Gandhi, Dheeraj / Grigoryan, Mikayel / Gupta, Rishi / Hassan, Ameer E / Helenius, Johanna / Kaliaev, Artem / Kaushal, Ritesh / Khandelwal, Priyank / Khawaja, Ayaz M / Khoury, Naim N / Kim, Benny S / Kleindorfer, Dawn O / Koyfman, Feliks / Lee, Vivien H / Leung, Lester Y / Linares, Guillermo / Linfante, Italo / Lutsep, Helmi L / Macdougall, Lisa / Male, Shailesh / Malik, Amer M / Masoud, Hesham / McDermott, Molly / Mehta, Brijesh P / Min, Jiangyong / Mittal, Manoj / Morris, Jane G / Multani, Sumeet S / Nahab, Fadi / Nalleballe, Krishna / Nguyen, Claude B / Novakovic-White, Roberta / Ortega-Gutierrez, Santiago / Rahangdale, Rahul H / Ramakrishnan, Pankajavalli / Romero, Jose Rafael / Rost, Natalia / Rothstein, Aaron / Ruland, Sean / Shah, Ruchir / Sharma, Malveeka / Silver, Brian / Simmons, Marc / Singh, Abhishek / Starosciak, Amy K / Strasser, Sheryl L / Szeder, Viktor / Teleb, Mohamed / Tsai, Jenny P / Voetsch, Barbara / Balaguera, Oscar / Pujol Lereis, Virginia A / Luraschi, Adriana / Almeida, Marcele Schettini / Cardoso, Fabricio Buchdid / Conforto, Adriana / De Deus Silva, Leonardo / Varrone Giacomini, Luidia / Oliveira Lima, Fabricio / Longo, Alexandre L / Magalhães, Pedro S C / Martins, Rodrigo Targa / Mont'alverne, Francisco / Mora Cuervo, Daissy Liliana / Costa Rebello, Leticia / Valler, Lenise / Zetola, Viviane Flumignan / Lavados, Pablo M / Navia, Victor / Olavarría, Verónica V / Almeida Toro, Juan Manuel / Amaya, Pablo Felipe Ricardo / Bayona, Hernan / Corredor, Angel / Rivera Ordonez, Carlos Eduardo / Mantilla Barbosa, Diana Katherine / Lara, Osvaldo / Patiño, Mauricio R / Diaz Escobar, Luis Fernando / Dejesus Melgarejo Fariña, Donoband Edson / Cardozo Villamayor, Analia / Zelaya Zarza, Adolfo Javier / Barrientos Iman, Danny Moises / Rodriguez Kadota, Liliana / Campbell, Bruce / Hankey, Graeme J / Hair, Casey / Kleinig, Timothy / Ma, Alice / Tomazini Martins, Rodrigo / Sahathevan, Ramesh / Thijs, Vincent / Salazar, Daniel / Yuan-Hao Wu, Teddy / Haussen, Diogo C / Liebeskind, David / Yavagal, Dileep R / Jovin, Tudor G / Zaidat, Osama O / Nguyen, Thanh N

    Neurology

    2021  Volume 96, Issue 23, Page(s) e2824–e2838

    Abstract: Objective: To measure the global impact of COVID-19 pandemic on volumes of IV thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the pandemic (March 1 to June 30, 2020) compared with 2 control 4-month periods.!# ...

    Abstract Objective: To measure the global impact of COVID-19 pandemic on volumes of IV thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the pandemic (March 1 to June 30, 2020) compared with 2 control 4-month periods.
    Methods: We conducted a cross-sectional, observational, retrospective study across 6 continents, 70 countries, and 457 stroke centers. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases.
    Results: There were 91,373 stroke admissions in the 4 months immediately before compared to 80,894 admissions during the pandemic months, representing an 11.5% (95% confidence interval [CI] -11.7 to -11.3,
    Conclusions: The COVID-19 pandemic was associated with a global decline in the volume of stroke hospitalizations, IVT, and interfacility IVT transfers. Primary stroke centers and centers with higher COVID-19 inpatient volumes experienced steeper declines. Recovery of stroke hospitalization was noted in the later pandemic months.
    MeSH term(s) COVID-19 ; Cross-Sectional Studies ; Hospitalization ; Humans ; Pandemics ; Retrospective Studies ; SARS-CoV-2 ; Stroke/drug therapy ; Stroke/epidemiology ; Thrombolytic Therapy
    Language English
    Publishing date 2021-03-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000011885
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events: A 1-Year Follow-up.

    Nguyen, Thanh N / Qureshi, Muhammad M / Klein, Piers / Yamagami, Hiroshi / Mikulik, Robert / Czlonkowska, Anna / Abdalkader, Mohamad / Sedova, Petra / Sathya, Anvitha / Lo, Hannah C / Mansour, Ossama Yassin / Vanguru, Husitha Reddy / Lesaine, Emilie / Tsivgoulis, Georgios / Loochtan, Aaron I / Demeestere, Jelle / Uchino, Ken / Inoa, Violiza / Goyal, Nitin /
    Charidimou, Andreas / Siegler, James E / Yaghi, Shadi / Aguiar de Sousa, Diana / Mohammaden, Mahmoud H / Haussen, Diogo C / Kristoffersen, Espen Saxhaug / Lereis, Virginia Pujol / Scollo, Sergio Daniel / Campbell, Bruce C V / Ma, Alice / Thomas, James Orton / Parsons, Mark W / Singhal, Shaloo / Slater, Lee-Anne / Tomazini Martins, Rodrigo / Enzinger, Chris / Gattringer, Thomas / Rahman, Aminur / Bonnet, Thomas / Ligot, Noemie / De Raedt, Sylvie / Lemmens, Robin / Vanacker, Peter / Vandervorst, Fenne / Conforto, Adriana Bastos / Hidalgo, Raquel C T / de Oliveira Neves, Luciana / Martins, Rodrigo Targa / Mora Cuervo, Daissy Liliana / Rebello, Leticia C / Santiago, Igor Bessa / Lameirinhas da Silva, Isabelle / Sakelarova, Teodora / Kalpachki, Rosen / Alexiev, Filip / Catanese, Luciana / Cora, Elena Adela / Goyal, Mayank / Hill, Michael D / Kelly, Michael E / Khosravani, Houman / Lavoie, Pascale / Peeling, Lissa / Pikula, Aleksandra / Rivera, Rodrigo / Chen, Hui-Sheng / Chen, Yimin / 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Miyashita, Fumio / Tokuda, Naoki / Matsumaru, Yuji / Matsumoto, Shoji / Ohara, Nobuyuki / Shindo, Seigo / Takenobu, Yohei / Yoshimoto, Takeshi / Toyoda, Kazunori / Uwatoko, Takeshi / Yagita, Yoshiki / Yamada, Takehiro / Yamamoto, Nobuaki / Yamamoto, Ryoo / Yazawa, Yukako / Sugiura, Yuri / Waweru, Peter Kuria / Baek, Jang-Hyun / Lee, Si Baek / Seo, Kwon-Duk / Sohn, Sung-Il / Arsovska, Anita Ante / Chan, Yong Chieh / Wan Zaidi, Wan Asyraf / Jaafar, Ainul Syahrilfazli / Gongora-Rivera, Fernando / Martinez-Marino, Manuel / Infante-Valenzuela, Adrian / Groppa, Stanislav / Leahu, Pavel / Coutinho, Jonathan M / Rinkel, Leon A / Dippel, Diederik W J / van Dam-Nolen, Dianne H K / Ranta, Annemarei / Wu, Teddy Y / Adebayo, Tajudeen Temitayo / Bello, Abiodun H / Nwazor, Ernest Okwundu / Sunmonu, Taofiki Ajao / Wahab, Kolawole Wasiu / Ronning, Ole Morten / Sandset, Else Charlotte / Al Hashmi, Amal M / Ahmad, Saima / Rashid, Umair / Rodriguez-Kadota, Liliana / Vences, Miguel Ángel / Yalung, Patrick 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    Neurology

    2022  Volume 100, Issue 4, Page(s) e408–e421

    Abstract: Background and objectives: Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term effect of the pandemic on ... ...

    Abstract Background and objectives: Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term effect of the pandemic on stroke volumes over the course of a year and through the second wave of the pandemic. We sought to measure the effect of the COVID-19 pandemic on the volumes of stroke admissions, intracranial hemorrhage (ICH), IVT, and mechanical thrombectomy over a 1-year period at the onset of the pandemic (March 1, 2020, to February 28, 2021) compared with the immediately preceding year (March 1, 2019, to February 29, 2020).
    Methods: We conducted a longitudinal retrospective study across 6 continents, 56 countries, and 275 stroke centers. We collected volume data for COVID-19 admissions and 4 stroke metrics: ischemic stroke admissions, ICH admissions, IVT treatments, and mechanical thrombectomy procedures. Diagnoses were identified by their
    Results: There were 148,895 stroke admissions in the 1 year immediately before compared with 138,453 admissions during the 1-year pandemic, representing a 7% decline (95% CI [95% CI 7.1-6.9];
    Discussion: There was a global decline and shift to lower-volume centers of stroke admission volumes, ICH volumes, and IVT volumes during the 1st year of the COVID-19 pandemic compared with the prior year. Mechanical thrombectomy volumes were preserved. These results suggest preservation in the stroke care of higher severity of disease through the first pandemic year.
    Trial registration information: This study is registered under NCT04934020.
    MeSH term(s) Humans ; Brain Ischemia/therapy ; COVID-19/epidemiology ; COVID-19/therapy ; Follow-Up Studies ; Intracranial Hemorrhages ; Pandemics ; Retrospective Studies ; SARS-CoV-2 ; Stroke/epidemiology ; Stroke/therapy ; Stroke/diagnosis ; Stroke Volume ; Thrombectomy ; Thrombolytic Therapy/methods ; Treatment Outcome
    Language English
    Publishing date 2022-10-18
    Publishing country United States
    Document type Clinical Study ; Journal Article
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000201426
    Database MEDical Literature Analysis and Retrieval System OnLINE

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