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  1. Article ; Online: Changing Paradigms in the Treatment of Brain Metastases.

    Stupp, Roger

    Journal of oncology practice

    2019  Volume 15, Issue 11, Page(s) 573–574

    MeSH term(s) Brain Neoplasms ; Carcinoma, Non-Small-Cell Lung ; Humans ; Lung Neoplasms
    Language English
    Publishing date 2019-11-12
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2236338-5
    ISSN 1935-469X ; 1554-7477
    ISSN (online) 1935-469X
    ISSN 1554-7477
    DOI 10.1200/JOP.19.00602
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Thesis: Einheilverhalten orthotoper Gelenkreplantate nach extrakorporaler Bestrahlung

    Stupp, Reiner

    klinische, makroskopische und histologische Bewertung

    2003  

    Author's details vorgelegt von Reiner Stupp
    Language German
    Size 82, [6] Bl. : Ill., graph. Darst., 30 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Heidelberg, Univ., Diss., 2004
    HBZ-ID HT013999337
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2004 E 1168 order for loan Magazin

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  3. Article ; Online: Drug development for glioma: are we repeating the same mistakes?

    Stupp, Roger

    The Lancet. Oncology

    2018  Volume 20, Issue 1, Page(s) 10–12

    MeSH term(s) Drug Development ; Glioblastoma ; Glioma ; Humans ; Lomustine ; Phenylurea Compounds ; Pyridines
    Chemical Substances Phenylurea Compounds ; Pyridines ; regorafenib (24T2A1DOYB) ; Lomustine (7BRF0Z81KG)
    Language English
    Publishing date 2018-12-03
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(18)30827-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5696: Show issues Location:
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    Zs.MO 460: Show issues

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  4. Article: Editorial. Neuro-Oncology - Expertise at the Crossroads of Disciplines

    Stupp, R.

    Schweizer Krebs-Bulletin

    2018  Volume 38, Issue 2, Page(s) 109–110

    Language English ; French ; German
    Document type Article
    ZDB-ID 1340924-4
    Database Current Contents Medicine

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    Zs.A 4528: Show issues Location:
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  5. Book ; Thesis: Lymphozyten-Subtypisierung in der bronchoalveolären Lavage und im peripheren Blut bei interstitiellen Pneumopathien

    Stupp, Roger

    1995  

    Author's details vorgelegt von Roger Stupp
    Language German
    Size 53 Bl. : graph. Darst.
    Publishing country Switzerland
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Zürich, Univ., Diss., 1995
    HBZ-ID HT007563136
    Database Catalogue ZB MED Medicine, Health

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  6. Article: The Role of Switzerland in the EORTC

    Stupp, R.

    Schweizer Krebs-Bulletin

    2016  Volume 36, Issue 2, Page(s) 128–129

    Language English ; French ; German
    Document type Article
    ZDB-ID 1340924-4
    Database Current Contents Medicine

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    Zs.A 4528: Show issues Location:
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  7. Article: Overcoming the Blood-Brain Barrier with an Implantable Ultrasound Device.

    Sonabend, Adam M / Stupp, Roger

    Clinical cancer research : an official journal of the American Association for Cancer Research

    2019  Volume 25, Issue 13, Page(s) 3750–3752

    Abstract: Ultrasound-based blood-brain barrier disruption enhances drug delivery. To bypass the human skull, an implantable ultrasound emitter was developed, and proven safe and feasible in a first-in-human trial. Next development steps aim for larger field of ... ...

    Abstract Ultrasound-based blood-brain barrier disruption enhances drug delivery. To bypass the human skull, an implantable ultrasound emitter was developed, and proven safe and feasible in a first-in-human trial. Next development steps aim for larger field of disruption, quantification of drug levels, use of various drugs, and ultimately a pivotal trial demonstrating improved outcome.
    MeSH term(s) Blood-Brain Barrier ; Brain ; Drug Delivery Systems ; Humans ; Pharmaceutical Preparations ; Ultrasonography
    Chemical Substances Pharmaceutical Preparations
    Language English
    Publishing date 2019-05-10
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1225457-5
    ISSN 1557-3265 ; 1078-0432
    ISSN (online) 1557-3265
    ISSN 1078-0432
    DOI 10.1158/1078-0432.CCR-19-0932
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4223: Show issues Location:
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  8. Article: Stellungnahme zur Arbeit von H.M. Loick, R. Höing, C. Anger, G. Brodner und J.-L. Theissen: "Prophylaktische Glukokortikoidgabe vor Mikrolaryngoskopien".

    Möhrke, T / Pützhofen, G / Franke, W / Stupp, H F

    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS

    1993  Volume 28, Issue 2, Page(s) 128

    Title translation Comment on the contribution by H. M. Loick, R. Höing, C. Anger, G. Brodner and J.-L. Theissen: "Preventive glucocorticoid administration before microlaryngoscopies.
    MeSH term(s) Adolescent ; Adult ; Female ; Glucocorticoids/administration & dosage ; Humans ; Laryngeal Edema/prevention & control ; Laryngoscopy ; Male ; Middle Aged ; Premedication
    Chemical Substances Glucocorticoids
    Language German
    Publishing date 1993-04
    Publishing country Germany
    Document type Comment ; Letter
    ZDB-ID 1065682-0
    ISSN 1439-1074 ; 0939-2661
    ISSN (online) 1439-1074
    ISSN 0939-2661
    DOI 10.1055/s-2007-998892
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 257: Show issues Location:
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    Zs.MO 96: Show issues
    Zs.A 257/X: Show issues Location:
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  9. Article ; Online: Systemic peptide amphiphile nanofiber delivery following subcutaneous injection.

    Barlek, Mark H / Gillis, David C / Egner, Simon A / Maragos, Sophia L / Karver, Mark R / Stupp, Samuel I / Tsihlis, Nick D / Kibbe, Melina R

    Biomaterials

    2023  Volume 303, Page(s) 122401

    Abstract: Peptide amphiphile (PA) nanofibers have been shown to target and deliver drugs when administered via an intravenous (IV) injection. Subcutaneous administration can broaden the applicability of PA nanofibers in the medical field. The ability of PA ... ...

    Abstract Peptide amphiphile (PA) nanofibers have been shown to target and deliver drugs when administered via an intravenous (IV) injection. Subcutaneous administration can broaden the applicability of PA nanofibers in the medical field. The ability of PA nanofibers to be absorbed into systemic circulation after subcutaneous administration was investigated. Four PA molecules with different amino acid sequences were designed to understand the effect of nanofiber cohesion and charge on uptake. Solution small-angle X-ray scattering confirmed nanostructure morphology and provided characteristic lengths for co-assemblies. Circular dichroism and solution wide-angle X-ray scattering confirmed PA secondary structure and molecular order. PAs were co-assembled in a 95 %:5 % molar ratio of unlabeled PA to fluorescently labeled PA. Male and female Sprague Dawley rats were injected in the nape of the neck with PA co-assemblies. In vivo normalized abdominal fluorescence was measured 1-72 h after injection. PA nanofibers with a negative charge and low internal order showed the highest amount of systemic absorption at 1, 6, and 24 h. At 24 h after injection, white blood cell count decreased and glucose was elevated. Glucose began to decrease at 48 h. These data indicate that PA nanofibers can be absorbed into the systemic circulation after subcutaneous injection.
    MeSH term(s) Rats ; Animals ; Male ; Female ; Nanofibers/chemistry ; Rats, Sprague-Dawley ; Peptides/chemistry ; Injections, Subcutaneous ; Glucose
    Chemical Substances Peptides ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2023-11-18
    Publishing country Netherlands
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ZDB-ID 603079-8
    ISSN 1878-5905 ; 0142-9612
    ISSN (online) 1878-5905
    ISSN 0142-9612
    DOI 10.1016/j.biomaterials.2023.122401
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  10. Article ; Online: Quality of Life in Patients With Glioblastoma Treated With Tumor-Treating Fields-Reply.

    Stupp, Roger / Ram, Zvi

    JAMA

    2018  Volume 319, Issue 17, Page(s) 1823

    MeSH term(s) Brain Neoplasms ; Electric Stimulation Therapy ; Glioblastoma ; Humans ; Quality of Life
    Language English
    Publishing date 2018--01
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2018.1862
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.88: Show issues Location:
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