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  1. Article ; Online: Y

    Tai, Yuehui / Zhang, Yu / Sun, Jinlong / Liu, Fuyue / Tian, Haoran / Liu, Qifeng / Li, Caihong

    RSC advances

    2021  Volume 11, Issue 39, Page(s) 24044–24053

    Abstract: Endowing photocatalytic materials with a broader range of light responses is important for improving their performance and solar energy utilization. In this study, a simple sol-gel method was used to prepare ... ...

    Abstract Endowing photocatalytic materials with a broader range of light responses is important for improving their performance and solar energy utilization. In this study, a simple sol-gel method was used to prepare Yb
    Language English
    Publishing date 2021-07-07
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d1ra03066c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Y

    Zhao, Rui-Qiang / Wen, Yan / Gupta, Pranav / Lei, Zi-Ning / Cai, Chao-Yun / Liang, Gang / Yang, Dong-Hua / Chen, Zhe-Sheng / Xie, Yu-An

    Frontiers in pharmacology

    2019  Volume 9, Page(s) 1545

    Abstract: ... Y ...

    Abstract Multidrug resistance is reported to be related to the transmembrane transportation of chemotherapeutic drugs by adenosine triphosphate-binding cassette (ABC) transporters. ABC subfamily G member 2 (ABCG2) is a member of the ABC transporter superfamily proteins, which have been implicated as a key contributor to the development of multidrug resistance in cancers. A new epigallocatechin gallate derivative, Y
    Language English
    Publishing date 2019-01-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2018.01545
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Y

    Yu, Zhangsen / Xia, Yuanzhi / Xing, Jie / Li, Zihou / Zhen, Jianjun / Jin, Yinhua / Tian, Yuchen / Liu, Chuang / Jiang, Zhenqi / Li, Juan / Wu, Aiguo

    Nanoscale

    2018  Volume 10, Issue 36, Page(s) 17038–17052

    Abstract: Achieving efficient photodynamic therapy (PDT) in deeper biological tissue is still the biggest bottleneck that limits its widespread application in clinic. Although deeper biological tissue PDT could be realized through a combination of upconversion ... ...

    Abstract Achieving efficient photodynamic therapy (PDT) in deeper biological tissue is still the biggest bottleneck that limits its widespread application in clinic. Although deeper biological tissue PDT could be realized through a combination of upconversion nanoparticles with a photosensitizer, issues with particle-size-induced upconversion fluorescence (UF) reduction and the related in vivo toxicity still cannot be solved properly. In this study, we synthesized Y1Rs-ligand [Pro30, Nle31, Bpa32, Leu34]NPY(28-36) (NPY)-modified and photosensitizer MC540-loaded LiLuF4:Yb,Er@nLiGdF4@mSiO2 multifunctional nanocomposites (MNPs) with a core-multishell structure and ultrasmall size. Their in vitro and in vivo breast tumor targeting, trimodality imaging performance, PDT therapeutic efficacy, and acute toxicity were evaluated. Our results demonstrated that the core-multishell MNPs(MC540) could achieve excellent UF imaging, and that doping with Gd3+ and Lu3+ rare earth ions could enhance the MR and CT imaging performance. In addition, the mSiO2 shell provided a higher loading rate for the photosensitizer MC540, and the DSPE-PEG thin layer coating outside the MNPs(MC540) further improved the water solubility and biocompatibility, reducing the acute toxicity of the nanocomposites. Finally, the NPY modification enhanced the targetability of MNPs(MC540)/DSPE-PEG-NPY to breast tumors, improving the trimodality UF, CT, and MR imaging performance and PDT efficacy for Y1-receptor-overexpressed breast cancer. In general, our developed multifunctional nanocomposites can serve as a theranostic agent with low toxicity, providing great potential for their use in clinical breast cancer diagnosis and therapy.
    MeSH term(s) Animals ; Cell Line, Tumor ; Female ; Humans ; MCF-7 Cells ; Mice, Inbred BALB C ; Mice, Inbred ICR ; Nanocomposites/chemistry ; Nanoparticles/chemistry ; Neoplasms, Experimental/drug therapy ; Photochemotherapy ; Photosensitizing Agents/pharmacology ; Xenograft Model Antitumor Assays
    Chemical Substances Photosensitizing Agents
    Language English
    Publishing date 2018-04-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/c8nr02387e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Mechanical and chemical itch regulated by neuropeptide Y-Y

    Chen, Sihan / Chen, Junhui / Tang, Dan / Yin, Wen / Xu, Saihong / Gao, Po / Jiao, Yingfu / Yu, Weifeng

    Molecular pain

    2024  Volume 20, Page(s) 17448069241242982

    Abstract: ... insect biting. It has been reported that neuropeptide Y (NPY) neurons, a population of spinal inhibitory ...

    Abstract Itch is a somatosensory sensation to remove potential harmful stimulation with a scratching desire, which could be divided into mechanical and chemical itch according to diverse stimuli, such as wool fiber and insect biting. It has been reported that neuropeptide Y (NPY) neurons, a population of spinal inhibitory interneurons, could gate the transmission of mechanical itch, with no effect on chemical itch. In our study, we verified that chemogenetic activation of NPY neurons could inhibit the mechanical itch as well as the chemical itch, which also attenuated the alloknesis phenomenon in the chronic dry skin model. Afterwards, intrathecal administration of NPY1R agonist, [Leu
    MeSH term(s) Animals ; Neuropeptide Y ; Receptors, Neuropeptide Y ; Pruritus/chemically induced ; Signal Transduction ; Spinal Cord
    Chemical Substances Neuropeptide Y ; Receptors, Neuropeptide Y
    Language English
    Publishing date 2024-03-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2174252-2
    ISSN 1744-8069 ; 1744-8069
    ISSN (online) 1744-8069
    ISSN 1744-8069
    DOI 10.1177/17448069241242982
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Preparation of Y

    Ren, Yu / Zhao, Ziyao / Jiang, Wenwen / Zhang, Guangyu / Tan, Yuxin / Guan, Yongyin / Zhou, Long / Cui, Li / Choi, Sung Woong / Li, Mei-Xian

    Polymers

    2022  Volume 14, Issue 14

    Abstract: In this study, Y ...

    Abstract In this study, Y
    Language English
    Publishing date 2022-07-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym14142760
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Highly efficient upconversion luminescence in narrow-bandgap Y

    You, Wenwu / Zhang, Xiaomin / Yu, Ruoxi / Chen, Chao / Li, Mingxing / Pan, Gencai / Mao, Yanli

    Optics letters

    2024  Volume 49, Issue 7, Page(s) 1824–1827

    Abstract: ... we have discovered in this study that Y ...

    Abstract Lanthanide-doped upconversion (UC) materials have been extensively investigated for their unique capability to convert low-energy excitation into high-energy emission. Contrary to previous reports suggesting that efficient UC luminescence (UCL) is exclusively observed in materials with a wide bandgap, we have discovered in this study that Y
    Language English
    Publishing date 2024-04-01
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4794
    ISSN (online) 1539-4794
    DOI 10.1364/OL.519702
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  7. Article ; Online: Roles of Y-27632 on sheep sperm metabolism.

    Fu, Yu / Shen, Wenzheng / Bai, Haiyu / Zhang, Zhiyu / Cao, Zhikun / Liu, Zibo / Yang, Chao / Sun, Shixin / Wang, Lei / Ling, Yinghui / Zhang, Zijun / Cao, Hongguo

    Journal of animal science

    2024  Volume 102

    Abstract: To investigate the effect of Y-27632 on low-temperature metabolism of sheep sperm, different ... concentrations of Y-27632 were added to sheep semen at 4 °C in this experiment to detect indicators ... metabolomics. The results showed that the addition of 20 µM Y-27632 significantly increased sperm motility ...

    Abstract To investigate the effect of Y-27632 on low-temperature metabolism of sheep sperm, different concentrations of Y-27632 were added to sheep semen at 4 °C in this experiment to detect indicators such as sperm motility, plasma membrane, acrosome, antioxidant performance, mitochondrial membrane potential (MMP), and metabolomics. The results showed that the addition of 20 µM Y-27632 significantly increased sperm motility, plasma membrane integrity rate, acrosome integrity rate, antioxidant capacity, MMP level, significantly increased sperm adenosine triphosphate (ATP) and total cholesterol content, and significantly reduced sperm Ca2+ content. In metabolomics analysis, compared with the control group, the 20 µM Y-27632 group screened 20 differential metabolites, mainly involved in five metabolic pathways, with the most significant difference in Histidine metabolism (P = 0.001). The results confirmed that Y-27632 significantly improved the quality of sheep sperm preservation under low-temperature conditions.
    MeSH term(s) Male ; Animals ; Sheep ; Semen/metabolism ; Antioxidants/metabolism ; Sperm Motility ; Spermatozoa ; Semen Preservation/veterinary ; Cryopreservation/veterinary ; Amides ; Pyridines
    Chemical Substances Y 27632 (138381-45-0) ; Antioxidants ; Amides ; Pyridines
    Language English
    Publishing date 2024-01-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390959-1
    ISSN 1525-3163 ; 0021-8812
    ISSN (online) 1525-3163
    ISSN 0021-8812
    DOI 10.1093/jas/skae020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1312: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  8. Article ; Online: Structural and magnetic properties of Y

    Zhang, Yuanjing / Yang, Qinghui / Liu, Yingli / Hu, Aimin / Zhang, Ding / Li, Han / Yu, Jingyan / Huang, Jiantao / Lu, Yongcheng / Zhang, Lei / Xue, Qiang / Li, Yilei / Jin, Lichuan / Wen, Qiye / Zhang, Huaiwu

    Acta crystallographica Section B, Structural science, crystal engineering and materials

    2023  Volume 79, Issue Pt 2, Page(s) 157–163

    Abstract: ... applications. In this work, 200 nm Y ...

    Abstract Ultra-thin rare earth iron garnet (RIG) films with a narrow ferromagnetic resonance (FMR) line width and a low damping factor have attracted a great deal of attention for microwave and spintronic applications. In this work, 200 nm Y
    Language English
    Publishing date 2023-03-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2020841-8
    ISSN 2052-5206 ; 1600-5740 ; 1600-8650 ; 2052-5192
    ISSN (online) 2052-5206 ; 1600-5740 ; 1600-8650
    ISSN 2052-5192
    DOI 10.1107/S2052520623000483
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  9. Article ; Online: Polycrystalline Er-doped Y

    Yu, Zhimin / Yuan, Kang / Yang, Yang / Sun, Jiaming

    Nanoscale

    2022  Volume 14, Issue 29, Page(s) 10540–10548

    Abstract: Polycrystalline erbium-doped Y ...

    Abstract Polycrystalline erbium-doped Y
    Language English
    Publishing date 2022-07-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/d2nr03118c
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  10. Article ; Online: Reply to the Letter to the Editor From He Y et al.

    Okubo, Yu / Yatabe, Yasushi

    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

    2023  Volume 18, Issue 5, Page(s) e46–e48

    MeSH term(s) Male ; Humans ; Lung Neoplasms
    Language English
    Publishing date 2023-03-29
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2432037-7
    ISSN 1556-1380 ; 1556-0864
    ISSN (online) 1556-1380
    ISSN 1556-0864
    DOI 10.1016/j.jtho.2023.02.006
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6664: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 652: Show issues

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