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  1. Article ; Online: Gender effects in cancer treatment and outcome.

    Dutcher, Janice P

    British journal of haematology

    2021  Volume 194, Issue 2, Page(s) 229–230

    MeSH term(s) Humans ; Neoplasms/therapy ; Risk Factors ; Treatment Outcome
    Language English
    Publishing date 2021-06-17
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.17529
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: Renal cell carcinoma supplement

    Dutcher, Janice P.

    (Medical oncology ; 26, Suppl. 1)

    2009  

    Author's details guest ed.: Jan Dutcher
    Series title Medical oncology ; 26, Suppl. 1
    Collection
    Language English
    Size S37 S. : graph. Darst.
    Publisher Humana Press
    Publishing place Totowa, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT015864045
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Families with non-Hodgkin lymphoma and plasma cell dyscrasias in their pedigrees.

    Wiernik, Peter H / Dutcher, Janice P

    Journal of investigative medicine : the official publication of the American Federation for Clinical Research

    2023  Volume 72, Issue 1, Page(s) 26–31

    Abstract: Although reports of familial clustering of hematologic malignancies have appeared for decades, the cause(s) of this uncommon occurrence is still not completely understood. Most modern investigations, however, support a genetic rather than an ... ...

    Abstract Although reports of familial clustering of hematologic malignancies have appeared for decades, the cause(s) of this uncommon occurrence is still not completely understood. Most modern investigations, however, support a genetic rather than an environmental exposure as a cause of this observation. Most pedigrees of families with familial hematologic malignancies demonstrate age of onset anticipation, with the disease diagnosed at an earlier age in successive generations. The cause of this phenomenon is clear in some familial neurologic disorders (trinucleotide repeat expansion) but not at all clear in familial hematologic malignancies. In preparation for molecular studies of familial clustering of hematologic malignancies, we have collected pedigrees on 738 families and have previously demonstrated anticipation in those with familial plasma cell myeloma, chronic lymphocytic leukemia, Hodgkin lymphoma or non-Hodgkin lymphoma (NHL). Here we present data on 36 families with both plasma cell myeloma and NHL in their pedigrees and demonstrate strong evidence for anticipation in these families. We encourage all health care personnel to ask patients multiple times about family medical history and carefully take note of family histories from individuals with uncommon illnesses and to refer families with clustering of such illnesses for further investigation.
    MeSH term(s) Humans ; Multiple Myeloma/genetics ; Pedigree ; Lymphoma, Non-Hodgkin/genetics ; Lymphoma, Non-Hodgkin/epidemiology ; Paraproteinemias ; Hematologic Neoplasms
    Language English
    Publishing date 2023-11-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1217870-6
    ISSN 1708-8267 ; 0009-9279 ; 1081-5589
    ISSN (online) 1708-8267
    ISSN 0009-9279 ; 1081-5589
    DOI 10.1177/10815589231210516
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: "Pseudoprogression": more than semantics.

    Dutcher, Janice P

    Cancer immunology, immunotherapy : CII

    2018  Volume 67, Issue 9, Page(s) 1473–1474

    MeSH term(s) Carcinoma, Renal Cell/immunology ; Carcinoma, Renal Cell/therapy ; Disease Progression ; Humans ; Immunotherapy ; Kidney Neoplasms/immunology ; Kidney Neoplasms/therapy ; Prognosis ; Protein Kinase Inhibitors/therapeutic use
    Chemical Substances Protein Kinase Inhibitors
    Language English
    Publishing date 2018-07-18
    Publishing country Germany
    Document type Case Reports ; Letter
    ZDB-ID 195342-4
    ISSN 1432-0851 ; 0340-7004
    ISSN (online) 1432-0851
    ISSN 0340-7004
    DOI 10.1007/s00262-018-2208-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: High dose interleukin-2 in metastatic disease: renal cell carcinoma and melanoma

    Dutcher, Janice P.

    (Oncology ; 16,11, Suppl. 13)

    2002  

    Title variant High-dose interleukin-2 in metastatic disease: renal cell carcinoma and melanoma
    Author's details guest ed. Janice Dutcher
    Series title Oncology ; 16,11, Suppl. 13
    Collection
    Language English
    Size 20 S.
    Publisher PRR
    Publishing place Melville, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT013545543
    Database Catalogue ZB MED Medicine, Health

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  6. Article ; Online: Update on the biology and management of renal cell carcinoma.

    Dutcher, Janice P

    Journal of investigative medicine : the official publication of the American Federation for Clinical Research

    2018  Volume 67, Issue 1, Page(s) 1–10

    Abstract: Renal cell cancer (RCC) (epithelial carcinoma of the kidney) represents 2%-4% of newly diagnosed adult tumors. Over the past 2 decades, RCC has been better characterized clinically and molecularly. It is a heterogeneous disease, with multiple subtypes, ... ...

    Abstract Renal cell cancer (RCC) (epithelial carcinoma of the kidney) represents 2%-4% of newly diagnosed adult tumors. Over the past 2 decades, RCC has been better characterized clinically and molecularly. It is a heterogeneous disease, with multiple subtypes, each with characteristic histology, genetics, molecular profiles, and biologic behavior. Tremendous heterogeneity has been identified with many distinct subtypes characterized. There are clinical questions to be addressed at every stage of this disease, and new targets being identified for therapeutic development. The unique characteristics of the clinical presentations of RCC have led to both questions and opportunities for improvement in management. Advances in targeted drug development and understanding of immunologic control of RCC are leading to a number of new clinical trials and regimens for advanced disease, with the goal of achieving long-term disease-free survival, as has been achieved in a proportion of such patients historically. RCC management is a promising area of ongoing clinical investigation.
    MeSH term(s) Animals ; Carcinoma, Renal Cell/genetics ; Carcinoma, Renal Cell/pathology ; Carcinoma, Renal Cell/therapy ; Chemotherapy, Adjuvant ; Genetic Heterogeneity ; Humans ; Kidney Neoplasms/genetics ; Kidney Neoplasms/pathology ; Kidney Neoplasms/therapy ; Neoplasm Metastasis ; Risk Factors
    Language English
    Publishing date 2018-11-18
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1217870-6
    ISSN 1708-8267 ; 0009-9279 ; 1081-5589
    ISSN (online) 1708-8267
    ISSN 0009-9279 ; 1081-5589
    DOI 10.1136/jim-2018-000918
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Interleukin-2 Can Cure Kidney Cancer.

    Dutcher, Janice P / Wiernik, Peter H

    The oncologist

    2018  Volume 23, Issue 9, Page(s) e107

    MeSH term(s) Humans ; Interleukin-2/pharmacology ; Interleukin-2/therapeutic use ; Kidney Neoplasms/drug therapy ; Kidney Neoplasms/pathology
    Chemical Substances Interleukin-2
    Language English
    Publishing date 2018-08-13
    Publishing country United States
    Document type Letter
    ZDB-ID 1409038-7
    ISSN 1549-490X ; 1083-7159
    ISSN (online) 1549-490X
    ISSN 1083-7159
    DOI 10.1634/theoncologist.2018-0038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Modern transfusion therapy / 2

    Dutcher, Janice P.

    1990  

    Author's details ed. Janice P. Dutcher
    Collection Modern transfusion therapy
    Language English
    Size 339 S. : Ill., graph. Darst.
    Publisher CRC Pr
    Publishing place Boca Raton, Fla
    Publishing country United States
    Document type Book
    HBZ-ID HT003500532
    ISBN 0-8493-6248-2 ; 978-0-8493-6248-4
    Database Catalogue ZB MED Medicine, Health

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  9. Book: Modern transfusion therapy / 1

    Dutcher, Janice P.

    1990  

    Author's details ed. Janice P. Dutcher
    Collection Modern transfusion therapy
    Language English
    Size 293 S. : graph. Darst.
    Publisher CRC Pr
    Publishing place Boca Raton, Fla
    Publishing country United States
    Document type Book
    HBZ-ID HT003500527
    ISBN 0-8493-6247-4 ; 978-0-8493-6247-7
    Database Catalogue ZB MED Medicine, Health

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