LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 555

Search options

  1. Book: Biomarkers in oncology

    Lenz, Heinz-Josef

    prediction and prognosis

    2012  

    Author's details Heinz-Josef Lenz ed
    Keywords Cancer--Diagnosis ; Tumor markers--Diagnostic use.
    Language English
    Size XVI, 447 S. : Ill., graph. Darst., 24 cm
    Publisher Springer
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT017418891
    ISBN 978-1-4419-9754-8 ; 9781441997555 ; 1-4419-9754-7 ; 1441997555
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2012 A 4055 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Book: Irinotecan: a decade of difference

    Lenz, Heinz-Josef

    (Community oncology ; 4,5, Suppl. 2)

    2007  

    Author's details guest ed. Heinz-Josef Lenz
    Series title Community oncology ; 4,5, Suppl. 2
    Collection
    Language English
    Size 24 S. : graph. Darst.
    Publisher Elsevier
    Publishing place Huntington, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT015241575
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 6521 -4,5,Suppl.2- verfügbar in Königswinter Königswinter

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Book: KRAS mutation in metastatic colorectal cancer and its impact on the use of EGFR inhibitors

    Lenz, Heinz-Josef / Chu, Edward / Grothey, Axel

    (Clinical advances in hematology & oncology ; 6,12, Suppl. 21 : Clinical roundtable monograph)

    2008  

    Author's details moderator Heinz-Josef Lenz. Discussants Edward Chu ; Axel Grothey
    Series title Clinical advances in hematology & oncology ; 6,12, Suppl. 21 : Clinical roundtable monograph
    Collection
    Language English
    Size 13 S. : Ill., graph. Darst.
    Publisher Millennium Medical Publ
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT016467668
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 6505 -6,Suppl.21- verfügbar in Königswinter Königswinter

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Reduced Tumor Size of Untreated Papillary Thyroid Carcinoma After Immune Checkpoint Inhibitor-Induced Thyroiditis.

    Chen, Dennis H / Lenz, Heinz-Josef / Lechner, Melissa G / Angell, Trevor E

    AACE clinical case reports

    2023  Volume 9, Issue 5, Page(s) 162–165

    Abstract: Background/objective: Immune checkpoint inhibitors (CPIs) activate antitumoral immune responses and are used to treat multiple types of primary and metastatic malignancies. Thyroid dysfunction is a known immune-related adverse event of CPI therapy. ... ...

    Abstract Background/objective: Immune checkpoint inhibitors (CPIs) activate antitumoral immune responses and are used to treat multiple types of primary and metastatic malignancies. Thyroid dysfunction is a known immune-related adverse event of CPI therapy. There are few data on the effect of CPI and CPI-induced thyroiditis on primary papillary thyroid carcinoma (PTC). We present a patient who developed CPI-induced thyroiditis during treatment for a nonthyroid malignancy and subsequent regression of a coexisting untreated primary PTC.
    Case report: A 49-year-old man with metastatic colon adenocarcinoma was found to have a large right thyroid nodule with biopsy confirmation of PTC. He did not have compressive symptoms or evidence of metastatic PTC. Resection was not performed because of colon cancer therapy. Treatment with CPI (ezabenlimab, an anti-programmed cell death protein 1 antibody) was initiated for the treatment of colon cancer. Four months after the initiation of CPI therapy, testing showed thyroid-stimulating hormone and free thyroxine levels of 174.9 (0.3-4.0 mIU/L) and 0.67 (0.93-1.70 ng/dL), respectively, consistent with CPI-induced hypothyroidism. Levothyroxine therapy was initiated. Repeat imaging 3 months later demonstrated a decrease in the tumor size to 4.1 × 4.9 × 4.2 cm (calculated volume change, -8.3% from baseline). At the last imaging, 1 year after the onset of CPI-induced thyroiditis, the PTC continued to decrease in size and measured 2.9 × 3.9 × 3.2 cm (volume change, -60.7% from baseline).
    Discussion: CPI-induced thyroiditis suggests the development of an immune response against thyroid tissue and may reflect a similar increased immune response against PTC cells leading to tumor regression in this case.
    Conclusion: Further research to assess the immunologic mechanism underlying this association is warranted to potentially develop improved immunotherapy for PTC.
    Language English
    Publishing date 2023-06-03
    Publishing country United States
    Document type Case Reports
    ISSN 2376-0605
    ISSN (online) 2376-0605
    DOI 10.1016/j.aace.2023.05.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Book: Angiogenesis as a target in colorectal cancer therapy

    Ellis, Lee M. / Lenz, Heinz-Josef

    (Seminars in oncology ; 31,6, Suppl. 17)

    2004  

    Author's details Heinz-Josef Lenz, guest ed. Contrib. Lee M. Ellis
    Series title Seminars in oncology ; 31,6, Suppl. 17
    Collection
    Keywords Dickdarmkrebs ; Angiogenese
    Subject Gefäßentwicklung ; Colorektaler Krebs ; Colorectalcarcinom ; Kolorektales Karzinom ; Kolorektales Carcinom ; Dickdarmkarzinom
    Language English
    Size 28 S. : graph. Darst.
    Publisher Saunders
    Publishing place Philadelphia, PA
    Publishing country United States
    Document type Book
    HBZ-ID HT014303108
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 1348 -31,Suppl.17- not available for loan Zeitschriften-Lesesaal

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article: How we treat left-sided vs right-sided colon cancer.

    Hanna, Diana L / Lenz, Heinz-Josef

    Clinical advances in hematology & oncology : H&O

    2020  Volume 18, Issue 5, Page(s) 253–257

    MeSH term(s) Aged ; Antineoplastic Agents, Immunological/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Bevacizumab/therapeutic use ; Colon/drug effects ; Colon/pathology ; Colonic Neoplasms/diagnosis ; Colonic Neoplasms/genetics ; Colonic Neoplasms/pathology ; Colonic Neoplasms/therapy ; Female ; Fluorouracil/therapeutic use ; Humans ; Leucovorin/therapeutic use ; Male ; Middle Aged ; Mutation/drug effects ; Neoplasm Metastasis/diagnosis ; Neoplasm Metastasis/genetics ; Neoplasm Metastasis/pathology ; Neoplasm Metastasis/therapy ; Organoplatinum Compounds/therapeutic use
    Chemical Substances Antineoplastic Agents, Immunological ; Organoplatinum Compounds ; Bevacizumab (2S9ZZM9Q9V) ; Leucovorin (Q573I9DVLP) ; Fluorouracil (U3P01618RT)
    Language English
    Publishing date 2020-07-14
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2271951-9
    ISSN 1543-0790
    ISSN 1543-0790
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6505: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Microsatellite Stable Colorectal Liver Metastases-Understanding the Mechanisms of Immune Resistance.

    Gholami, Sepideh / Grothey, Axel / Lenz, Heinz-Josef

    JAMA network open

    2021  Volume 4, Issue 8, Page(s) e2119025

    MeSH term(s) Colorectal Neoplasms/genetics ; Humans ; Liver Neoplasms/genetics ; Microsatellite Repeats
    Language English
    Publishing date 2021-08-02
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2021.19025
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article ; Online: What Should We Do Better? Lessons from Negative Results of a Biomarker Validation Study.

    Battaglin, Francesca / Lenz, Heinz-Josef

    Journal of the National Cancer Institute

    2019  Volume 111, Issue 8, Page(s) 754–756

    MeSH term(s) Biomarkers ; Colonic Neoplasms ; Colorectal Neoplasms ; Humans ; Negative Results ; Oxaliplatin
    Chemical Substances Biomarkers ; Oxaliplatin (04ZR38536J)
    Language English
    Publishing date 2019-01-15
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2992-0
    ISSN 1460-2105 ; 0027-8874 ; 0198-0157
    ISSN (online) 1460-2105
    ISSN 0027-8874 ; 0198-0157
    DOI 10.1093/jnci/djy217
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.131: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: New perspectives for colorectal cancer.

    Puccini, Alberto / Lenz, Heinz-Josef

    Oncotarget

    2017  Volume 8, Issue 26, Page(s) 41782–41783

    Language English
    Publishing date 2017-05-20
    Publishing country United States
    Document type News
    ZDB-ID 2560162-3
    ISSN 1949-2553 ; 1949-2553
    ISSN (online) 1949-2553
    ISSN 1949-2553
    DOI 10.18632/oncotarget.18448
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: The Emergence of Baricitinib: A Story of Tortoises Versus Hares.

    Lenz, Heinz-Josef / Richardson, Peter / Stebbing, Justin

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2020  Volume 72, Issue 7, Page(s) 1251–1252

    MeSH term(s) Azetidines ; Coronavirus Infections ; Cytokines ; Humans ; Pandemics ; Pneumonia, Viral ; Purines ; Pyrazoles ; Sulfonamides
    Chemical Substances Azetidines ; Cytokines ; Purines ; Pyrazoles ; Sulfonamides ; baricitinib (ISP4442I3Y)
    Keywords covid19
    Language English
    Publishing date 2020-09-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciaa940
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1505: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 480: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top