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  1. Article: Management of Severe COVID-19 in Pregnancy.

    Abourida, Yassamine / Rebahi, Houssam / Oussayeh, Imane / Chichou, Hajar / Fakhir, Bouchra / Soummani, Abderraouf / Jalal, Hicham / Bennaoui, Fatiha / Slitine, Nadia El Idrissi / Maoulainine, Fadl Mrabih Rabou / El Adib, Ahmed Rhassane / Samkaoui, Mohamed Abdenacer

    Case reports in obstetrics and gynecology

    2020  Volume 2020, Page(s) 8852816

    Abstract: The scarcity of data concerning pregnant patients gravely infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) makes their management difficult, as most of the reported cases in the literature present mild pneumonia symptoms. The ... ...

    Abstract The scarcity of data concerning pregnant patients gravely infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) makes their management difficult, as most of the reported cases in the literature present mild pneumonia symptoms. The core problem is laying out evidence on coronavirus's implications on pregnancy and delivery, as well as vertical transmission and neonatal mortality. A healthy 30-year-old pregnant woman, gravida 6, para 4, at 31 weeks of gestation, presented severe pneumonia symptoms promptly complicated with premature rupture of membranes (PROM). A nasopharyngeal swab returned positive for SARS-CoV-2 using reverse transcription polymerase chain reactions (RT-PCR). The parturient underwent a cesarean delivery. This paper is an attempt to outline management of the critical condition of COVID-19 during pregnancy.
    Keywords covid19
    Language English
    Publishing date 2020-07-27
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2627654-9
    ISSN 2090-6692 ; 2090-6684
    ISSN (online) 2090-6692
    ISSN 2090-6684
    DOI 10.1155/2020/8852816
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: What Open-Lung Biopsy Teaches Us about ARDS in COVID-19 Patients: Mechanisms, Pathology, and Therapeutic Implications.

    Abourida, Yassamine / Rebahi, Houssam / Chichou, Hajar / Fenane, Hicham / Msougar, Yassine / Fakhri, Anas / Hazmiri, Fatima Ezzahra / Ismail, Ayman / Rais, Hanane / Soraa, Nabila / Samkaoui, Mohammed Abdenasser

    BioMed research international

    2020  Volume 2020, Page(s) 2909673

    Abstract: Difficulties have risen while managing Acute Respiratory Distress Syndrome (ARDS) caused by COVID-19, although it meets the Berlin definition. Severe hypoxemia with near-normal compliance was noted along with coagulopathy. Understanding the precise ... ...

    Abstract Difficulties have risen while managing Acute Respiratory Distress Syndrome (ARDS) caused by COVID-19, although it meets the Berlin definition. Severe hypoxemia with near-normal compliance was noted along with coagulopathy. Understanding the precise pathophysiology of this atypical ARDS will assist researchers and physicians in improving their therapeutic approach. Previous work is limited to postmortem studies, while our report addresses patients under protective lung mechanical ventilation. An open-lung minithoracotomy was performed in 3 patients who developed ARDS related to COVID-19 and were admitted to the intensive care unit to carry out a pathological and microbiological analysis on lung tissue biopsy. Diffused alveolar damage with hyaline membranes was found, as well as plurifocal fibrin microthrombi and vascular congestion in all patients' specimens. Microbiological cultures were negative, whereas qualitative Reversed Transcriptase Polymerase Chain Reaction (RT-PCR) detected SARS-CoV-2 in the pulmonary parenchyma and pleural fluid in two patients. COVID-19 causes progressive ARDS with onset of severe hypoxemia, underlying a dual mechanism: shunt effect through diffused alveolar damage and dead space effect through thrombotic injuries in microvascular beds. It seems reasonable to manage this ventilation-perfusion ratio mismatch using a high dose of anticoagulant combined with glucocorticoids.
    MeSH term(s) Aged ; Anticoagulants/therapeutic use ; Biopsy/methods ; COVID-19/drug therapy ; COVID-19/pathology ; COVID-19/virology ; Glucocorticoids/therapeutic use ; Humans ; Lung/drug effects ; Lung/pathology ; Lung/virology ; Male ; Respiration, Artificial ; Respiratory Distress Syndrome/drug therapy ; Respiratory Distress Syndrome/virology ; SARS-CoV-2/drug effects
    Chemical Substances Anticoagulants ; Glucocorticoids
    Language English
    Publishing date 2020-12-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2020/2909673
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Management of Severe COVID-19 in Pregnancy

    Yassamine Abourida / Houssam Rebahi / Imane Oussayeh / Hajar Chichou / Bouchra Fakhir / Abderraouf Soummani / Hicham Jalal / Fatiha Bennaoui / Nadia El Idrissi Slitine / Fadl Mrabih Rabou Maoulainine / Ahmed Rhassane El Adib / Mohamed Abdenacer Samkaoui

    Case Reports in Obstetrics and Gynecology, Vol

    2020  Volume 2020

    Abstract: The scarcity of data concerning pregnant patients gravely infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) makes their management difficult, as most of the reported cases in the literature present mild pneumonia symptoms. The ... ...

    Abstract The scarcity of data concerning pregnant patients gravely infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) makes their management difficult, as most of the reported cases in the literature present mild pneumonia symptoms. The core problem is laying out evidence on coronavirus’s implications on pregnancy and delivery, as well as vertical transmission and neonatal mortality. A healthy 30-year-old pregnant woman, gravida 6, para 4, at 31 weeks of gestation, presented severe pneumonia symptoms promptly complicated with premature rupture of membranes (PROM). A nasopharyngeal swab returned positive for SARS-CoV-2 using reverse transcription polymerase chain reactions (RT-PCR). The parturient underwent a cesarean delivery. This paper is an attempt to outline management of the critical condition of COVID-19 during pregnancy.
    Keywords Gynecology and obstetrics ; RG1-991 ; covid19
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Management of Severe COVID-19 in Pregnancy

    Abourida, Yassamine / Rebahi, Houssam / Oussayeh, Imane / Chichou, Hajar / Fakhir, Bouchra / Soummani, Abderraouf / Jalal, Hicham / Bennaoui, Fatiha / Slitine, Nadia El Idrissi / Maoulainine, Fadl Mrabih Rabou / El Adib, Ahmed Rhassane / Samkaoui, Mohamed Abdenacer

    Case reports in obstetrics and gynecology

    Abstract: The scarcity of data concerning pregnant patients gravely infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) makes their management difficult, as most of the reported cases in the literature present mild pneumonia symptoms The ... ...

    Abstract The scarcity of data concerning pregnant patients gravely infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) makes their management difficult, as most of the reported cases in the literature present mild pneumonia symptoms The core problem is laying out evidence on coronavirus's implications on pregnancy and delivery, as well as vertical transmission and neonatal mortality A healthy 30-year-old pregnant woman, gravida 6, para 4, at 31 weeks of gestation, presented severe pneumonia symptoms promptly complicated with premature rupture of membranes (PROM) A nasopharyngeal swab returned positive for SARS-CoV-2 using reverse transcription polymerase chain reactions (RT-PCR) The parturient underwent a cesarean delivery This paper is an attempt to outline management of the critical condition of COVID-19 during pregnancy
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #690173
    Database COVID19

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  5. Article: Management of Severe COVID-19 in Pregnancy

    Abourida, Yassamine

    Case reports in obstetrics and gynecology, 2020:8852816

    2020  

    Abstract: The scarcity of data concerning pregnant patients gravely infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) makes their management difficult, as most of the reported cases in the literature present mild pneumonia symptoms. The ... ...

    Abstract The scarcity of data concerning pregnant patients gravely infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) makes their management difficult, as most of the reported cases in the literature present mild pneumonia symptoms. The core problem is laying out evidence on coronavirus’s implications on pregnancy and delivery, as well as vertical transmission and neonatal mortality. A healthy 30-year-old pregnant woman, gravida 6, para 4, at 31 weeks of gestation, presented severe pneumonia symptoms promptly complicated with premature rupture of membranes (PROM). A nasopharyngeal swab returned positive for SARS-CoV-2 using reverse transcription polymerase chain reactions (RT-PCR). The parturient underwent a cesarean delivery. This paper is an attempt to outline management of the critical condition of COVID-19 during pregnancy.
    Keywords COVID-19
    Language English
    Document type Article
    Database Repository for Life Sciences

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