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  1. Article ; Online: Images in Vascular Medicine: Trapped thrombus underneath a recently placed inferior vena cava filter.

    Henkin, Stanislav / Rothstein, Eric S / Young, Michael N

    Vascular medicine (London, England)

    2020  Volume 26, Issue 3, Page(s) 346–347

    MeSH term(s) Cardiology ; Humans ; Pulmonary Embolism ; Thrombosis/diagnostic imaging ; Thrombosis/etiology ; Vena Cava Filters ; Vena Cava, Inferior/diagnostic imaging
    Language English
    Publishing date 2020-11-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 1311628-9
    ISSN 1477-0377 ; 1358-863X
    ISSN (online) 1477-0377
    ISSN 1358-863X
    DOI 10.1177/1358863X20967432
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4409: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Unrecognized perforation into the anterior interventricular vein complicating PCI for anterior STEMI: An unexpected detour.

    Rothstein, Eric S / Frampton, Jennifer / Devries, James T / Young, Michael N

    Clinical case reports

    2021  Volume 9, Issue 5, Page(s) e04055

    Abstract: Large iatrogenic coronary artery perforations require rapid management; however, operators must be able to recognize guidewire perforation into cardiac veins in order to avoid causing further complications with standard salvage strategies. ...

    Abstract Large iatrogenic coronary artery perforations require rapid management; however, operators must be able to recognize guidewire perforation into cardiac veins in order to avoid causing further complications with standard salvage strategies.
    Language English
    Publishing date 2021-05-05
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.4055
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Management of a patient presenting with anterior STEMI with concomitant COVID-19 infection early in the course of the U.S. pandemic.

    Rothstein, Eric S / Welch, Terrence D / Andrus, Bruce W / Jayne, John E

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2020  Volume 97, Issue 3, Page(s) E333–E338

    Abstract: The coronavirus disease-2019 (COVID-19) is a viral illness with heterogenous clinical manifestations, ranging from mild symptoms to severe acute respiratory distress syndrome and shock caused by the severe acute respiratory syndrome coronavirus-2. The ... ...

    Abstract The coronavirus disease-2019 (COVID-19) is a viral illness with heterogenous clinical manifestations, ranging from mild symptoms to severe acute respiratory distress syndrome and shock caused by the severe acute respiratory syndrome coronavirus-2. The global healthcare community is rapidly learning more about the effects of COVID-19 on the cardiovascular system, as well as the strategies for management of infected patients with cardiovascular disease. There is minimal literature available surrounding the relationship between COVID-19 infection and acute coronary syndrome. We describe the case of a woman who presented with an acute anterior ST-elevation myocardial infarction managed by primary percutaneous coronary intervention, who subsequently developed severe COVID-19 infection and ultimately succumbed to multisystem organ failure.
    MeSH term(s) Aged ; COVID-19/complications ; COVID-19/diagnosis ; COVID-19/therapy ; Delayed Diagnosis ; Fatal Outcome ; Female ; Humans ; Percutaneous Coronary Intervention ; ST Elevation Myocardial Infarction/diagnosis ; ST Elevation Myocardial Infarction/therapy ; ST Elevation Myocardial Infarction/virology ; Vermont
    Keywords covid19
    Language English
    Publishing date 2020-05-29
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.28967
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1226: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Mediation of antitumor activity by AZD4820 oncolytic vaccinia virus encoding IL-12.

    Kurokawa, Cheyne / Agrawal, Sonia / Mitra, Abhisek / Galvani, Elena / Burke, Shannon / Varshine, Ankita / Rothstein, Raymond / Schifferli, Kevin / Monks, Noel R / Foloppe, Johann / Silvestre, Nathalie / Quemeneur, Eric / Demeusoit, Christelle / Kleinpeter, Patricia / Sapra, Puja / Barrett, Carl / Hammond, Scott A / Kelly, Elizabeth J / Laliberte, Jason /
    Durham, Nicholas M / Oberst, Michael / Broggi, Maria A S

    Molecular therapy. Oncology

    2024  Volume 32, Issue 1, Page(s) 200758

    Abstract: Oncolytic viruses are engineered to selectively kill tumor cells and have demonstrated promising results in early-phase clinical trials. To further modulate the innate and adaptive immune system, we generated AZD4820, a vaccinia virus engineered to ... ...

    Abstract Oncolytic viruses are engineered to selectively kill tumor cells and have demonstrated promising results in early-phase clinical trials. To further modulate the innate and adaptive immune system, we generated AZD4820, a vaccinia virus engineered to express interleukin-12 (IL-12), a potent cytokine involved in the activation of natural killer (NK) and T cells and the reprogramming of the tumor immune microenvironment. Testing in cultured human tumor cell lines demonstrated broad
    Language English
    Publishing date 2024-01-10
    Publishing country United States
    Document type Journal Article
    ISSN 2950-3299
    ISSN 2950-3299
    DOI 10.1016/j.omton.2023.200758
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Unrecognized perforation into the anterior interventricular vein complicating PCI for anterior STEMI

    Eric S. Rothstein / Jennifer Frampton / James T. Devries / Michael N. Young

    Clinical Case Reports, Vol 9, Iss 5, Pp n/a-n/a (2021)

    An unexpected detour

    2021  

    Abstract: Abstract Large iatrogenic coronary artery perforations require rapid management; however, operators must be able to recognize guidewire perforation into cardiac veins in order to avoid causing further complications with standard salvage strategies. ...

    Abstract Abstract Large iatrogenic coronary artery perforations require rapid management; however, operators must be able to recognize guidewire perforation into cardiac veins in order to avoid causing further complications with standard salvage strategies.
    Keywords complication ; coronary perforation ; fistula ; myocardial infarction ; Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2021-05-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

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  6. Article ; Online: MiXcan: a framework for cell-type-aware transcriptome-wide association studies with an application to breast cancer.

    Song, Xiaoyu / Ji, Jiayi / Rothstein, Joseph H / Alexeeff, Stacey E / Sakoda, Lori C / Sistig, Adriana / Achacoso, Ninah / Jorgenson, Eric / Whittemore, Alice S / Klein, Robert J / Habel, Laurel A / Wang, Pei / Sieh, Weiva

    Nature communications

    2023  Volume 14, Issue 1, Page(s) 377

    Abstract: Human bulk tissue samples comprise multiple cell types with diverse roles in disease etiology. Conventional transcriptome-wide association study approaches predict genetically regulated gene expression at the tissue level, without considering cell-type ... ...

    Abstract Human bulk tissue samples comprise multiple cell types with diverse roles in disease etiology. Conventional transcriptome-wide association study approaches predict genetically regulated gene expression at the tissue level, without considering cell-type heterogeneity, and test associations of predicted tissue-level expression with disease. Here we develop MiXcan, a cell-type-aware transcriptome-wide association study approach that predicts cell-type-level expression, identifies disease-associated genes via combination of cell-type-level association signals for multiple cell types, and provides insight into the disease-critical cell type. As a proof of concept, we conducted cell-type-aware analyses of breast cancer in 58,648 women and identified 12 transcriptome-wide significant genes using MiXcan compared with only eight genes using conventional approaches. Importantly, MiXcan identified genes with distinct associations in mammary epithelial versus stromal cells, including three new breast cancer susceptibility genes. These findings demonstrate that cell-type-aware transcriptome-wide analyses can reveal new insights into the genetic and cellular etiology of breast cancer and other diseases.
    MeSH term(s) Female ; Humans ; Transcriptome ; Breast Neoplasms/genetics ; Gene Expression Profiling ; Breast/metabolism ; Genome-Wide Association Study ; Genetic Predisposition to Disease ; Polymorphism, Single Nucleotide
    Language English
    Publishing date 2023-01-23
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-35888-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: MiXcan

    Xiaoyu Song / Jiayi Ji / Joseph H. Rothstein / Stacey E. Alexeeff / Lori C. Sakoda / Adriana Sistig / Ninah Achacoso / Eric Jorgenson / Alice S. Whittemore / Robert J. Klein / Laurel A. Habel / Pei Wang / Weiva Sieh

    Nature Communications, Vol 14, Iss 1, Pp 1-

    a framework for cell-type-aware transcriptome-wide association studies with an application to breast cancer

    2023  Volume 15

    Abstract: Conventional transcriptome-wide association study (TWAS) approaches predict genetically regulated gene expression at the tissue level. Here, the authors develop a framework for cell-type-aware TWAS that predicts cell-type level expression from genotype ... ...

    Abstract Conventional transcriptome-wide association study (TWAS) approaches predict genetically regulated gene expression at the tissue level. Here, the authors develop a framework for cell-type-aware TWAS that predicts cell-type level expression from genotype data and identifies disease-associated genes with cell-type-specific effects.
    Keywords Science ; Q
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

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  8. Article ; Online: Management of a patient presenting with anterior STEMI with concomitant COVID ‐19 infection early in the course of the U.S. pandemic

    Rothstein, Eric S. / Welch, Terrence D. / Andrus, Bruce W. / Jayne, John E.

    Catheterization and Cardiovascular Interventions ; ISSN 1522-1946 1522-726X

    2020  

    Keywords Radiology Nuclear Medicine and imaging ; Cardiology and Cardiovascular Medicine ; General Medicine ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1002/ccd.28967
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Reply to the Editor- Leftward on left anterior oblique is not always septal!

    Iribarne, Alexander / Sangha, Rajbir S / Bostock, Ian C / Rothstein, Eric S / McCullough, Jock N

    HeartRhythm case reports

    2018  Volume 4, Issue 12, Page(s) 605

    Language English
    Publishing date 2018-09-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2834871-0
    ISSN 2214-0271
    ISSN 2214-0271
    DOI 10.1016/j.hrcr.2018.08.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Right ventricular lead perforation through the septum, left ventricle, and pleura, managed by an open surgical approach.

    Iribarne, Alexander / Sangha, Rajbir S / Bostock, Ian C / Rothstein, Eric S / McCullough, Jock N

    HeartRhythm case reports

    2018  Volume 4, Issue 9, Page(s) 397–400

    Language English
    Publishing date 2018-05-23
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834871-0
    ISSN 2214-0271
    ISSN 2214-0271
    DOI 10.1016/j.hrcr.2018.05.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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