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  1. Article ; Online: Tiotropium is superior to salmeterol in reducing frequency of exacerbations: but the effect of adding tiotropium to the combination of inhaled corticosteroid and long-acting β(2)-agonist remains unclear.

    Hodder, Rick

    Evidence-based medicine

    2012  Volume 17, Issue 3, Page(s) 93–95

    Language English
    Publishing date 2012-06
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 1324346-9
    ISSN 1473-6810 ; 1356-5524
    ISSN (online) 1473-6810
    ISSN 1356-5524
    DOI 10.1136/ebmed.2011.100206
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4793: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Critical care in the ED: potentially fatal asthma and acute lung injury syndrome.

    Hodder, Rick

    Open access emergency medicine : OAEM

    2012  Volume 4, Page(s) 53–68

    Abstract: Emergency department clinicians are frequently called upon to assess, diagnose, and stabilize patients who present with acute respiratory failure. This review describes a rapid initial approach to acute respiratory failure in adults, illustrated by two ... ...

    Abstract Emergency department clinicians are frequently called upon to assess, diagnose, and stabilize patients who present with acute respiratory failure. This review describes a rapid initial approach to acute respiratory failure in adults, illustrated by two common examples: (1) an airway disease - acute potentially fatal asthma, and (2) a pulmonary parenchymal disease - acute lung injury/acute respiratory distress syndrome. As such patients are usually admitted to hospital, discussion will be focused on those initial management aspects most relevant to the emergency department clinician.
    Language English
    Publishing date 2012-08-30
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2520704-0
    ISSN 1179-1500
    ISSN 1179-1500
    DOI 10.2147/OAEM.S30998
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: 3D printing of rock analogues in sand

    Hodder Kevin / Ishutov Sergey / Sanchez Angel / Zambrano Gonzalo / Chalaturnyk Rick

    E3S Web of Conferences, Vol 205, p

    a tool for design and repeatable testing of geomechanical and transport properties

    2020  Volume 04014

    Abstract: Natural rocks can be heterogeneous due to complex diagenetic processes that affect mineralogy and pore architecture. Correlation of geomechanical and transport properties of rocks in three dimensions can lead to large variances in data when tested ... ...

    Abstract Natural rocks can be heterogeneous due to complex diagenetic processes that affect mineralogy and pore architecture. Correlation of geomechanical and transport properties of rocks in three dimensions can lead to large variances in data when tested experimentally. 3D-printing of rock analogues in sand is a promising alternative for experimental testing that can be used to calibrate variables during geotechnical testing. While 3D-printed sand is a homogeneous material, the parameters for creating grain packing and pore infill can be tuned to mimic specific geomechanical and transport properties. Initially, 3D-printed specimens have a low density due to a loose distribution of grains. Herein, we present our efforts at increasing the density through incorporating a roller in the printing process to compact individual layers. We also propose introduction of a more heterogeneous sand mixture that encompasses a wide range of grain-size distributions. Lastly, a discussion between binder saturation (that infills the pore space) of 3D-printed specimens and the axial strength, dimensional control, and porosity is described within. 3D printing of rock analogues is critical in pursuing rigorous destructive tests required for geotechnical and geological engineering because it can provide repeatable, controlled data on rock properties.
    Keywords Environmental sciences ; GE1-350
    Subject code 670
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: The paradox of adult asthma control: "who's in control anyway?".

    Hodder, Rick

    Canadian respiratory journal

    2007  Volume 14, Issue 4, Page(s) 229–234

    Abstract: Surveys of Canadian patients with asthma and their physicians consistently report satisfaction with asthma management; however, when objective indicators are used, these same surveys also observe very poor levels of asthma control. The reasons for this ... ...

    Abstract Surveys of Canadian patients with asthma and their physicians consistently report satisfaction with asthma management; however, when objective indicators are used, these same surveys also observe very poor levels of asthma control. The reasons for this apparent discrepancy, with an emphasis on the factors influencing adherence to therapy, are explored in the present review. Clues to the identification of patients at risk of dying from asthma and an approach to difficult asthma are discussed.
    MeSH term(s) Adult ; Asthma/prevention & control ; Asthma/psychology ; Humans ; Patient Compliance ; Patient Satisfaction ; Treatment Outcome
    Language English
    Publishing date 2007-05
    Publishing country Egypt
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1213103-9
    ISSN 1916-7245 ; 1198-2241
    ISSN (online) 1916-7245
    ISSN 1198-2241
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4140: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Book: Long-term oxygen therapy

    Dal Negro, Roberto / Hodder, Rick

    new insights and perspectives

    2012  

    Author's details Roberto Walter Dal Negro, Richard Hodder, editors ; forewords by Marc Miravitlles and Dario Olivieri
    MeSH term(s) Oxygen Inhalation Therapy ; Hypoxia/therapy ; Long-Term Care ; Pulmonary Disease, Chronic Obstructive/therapy
    Language English
    Size xv, 235 p. :, ill.
    Publisher Springer
    Publishing place Milan
    Document type Book
    ISBN 9788847025790 ; 9788847025806 ; 8847025796 ; 884702580X
    Database Catalogue of the US National Library of Medicine (NLM)

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  6. Article ; Online: Inhaler devices for patients with COPD.

    Fink, James B / Colice, Gene L / Hodder, Rick

    COPD

    2013  Volume 10, Issue 4, Page(s) 523–535

    Abstract: Chronic obstructive pulmonary disease (COPD) continues to be associated with increased morbidity and mortality risk in spite of updated guidelines and a better understanding of this condition. Progressive airflow limitation and resultant hyperinflation- ... ...

    Abstract Chronic obstructive pulmonary disease (COPD) continues to be associated with increased morbidity and mortality risk in spite of updated guidelines and a better understanding of this condition. Progressive airflow limitation and resultant hyperinflation-the respiratory hallmarks of this complex and often under-diagnosed disease-can be treated with pharmacotherapies emitted via nebulizers, pressurized metered-dose inhalers, dry powder inhalers, or a Soft Mist inhaler. Pharmaceutical company proprietary issues, technological innovations, and societal pressure have expanded the list of available inhalers, with a limited range of medications available for any one device. Each device has different operating and maintenance instructions, and successful use of a given drug/device combination requires that patients understand, maintain, and use each of their devices properly in order to ensure consistent and optimal pulmonary drug delivery. Clinicians are faced with a range of physical and psychosocial issues unique to each patient with COPD that must be overcome in order to match a suitable inhaler to the individual. Improved drug delivery afforded by next-generation inhalers, coupled with an awareness of device-specific and patient-specific variables affecting inhaler use, may improve clinical outcomes in the treatment of COPD.
    MeSH term(s) Adrenergic beta-Agonists/administration & dosage ; Bronchodilator Agents/administration & dosage ; Cholinergic Antagonists/administration & dosage ; Dry Powder Inhalers ; Humans ; Metered Dose Inhalers ; Nebulizers and Vaporizers ; Patient Preference ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Time Factors
    Chemical Substances Adrenergic beta-Agonists ; Bronchodilator Agents ; Cholinergic Antagonists
    Language English
    Publishing date 2013-08
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2171107-0
    ISSN 1541-2563 ; 1541-2555
    ISSN (online) 1541-2563
    ISSN 1541-2555
    DOI 10.3109/15412555.2012.761960
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5990: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Canadian Adult Asthma Update 2008 key messages: a focus on translating knowledge into action in primary care.

    McIvor, Andrew / Hodder, Rick

    Canadian respiratory journal

    2008  Volume 15, Issue 3, Page(s) 121–122

    MeSH term(s) Asthma/diagnosis ; Asthma/prevention & control ; Asthma/therapy ; Canada ; Disease Management ; Guideline Adherence ; Hospitalization/statistics & numerical data ; Humans ; Information Dissemination ; Practice Guidelines as Topic ; Primary Health Care
    Language English
    Publishing date 2008-05-14
    Publishing country Egypt
    Document type Editorial
    ZDB-ID 1213103-9
    ISSN 1916-7245 ; 1198-2241
    ISSN (online) 1916-7245
    ISSN 1198-2241
    DOI 10.1155/2008/317302
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4140: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Practical aspects of inhaler use in the management of chronic obstructive pulmonary disease in the primary care setting.

    Yawn, Barbara P / Colice, Gene L / Hodder, Rick

    International journal of chronic obstructive pulmonary disease

    2012  Volume 7, Page(s) 495–502

    Abstract: Sustained bronchodilation using inhaled medications in moderate to severe chronic obstructive pulmonary disease (COPD) grades 2 and 3 (Global Initiative for Chronic Obstructive Lung Disease guidelines) has been shown to have clinical benefits on long- ... ...

    Abstract Sustained bronchodilation using inhaled medications in moderate to severe chronic obstructive pulmonary disease (COPD) grades 2 and 3 (Global Initiative for Chronic Obstructive Lung Disease guidelines) has been shown to have clinical benefits on long-term symptom control and quality of life, with possible additional benefits on disease progression and longevity. Aggressive diagnosis and treatment of symptomatic COPD is an integral and pivotal part of COPD management, which usually begins with primary care physicians. The current standard of care involves the use of one or more inhaled bronchodilators, and depending on COPD severity and phenotype, inhaled corticosteroids. There is a wide range of inhaler devices available for delivery of inhaled medications, but suboptimal inhaler use is a common problem that can limit the clinical effectiveness of inhaled therapies in the real-world setting. Patients' comorbidities, other physical or mental limitations, and the level of inhaler technique instruction may limit proper inhaler use. This paper presents information that can overcome barriers to proper inhaler use, including issues in device selection, steps in correct technique for various inhaler devices, and suggestions for assessing and monitoring inhaler techniques. Ensuring proper inhaler technique can maximize drug effectiveness and aid clinical management at all grades of COPD.
    MeSH term(s) Bronchodilator Agents/therapeutic use ; Humans ; Nebulizers and Vaporizers ; Patient Education as Topic ; Primary Health Care ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Self Care/standards
    Chemical Substances Bronchodilator Agents
    Language English
    Publishing date 2012-07-25
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2212419-6
    ISSN 1178-2005 ; 1176-9106
    ISSN (online) 1178-2005
    ISSN 1176-9106
    DOI 10.2147/COPD.S32674
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Operationalising the concept of ecosystem collapse for conservation practice

    Newton, Adrian C. / Britton, Robert / Davies, Kimberley / Diaz, Anita / Franklin, Daniel J. / Herbert, Roger J.H. / Hill, Ross A. / Hodder, Kathy / Jones, Georgia / Korstjens, Amanda H. / Lamb, Annesia / Olley, Jack / Pinder, Adrian C. / Roberts, Catherine Gutmann / Stafford, Rick

    Biological conservation. 2021 Dec., v. 264

    2021  

    Abstract: Concern is growing about ecosystem collapse, namely the abrupt decline or loss of an ecosystem resulting from human activities. While efforts to assess the risk of ecosystem collapse have developed at large spatial scales, less attention has been given ... ...

    Abstract Concern is growing about ecosystem collapse, namely the abrupt decline or loss of an ecosystem resulting from human activities. While efforts to assess the risk of ecosystem collapse have developed at large spatial scales, less attention has been given to the local scales at which conservation management decisions are typically made. Development of appropriate management responses to ecosystem collapse has been limited by uncertainty regarding how collapse may best be identified, together with its underlying causes. Here we operationalise ecosystem collapse for conservation practice by providing a robust definition of collapse, in a form that is relevant to the scale of conservation decision-making. We provide an overview of different causes of collapse, and then explore the implications of this understanding for conservation practice, by examining potential management responses. This is achieved through development of a decision tree, which we illustrate through a series of case studies. We also explore the role of indicators for the early detection of collapse and for monitoring the effectiveness of management responses. Ecosystem collapse represents a significant challenge to conservation practice, as abrupt changes in ecosystem structure, function and composition can occur with little warning, leading to profound impacts on both biodiversity and human society. The risks of ecosystem collapse are likely to increase in future, as multiple forms of environmental change continue to intensify. We suggest that selection of management responses should be based on an understanding of the causal mechanisms responsible for collapse, which can be identified through appropriate monitoring and research activities.
    Keywords biodiversity ; conservation practices ; decision making ; decision support systems ; ecosystems ; humans ; risk assessment ; society ; uncertainty
    Language English
    Dates of publication 2021-12
    Publishing place Elsevier Ltd
    Document type Article
    ISSN 0006-3207
    DOI 10.1016/j.biocon.2021.109366
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Lack of paradoxical bronchoconstriction after administration of tiotropium via Respimat® Soft Mist™ Inhaler in COPD.

    Hodder, Rick / Pavia, Demetri / Lee, Angela / Bateman, Eric

    International journal of chronic obstructive pulmonary disease

    2011  Volume 6, Page(s) 245–251

    Abstract: Bronchoconstriction has been reported in asthma and chronic obstructive pulmonary disease (COPD) patients after administration of some aqueous inhalation solutions. We investigated the incidence of this event during long-term clinical trials of ... ...

    Abstract Bronchoconstriction has been reported in asthma and chronic obstructive pulmonary disease (COPD) patients after administration of some aqueous inhalation solutions. We investigated the incidence of this event during long-term clinical trials of tiotropium delivered via Respimat(®) Soft Mist™ Inhaler (SMI). We retrospectively analyzed pooled data from two identical Phase III clinical trials, in which 1990 patients with COPD received 48 weeks' treatment with once-daily tiotropium (5 or 10 μg) or placebo inhaled via Respimat(®) SMI. We recorded the incidence of bronchospasm and of a range of respiratory events that could suggest bronchoconstriction during the first 30 minutes after inhalation of study treatment on each of the eight test days. No patients reported bronchospasm. Six patients (0.3%) reported a combination of at least two events suggestive of bronchoconstriction, and 21 (1.1%) reported either rescue medication use or a respiratory adverse event. Asymptomatic falls in forced expiratory volume in one second (FEV(1)) of ≥15% were recorded on all test days, with no change in incidence over time, and affected 8.2% of those in the tiotropium groups and 14.5% of those on placebo. In COPD patients receiving long-term treatment with tiotropium 5 or 10 μg via Respimat(®) SMI, no bronchospasm was recorded, and the number of events possibly indicative of paradoxical bronchoconstriction was very low.
    MeSH term(s) Administration, Inhalation ; Aged ; Bronchial Spasm/chemically induced ; Bronchial Spasm/physiopathology ; Bronchoconstriction/drug effects ; Bronchodilator Agents/administration & dosage ; Bronchodilator Agents/adverse effects ; Cholinergic Antagonists/administration & dosage ; Cholinergic Antagonists/adverse effects ; Clinical Trials, Phase III as Topic ; Female ; Forced Expiratory Volume/drug effects ; Humans ; Logistic Models ; Lung/drug effects ; Lung/physiopathology ; Male ; Middle Aged ; Multicenter Studies as Topic ; Nebulizers and Vaporizers ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Randomized Controlled Trials as Topic ; Retrospective Studies ; Risk Assessment ; Scopolamine Derivatives/administration & dosage ; Scopolamine Derivatives/adverse effects ; Tiotropium Bromide ; Treatment Outcome ; Vital Capacity/drug effects
    Chemical Substances Bronchodilator Agents ; Cholinergic Antagonists ; Scopolamine Derivatives ; Tiotropium Bromide (XX112XZP0J)
    Language English
    Publishing date 2011-04-26
    Publishing country New Zealand
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2212419-6
    ISSN 1178-2005 ; 1176-9106
    ISSN (online) 1178-2005
    ISSN 1176-9106
    DOI 10.2147/COPD.S16094
    Database MEDical Literature Analysis and Retrieval System OnLINE

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