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  1. Article ; Online: Response to Letter to the Editor from Jagannath and Mayilvaganan: "Is Multifocality a Predictor of Poor Outcome in Childhood and Adolescent Papillary Thyroid Carcinoma?"

    Scholfield, Daniel W / Lopez, Joseph / Eagan, Alana / Antal, Zoltan / Tuttle, R Michael / Ghossein, Ronald / LaQuaglia, Michael / Shaha, Ashok R / Shah, Jatin P / Wong, Richard J / Patel, Snehal G / Ganly, Ian

    The Journal of clinical endocrinology and metabolism

    2024  

    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3029-6
    ISSN 1945-7197 ; 0021-972X
    ISSN (online) 1945-7197
    ISSN 0021-972X
    DOI 10.1210/clinem/dgae118
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Atypical Presentation of Halo Nevus over Eyelid with Poliosis: A Dermatoscopic Perspective.

    Shah, Aishni J / Polra, Rutoo V / Prajapati, Kalpesh M / Nair, Pragya Ashok

    International journal of trichology

    2022  Volume 14, Issue 2, Page(s) 68–70

    Abstract: Halo nevus (HN) is benign skin condition with a central melanocytic nevus, surrounded by an area or halo of depigmentation. It is the result of immunological response of the body toward the nevus, which destroys the melanocytes in surrounding skin, ... ...

    Abstract Halo nevus (HN) is benign skin condition with a central melanocytic nevus, surrounded by an area or halo of depigmentation. It is the result of immunological response of the body toward the nevus, which destroys the melanocytes in surrounding skin, leading to the depigmented halo. An increased frequency of HN in patients with vitiligo is observed. It is more commonly seen in children or young adults of either sex, particularly on the trunk, less commonly on the face, neck, and limbs. We present a rare case of HN which was present on the lower eyelid associated with poliosis, diagnosed with dermatoscopy.
    Language English
    Publishing date 2022-04-04
    Publishing country India
    Document type Case Reports
    ZDB-ID 2570982-3
    ISSN 0974-9241 ; 0974-7753
    ISSN (online) 0974-9241
    ISSN 0974-7753
    DOI 10.4103/ijt.ijt_150_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Time to reposition sulfonylureas in type 2 diabetes management in Indian context: A pragmatic practical approach.

    Das, Ashok Kumar / Saboo, Banshi / Chawla, Rajeev / Aravind, S R / Rajput, Rajesh / Singh, Awadhesh K / Mukherjee, J J / Jhingan, Ashok / Shah, Parag / Deshmukh, Vaishali / Kale, Shailaja / Jaggi, Shalini / Sridhar, G R / Dhediya, Rajnish / Gaurav, Kumar

    International journal of diabetes in developing countries

    2023  , Page(s) 1–19

    Abstract: Sulfonylureas (SU) continue to be a vital therapeutic category of oral hypoglycemic agents (OHAs) for the management of type 2 diabetes mellitus (T2DM). Physicians consider modern SU (gliclazide and glimepiride) as "safe and smart" choices for T2DM ... ...

    Abstract Sulfonylureas (SU) continue to be a vital therapeutic category of oral hypoglycemic agents (OHAs) for the management of type 2 diabetes mellitus (T2DM). Physicians consider modern SU (gliclazide and glimepiride) as "safe and smart" choices for T2DM management. The presence of multiple international guidelines and scarcity of a national guideline may contribute to the challenges faced by few physicians in choosing the right therapeutic strategy. The role of SU in diabetes management is explicit, and the present consensus aims to emphasize the benefits and reposition SU in India. This pragmatic, practical approach aims to define expert recommendations for the physicians to improve caregivers' knowledge of the management of T2DM, leading to superior patient outcomes.
    Language English
    Publishing date 2023-04-19
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 2263351-0
    ISSN 1998-3832 ; 0973-3930
    ISSN (online) 1998-3832
    ISSN 0973-3930
    DOI 10.1007/s13410-023-01192-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Hospital volume as a predictor of outcomes following pediatric thyroidectomy.

    Yu, Victor J / Sasson, Daniel Cyrus / Scholfield, Daniel / Woods, Robbie / Wong, Richard / Shaha, Ashok / Shah, Jatin / Ganly, Ian / Lopez, Joseph

    Journal of surgical oncology

    2023  Volume 128, Issue 1, Page(s) 16–22

    Abstract: Background: Pediatric thyroidectomy (PT) is an uncommon procedure with a risk of significant morbidity. This study utilizes a national database to identify factors associated with short-term (30-day) post-thyroidectomy complications in children with ... ...

    Abstract Background: Pediatric thyroidectomy (PT) is an uncommon procedure with a risk of significant morbidity. This study utilizes a national database to identify factors associated with short-term (30-day) post-thyroidectomy complications in children with thyroid cancer.
    Methods: The 2016 and 2012 Kids' Inpatient Databases (KID) were used in this study. All children with thyroid cancer undergoing thyroidectomy were included. Complications were categorized into endocrine, nervous, pulmonary, and other. Hospital volume was stratified into high-volume (performing the top 10% of total cases, HVC) or non-high-volume centers (NHVC). Risk factors were analyzed using univariable and multivariable statistical tests.
    Results: Six hundred and sixty-three patients with an average age of 15.93 years met inclusion criteria. Most patients were seen in an NHVC (90.0%) and 37.3% of thyroidectomies were performed with neck dissections. The incidence of any complication was 32.1%. Endocrine complications were the most frequent (32.7%). Independent predictors of any or only endocrine complications were age (odds ratio [OR] = 0.927, p = 0.002, any; OR = 0.926, p = 0.003, endocrine) or concurrent neck dissection (OR = 1.679, p = 0.004, any; OR = 1.683, p = 0.005, endocrine). There was no statistically significant change in odds with hospital volume.
    Conclusions: Further investigation into the effect of single surgeon versus hospital volume on the risk of complications in pediatric thyroid cancer surgery is warranted.
    MeSH term(s) Humans ; Child ; Adolescent ; Thyroidectomy/adverse effects ; Thyroidectomy/methods ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Postoperative Complications/surgery ; Thyroid Neoplasms/surgery ; Hospitals ; Surgeons ; Retrospective Studies
    Language English
    Publishing date 2023-04-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82063-5
    ISSN 1096-9098 ; 0022-4790
    ISSN (online) 1096-9098
    ISSN 0022-4790
    DOI 10.1002/jso.27264
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Rural Otolaryngology Care Disparities: A Scoping Review.

    Urban, Matthew J / Shimomura, Aoi / Shah, Swapnil / Losenegger, Tasher / Westrick, Jennifer / Jagasia, Ashok A

    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

    2022  Volume 166, Issue 6, Page(s) 1219–1227

    Abstract: Objective: To broadly synthesize the literature regarding rural health disparities in otolaryngology, categorize findings, and identify research gaps to stimulate future work.: Study design: Scoping review.: Data sources: A comprehensive ... ...

    Abstract Objective: To broadly synthesize the literature regarding rural health disparities in otolaryngology, categorize findings, and identify research gaps to stimulate future work.
    Study design: Scoping review.
    Data sources: A comprehensive literature search was performed in the following databases: PubMed/MEDLINE, Scopus, Cochrane Central Register of Controlled Trials, Google Scholar, and CINAHL.
    Review methods: The methods were developed in concordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews checklist. Peer-reviewed, English-language, US-based studies examining a rural disparity in otolaryngology-related disease incidence, prevalence, diagnosis, treatment, or outcome were included. Descriptive studies, commentaries, reviews, and letters to the editor were excluded. Studies published prior to 1980 were excluded.
    Results: The literature search resulted in 1536 unique abstracts and yielded 79 studies that met final criteria for inclusion. Seventy-five percent were published after 2010. The distribution of literature was as follows: otology (34.2%), head and neck cancer (20.3%), endocrine surgery (13.9%), rhinology and allergy (8.9%), trauma (5.1%), laryngology (3.8%), other pediatrics (2.5%), and adult sleep (1.3%). Studies on otolaryngology health care systems also accounted for 10.1%. The most common topics studied were practice patterns (41%) and epidemiology (27%), while the Southeast (47%) was the most common US region represented, and database study (42%) was the most common study design.
    Conclusion: Overall, there was low-quality evidence with large gaps in the literature in all subspecialties, most notably facial plastic surgery, laryngology, adult sleep, and pediatrics. Importantly, there were few studies on intervention and zero studies on resident exposure to rural populations, which will be critical to making rural otolaryngology care more equitable in the future.
    MeSH term(s) Child ; Delivery of Health Care ; Humans ; Otolaryngology ; Peer Review ; Research Design ; Rural Population
    Language English
    Publishing date 2022-01-11
    Publishing country England
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 392085-9
    ISSN 1097-6817 ; 0161-6439 ; 0194-5998
    ISSN (online) 1097-6817
    ISSN 0161-6439 ; 0194-5998
    DOI 10.1177/01945998211068822
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Expert Opinion by Clinicians on the Use of Insulin Therapy in People with Hepatic Impairment.

    Chawla, Purvi / Shunmugavelu, Minakshisundaram / Jaggi, Shalini / Asirvatham, Arthur J / Basu, Debasis / Shah, Tejas / Farishta, Faraz / Das, Ashok Kumar

    The Journal of the Association of Physicians of India

    2023  Volume 71, Issue 2, Page(s) 11–12

    Abstract: People with type 2 diabetes mellitus (T2DM) have a higher risk of developing chronic liver disease (CLD) and its complications. T2DM, obesity, and insulin resistance are all strongly associated with nonalcoholic fatty liver disease (NAFLD). Conversely, ... ...

    Abstract People with type 2 diabetes mellitus (T2DM) have a higher risk of developing chronic liver disease (CLD) and its complications. T2DM, obesity, and insulin resistance are all strongly associated with nonalcoholic fatty liver disease (NAFLD). Conversely, people suffering from cirrhosis have reduced glucose tolerance in approximately 60% of cases, diabetes in 20% of cases, and insulin-mediated glucose clearance is lowered by 50% as compared with those who do not have cirrhosis. An exploratory review was conducted using existing published evidence from clinical studies on dosing and titrations of individual insulin formulations in people with CLD to optimize insulin dosage titration for minimizing hypoglycemia risk.pThis article discusses current hyperglycemia treatment techniques for patients with CLD as well as the consensus recommendations on insulin use in special populations with T2DM and hepatic impairment. Based on available evidence and expert diabetologists' recommendations, careful insulin dose titration, customized glycemic targets, and frequent glucose screening are recommended for optimal glycemic management without hypoglycemia in CLD. Long-acting insulin should be avoided or used when short-acting insulin fails to provide adequate glycemic control with raised fasting blood sugar levels. While the patient's glucose profile is being evaluated, the prandial insulin dose can be lowered by 25% initially. The dose can be titrated based on the patient's postprandial glycemic expression and whether their food intake meets the Child-Pugh scores A and B categories. Titrating premixed insulins is difficult for patients in class C since their appetite and overall health are constantly compromised and in flux.
    MeSH term(s) Humans ; Blood Glucose/metabolism ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/drug therapy ; Glucose ; Hypoglycemia/chemically induced ; Hypoglycemic Agents ; Insulin/therapeutic use ; Insulins/therapeutic use ; Liver Diseases
    Chemical Substances Blood Glucose ; Glucose (IY9XDZ35W2) ; Hypoglycemic Agents ; Insulin ; Insulins
    Language English
    Publishing date 2023-06-24
    Publishing country India
    Document type Journal Article
    ZDB-ID 800766-4
    ISSN 0004-5772
    ISSN 0004-5772
    DOI 10.5005/japi-11001-0171
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  7. Article ; Online: Is Multifocality a Predictor of Poor Outcome in Childhood and Adolescent Papillary Thyroid Carcinoma?

    Scholfield, Daniel W / Lopez, Joseph / Eagan, Alana / Antal, Zoltan / Tuttle, R Michael / Ghossein, Ronald / LaQuaglia, Michael / Shaha, Ashok R / Shah, Jatin P / Wong, Richard J / Patel, Snehal G / Ganly, Ian

    The Journal of clinical endocrinology and metabolism

    2023  Volume 108, Issue 12, Page(s) 3135–3144

    Abstract: Context: Total thyroidectomy in pediatric papillary thyroid carcinoma (PTC) is recommended in national guidelines because of the high incidence of multifocal disease (MFD).: Objective: To determine the incidence of MFD in childhood and adolescent vs ... ...

    Abstract Context: Total thyroidectomy in pediatric papillary thyroid carcinoma (PTC) is recommended in national guidelines because of the high incidence of multifocal disease (MFD).
    Objective: To determine the incidence of MFD in childhood and adolescent vs adult PTC and whether MFD is a predictor for poorer outcomes in childhood and adolescent PTC.
    Methods: We conducted an institutional review board-approved review of patients with PTC undergoing surgery (1986-2021) at Memorial Sloan Kettering Cancer Center. Clinical and pathological characteristics in patients with unifocal disease (UFD) and MFD were compared using Pearson's χ2 test. Survival outcomes were analyzed using the Kaplan-Meier method and log-rank test. Multivariate analysis assessed the impact of MFD on outcome.
    Results: MFD was less common in childhood and adolescent patients with PTC (45%; 127/283) than in adults (54%; 3023/5564; P = .002). Childhood and adolescent patients with UFD and MFD had similar tumor stage and PTC subtype at presentation, with no significant difference in histopathologic features. Median follow-up was 68 months. There was no significant difference in 5-year recurrence-free probability and overall survival was 100% in both groups. There was no significant difference in 5-year contralateral lobe PTC-free probability between patients with UFD and MFD treated with lobectomy. Multivariate analysis showed MFD was not a predictor for recurrence.
    Conclusion: MFD was less common in childhood and adolescent patients with PTC than adults and was not a predictor of poor outcome on multivariate analysis, with excellent long-term outcomes in all patients with PTC. MFD does not appear to warrant completion thyroidectomy in childhood and adolescent patients selected for lobectomy.
    MeSH term(s) Adult ; Humans ; Adolescent ; Child ; Thyroid Cancer, Papillary/pathology ; Thyroid Neoplasms/pathology ; Retrospective Studies ; Risk Factors ; Neoplasm Recurrence, Local/pathology ; Thyroidectomy/methods
    Language English
    Publishing date 2023-06-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3029-6
    ISSN 1945-7197 ; 0021-972X
    ISSN (online) 1945-7197
    ISSN 0021-972X
    DOI 10.1210/clinem/dgad369
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  8. Article ; Online: Complications of Thyroid Cancer Surgery in Pediatric Patients at a Tertiary Cancer Center.

    Scholfield, Daniel W / Lopez, Joseph / Badillo, Natalie Deana / Eagan, Alana / Levyn, Helena / LaQuaglia, Michael / Shaha, Ashok R / Shah, Jatin P / Wong, Richard J / Patel, Snehal G / Ganly, Ian

    Annals of surgical oncology

    2023  Volume 30, Issue 12, Page(s) 7781–7788

    Abstract: Background: The incidence of complications and risk factors for hypocalcemia after pediatric thyroid cancer surgery has not been clearly defined in the literature because most reports fail to distinguish between benign and malignant disease. The trend ... ...

    Abstract Background: The incidence of complications and risk factors for hypocalcemia after pediatric thyroid cancer surgery has not been clearly defined in the literature because most reports fail to distinguish between benign and malignant disease. The trend away from total thyroidectomy (TT) to thyroid lobectomy in low-risk disease means there is a need to clearly define the complication profile of malignant disease.
    Methods: After institutional review board (IRB) approval, a retrospective chart review was undertaken at Memorial Sloan Kettering Cancer Center for pediatric patients undergoing surgery for well-differentiated thyroid cancer from 1986 to 2021. Clinicopathologic characteristics and complications were evaluated. Multivariable analysis was performed to identify factors independently associated with postoperative hypocalcemia.
    Results: The study identified 307 pediatric patients with well-differentiated thyroid carcinoma (median follow-up period, 61 months). Of these patients, 69% underwent TT and 31% received a partial thyroidectomy. Among them, 40% had N0 disease, 28% had N1a disease, and 33% had N1b disease. Postoperatively, no patients experienced a neck hematoma, 1.6% had temporary unilateral vocal cord palsy (VCP), and 0.7% had permanent VCP due to recurrent laryngeal nerve (RLN) invasion. Temporary and permanent hypocalcemia occurred in respectively 32.6 % and 5.2 % of the patients. Multivariable analysis identified central neck dissection (CND) (odds ratio [OR] 3.30; p < 0.001) and N1 disease (OR 2.51; p = 0.036) as independent risk factors for temporary hypocalcemia and N stage (OR 3.64; p = 0.018) as a risk factor for permanent hypocalcemia.
    Conclusion: Pediatric thyroid cancer surgery results in low complication rates despite nodal metastases. Vocal cord paralysis is rare unless disease is found to be invading the RLN intraoperatively. Both N stage and CND are independent risk factors for hypocalcemia, helping to identify high-risk patients.
    MeSH term(s) Humans ; Child ; Retrospective Studies ; Hypocalcemia/etiology ; Postoperative Complications/epidemiology ; Thyroid Neoplasms/surgery ; Thyroid Neoplasms/pathology ; Neck Dissection/adverse effects ; Thyroidectomy/adverse effects ; Thyroidectomy/methods ; Adenocarcinoma/surgery ; Vocal Cord Paralysis/etiology
    Language English
    Publishing date 2023-08-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-023-14079-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Diffuse Sclerosing Papillary Thyroid Carcinoma: Clinicopathological Characteristics and Prognostic Implications Compared with Classic and Tall Cell Papillary Thyroid Cancer.

    Scholfield, Daniel W / Fitzgerald, Conall W / Alzumaili, Bayan / Eagan, Alana / Xu, Bin / Martinez, German / Tuttle, R Michael / Shaha, Ashok R / Shah, Jatin P / Wong, Richard J / Patel, Snehal G / Ghossein, Ronald A / Ganly, Ian

    Annals of surgical oncology

    2023  Volume 30, Issue 8, Page(s) 4761–4770

    Abstract: Background: The clinical behaviour and oncologic outcome of diffuse sclerosing papillary thyroid carcinoma (DS-PTC) is poorly understood. The objectives of this study were to compare the clinicopathological characteristics and oncological outcomes of DS- ...

    Abstract Background: The clinical behaviour and oncologic outcome of diffuse sclerosing papillary thyroid carcinoma (DS-PTC) is poorly understood. The objectives of this study were to compare the clinicopathological characteristics and oncological outcomes of DS-PTC to classic PTC (cPTC) and tall cell PTC (TC-PTC).
    Methods: After institutional review board approval, 86 DS-PTC, 2,080 cPTC, and 701 TC-PTC patients treated at MSKCC between 1986 and 2021 were identified. Clinicopathological characteristics were compared by using chi-square test. Kaplan-Meier and log rank were used to compare recurrence-free survival (RFS), disease-specific survival (DSS), and overall survival (OS). DS-PTC patients were propensity matched to cPTC and TC-PTC patients for further comparison.
    Results: DS-PTC patients were younger with more advanced disease than cPTC and TC-PTC (p < 0.05). Lymphovascular invasion (LVI), extranodal extension, and positive margins were more common in DS-PTC (p < 0.02). Propensity matching confirmed more aggressive histopathological features in DS-PTC. The median number of metastatic lymph nodes was significantly greater and DS-PTC metastases were RAI avid. DS-PTC 5-year RFS was 50.4% compared with 92.4% in cPTC and 88.4% in TC-PTC (p < 0.001). Multivariate analysis confirmed DS-PTC as an independent prognostic factor of recurrence. Ten-year DSS for DS-PTC was 100% compared with 97.1% in cPTC and 91.1% in TC-PTC. Differentiated high-grade, thyroid carcinoma DS had more advanced T-stage and worse 5-year RFS than DS-PTC.
    Conclusions: DS-PTC presents with more advanced clinicopathological features than cPTC and TC-PTC. Large-volume nodal metastases and LVI are characteristic features. Almost half of patients develop recurrence despite aggressive initial management. Despite this, with successful salvage surgery DSS is excellent.
    MeSH term(s) Humans ; Thyroid Cancer, Papillary/surgery ; Prognosis ; Carcinoma, Papillary/pathology ; Neoplasm Recurrence, Local/surgery ; Neoplasm Recurrence, Local/pathology ; Thyroid Neoplasms/pathology ; Retrospective Studies
    Language English
    Publishing date 2023-05-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-023-13589-y
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  10. Article ; Online: Changes in Primary Care Quality Associated With Implementation of the Veterans Health Administration Preventive Health Inventory.

    Wheat, Chelle L / Gunnink, Eric J / Rojas, Jorge / Shah, Ami / Nelson, Karin M / Wong, Edwin S / Gray, Kristen E / Stockdale, Susan E / Rosland, Ann-Marie / Chang, Evelyn T / Reddy, Ashok

    JAMA network open

    2023  Volume 6, Issue 4, Page(s) e238525

    Abstract: Importance: The COVID-19 pandemic caused significant disruptions in primary care delivery. The Veterans Health Administration (VHA) launched the Preventive Health Inventory (PHI) program-a multicomponent care management intervention, including a ... ...

    Abstract Importance: The COVID-19 pandemic caused significant disruptions in primary care delivery. The Veterans Health Administration (VHA) launched the Preventive Health Inventory (PHI) program-a multicomponent care management intervention, including a clinical dashboard and templated electronic health record note-to support primary care in delivering chronic disease care and preventive care that had been delayed by the pandemic.
    Objectives: To describe patient, clinician, and clinic correlates of PHI use in primary care clinics and to examine associations between PHI adoption and clinical quality measures.
    Design, setting, and participants: This quality improvement study used VHA administrative data from February 1, 2021, through February 28, 2022, from a national cohort of 216 VHA primary care clinics that have implemented the PHI. Participants comprised 829 527 veterans enrolled in primary care in clinics with the highest and lowest decile of PHI use as of February 2021.
    Exposure: Templated electronic health record note documenting use of the PHI.
    Main outcomes and measures: Diabetes and blood pressure clinical quality measures were the primary outcomes. Interrupted time series models were applied to estimate changes in diabetes and hypertension quality measures associated with PHI implementation. Low vs high PHI use was stratified at the facility level to measure whether systematic differences in uptake were associated with quality.
    Results: A total of 216 primary clinics caring for 829 527 unique veterans (mean [SD] age, 64.1 [16.9] years; 755 158 of 829 527 [91%] were men) formed the study cohort. Use of the PHI varied considerably across clinics. The clinics in the highest decile of PHI use completed a mean (SD) of 32 997.4 (14 019.3) notes in the electronic health record per 100 000 veterans compared with 56.5 (35.3) notes per 100 000 veterans at the clinics in the lowest decile of use (P < .001). Compared with the clinics with the lowest use of the PHI, clinics with the highest use had a larger mean (SD) clinic size (12 072 [7895] patients vs 5713 [5825] patients; P < .001), were more likely to be urban (91% vs 57%; P < .001), and served more non-Hispanic Black veterans (16% vs 5%; P < .001) and Hispanic veterans (14% vs 4%; P < .001). Staffing did not differ meaningfully between high- and low-use clinics (mean [SD] ratio of full-time equivalent staff to clinician, 3.4 [1.2] vs 3.4 [0.8], respectively; P < .001). After PHI implementation, compared with the clinics with the lowest use, those with the highest use had fewer veterans with a hemoglobin A1c greater than 9% or missing (mean [SD], 6577 [3216] per 100 000 veterans at low-use clinics; 9928 [4236] per 100 000 veterans at high-use clinics), more veterans with an annual hemoglobin A1c measurement (mean [SD], 13 181 [5625] per 100 000 veterans at high-use clinics; 8307 [3539] per 100 000 veterans at low-use clinics), and more veterans with adequate blood pressure control (mean [SD], 20 582 [12 201] per 100 000 veterans at high-use clinics; 12 276 [6850] per 100 000 veterans at low-use clinics).
    Conclusions and relevance: This quality improvement study of the implementation of the VHA PHI suggests that higher use of a multicomponent care management intervention was associated with improved quality-of-care metrics. The study also found significant variation in PHI uptake, with higher uptake associated with clinics with more racial and ethnic diversity and larger, urban clinic sites.
    MeSH term(s) Male ; Humans ; Middle Aged ; Female ; Glycated Hemoglobin ; Pandemics ; Veterans Health ; COVID-19/epidemiology ; COVID-19/prevention & control ; Quality of Health Care ; Diabetes Mellitus/epidemiology ; Diabetes Mellitus/therapy
    Chemical Substances Glycated Hemoglobin
    Language English
    Publishing date 2023-04-03
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2023.8525
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