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  1. Article ; Online: Reflexsynkope – oder mehr? : Iktale Asystolie!

    Etgen, Thorleif / Neuberger, Hans-Ruprecht

    Innere Medizin (Heidelberg, Germany)

    2022  Volume 63, Issue 10, Page(s) 1085–1091

    Abstract: A 59-year-old male patient was admitted for possible reflex syncope following loss of consciousness during urination. During the visit, a malaise with unconsciousness occurred. Holter ECG at that time showed increasing sinus bradycardia with transition ... ...

    Title translation Reflex syncope-or more? : Ictal asystole!
    Abstract A 59-year-old male patient was admitted for possible reflex syncope following loss of consciousness during urination. During the visit, a malaise with unconsciousness occurred. Holter ECG at that time showed increasing sinus bradycardia with transition to a junctional escape rhythm (30/min); in addition, there were several sinus pauses > 2.0 s (the longest almost 10 s). This malaise occurred again during routine EEG, when a focal epileptic seizure on the right fronto-temporal with sinus bradycardia after 15 s was documented. Thus, the diagnosis of ictal asystole was made, anticonvulsant therapy was started, and a cardiac pacemaker was implanted.
    MeSH term(s) Anticonvulsants/therapeutic use ; Arrhythmias, Cardiac/drug therapy ; Bradycardia/complications ; Electrocardiography ; Electroencephalography ; Heart Arrest/diagnosis ; Humans ; Male ; Middle Aged ; Reflex ; Seizures/complications ; Sick Sinus Syndrome/drug therapy ; Syncope, Vasovagal/diagnosis
    Chemical Substances Anticonvulsants
    Language German
    Publishing date 2022-07-07
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ISSN 2731-7099
    ISSN (online) 2731-7099
    DOI 10.1007/s00108-022-01374-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Performance of an implantable cardioverter-defibrillator lead family.

    Klampfleitner, Stefanie / Mundel, Markus / Schinke, Karin / Neuberger, Hans-Ruprecht

    Journal of cardiovascular electrophysiology

    2023  Volume 34, Issue 3, Page(s) 700–709

    Abstract: Background: Lead failure is the major limitation in implantable cardioverter-defibrillator (ICD) therapy. Long-term follow-up data for Biotronik Linox ICD leads are limited. Therefore, we analyzed the performance of all these leads implanted at our ... ...

    Abstract Background: Lead failure is the major limitation in implantable cardioverter-defibrillator (ICD) therapy. Long-term follow-up data for Biotronik Linox ICD leads are limited. Therefore, we analyzed the performance of all these leads implanted at our institution.
    Materials and methods: All Linox and Linox Smart ICD leads implanted between 2006 and 2015 were identified. Lead failure was defined as electrical dysfunction (oversensing, abnormal impedance, exit block). Lead survival was described, according to Kaplan-Meier. Associations between lead failure and specific variables were examined. p < .05 was considered significant.
    Results: We included 417 ICD leads. The median follow-up time for Linox (n = 205) was 81 months and for Linox Smart (n = 212) 75 months. During that follow-up time, 30 Linox (14.6%) and 16 Linox Smart leads (7.6%) showed a malfunction. The 5-year lead survival probability was 97.4% for Linox and 95.2% for Linox Smart (log-rank test, p = .19). The 6- and 8-year lead survival probability for Linox was 93.6% and 84.6%, and for Linox Smart 93% and 91.9%. The only factor significantly associated with lead failure was younger patient age at implantation (hazard ratio/year: 0.97, 95% CI: 0.94-0.99, p = .002).
    Conclusion: This relatively large study with a long follow-up period highlights a relevant failure rate of Biotronik Linox leads. The performance of Linox versus Linox Smart ICD leads was comparable. Although we show an acceptable 5-year lead survival probability, we observed a marked drop after just 1 more year of follow-up. In an era of improving heart failure survival probability, a prolonged follow-up of ICD leads is increasingly clinically relevant.
    MeSH term(s) Humans ; Defibrillators, Implantable ; Proportional Hazards Models ; Electric Impedance
    Language English
    Publishing date 2023-01-22
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1025989-2
    ISSN 1540-8167 ; 1045-3873
    ISSN (online) 1540-8167
    ISSN 1045-3873
    DOI 10.1111/jce.15804
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2863: Show issues Location:
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  3. Book ; Thesis: Charakterisierung der Kollagen bindenden Domäne des Yersinia-Adhäsins Yad-A

    Neuberger, Hans-Ruprecht

    1995  

    Author's details vorgelegt von Hans-Ruprecht Neuberger
    Language German
    Size 73 S. : graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Würzburg, Univ., Diss., 1996
    HBZ-ID HT007321499
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    96 D 3119 order for loan Magazin

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  4. Article ; Online: Does renal denervation target the substrate or the trigger for ventricular arrhythmias?

    Linz, Dominik / Neuberger, Hans-Ruprecht

    Journal of cardiovascular electrophysiology

    2013  Volume 24, Issue 12, Page(s) E20

    MeSH term(s) Catheter Ablation ; Humans ; Kidney/innervation ; Male ; Myocardial Infarction/therapy ; Percutaneous Coronary Intervention ; Sympathectomy/methods ; Tachycardia, Ventricular/surgery ; Thrombectomy ; Ventricular Fibrillation/surgery
    Language English
    Publishing date 2013-12
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 1025989-2
    ISSN 1540-8167 ; 1045-3873
    ISSN (online) 1540-8167
    ISSN 1045-3873
    DOI 10.1111/jce.12284
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  5. Article ; Online: Chronic kidney disease and atrial fibrillation.

    Linz, Dominik / Neuberger, Hans-Ruprecht

    Heart rhythm

    2012  Volume 9, Issue 12, Page(s) 2032–2033

    MeSH term(s) Animals ; Atrial Fibrillation/etiology ; Blood Pressure ; Male ; Oxidative Stress/physiology ; Renal Insufficiency, Chronic/complications
    Language English
    Publishing date 2012-12
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2012.08.024
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  6. Article ; Online: Obstructive sleep apnea: the suffocated atrium?

    Linz, Dominik / Neuberger, Hans-Ruprecht

    Heart rhythm

    2012  Volume 9, Issue 3, Page(s) 328–329

    MeSH term(s) Atrial Fibrillation ; Female ; Heart Atria/physiopathology ; Humans ; Hypoxia ; Male ; Sinoatrial Node/physiopathology ; Sleep Apnea, Obstructive
    Language English
    Publishing date 2012-03
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2011.10.031
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  7. Article ; Online: Treatment of obstructive sleep apnoea improves metabolic conditions and prevents initiation of antiarrhythmic therapy in a patient with atrial fibrillation.

    Linz, Dominik / Ukena, Christian / Neuberger, Hans-Ruprecht

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

    2014  Volume 16, Issue 2, Page(s) 245

    MeSH term(s) Anti-Arrhythmia Agents/therapeutic use ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/physiopathology ; Atrial Fibrillation/prevention & control ; Atrial Premature Complexes/diagnosis ; Atrial Premature Complexes/physiopathology ; Atrial Premature Complexes/prevention & control ; Continuous Positive Airway Pressure ; Electrocardiography, Ambulatory ; Humans ; Male ; Metabolic Syndrome/diagnosis ; Metabolic Syndrome/physiopathology ; Metabolic Syndrome/therapy ; Middle Aged ; Predictive Value of Tests ; Recurrence ; Risk Factors ; Severity of Illness Index ; Sleep Apnea, Obstructive/diagnosis ; Sleep Apnea, Obstructive/physiopathology ; Sleep Apnea, Obstructive/therapy ; Time Factors ; Treatment Outcome
    Chemical Substances Anti-Arrhythmia Agents
    Language English
    Publishing date 2014-02
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1449879-0
    ISSN 1532-2092 ; 1099-5129
    ISSN (online) 1532-2092
    ISSN 1099-5129
    DOI 10.1093/europace/eut233
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    Zs.A 5434: Show issues Location:
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  8. Article: Komplikation der Hypertonie : Vorhofflimmern.

    Ukena, Christian / Neuberger, Hans-Ruprecht / Böhm, Michael

    MMW Fortschritte der Medizin

    2011  Volume 153, Issue 41, Page(s) 47–49

    Language German
    Publishing date 2011-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1478211-x
    ISSN 1438-3276
    ISSN 1438-3276
    DOI 10.1007/BF03368900
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  9. Book ; Online ; Thesis: Atriale Elektrophysiologie und Serummarker des Kollagenstoffwechsels bei Patienten mit paroxsysmalem Vorhofflimmern

    Azone, Ines Babette [Verfasser] / Neuberger, Hans-Ruprecht [Akademischer Betreuer]

    2015  

    Author's details Ines Babette Azone. Betreuer: Hans-Ruprecht Neuberger
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Saarländische Universitäts- und Landesbibliothek
    Publishing place Saarbrücken
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  10. Article ; Online: Bidirectional ventricular tachycardia in a patient with exacerbation of chronic obstructive pulmonary disease.

    Adam, Oliver / Ukena, Christian / Böhm, Michael / Neuberger, Hans-Ruprecht

    Clinical research in cardiology : official journal of the German Cardiac Society

    2012  Volume 101, Issue 10, Page(s) 851–852

    MeSH term(s) Aged ; Echocardiography ; Electrocardiography ; Humans ; Male ; Pulmonary Disease, Chronic Obstructive/complications ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Tachycardia, Ventricular/diagnosis ; Tachycardia, Ventricular/etiology ; Tachycardia, Ventricular/physiopathology ; Ventricular Function, Left
    Language English
    Publishing date 2012-05-03
    Publishing country Germany
    Document type Case Reports ; Letter
    ZDB-ID 2213295-8
    ISSN 1861-0692 ; 1861-0684
    ISSN (online) 1861-0692
    ISSN 1861-0684
    DOI 10.1007/s00392-012-0462-0
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