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  1. Article ; Online: Evaluation of Health-Habits with the S.M.A.R.T. Questionnaire

    Francesco Vincenzo Ferraro / Ferdinando Ivano Ambra / Maria Luisa Iavarone

    Education Sciences, Vol 10, Iss 285, p

    An Observational Study

    2020  Volume 285

    Abstract: ... S.M.A.R.T.) questionnaire to identify the youths that present a higher risk of delinquency ... The following research aims to explore preliminary data from 501 adolescents completing the S.M.A.R.T ... Our results produce the first data set on a cohort of young adolescents in Italy using the S.M.A.R.T ...

    Abstract The civil education approach uses sports practise as a preventive intervention to increase self-awareness and to help modulate emotion in adolescents. Indeed, sports participation results in a better quality of life, more favourable cardio-metabolic and sleeping profiles and a healthier body composition. Adolescents involved in sport activities also report a higher level of social and emotional skills, and reduced mental health distress. However, the Italian school’s program provides only two hours weekly of physical education, with lack of options and participation. In alignment with the civil educational approach, the research team aims to develop a predictive sport, movement, eating habits, relationships and technologies (S.M.A.R.T.) questionnaire to identify the youths that present a higher risk of delinquency. The following research aims to explore preliminary data from 501 adolescents completing the S.M.A.R.T. The results show that the female group (n = 260) was healthier than the male group (n = 241); particularly, the female group demonstrated a higher level of self-awareness in the use of technologies ( p < 0.05). Our results produce the first data set on a cohort of young adolescents in Italy using the S.M.A.R.T. questionnaire. The questionnaire possesses a high response rate and should now be implemented towards validation.
    Keywords pedagogy ; sport science ; transdisciplinary ; childhood learning ; technologies ; relationship ; Education ; L
    Subject code 796
    Language English
    Publishing date 2020-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Air entrapment as a cause of S-ICD inappropriate shocks.

    Iavarone, Michele / Russo, Vincenzo

    Heart rhythm

    2022  Volume 19, Issue 10, Page(s) 1751–1752

    MeSH term(s) Defibrillators, Implantable/adverse effects ; Electric Countershock ; Equipment Failure
    Language English
    Publishing date 2022-05-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2022.05.012
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  3. Article ; Online: Evaluating the risk-benefit ratio of immunotherapy according to liver-functional reserve in advanced HCC: the dark side of the moon.

    Cabibbo, Giuseppe / Celsa, Ciro / Alimenti, Eleonora / Iavarone, Massimo

    Hepatology (Baltimore, Md.)

    2023  Volume 77, Issue 4, Page(s) 1074–1077

    MeSH term(s) Humans ; Carcinoma, Hepatocellular/therapy ; Liver Neoplasms/therapy ; Moon ; Immunotherapy/adverse effects
    Language English
    Publishing date 2023-01-03
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 604603-4
    ISSN 1527-3350 ; 0270-9139
    ISSN (online) 1527-3350
    ISSN 0270-9139
    DOI 10.1097/HEP.0000000000000205
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  4. Article: Air entrapment as a cause of early inappropriate shocks after subcutaneous defibrillator implant: A case series.

    Iavarone, Michele / Ammendola, Ernesto / Rago, Anna / Russo, Vincenzo

    Indian pacing and electrophysiology journal

    2023  Volume 23, Issue 3, Page(s) 84–87

    Abstract: Inappropriate shock (IAS) is the most frequent device-related complication among patients with subcutaneous implantable cardioverter-defibrillator (S-ICD). Air entrapment (AE) has been described as an underdiagnosed cause of early postimplant IAS. We ... ...

    Abstract Inappropriate shock (IAS) is the most frequent device-related complication among patients with subcutaneous implantable cardioverter-defibrillator (S-ICD). Air entrapment (AE) has been described as an underdiagnosed cause of early postimplant IAS. We report 6 consecutive cases of early IAS after S-ICD implant, in whom the electrogram analysis (EGM) and/or chest radiography (CXR) were consistent with AE.
    Language English
    Publishing date 2023-02-04
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2123606-9
    ISSN 0972-6292
    ISSN 0972-6292
    DOI 10.1016/j.ipej.2023.02.001
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  5. Article ; Online: Interatrial block as a first clinical presentation of atrial cardiomyopathy related to a novel LMNA variant: a case report.

    Iavarone, Michele / Covino, Simona / Petillo, Roberta / Russo, Vincenzo

    European heart journal. Case reports

    2023  Volume 7, Issue 12, Page(s) ytad532

    Abstract: Background: Interatrial block (IAB) is a conduction delay in Bachmann's bundle with a well-described association with structural heart disease, supraventricular arrhythmias, and cardiovascular events.: Case summary: We report the case of an ... ...

    Abstract Background: Interatrial block (IAB) is a conduction delay in Bachmann's bundle with a well-described association with structural heart disease, supraventricular arrhythmias, and cardiovascular events.
    Case summary: We report the case of an asymptomatic 35-year-old man in whom the presence of IAB at electrocardiogram led to a comprehensive evaluation including speckle-tracking echocardiography, 24 h Holter monitoring, and genetic testing. Speckle-tracking echocardiography demonstrated a decrease in the longitudinal strain of interventricular septum, a typical feature of LMNA-related cardiomyopathy, and decreased indices of left atrial deformation. A diagnosis of cardiac laminopathy related to the frame shift variant c.1367 (p.Asn456Thrfs*24) of the LMNA gene was made. A dual-chamber implantable cardioverter defibrillator implantation was performed for the high risk of life-threatening ventricular tachyarrhythmias.
    Discussion: This case demonstrates that IAB could be a rare presentation of a life-threatening laminopathy. Strain echocardiography is an essential tool to evaluate the deposition of fibrosis tissue in subclinical cardiomyopathies. Our report describes a novel variant of LMNA gene associated with a high risk of sudden cardiac death.
    Language English
    Publishing date 2023-10-27
    Publishing country England
    Document type Case Reports
    ISSN 2514-2119
    ISSN (online) 2514-2119
    DOI 10.1093/ehjcr/ytad532
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  6. Article: Influence of hand starting position on radial line bisection.

    Ricci, Mariateresa / Iavarone, Alessandro / Ilardi, Ciro Rosario / Chieffi, Sergio

    Frontiers in psychology

    2023  Volume 14, Page(s) 1293624

    Abstract: When normal individuals are asked to localize and mark the midpoint of a radial line, they tend to bisect it farther than the true center. It has been suggested that radial misbisection depends on the presence of a visual attentional bias directed toward ...

    Abstract When normal individuals are asked to localize and mark the midpoint of a radial line, they tend to bisect it farther than the true center. It has been suggested that radial misbisection depends on the presence of a visual attentional bias directed toward the far space. The aim of the present study was to investigate whether the localization of the center of radial lines was affected by the starting position of the hand. There were two starting positions: one between the body and the radial line ("near"), the other beyond the radial line ("far"). Thirty-four subjects participated in the experiment. The results showed that (i) participants bisected radial lines farther than the true center, measured with reference to their body, in both near and far condition, and (ii) bisection errors in the near condition were greater than those in the far condition. We suggest that hand starting position and direction of ongoing movement influenced radial line misbisection by modulating visual attentional bias directed to far space.
    Language English
    Publishing date 2023-12-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2023.1293624
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  7. Article ; Online: The Authors' Reply.

    Invernizzi, Federica / Iavarone, Massimo

    Transplantation

    2020  Volume 104, Issue 8, Page(s) e244

    MeSH term(s) Carcinoma, Hepatocellular ; Humans ; Liver Neoplasms ; Liver Transplantation ; Neoplasm Recurrence, Local ; Sorafenib ; TOR Serine-Threonine Kinases
    Chemical Substances Sorafenib (9ZOQ3TZI87) ; TOR Serine-Threonine Kinases (EC 2.7.1.1)
    Language English
    Publishing date 2020-07-23
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000003229
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  8. Article ; Online: Stimulation of the catalytic activity of the tyrosine kinase Btk by the adaptor protein Grb2.

    Nocka, Laura M / Eisen, Timothy J / Iavarone, Anthony T / Groves, Jay T / Kuriyan, John

    eLife

    2023  Volume 12

    Abstract: The Tec-family kinase Btk contains a lipid-binding Pleckstrin homology and Tec homology (PH-TH) module connected by a proline-rich linker to a 'Src module', an SH3-SH2-kinase unit also found in Src-family kinases and Abl. We showed previously that Btk is ...

    Abstract The Tec-family kinase Btk contains a lipid-binding Pleckstrin homology and Tec homology (PH-TH) module connected by a proline-rich linker to a 'Src module', an SH3-SH2-kinase unit also found in Src-family kinases and Abl. We showed previously that Btk is activated by PH-TH dimerization, which is triggered on membranes by the phosphatidyl inositol phosphate PIP
    MeSH term(s) Protein-Tyrosine Kinases ; src Homology Domains ; src-Family Kinases ; Signal Transduction ; Dimerization
    Chemical Substances Protein-Tyrosine Kinases (EC 2.7.10.1) ; src-Family Kinases (EC 2.7.10.2)
    Language English
    Publishing date 2023-04-26
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.82676
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  9. Article: Management of Neuromuscular Blocking Agents in Critically Ill Patients with Lung Diseases.

    Iavarone, Ida Giorgia / Al-Husinat, Lou'i / Vélez-Páez, Jorge Luis / Robba, Chiara / Silva, Pedro Leme / Rocco, Patricia R M / Battaglini, Denise

    Journal of clinical medicine

    2024  Volume 13, Issue 4

    Abstract: The use of neuromuscular blocking agents (NMBAs) is common in the intensive care unit (ICU). NMBAs have been used in critically ill patients with lung diseases to optimize mechanical ventilation, prevent spontaneous respiratory efforts, reduce the work ... ...

    Abstract The use of neuromuscular blocking agents (NMBAs) is common in the intensive care unit (ICU). NMBAs have been used in critically ill patients with lung diseases to optimize mechanical ventilation, prevent spontaneous respiratory efforts, reduce the work of breathing and oxygen consumption, and avoid patient-ventilator asynchrony. In patients with acute respiratory distress syndrome (ARDS), NMBAs reduce the risk of barotrauma and improve oxygenation. Nevertheless, current guidelines and evidence are contrasting regarding the routine use of NMBAs. In status asthmaticus and acute exacerbation of chronic obstructive pulmonary disease, NMBAs are used in specific conditions to ameliorate patient-ventilator synchronism and oxygenation, although their routine use is controversial. Indeed, the use of NMBAs has decreased over the last decade due to potential adverse effects, such as immobilization, venous thrombosis, patient awareness during paralysis, development of critical illness myopathy, autonomic interactions, ICU-acquired weakness, and residual paralysis after cessation of NMBAs use. The aim of this review is to highlight current knowledge and synthesize the evidence for the effects of NMBAs for critically ill patients with lung diseases, focusing on patient-ventilator asynchrony, ARDS, status asthmaticus, and chronic obstructive pulmonary disease.
    Language English
    Publishing date 2024-02-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13041182
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  10. Article ; Online: Mechanical ventilation in patients with acute respiratory distress syndrome: current status and future perspectives.

    Battaglini, Denise / Iavarone, Ida Giorgia / Robba, Chiara / Ball, Lorenzo / Silva, Pedro Leme / Rocco, Patricia R M

    Expert review of medical devices

    2023  Volume 20, Issue 11, Page(s) 905–917

    Abstract: Introduction: Although there has been extensive research on mechanical ventilation for acute respiratory distress syndrome (ARDS), treatment remains mainly supportive. Recent studies and new ventilatory modes have been proposed to manage patients with ... ...

    Abstract Introduction: Although there has been extensive research on mechanical ventilation for acute respiratory distress syndrome (ARDS), treatment remains mainly supportive. Recent studies and new ventilatory modes have been proposed to manage patients with ARDS; however, the clinical impact of these strategies remains uncertain and not clearly supported by guidelines. The aim of this narrative review is to provide an overview and update on ventilatory management for patients with ARDS.
    Areas covered: This article reviews the literature regarding mechanical ventilation in ARDS. A comprehensive overview of the principal settings for the ventilator parameters involved is provided as well as a report on the differences between controlled and assisted ventilation. Additionally, new modes of assisted ventilation are presented and discussed. The evidence concerning rescue strategies, including recruitment maneuvers and extracorporeal membrane oxygenation support, is analyzed. PubMed, EBSCO, and the Cochrane Library were searched up until June 2023, for relevant literature.
    Expert opinion: Available evidence for mechanical ventilation in cases of ARDS suggests the use of a personalized mechanical ventilation strategy. Although promising, new modes of assisted mechanical ventilation are still under investigation and guidelines do not recommend rescue strategies as the standard of care. Further research on this topic is required.
    MeSH term(s) Humans ; Respiration, Artificial ; Respiratory Distress Syndrome/therapy ; Ventilators, Mechanical ; Extracorporeal Membrane Oxygenation
    Language English
    Publishing date 2023-09-07
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2250857-0
    ISSN 1745-2422 ; 1743-4440
    ISSN (online) 1745-2422
    ISSN 1743-4440
    DOI 10.1080/17434440.2023.2255521
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