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  1. Article ; Online: Editorial Commentary.

    Scarpato, Kristen R / Miller, Nicole L

    Urology practice

    2024  Volume 11, Issue 3, Page(s) 596

    MeSH term(s) United States ; Fellowships and Scholarships ; Urology ; Editorial Policies ; Demography
    Language English
    Publishing date 2024-03-01
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2352-0787
    ISSN (online) 2352-0787
    DOI 10.1097/UPJ.0000000000000548
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  2. Article ; Online: EDITORIAL COMMENT.

    Miller, Nicole L

    Urology

    2021  Volume 151, Page(s) 52–53

    Language English
    Publishing date 2021-05-10
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 192062-5
    ISSN 1527-9995 ; 0090-4295
    ISSN (online) 1527-9995
    ISSN 0090-4295
    DOI 10.1016/j.urology.2020.06.099
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  3. Article ; Online: Biliary Ascites.

    Miller, Nicole L / Drapeau, Joezer / Abel, Erika S

    Journal of general internal medicine

    2023  Volume 38, Issue 5, Page(s) 1310

    Language English
    Publishing date 2023-02-10
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 639008-0
    ISSN 1525-1497 ; 0884-8734
    ISSN (online) 1525-1497
    ISSN 0884-8734
    DOI 10.1007/s11606-023-08074-x
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  4. Article ; Online: Creation and characterization of a recombinant mammalian orthoreovirus expressing σ1 fusion proteins encoding human epidermal growth factor receptor 2 peptides.

    Jandick, Nicole A / Miller, Cathy L

    Virology

    2023  Volume 587, Page(s) 109871

    Abstract: Mammalian orthoreovirus (MRV) is an oncolytic virus that has been tested in over 30 clinical trials. Increased clinical success has been achieved when MRV is used in combination with other onco-immunotherapies. This has led the field to explore the ... ...

    Abstract Mammalian orthoreovirus (MRV) is an oncolytic virus that has been tested in over 30 clinical trials. Increased clinical success has been achieved when MRV is used in combination with other onco-immunotherapies. This has led the field to explore the creation of recombinant MRVs which incorporate immunotherapeutic sequences into the virus genome. This work focuses on creation and characterization of a recombinant MRV, S1/HER2nhd, which encodes a truncated σ1 protein fused in frame with three human epidermal growth factor receptor 2 (HER2) peptides (E75, AE36, and GP2) known to induce HER2 specific CD8
    MeSH term(s) Animals ; Humans ; Orthoreovirus, Mammalian/genetics ; Recombinant Fusion Proteins/genetics ; Neoplasms ; Peptides ; Mammals
    Chemical Substances ERBB2 protein, human (EC 2.7.10.1) ; Recombinant Fusion Proteins ; Peptides
    Language English
    Publishing date 2023-08-19
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 200425-2
    ISSN 1096-0341 ; 0042-6822
    ISSN (online) 1096-0341
    ISSN 0042-6822
    DOI 10.1016/j.virol.2023.109871
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  5. Article ; Online: Nonopioid Pain Management Pathways for Stone Disease.

    Cabo, Jackson J S / Miller, Nicole L

    Journal of endourology

    2023  Volume 38, Issue 2, Page(s) 108–120

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Humans ; Analgesics, Opioid/adverse effects ; Anti-Inflammatory Agents, Non-Steroidal ; Kidney Calculi/drug therapy ; Pain Management ; Pain, Postoperative/drug therapy ; Practice Patterns, Physicians' ; Randomized Controlled Trials as Topic ; Renal Colic
    Chemical Substances Analgesics, Opioid ; Anti-Inflammatory Agents, Non-Steroidal
    Language English
    Publishing date 2023-12-22
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 356931-7
    ISSN 1557-900X ; 0892-7790
    ISSN (online) 1557-900X
    ISSN 0892-7790
    DOI 10.1089/end.2023.0266
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    Zs.MO 208: Show issues

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  6. Article ; Online: Editorial Comment.

    Miller, Nicole L

    The Journal of urology

    2018  Volume 199, Issue 6, Page(s) 1598

    MeSH term(s) Humans ; Laser Therapy ; Lasers, Solid-State ; Male ; Prostate ; Prostatectomy ; Volatilization
    Language English
    Publishing date 2018-03-07
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1016/j.juro.2018.01.086
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    Zs.MO 331: Show issues

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  7. Article: Mammalian orthoreovirus infection in human epidermal growth factor receptor 2 positive (HER2+) breast cancer cells.

    Jandick, Nicole A / Kirner, Nicolette / Miller, Cathy L

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Mammalian orthoreovirus (MRV) is a clinically benign oncolytic virus which has been investigated for use in multiple cancer types, including breast cancer (BC). In human clinical trials, MRV has been shown to be safe, and multiple BC patients have shown ... ...

    Abstract Mammalian orthoreovirus (MRV) is a clinically benign oncolytic virus which has been investigated for use in multiple cancer types, including breast cancer (BC). In human clinical trials, MRV has been shown to be safe, and multiple BC patients have shown partial responses to intratumoral and intravenous virus delivery. Combination therapies inclusive of MRV and current FDA approved BC chemotherapies are being investigated to target metastatic, early BC, and triple negative BC. Though MRV is being tested clinically, we still do not fully understand the highly variable patient responses to MRV therapy. One of the most aggressive BC subtypes is HER2+ BC, in which human epidermal growth factor receptor 2 (HER2) is dysregulated, resulting in increased growth, survival, and metastasis of cancer cells. FDA approved therapies, trastuzumab and pertuzumab, target HER2 to prevent signaling of the phosphoinositide 3-kinase (PI3K) pathway. However, recent findings show that accumulation of hypoxia inducible factor-1 alpha (HIF-1α) in HER2+ BC cells contributes to trastuzumab resistance. In this work, we provide evidence that MRV infects, replicates in, and kills HER2 overexpressing cells. MRV infection is also found to have variable effects on signaling pathways that activate or are activated by HER2 expression. Finally, we show that MRV reduces HIF-1α accumulation in all the cell lines tested, including a HER2+ BC cell line. These studies provide further evidence that MRV holds promise for use in conjunction with trastuzumab to treat HER2+ BC patients.
    Language English
    Publishing date 2023-05-10
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.05.10.540250
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  8. Article: Unmet Needs and Care Delivery Gaps Among Rural Cancer Survivors.

    Stout, Nicole L / Boatman, Dannell / Rice, Madeline / Branham, Emelia / Miller, Meadow / Salyer, Rachel

    Journal of patient experience

    2024  Volume 11, Page(s) 23743735241239865

    Abstract: Community-based healthcare delivery systems frequently lack cancer-specific survivorship support services. This leads to a burden of unmet needs that is magnified in rural areas. Using sequential mixed methods we assessed unmet needs among rural cancer ... ...

    Abstract Community-based healthcare delivery systems frequently lack cancer-specific survivorship support services. This leads to a burden of unmet needs that is magnified in rural areas. Using sequential mixed methods we assessed unmet needs among rural cancer survivors diagnosed between 2015 and 2021. The Supportive Care Needs Survey (SCNS) assessed 5 domains; Physical and Daily Living, Psychological, Support and Supportive Services, Sexual, and Health Information. Needs were analyzed across domains by cancer type. Survey respondents were recruited for qualitative interviews to identify care gaps. Three hundred and sixty two surveys were analyzed. Participants were 85% White (n = 349) 65% (n = 234) female and averaged 2.03 years beyond cancer diagnosis. Nearly half (49.5%) of respondents reported unmet needs, predominantly in physical, psychological, and health information domains. Needs differed by stage of disease. Eleven interviews identified care gap themes regarding; Finding Support and Supportive Services and Health Information regarding Care Delivery and Continuity of Care. Patients experience persistent unmet needs after a cancer diagnosis across multiple functional domains. Access to community-based support services and health information is lacking. Community based resources are needed to improve access to care for long-term cancer survivors.
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2857285-3
    ISSN 2374-3743 ; 2374-3735
    ISSN (online) 2374-3743
    ISSN 2374-3735
    DOI 10.1177/23743735241239865
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  9. Article ; Online: The role of fetal therapy in the management of mirror syndrome: a narrative review.

    Gavin, Nicole R / Forrest, Alexandra D / Rosner, Mara / Miller, Jena L / Baschat, Ahmet A

    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

    2024  Volume 37, Issue 1, Page(s) 2345307

    Abstract: Objectives: Mirror syndrome (MS) is a condition characterized by the presence of maternal, fetal, and placental edema and is reversible through delivery or pregnancy termination. As fetal hydrops itself may be amenable to treatment, we sought to ... ...

    Abstract Objectives: Mirror syndrome (MS) is a condition characterized by the presence of maternal, fetal, and placental edema and is reversible through delivery or pregnancy termination. As fetal hydrops itself may be amenable to treatment, we sought to determine outcomes for MS primarily managed by fetal therapy through a narrative review of the literature and cases managed at our fetal center.
    Study design: PubMed, Embase, Web of Science, Scopus, and Google Scholar databases were searched through January 2024 using key words: mirror syndrome, Ballantyne's syndrome, fetal hydrops, maternal hydrops, pseudotoxemia, triple edema, maternal recovery, fetal therapy, and resolution. Manuscripts describing primary management by fetal therapy that included maternal and fetal outcomes were identified. Clinical details of MS patients managed with fetal therapy at our center were also included for descriptive analysis.
    Results: 16 of 517 manuscripts (3.1%) described fetal therapy as the primary intended treatment in 17 patients. 3 patients managed at our center were included in the analysis. Among 20 patients undergoing primary fetal therapy for management of mirror syndrome, median gestational age of presentation was 24 weeks and 5 days gestation; predominant clinical findings were maternal edema (15/20), proteinuria (10/20), pulmonary edema (8/20), and hypertension (8/20); the primary laboratory abnormalities were anemia (8/20) and elevated creatinine or transaminases (5/20). Condition-specific fetal therapies led to resolution of hydrops in 17 (85%) cases and MS in 19 (95%) cases. The median time to hydrops resolution was 7.5 days and to resolution of mirror syndrome was 10 days. Fetal therapy prolonged pregnancy by a median of 10 weeks with a median gestational age of 35 weeks and 5 days at delivery. All women delivered for indications other than mirror syndrome and 19/20 fetuses survived.
    Conclusion: In appropriately selected cases, MS often resolves after fetal therapy of hydrops allowing for safe pregnancy prolongation with good maternal and infant outcomes.
    MeSH term(s) Humans ; Pregnancy ; Hydrops Fetalis/therapy ; Hydrops Fetalis/diagnosis ; Female ; Fetal Therapies/methods ; Edema/therapy ; Syndrome
    Language English
    Publishing date 2024-04-28
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2077261-0
    ISSN 1476-4954 ; 1057-0802 ; 1476-7058
    ISSN (online) 1476-4954
    ISSN 1057-0802 ; 1476-7058
    DOI 10.1080/14767058.2024.2345307
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    Zs.A 3510: Show issues Location:
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  10. Article ; Online: Editorial Comment on: Age, Body Mass Index, and Gender Predict 24-Hour Urine Parameters in Recurrent Idiopathic Calcium Oxalate Stone Formers by Otto et al. (From: Otto BJ, Bozorgmehri S, Kuo J, et al. J Endourol 2017;31:1335-1341).

    Miller, Nicole L

    Journal of endourology

    2017  Volume 32, Issue 1, Page(s) 76

    MeSH term(s) Body Mass Index ; Calcium Oxalate/urine ; Humans ; Kidney Calculi ; Urinary Calculi/urine
    Chemical Substances Calcium Oxalate (2612HC57YE)
    Language English
    Publishing date 2017-12-13
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 356931-7
    ISSN 1557-900X ; 0892-7790
    ISSN (online) 1557-900X
    ISSN 0892-7790
    DOI 10.1089/end.2017.0872
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