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  1. Article ; Online: 11th ENOR meeting: Oxysterols in human health and diseases.

    Poirot, Marc / Iuliano, Luigi / Griffiths, William J / Lizard, Gerard

    The Journal of steroid biochemistry and molecular biology

    2024  Volume 239, Page(s) 106495

    MeSH term(s) Humans ; Oxysterols
    Chemical Substances Oxysterols
    Language English
    Publishing date 2024-02-27
    Publishing country England
    Document type Editorial
    ZDB-ID 1049188-0
    ISSN 1879-1220 ; 0960-0760
    ISSN (online) 1879-1220
    ISSN 0960-0760
    DOI 10.1016/j.jsbmb.2024.106495
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    Zs.A 708: Show issues Location:
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  2. Article ; Online: European Network for oxysterol research (ENOR): 10th ENOR symposium - Web meeting.

    Lizard, Gérard / Poirot, Marc / Iuliano, Luigi

    Steroids

    2023  Volume 195, Page(s) 109242

    MeSH term(s) Oxysterols
    Chemical Substances Oxysterols
    Language English
    Publishing date 2023-04-22
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 80312-1
    ISSN 1878-5867 ; 0039-128X
    ISSN (online) 1878-5867
    ISSN 0039-128X
    DOI 10.1016/j.steroids.2023.109242
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  3. Article ; Online: Celebrating the 10th anniversary of the creation of the European Network for Oxysterol Research (ENOR).

    Lizard, Gérard / Poirot, Marc / Iuliano, Luigi

    The Journal of steroid biochemistry and molecular biology

    2022  Volume 221, Page(s) 106114

    MeSH term(s) Anniversaries and Special Events ; Oxysterols
    Chemical Substances Oxysterols
    Language English
    Publishing date 2022-04-12
    Publishing country England
    Document type Editorial
    ZDB-ID 1049188-0
    ISSN 1879-1220 ; 0960-0760
    ISSN (online) 1879-1220
    ISSN 0960-0760
    DOI 10.1016/j.jsbmb.2022.106114
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  4. Article ; Online: Management of Persistent Erectile Dysfunction after COVID-19 Infection

    Stefano Iuliano / Giuseppe Seminara / Maria Carmela Zagari / Luigi Di Luigi / Antonio Aversa

    Sexes, Vol 4, Iss 6, Pp 55-

    An 18-Month Follow-Up Case Report

    2023  Volume 64

    Abstract: The coronavirus disease 2019 (COVID-19) is an emerging pandemic caused by a novel coronavirus (SARS-CoV-2). Since December 2019 the new virus has spread all over the world and has become a major health problem also because of the public measures that ... ...

    Abstract The coronavirus disease 2019 (COVID-19) is an emerging pandemic caused by a novel coronavirus (SARS-CoV-2). Since December 2019 the new virus has spread all over the world and has become a major health problem also because of the public measures that could affect people’s sexual activity. We report a case of a 35-year-old married male admitted to the andrology outpatient clinic in July 2021 because of sudden onset erectile dysfunction (ED). The diagnostic workup showed no risk factor for ED, normal levels of testosterone, increased levels of endothelial dysfunction markers, such as CRP (C-Reactive Protein) and Endothelin-1, and reduced Vitamin D (VD) levels. Dynamic penile duplex ultrasound (D-PDU) revealed dysfunctional penile arterial flow. The five-item International Index of Erectile Function (IIEF-5) and the Short-Form Health Survey (SF-36) showed a reduction in all domain scores. The patient, initially unresponsive to the high dose oral phosphodiesterase 5 inhibitors (PDE-5is), was treated with vitamin-D and then submitted to LI-SWT (low intensity shockwave treatment), with a progressive clinical benefit at the 12-month follow-up. After 18 months, hormone levels persisted in normal ranges, with a consistent reduction in CRP and Endothelin-1. Additionally, IIEF-5, SF-36 and arterial flow significantly improved over the follow-up period. Thus far, the erectile function was restored and the patient is no more treated with PDE-5i.
    Keywords erectile dysfunction ; pandemic ; COVID-19 ; case report ; LI-SWT ; PDE-5i ; Psychology ; BF1-990 ; Special aspects of education ; LC8-6691 ; Medicine (General) ; R5-920
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: European network for oxysterol research (ENOR): 10 th anniversary.

    Lizard, Gérard / Poirot, Marc / Iuliano, Luigi

    The Journal of steroid biochemistry and molecular biology

    2021  Volume 214, Page(s) 105996

    MeSH term(s) Animals ; Bile Acids and Salts/chemistry ; Biomedical Research/trends ; Cholesterol/chemistry ; Congresses as Topic ; Europe ; Humans ; Oxysterols/chemistry ; Oxysterols/metabolism ; Physiology/methods ; Phytosterols/chemistry ; Societies, Medical
    Chemical Substances Bile Acids and Salts ; Oxysterols ; Phytosterols ; Cholesterol (97C5T2UQ7J)
    Language English
    Publishing date 2021-09-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 1049188-0
    ISSN 1879-1220 ; 0960-0760
    ISSN (online) 1879-1220
    ISSN 0960-0760
    DOI 10.1016/j.jsbmb.2021.105996
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  6. Article: Commentary: Case report: Mesothelioma and BAP1 tumor predisposition syndrome: implications for public health.

    Sassorossi, Carolina / Chiappetta, Marco / Congedo, Maria Teresa / Flamini, Sara / Campanella, Annalisa / Evangelista, Jessica / Iuliano, Rodolfo / Boccuto, Luigi / Lococo, Filippo

    Frontiers in oncology

    2023  Volume 13, Page(s) 1279786

    Language English
    Publishing date 2023-10-16
    Publishing country Switzerland
    Document type Journal Article ; Comment
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1279786
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  7. Article ; Online: Pathways of cholesterol oxidation via non-enzymatic mechanisms.

    Iuliano, Luigi

    Chemistry and physics of lipids

    2011  Volume 164, Issue 6, Page(s) 457–468

    Abstract: Cholesterol has many functions, including those that affect biophysical properties of membranes, and is a precursor to hormone synthesis. These actions are governed by enzymatic pathways that modify the sterol nucleus or the isooctyl tail. The addition ... ...

    Abstract Cholesterol has many functions, including those that affect biophysical properties of membranes, and is a precursor to hormone synthesis. These actions are governed by enzymatic pathways that modify the sterol nucleus or the isooctyl tail. The addition of oxygen to the cholesterol backbone produces its derivatives known as oxysterols. In addition to having an enzymatic origin, oxysterols can be formed in the absence of enzymatic catalysis in a pathway usually termed "autoxidation," which has been known for almost a century and observed under various experimental conditions. Autoxidation of cholesterol can occur through reactions initiated by free radical species, such as those arising from the superoxide/hydrogen peroxide/hydroxyl radical system and by non-radical highly reactive oxygen species such as singlet oxygen, HOCl, and ozone. The susceptibility of cholesterol to non-enzymatic oxidation has raised considerable interest in the function of oxysterols as biological effectors and potential biomarkers for the non-invasive study of oxidative stress in vivo.
    MeSH term(s) Animals ; Biomarkers/metabolism ; Cholesterol/metabolism ; Free Radicals/metabolism ; Humans ; Oxidation-Reduction ; Oxidative Stress
    Chemical Substances Biomarkers ; Free Radicals ; Cholesterol (97C5T2UQ7J)
    Language English
    Publishing date 2011-09
    Publishing country Ireland
    Document type Journal Article ; Review
    ZDB-ID 213869-4
    ISSN 1873-2941 ; 0009-3084
    ISSN (online) 1873-2941
    ISSN 0009-3084
    DOI 10.1016/j.chemphyslip.2011.06.006
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  8. Article ; Online: Cholesterol and related sterols autoxidation.

    Zerbinati, Chiara / Iuliano, Luigi

    Free radical biology & medicine

    2017  Volume 111, Page(s) 151–155

    Abstract: Cholesterol is a unique lipid molecule providing the building block for membranes, hormones, vitamin D and bile acid synthesis. Metabolism of cholesterol involves several enzymes acting on the sterol nucleus or the isooctyl tail. In the recent years, ... ...

    Abstract Cholesterol is a unique lipid molecule providing the building block for membranes, hormones, vitamin D and bile acid synthesis. Metabolism of cholesterol involves several enzymes acting on the sterol nucleus or the isooctyl tail. In the recent years, research interest has been focused on oxysterols, cholesterol derivatives generated by the addition of oxygen to the cholesterol backbone. Oxysterols can be produced enzymatically or by autoxidation. Autoxidation of cholesterol proceeds through type I or type II mechanisms. Type I autoxidation is initiated by free radical species, such as those arising from the superoxide/hydrogen peroxide/hydroxyl radical system. Type II autoxidation occurs stoichiometrically by non-radical highly reactive oxygen species such as singlet oxygen, HOCl, and ozone. The vulnerability of cholesterol towards high reactive species has raised considerable interest for mechanistic studies and for the potential biological activity of oxysterols, as well as for the use of oxysterols as biomarkers for the non-invasive study of oxidative stress in vivo.
    Language English
    Publishing date 2017-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 807032-5
    ISSN 1873-4596 ; 0891-5849
    ISSN (online) 1873-4596
    ISSN 0891-5849
    DOI 10.1016/j.freeradbiomed.2017.04.013
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  9. Article ; Online: Decline of immune humoral response after BNT162b2 vaccine.

    Ferri, Sonia / Polidoro, Alessandro / Ciacciarelli, Marco / Ceratti, Umberto / Congedo, Viviana / Mele, Maria / Coluzzi, Graziella / Spagnoli, Alessandra / Iuliano, Luigi

    The Journal of infection

    2022  Volume 84, Issue 4, Page(s) e34–e35

    MeSH term(s) Antibodies, Viral ; BNT162 Vaccine ; Humans ; Immunity, Humoral ; Vaccines
    Chemical Substances Antibodies, Viral ; Vaccines ; BNT162 Vaccine (N38TVC63NU)
    Language English
    Publishing date 2022-02-17
    Publishing country England
    Document type Letter
    ZDB-ID 424417-5
    ISSN 1532-2742 ; 0163-4453
    ISSN (online) 1532-2742
    ISSN 0163-4453
    DOI 10.1016/j.jinf.2022.02.013
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  10. Article: Rheumatoid Arthritis with Generalized Lymphadenopathy Mimicking Lymphoma on Positron Emission Tomography/Computed Tomography with

    Filippi, Luca / Caruso, Gianluca / Bagni, Oreste / Ciacciarelli, Marco / Polidoro, Alessandro / Iuliano, Luigi

    Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India

    2021  Volume 36, Issue 4, Page(s) 449–450

    Abstract: A 42-year-old male presented with weight loss and progressively increasing pain and swelling in joints over the past 3 months. Contrast-enhanced computed tomography (CT) demonstrated pleuropulmonary opacities and supra/infradiaphragmatic lymph nodes ... ...

    Abstract A 42-year-old male presented with weight loss and progressively increasing pain and swelling in joints over the past 3 months. Contrast-enhanced computed tomography (CT) demonstrated pleuropulmonary opacities and supra/infradiaphragmatic lymph nodes enlargement. Positron emission tomography (PET/CT) with
    Language English
    Publishing date 2021-12-15
    Publishing country India
    Document type Journal Article
    ZDB-ID 2181722-4
    ISSN 0974-0244 ; 0972-3919
    ISSN (online) 0974-0244
    ISSN 0972-3919
    DOI 10.4103/ijnm.ijnm_57_21
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