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  1. Book ; Thesis: Amyotrophe Lateralsklerose

    Hübers, Annemarie

    Pathogenese und phänotypische Varianten

    2016  

    Author's details von Annemarie Hübers
    Language German ; English
    Size 43 Blätter, 40 verschieden gezählte Blätter, Illustrationen, Diagramme, 30 cm
    Publishing place Ulm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Habilitationsschrift, Universität Ulm, 2016
    Note Enthält Sonderabdrucke aus Zeitschrift in englischer Sprache
    HBZ-ID HT019806976
    Database Catalogue ZB MED Medicine, Health

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  2. Article: Similarités entre sclérose latérale amyotrophique et démence frontotemporale.

    Hübers, Annemarie

    Revue medicale suisse

    2023  Volume 19, Issue 824, Page(s) 820–821

    Abstract: Frontotemporal dementia (FTD) is characterized by degeneration of the frontal and temporal lobes. Classic symptoms include behavioural alterations and executive dysfunction. Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease ... ...

    Title translation Similarities between amyotrophic lateral sclerosis and frontotemporal dementia.
    Abstract Frontotemporal dementia (FTD) is characterized by degeneration of the frontal and temporal lobes. Classic symptoms include behavioural alterations and executive dysfunction. Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease of the first and second motoneurones, as well as of cortical neurons, presenting with weakness and wasting of the limb, respiratory and bulbar muscles. Accumulation of a mis-localized protein in the neuronal cytoplasma is the main neuropathological marker of ALS but has also been described in certain FTD-variants. Molecules interfering specifically on this level of mis-localization and toxic aggregation may thus represent a very interesting therapeutic approach in both, ALS and FTD.
    MeSH term(s) Humans ; Amyotrophic Lateral Sclerosis ; Frontotemporal Dementia/diagnosis ; Neurodegenerative Diseases
    Language French
    Publishing date 2023-05-03
    Publishing country Switzerland
    Document type English Abstract ; Journal Article
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    DOI 10.53738/REVMED.2023.19.824.820
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Thesis: Physiologische Grundlagen elektromyographischer Spiegelaktivität

    Hübers, Annemarie

    2007  

    Author's details vorgelegt von Annemarie Hübers
    Subject code 612.8
    Language German
    Size III, 116 S., Ill., graph. Darst., 21 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Frankfurt (Main), Univ., Diss., 2008
    HBZ-ID HT016405118
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Are nerve conduction studies altered in functional neurological disorders?

    Sukockienė, Eglė / Assal, Frédéric / Hübers, Annemarie

    Clinical neurophysiology practice

    2022  Volume 7, Page(s) 166–168

    Abstract: Background: Functional neurological disorders represent conditions without a readily identifiable origin or laboratory-supported diagnostic. We report a case of functional neurological disorder, presenting with muscle weakness with alterations in F- ... ...

    Abstract Background: Functional neurological disorders represent conditions without a readily identifiable origin or laboratory-supported diagnostic. We report a case of functional neurological disorder, presenting with muscle weakness with alterations in F-waves on the affected side.
    Case report: A retrospective case review of a patient seen in clinic. Electrophysiological evaluation included nerve conduction studies, including recording of F-waves in lower limbs, and needle EMG. A patchy sensory loss and unilateral muscle weakness of the left lower limb persisted nine days after a 40-year-old female patient developed bilateral lower limb weakness following a laparoscopic surgery. MRI was negative for radicular compression, myelopathy, or lumbosacral plexopathy. F-waves of the peroneal and tibial nerves on the left were absent or of reduced persistence and amplitude compared to the asymptomatic right side.
    Significance: The observation of unilateral alterations of F-wave parameters could be interpreted as an asymmetrical decrease of alpha motor neuron excitability on L4 - S2 segments. In the absence of peripheral nervous system dysfunction or a structural lesion, the results here suggest a central control dysfunction or point to a more complex peripheral role. Further research is necessary to determine the frequency of these findings in a larger group of patients while incorporating other late responses, such as H (Hoffman) reflex, and measures of cortical excitability.
    Language English
    Publishing date 2022-06-02
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2467-981X
    ISSN (online) 2467-981X
    DOI 10.1016/j.cnp.2022.05.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Case Series of Acute Peripheral Neuropathies in Individuals Who Received COVID-19 Vaccination.

    Sukockienė, Eglė / Breville, Gautier / Fayolle, Damien / Nencha, Umberto / Uginet, Marjolaine / Hübers, Annemarie

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 3

    Abstract: Background and ... ...

    Abstract Background and Objectives
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Humans ; Middle Aged ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Drug-Related Side Effects and Adverse Reactions ; Pandemics ; Peripheral Nervous System Diseases/etiology ; SARS-CoV-2 ; Vaccination/adverse effects
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2023-03-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59030501
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Management of patients with generalised myasthenia gravis and COVID-19: four case reports.

    Hübers, Annemarie / Lascano, Agustina M / Lalive, Patrice H

    Journal of neurology, neurosurgery, and psychiatry

    2020  Volume 91, Issue 10, Page(s) 1124–1125

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Lambert-Eaton Myasthenic Syndrome ; Myasthenia Gravis ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-10
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 3087-9
    ISSN 1468-330X ; 0022-3050
    ISSN (online) 1468-330X
    ISSN 0022-3050
    DOI 10.1136/jnnp-2020-323565
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Case Series of Acute Peripheral Neuropathies in Individuals Who Received COVID-19 Vaccination

    Eglė Sukockienė / Gautier Breville / Damien Fayolle / Umberto Nencha / Marjolaine Uginet / Annemarie Hübers

    Medicina, Vol 59, Iss 501, p

    2023  Volume 501

    Abstract: Background and Objectives : Vaccination has been critical to managing the COVID-19 pandemic. Autoimmunity of the nervous system, especially among a select set of high-risk groups, can be triggered or enhanced by the contents of vaccines. Here, we report ... ...

    Abstract Background and Objectives : Vaccination has been critical to managing the COVID-19 pandemic. Autoimmunity of the nervous system, especially among a select set of high-risk groups, can be triggered or enhanced by the contents of vaccines. Here, we report a case series of acute peripheral neuropathies following vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We report on 11 patients (range: 30–90 years old) who presented at our center between January 2021 and February 2022. Methods : We obtained the patients’ history and performed clinical neurological examination and electromyoneurography on all subjects. If necessary, magnetic resonance imaging and laboratory testing, including cerebrospinal fluid analysis and specific antibody testing, were performed. Results : Patients presented with peripheral neuropathies of acute onset between 1 and 40 days after vaccination with different types of COVID-19 vaccines. Most cases (9/11) resolved with a rapid, complete or partial recovery. Conclusions : We found acute peripheral neuropathies in a set of individuals after they received vaccines against SARS-CoV-2. Albeit our observation shows that during extensive vaccination programs, negative side effects on the peripheral nervous system might occur, most of them showed benign clinical evolution. Thus, potential side effects should not hinder the prescription of vaccines. More extensive studies are needed to elucidate populations at risk of developing peripheral neuropathies and mechanisms of autoimmune response in the nervous system.
    Keywords vaccination ; COVID-19 ; neuropathy ; Guillain–Barré syndrome ; Parsonage–Turner syndrome ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Mutation of the

    Hübers, Annemarie / Huppertz, Hans-Jürgen / Wortmann, Saskia B / Kassubek, Jan

    Movement disorders clinical practice

    2019  Volume 7, Issue 1, Page(s) 88–90

    Language English
    Publishing date 2019-11-07
    Publishing country United States
    Document type Case Reports
    ISSN 2330-1619
    ISSN (online) 2330-1619
    DOI 10.1002/mdc3.12855
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Crampes musculaires.

    Fayolle, Damien / Théaudin, Marie / Ochsner, François / Echaniz-Laguna, Andoni / Magy, Laurent / Vicino, Alex / Hübers, Annemarie

    Revue medicale suisse

    2022  Volume 18, Issue 779, Page(s) 785–788

    Abstract: Muscle cramps are very common and can reduce quality of life. There are multiple causes, including some physiological conditions, metabolic, endocrine, vascular disorders or neuromuscular diseases. Adequate management first requires differentiating ... ...

    Title translation Muscle cramps.
    Abstract Muscle cramps are very common and can reduce quality of life. There are multiple causes, including some physiological conditions, metabolic, endocrine, vascular disorders or neuromuscular diseases. Adequate management first requires differentiating cramps from other muscular phenomena. In most cases, the investigations are limited to a comprehensive history and clinical examination, but a biological, radiological and/or electrophysiological work-up may be useful. Treatment, when needed, is most often symptomatic and is unfortunately based on little evidence.
    MeSH term(s) Humans ; Muscle Cramp/diagnosis ; Muscle Cramp/etiology ; Muscle Cramp/therapy ; Quality of Life ; Vascular Diseases/complications
    Language French
    Publishing date 2022-04-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    DOI 10.53738/REVMED.2022.18.779.785
    Database MEDical Literature Analysis and Retrieval System OnLINE

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