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  1. Article ; Online: Management of the airway and lung isolation for thoracic surgery during the COVID-19 pandemic.

    Greenhalgh, D

    Anaesthesia

    2020  Volume 75, Issue 11, Page(s) 1548

    MeSH term(s) Airway Management/methods ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; Thoracic Surgical Procedures/methods
    Keywords covid19
    Language English
    Publishing date 2020-06-11
    Publishing country England
    Document type Letter
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/anae.15167
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 388: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: D-dimer and platelet aggregation and peripheral arterial disease.

    Greenhalgh, R

    European heart journal

    2002  Volume 23, Issue 16, Page(s) 1241–1242

    MeSH term(s) Fibrin Fibrinogen Degradation Products/analysis ; Humans ; Intermittent Claudication/blood ; Peripheral Vascular Diseases/blood ; Platelet Aggregation ; Thrombosis/blood
    Chemical Substances Fibrin Fibrinogen Degradation Products ; fibrin fragment D
    Language English
    Publishing date 2002-08
    Publishing country England
    Document type Comment ; Editorial
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1053/euhj.2002.3226
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1563: Show issues Location:
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  3. Article ; Online: Impact of tetravalent dengue vaccination with screening, ADE, and altered infectivity on single-serotype dengue and Zika transmission.

    Kribs, Christopher / Greenhalgh, David

    Journal of mathematical biology

    2023  Volume 86, Issue 5, Page(s) 85

    Abstract: Acquired immunity to a dengue virus serotype (whether by infection or the only licensed dengue vaccine) can produce antibody-dependent enhancement (ADE) in later infections with another dengue serotype, resulting in higher viral loads and more severe ... ...

    Abstract Acquired immunity to a dengue virus serotype (whether by infection or the only licensed dengue vaccine) can produce antibody-dependent enhancement (ADE) in later infections with another dengue serotype, resulting in higher viral loads and more severe symptoms such as dengue hemorrhagic fever, unless the person already has immunity to multiple dengue serotypes. Screening to confirm dengue seropositivity is therefore recommended before vaccination. Recent studies suggest that the closely-related Zika virus may also interact with dengue through ADE. This study uses a mathematical model to evaluate the likely impact of imperfect screening and dengue vaccination on the spread of both viruses in a population where only one dengue serotype circulates, although the vaccine may take against any or all of the four recognized serotypes. Analysis focuses on the reproductive numbers of the viruses. Results indicate that vaccination increases the spread of Zika through induced ADE, while its impact on the spread of dengue depends on screening specificity and serotype-specific vaccine efficacies, as well as the intensity of ADE. Numerical analysis identifies the roles played by age-in and catch-up vaccination as well as screening characteristics and prior dengue exposure.
    MeSH term(s) Humans ; Dengue ; Zika Virus ; Dengue Virus ; Serogroup ; Antibodies, Viral ; Antibody-Dependent Enhancement ; Zika Virus Infection/prevention & control ; Vaccines ; Vaccination
    Chemical Substances Antibodies, Viral ; Vaccines
    Language English
    Publishing date 2023-04-29
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 187101-8
    ISSN 1432-1416 ; 0303-6812
    ISSN (online) 1432-1416
    ISSN 0303-6812
    DOI 10.1007/s00285-023-01915-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Management of the airway and lung isolation for thoracic surgery during the COVID‐19 pandemic

    Greenhalgh, D.

    Anaesthesia

    2020  Volume 75, Issue 11, Page(s) 1548–1548

    Keywords Anesthesiology and Pain Medicine ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/anae.15167
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Zs.A 388: Show issues Location:
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  6. Book: Einführung in die evidence based medicine

    Greenhalgh, Trisha

    kritische Beurteilung klinischer Studien als Basis einer rationalen Medizin

    2003  

    Title translation How to read a paper
    Title variant Einführung in die evidence-based medicine
    Author's details Trisha Greenhalgh
    Keywords Research ; Clinical Medicine ; Reading ; Evidenz-basierte Medizin
    Subject Evidence-based medicine ; Gutachtenbasierte Medizin ; Evidenzbasierte Medizin
    Language German
    Size 272 S. : graph. Darst.
    Edition 2., vollst. überarb. Aufl.
    Publisher Huber
    Publishing place Bern u.a.
    Publishing country Switzerland
    Document type Book
    Note Aus dem Engl. übers.
    New title Ab 3. Aufl. u.d.T. Greenhalgh, Trisha: Einführung in die evidenzbasierte Medizin
    HBZ-ID HT013619377
    ISBN 3-456-83926-X ; 978-3-456-83926-4
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2003 A 2308 order for loan Magazin

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  7. Article ; Online: Optimizing the timing of renal replacement therapy in burn patients with acute kidney injury.

    Tsotsolis, Stavros / Lavrentieva, Athina / Greenhalgh, David

    Burns : journal of the International Society for Burn Injuries

    2023  Volume 49, Issue 2, Page(s) 247–260

    Abstract: Acute kidney injury is a common complication in burn ICU patients and is associated with a high mortality rate. The optimal timing for starting renal replacement therapy (RRT) remains unknown; there is no established universal definition for early and ... ...

    Abstract Acute kidney injury is a common complication in burn ICU patients and is associated with a high mortality rate. The optimal timing for starting renal replacement therapy (RRT) remains unknown; there is no established universal definition for early and late RRT initiation. The aims of the present narrative review are to briefly analyze the available recently published data on the timing of initiation of RRT in critically ill patients and to discuss the optimal timing of RRT in critically ill burn patients with acute kidney injury. When considering renal replacement therapy for acute kidney injury patients, physicians face the dilemma of balancing the hazards of starting too early, exposing patient to an unnecessary therapy with possible complications and costs related to treatment, and preventing a significant proportion of patients from spontaneous recovery of their renal function against the potential life-threatening harm of initiating RRT) too late. Evidence suggests that with appropriate care up to 80% of burn patients experience recovery of kidney function and the need for RRT seems to be very rare after hospital discharge. In the absence of life-threatening complications, the optimal time and thresholds for starting RRT in burn patients are uncertain. High heterogeneity exists between studies on RRT timing in burn patients.
    MeSH term(s) Humans ; Critical Illness/therapy ; Burns/complications ; Renal Replacement Therapy ; Continuous Renal Replacement Therapy ; Acute Kidney Injury/therapy
    Language English
    Publishing date 2023-01-16
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 197308-3
    ISSN 1879-1409 ; 0305-4179
    ISSN (online) 1879-1409
    ISSN 0305-4179
    DOI 10.1016/j.burns.2023.01.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1250: Show issues Location:
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  9. Article ; Online: Use of Cultured Epithelial Autograft in Conjunction with Biodegradable Temporizing Matrix in Massive Burns: A Case Series.

    Heard, Jason / Sen, Soman / Greenhalgh, David / Palmieri, Tina / Romanowski, Kathleen

    Journal of burn care & research : official publication of the American Burn Association

    2023  Volume 44, Issue 6, Page(s) 1434–1439

    Abstract: Intensive care for massively burn patients has increased survival and highlights the need for a solution to the problem of insufficient donor sites for autologous skin coverage. In this case series, we present 10 patients with average burn size of 81% ... ...

    Abstract Intensive care for massively burn patients has increased survival and highlights the need for a solution to the problem of insufficient donor sites for autologous skin coverage. In this case series, we present 10 patients with average burn size of 81% TBSA and mean age of 24 years old, who underwent burn excision followed by either immediate or delayed biodegradable temporizing matrix (BTM) placement. After an integration period, the BTM was delaminated either the day before or immediately prior to placement of cultured epithelial autografts over a widely meshed (4:1 or 6:1) split thickness skin graft. One patient had cultured epithelial autografts alone, without split thickness skin graft, placed on integrated BTM and had successful take. Seven patients survived to discharge and had average 95% wound closure at 135 ± 35 days. The patients had on average 10.4 total operations and 8.7 excision and grafting operations. Five patients had complications related to the BTM requiring removal or replacement including three fungal infections, one bacterial infection and one with bleeding and a large clot burden. In conclusion, this surgical strategy is a viable option for patients with massive burns and insufficient donor for autologous skin grafting.
    MeSH term(s) Humans ; Young Adult ; Adult ; Burns/surgery ; Autografts/surgery ; Transplantation, Autologous ; Skin ; Skin Transplantation
    Language English
    Publishing date 2023-05-24
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2224246-6
    ISSN 1559-0488 ; 1559-047X
    ISSN (online) 1559-0488
    ISSN 1559-047X
    DOI 10.1093/jbcr/irad076
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6223: Show issues Location:
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  10. Article ; Online: Strategies for the prevention of peri-operative transoesophageal echocardiography-related complications.

    Ashworth, A D / Greenhalgh, D L

    Anaesthesia

    2019  Volume 75, Issue 1, Page(s) 3–6

    MeSH term(s) Anesthesia, Cardiac Procedures ; Critical Care ; Echocardiography, Transesophageal ; Humans ; Prospective Studies
    Language English
    Publishing date 2019-07-04
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/anae.14772
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 388: Show issues Location:
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