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Article ; Online: Managing COVID-19 disease in pediatric patients.

Mon, Ei Ye / Mandelia, Yamini

2021

Abstract: Children are less likely to be infected with SARS-CoV-2 than adults and often have a milder course of COVID-19 disease and a lower case fatality rate. Children account for an estimated 1% to 8% of those diagnosed with COVID-19. Even so, preschool-aged ... ...

Abstract	Children are less likely to be infected with SARS-CoV-2 than adults and often have a milder course of COVID-19 disease and a lower case fatality rate. Children account for an estimated 1% to 8% of those diagnosed with COVID-19. Even so, preschool-aged children, infants, and children with underlying health conditions may still be at risk for severe disease and complications. Unique aspects of COVID-19 presentation and disease course in children and possible vertical transmission to newborns from COVID-19-positive mothers are discussed.
Keywords	covid19
Language	English
Publishing date	2021-02-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	639116-3
ISSN	1939-2869 ; 0891-1150
ISSN (online)	1939-2869
ISSN	0891-1150
DOI	10.3949/ccjm.87a.ccc022
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Article: Managing COVID-19 Iinfection in pediatric patients

Mon, Ei Ye / Mandelia, Yamini

Cleve Clin J Med

Abstract: Children are less likely to be infected with SARS-CoV-2 than adults and often have a milder course of illness and a lower case fatality rate Children account for an estimated 1% to 5% of those diagnosed with COVID-19 (1) Even so, pre-school-aged children, ...

Abstract	Children are less likely to be infected with SARS-CoV-2 than adults and often have a milder course of illness and a lower case fatality rate Children account for an estimated 1% to 5% of those diagnosed with COVID-19 (1) Even so, pre-school-aged children, infants, and children with underlying health conditions may still be at risk for severe disease and complications (2) Unique aspects of COVID-19 presentation and course in children and possible vertical transmission to newborns from COVID-19-positive mothers are discussed
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #256636
Database	COVID19

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Article: Managing COVID-19 disease in pediatric patients

Mon, Ei Ye / Mandelia, Yamini

Clevel. clin. j. med

Abstract: Children are less likely to be infected with SARS-CoV-2 than adults and often have a milder course of COVID-19 disease and a lower case fatality rate. Children account for an estimated 1% to 5% of those diagnosed with COVID-19. Even so, preschool-aged ... ...

Abstract	Children are less likely to be infected with SARS-CoV-2 than adults and often have a milder course of COVID-19 disease and a lower case fatality rate. Children account for an estimated 1% to 5% of those diagnosed with COVID-19. Even so, preschool-aged children, infants, and children with underlying health conditions may still be at risk for severe disease and complications. Unique aspects of COVID-19 presentation and disease course in children and possible vertical transmission to newborns from COVID-19-positive mothers are discussed.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #32393595
Database	COVID19

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Article: Anti-hepatitis B activities of Myanmar medicinal plants: a narrative review of current evidence.

Linn, Ye Htut / Ei, Win Win / Myint, Lwin Mon Mon / Lwin, Khin Maung

Virusdisease

2021 Volume 32, Issue 3, Page(s) 446–466

Abstract: Hepatitis B is one of the major burdens for health services and is the leading cause of morbidity and mortality from cirrhosis of liver and hepatocellular carcinoma. Current treatment strategies using nucleos(t)ide analogue reverse-transcriptase ... ...

Abstract	Hepatitis B is one of the major burdens for health services and is the leading cause of morbidity and mortality from cirrhosis of liver and hepatocellular carcinoma. Current treatment strategies using nucleos(t)ide analogue reverse-transcriptase inhibitors or interferons are targeted for the long-term suppression of hepatitis B DNA. However, functional cure of hepatitis B infection (HBsAg clearance) was difficult to attain with such treatments. Therefore, new treatment strategies or innovative treatments are urgently needed. The new treatments should focus on the potential therapeutic targets such as covalently closed circular DNA which may be important for the HBsAg clearance. Plant based medicines have been used in different traditional medicine practices and these natural products/compounds serve as a good source of information or clues for use in drug discovery and design. Many natural products were found to be effective against hepatitis B virus and some even have better therapeutic activities than currently used compounds. This review summarizes the current evidence of Myanmar medicinal plants in basic and clinical research which shows promising potential for the development of novel therapeutic agents for the treatment of hepatitis B.
Language	English
Publishing date	2021-07-14
Publishing country	India
Document type	Journal Article ; Review
ZDB-ID	2846993-8
ISSN	2347-3517 ; 2347-3584
ISSN (online)	2347-3517
ISSN	2347-3584
DOI	10.1007/s13337-021-00714-2
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Article: Anti-hepatitis B activities of Myanmar medicinal plants: a narrative review of current evidence

Linn, Ye Htut / Ei, Win Win / Myint, Lwin Mon Mon / Lwin, Khin Maung

Virusdisease. 2021 Sept., v. 32, no. 3

2021

Abstract	Hepatitis B is one of the major burdens for health services and is the leading cause of morbidity and mortality from cirrhosis of liver and hepatocellular carcinoma. Current treatment strategies using nucleos(t)ide analogue reverse-transcriptase inhibitors or interferons are targeted for the long-term suppression of hepatitis B DNA. However, functional cure of hepatitis B infection (HBsAg clearance) was difficult to attain with such treatments. Therefore, new treatment strategies or innovative treatments are urgently needed. The new treatments should focus on the potential therapeutic targets such as covalently closed circular DNA which may be important for the HBsAg clearance. Plant based medicines have been used in different traditional medicine practices and these natural products/compounds serve as a good source of information or clues for use in drug discovery and design. Many natural products were found to be effective against hepatitis B virus and some even have better therapeutic activities than currently used compounds. This review summarizes the current evidence of Myanmar medicinal plants in basic and clinical research which shows promising potential for the development of novel therapeutic agents for the treatment of hepatitis B.
Keywords	Hepatitis B virus ; biomedical research ; chemical bonding ; circular DNA ; drugs ; hepatitis B ; hepatoma ; information sources ; liver cirrhosis ; morbidity ; mortality ; therapeutics ; traditional medicine ; Myanmar
Language	English
Dates of publication	2021-09
Size	p. 446-466.
Publishing place	Springer India
Document type	Article
Note	Review
ZDB-ID	2846993-8
ISSN	2347-3517 ; 2347-3584
ISSN (online)	2347-3517
ISSN	2347-3584
DOI	10.1007/s13337-021-00714-2
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Seroprevalence and associated risk factors of Toxoplasma gondii infection among slaughterhouse workers in Yangon Region, Myanmar: A cross-sectional study.

Sint, Nay Hein / Htun, Ye Minn / Win, Tun Tun / Mon, Aye Sandar / Lwin, Thant Zaw / Maung, Lwin Oo / Win, Pyae Sone / Naing, Kaung Myat / Zaw, Thet Paing / Naing, Pyae Hpone / Tun, Sai Nyan Lin / Kyaw, Aung Aye / Wunna, Kyaw / Su, Khine Khine / Tun, Kyaw Myo

PloS one

2023 Volume 18, Issue 4, Page(s) e0284352

Abstract: Background: Toxoplasmosis, having the significant consequences affecting mortality and quality of life, is still prevalent in various places throughout the world. The major gap in surveillance for Toxoplasma gondii infection among high-risk population, ... ...

Abstract	Background: Toxoplasmosis, having the significant consequences affecting mortality and quality of life, is still prevalent in various places throughout the world. The major gap in surveillance for Toxoplasma gondii infection among high-risk population, slaughterhouse workers, is an obstacle for the effective policies formulation to reduce the burden of toxoplasmosis in Myanmar. Therefore, this study aimed to assess the seroprevalence of toxoplasmosis and associated factors of seropositivity among slaughterhouse workers in Yangon Region, Myanmar. Methods: A cross-sectional study that was conducted from June to November 2020 included 139 slaughterhouse workers involving at five main slaughterhouses under Yangon City Development Committee, Myanmar. The presence of IgG and IgM anti-T. gondii antibodies in serum was detected using the OnSite Toxo IgG/IgM Combo Rapid Test. A face-to-face interview was also performed using pretested structured questionnaires to obtain the detail histories: sociodemographic characteristics, level of knowledge, occupational factors, and environmental factors related to T. gondii infection. Bivariate logistic regression was used to determine the factors associated with T. gondii infection. Results: Of all participants, the overall seroprevalence of anti-T. gondii was 43.9% (95% CI: 35.5-52.5%), of whom 98.4% (95% CI: 91.2-100.0%) were reactive only for IgG antibody and 1.6% (95% CI: 0.0-8.8%) were reactive for IgG and IgM antibodies. The significant factors associated with the seropositivity of T. gondii antibodies were blood transfusion history (OR: 5.74, 95% CI: 1.17-28.09), low level of knowledge (OR: 2.91, 95% CI: 1.46-5.83), contact with animal organs, muscles or blood (OR: 14.29, 95% CI: 1.83-111.51), and animals most frequently slaughtered (cattle) (OR: 3.22, 95% CI: 1.16-8.93). Conclusions: A high seroprevalence of toxoplasmosis was detected among slaughterhouse workers in Yangon Region and it raises a significant public health concern. Therefore, providing health education regarding toxoplasmosis, enforcement of personal hygiene practices in workplaces, the establishment of training for occupational hygiene, and commencement of the risk assessment and serological screening for toxoplasmosis are crucial to curtail the prevalence of T. gondii infection among slaughterhouse workers.
MeSH term(s)	Animals ; Cattle ; Toxoplasma ; Cross-Sectional Studies ; Abattoirs ; Seroepidemiologic Studies ; Myanmar/epidemiology ; Quality of Life ; Antibodies, Protozoan ; Toxoplasmosis ; Risk Factors ; Immunoglobulin G ; Immunoglobulin M
Chemical Substances	Antibodies, Protozoan ; Immunoglobulin G ; Immunoglobulin M
Language	English
Publishing date	2023-04-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0284352
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Seroprevalence and associated risk factors of Toxoplasma gondii infection among slaughterhouse workers in Yangon Region, Myanmar

Nay Hein Sint / Ye Minn Htun / Tun Tun Win / Aye Sandar Mon / Thant Zaw Lwin / Lwin Oo Maung / Pyae Sone Win / Kaung Myat Naing / Thet Paing Zaw / Pyae Hpone Naing / Sai Nyan Lin Tun / Aung Aye Kyaw / Kyaw Wunna / Khine Khine Su / Kyaw Myo Tun

PLoS ONE, Vol 18, Iss

A cross-sectional study

2023 Volume 4

Abstract: Background Toxoplasmosis, having the significant consequences affecting mortality and quality of life, is still prevalent in various places throughout the world. The major gap in surveillance for Toxoplasma gondii infection among high-risk population, ... ...

Abstract	Background Toxoplasmosis, having the significant consequences affecting mortality and quality of life, is still prevalent in various places throughout the world. The major gap in surveillance for Toxoplasma gondii infection among high-risk population, slaughterhouse workers, is an obstacle for the effective policies formulation to reduce the burden of toxoplasmosis in Myanmar. Therefore, this study aimed to assess the seroprevalence of toxoplasmosis and associated factors of seropositivity among slaughterhouse workers in Yangon Region, Myanmar. Methods A cross-sectional study that was conducted from June to November 2020 included 139 slaughterhouse workers involving at five main slaughterhouses under Yangon City Development Committee, Myanmar. The presence of IgG and IgM anti-T. gondii antibodies in serum was detected using the OnSite Toxo IgG/IgM Combo Rapid Test. A face-to-face interview was also performed using pretested structured questionnaires to obtain the detail histories: sociodemographic characteristics, level of knowledge, occupational factors, and environmental factors related to T. gondii infection. Bivariate logistic regression was used to determine the factors associated with T. gondii infection. Results Of all participants, the overall seroprevalence of anti-T. gondii was 43.9% (95% CI: 35.5–52.5%), of whom 98.4% (95% CI: 91.2–100.0%) were reactive only for IgG antibody and 1.6% (95% CI: 0.0–8.8%) were reactive for IgG and IgM antibodies. The significant factors associated with the seropositivity of T. gondii antibodies were blood transfusion history (OR: 5.74, 95% CI: 1.17–28.09), low level of knowledge (OR: 2.91, 95% CI: 1.46–5.83), contact with animal organs, muscles or blood (OR: 14.29, 95% CI: 1.83–111.51), and animals most frequently slaughtered (cattle) (OR: 3.22, 95% CI: 1.16–8.93). Conclusions A high seroprevalence of toxoplasmosis was detected among slaughterhouse workers in Yangon Region and it raises a significant public health concern. Therefore, providing health education regarding ...
Keywords	Medicine ; R ; Science ; Q
Subject code	630
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Seroprevalence and associated risk factors of Toxoplasma gondii infection among slaughterhouse workers in Yangon Region, Myanmar

PLoS ONE, Vol 18, Iss 4, p e

A cross-sectional study.

2023 Volume 0284352

Abstract	Background Toxoplasmosis, having the significant consequences affecting mortality and quality of life, is still prevalent in various places throughout the world. The major gap in surveillance for Toxoplasma gondii infection among high-risk population, slaughterhouse workers, is an obstacle for the effective policies formulation to reduce the burden of toxoplasmosis in Myanmar. Therefore, this study aimed to assess the seroprevalence of toxoplasmosis and associated factors of seropositivity among slaughterhouse workers in Yangon Region, Myanmar. Methods A cross-sectional study that was conducted from June to November 2020 included 139 slaughterhouse workers involving at five main slaughterhouses under Yangon City Development Committee, Myanmar. The presence of IgG and IgM anti-T. gondii antibodies in serum was detected using the OnSite Toxo IgG/IgM Combo Rapid Test. A face-to-face interview was also performed using pretested structured questionnaires to obtain the detail histories: sociodemographic characteristics, level of knowledge, occupational factors, and environmental factors related to T. gondii infection. Bivariate logistic regression was used to determine the factors associated with T. gondii infection. Results Of all participants, the overall seroprevalence of anti-T. gondii was 43.9% (95% CI: 35.5-52.5%), of whom 98.4% (95% CI: 91.2-100.0%) were reactive only for IgG antibody and 1.6% (95% CI: 0.0-8.8%) were reactive for IgG and IgM antibodies. The significant factors associated with the seropositivity of T. gondii antibodies were blood transfusion history (OR: 5.74, 95% CI: 1.17-28.09), low level of knowledge (OR: 2.91, 95% CI: 1.46-5.83), contact with animal organs, muscles or blood (OR: 14.29, 95% CI: 1.83-111.51), and animals most frequently slaughtered (cattle) (OR: 3.22, 95% CI: 1.16-8.93). Conclusions A high seroprevalence of toxoplasmosis was detected among slaughterhouse workers in Yangon Region and it raises a significant public health concern. Therefore, providing health education regarding ...
Keywords	Medicine ; R ; Science ; Q
Subject code	630
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Sustainability of a mobile phone application-based data reporting system in Myanmar's malaria elimination program: a qualitative study.

Win Han Oo / Kaung Myat Thu / Cutts, Julia C / Win Htike / Kyawt Mon Win / May Chan Oo / Galau, Naw Hkawng / Agius, Paul A / Pyae Phyo Htoon / Kearney, Ellen / Aung Thi / Ye Win Aung / Min Min Thein / Rosecrans, Kathryn / Kyi Tun Lwin / Aung Kyi Min / Fowkes, Freya J I

BMC medical informatics and decision making

2021 Volume 21, Issue 1, Page(s) 285

Abstract: Background: Strengthening surveillance systems to collect near-real-time case-based data plays a fundamental role in achieving malaria elimination in the Greater Mekong Subregion (GMS). With the advanced and widespread use of digital technology, mHealth ...

Abstract	Background: Strengthening surveillance systems to collect near-real-time case-based data plays a fundamental role in achieving malaria elimination in the Greater Mekong Subregion (GMS). With the advanced and widespread use of digital technology, mHealth is increasingly taking a prominent role in malaria surveillance systems in GMS countries, including Myanmar. In Myanmar's malaria elimination program, an mHealth system called Malaria Case-based Reporting (MCBR) has been applied for case-based reporting of malaria data by integrated community malaria volunteers (ICMVs). However, the sustainability of such mHealth systems in the context of existing malaria elimination programs in Myanmar is unknown. Methods: Focus group discussions were conducted with ICMVs and semi-structured in-depth interviews were conducted with malaria program stakeholders from Myanmar's Ministry of Health and Sports and its malaria program implementing partners. Thematic (deductive followed by inductive) analysis was undertaken using a qualitative descriptive approach. Results: Technological and financial constraints such as inadequate internet access, software errors, and insufficient financial resources to support mobile phone-related costs have hampered users' access to MCBR. Poor system integrity, unpredictable reporting outcomes, inadequate human resources for system management, and inefficient user support undermined the perceived quality of the system and user satisfaction, and hence its sustainability. Furthermore, multiple parallel systems with functions overlapping those of MCBR were in use. Conclusions: Despite its effectiveness and efficiency in malaria surveillance, the sustainability of nationwide implementation of MCBR is uncertain. To make it sustainable, stakeholders should deploy a dedicated human workforce with the necessary technical and technological capacities; secure sustainable, long-term funding for implementation of MCBR; find an alternative cost-effective plan for ensuring sustainable system access by ICMVs, such as using volunteer-owned mobile phones for reporting rather than supporting new mobile phones to them; and find a solution to the burden of multiple parallel systems. Trial registration: Not applicable.
MeSH term(s)	Cell Phone ; Humans ; Malaria/epidemiology ; Malaria/prevention & control ; Mobile Applications ; Myanmar/epidemiology ; Research Design
Language	English
Publishing date	2021-10-18
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1472-6947
ISSN (online)	1472-6947
DOI	10.1186/s12911-021-01646-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: BER Analysis Of IEEE802.11n MIMO System Using MMSE And ZF Detectors

Ye Lwin Oo / Su Su Yi Mon / Hla Myo Tun

International Journal of Scientific & Technology Research, Vol 4, Iss 6, Pp 401-

2015 Volume 404

Abstract: Abstract With the increasing demand of higher data rate for telecommunication the IEEE802.11n standard was constituted in 2009. The most important character of the standard is MIMO-OFDM which not only improves the throughput but also the spectrum ... ...

Abstract	Abstract With the increasing demand of higher data rate for telecommunication the IEEE802.11n standard was constituted in 2009. The most important character of the standard is MIMO-OFDM which not only improves the throughput but also the spectrum efficiency and channel capacity. And in wireless communication the role of MIMO detectors plays an important part to remove inter-symbol interference ISI caused by multipath fading channel. In this paper the BER performance of IEEE 802.11n for 3x2 4x2 and 4x3 antennas are compared using MMSE and ZF detectors in Matlab Simulink.
Keywords	Keywords BER ; Detector ; MIMO-OFDM ; Simulink. ; Science ; Q
Language	English
Publishing date	2015-06-01T00:00:00Z
Publisher	IJSTR
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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