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  1. Article: Non-Antimicrobial Adjuvant Strategies to Tackle Biofilm-Related

    Pant, Narayan / Eisen, Damon P

    Antibiotics (Basel, Switzerland)

    2021  Volume 10, Issue 9

    Abstract: Staphylococcus ... ...

    Abstract Staphylococcus aureus
    Language English
    Publishing date 2021-09-01
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics10091060
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Effect of Savirin or Ticagrelor Treatment on the Expression of Commonly Used Reference Genes in

    Pant, Narayan / Rush, Catherine / Warner, Jeffrey / Eisen, Damon P

    Microorganisms

    2023  Volume 11, Issue 2

    Abstract: Reference genes are frequently used for the normalization of quantitative reverse transcriptase PCR (qRTPCR) data in gene expression studies. ...

    Abstract Reference genes are frequently used for the normalization of quantitative reverse transcriptase PCR (qRTPCR) data in gene expression studies.
    Language English
    Publishing date 2023-01-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11020336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Hearing impairment as an unusual presenting sign of

    Gong, Sophie / Sivabalan, Pirathaban / Eisen, Damon P

    BMJ case reports

    2021  Volume 14, Issue 4

    Abstract: Hearing loss is an unusual presenting feature ... ...

    Abstract Hearing loss is an unusual presenting feature of
    MeSH term(s) Cryptococcosis/complications ; Cryptococcosis/diagnosis ; Cryptococcus gattii/isolation & purification ; Hearing Loss/microbiology ; Humans ; Meningoencephalitis/complications ; Meningoencephalitis/diagnosis
    Language English
    Publishing date 2021-04-16
    Publishing country England
    Document type Case Reports ; Journal Article ; Review
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2020-239040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Effect of savirin in the prevention of biofilm-related

    Pant, Narayan / Miranda-Hernandez, Socorro / Rush, Catherine / Warner, Jeffrey / Eisen, Damon P

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 989417

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2022-09-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.989417
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Non-Antimicrobial Adjuvant Therapy Using Ticagrelor Reduced Biofilm-Related

    Pant, Narayan / Miranda-Hernandez, Socorro / Rush, Catherine / Warner, Jeffrey / Eisen, Damon P

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 927783

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2022-07-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.927783
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: In vitro effect of synovial fluid from patients undergoing arthroplasty surgery on MRSA biofilm formation.

    Pant, Narayan / Wallis, Steven C / Roberts, Jason A / Eisen, Damon P

    The Journal of antimicrobial chemotherapy

    2022  Volume 77, Issue 4, Page(s) 1041–1044

    Abstract: Background: Bacterial biofilm is a key component in the pathogenesis of prosthetic joint infection (PJI). Synovial fluid has been shown to have inhibitory activity against planktonic bacteria. However, the contribution of synovial fluid in prevention of ...

    Abstract Background: Bacterial biofilm is a key component in the pathogenesis of prosthetic joint infection (PJI). Synovial fluid has been shown to have inhibitory activity against planktonic bacteria. However, the contribution of synovial fluid in prevention of Staphylococcus aureus (including MRSA) planktonic and biofilm forms is unknown.
    Objectives: To test the antibacterial and antibiofilm activities of synovial fluid, including that containing cefazolin, against MSSA and MRSA.
    Materials and methods: We determined the antiplanktonic and antibiofilm activities of synovial fluid collected from patients given preoperative cefazolin while undergoing elective arthroplasty surgery. MICs of cefazolin were determined for planktonic and biofilm cultures of biofilm-forming strains of MSSA and MRSA.
    Results: Synovial fluid inhibited planktonic and biofilm cultures of MSSA and MRSA. Cefazolin-containing synovial fluid had greater antibacterial and antibiofilm activities than the same cefazolin concentration in glucose LB (GLB) broth. MSSA and MRSA MICs of cefazolin suspended in synovial fluid were 0.7 mg/L. The MICs of cefazolin diluted in GLB broth were higher, measuring 1.4 mg/L for MSSA and 23 mg/L for MRSA.
    Conclusions: Synovial fluid containing cefazolin inhibited biofilm- and planktonic-state MRSA cultures. This may explain the apparent effect of cefazolin in the prevention of MRSA PJI.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Arthroplasty/adverse effects ; Biofilms ; Cefazolin/pharmacology ; Humans ; Methicillin-Resistant Staphylococcus aureus ; Microbial Sensitivity Tests ; Staphylococcal Infections/microbiology ; Synovial Fluid
    Chemical Substances Anti-Bacterial Agents ; Cefazolin (IHS69L0Y4T)
    Language English
    Publishing date 2022-01-19
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkab497
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1197: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 124: Show issues

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  7. Article ; Online: Editorial Commentary: Shall We Disregard Mannose-Binding Lectin Modification in the Future Because We Cannot Prevent Sepsis With This Molecule?

    Eisen, Damon P

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2015  Volume 61, Issue 5, Page(s) 704–706

    MeSH term(s) Female ; Genetic Predisposition to Disease/genetics ; Humans ; Male ; Mannose-Binding Lectin/genetics ; Sepsis/epidemiology ; Sepsis/genetics
    Chemical Substances Mannose-Binding Lectin
    Language English
    Publishing date 2015-09-01
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/civ380
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1505: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 480: Show issues

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  8. Article: Tropical Australian Health-Data Linkage Shows Excess Mortality Following Severe Infectious Disease Is Present in the Short-Term and Long-Term after Hospital Discharge.

    Adegboye, Oyelola A / McBryde, Emma S / Eisen, Damon P

    Healthcare (Basel, Switzerland)

    2021  Volume 9, Issue 7

    Abstract: Background: In this study, we aimed to assess the risk factors associated with mortality due to an infectious disease over the short-, medium-, and long-term based on a data-linkage study for patients discharged from an infectious disease unit in North ... ...

    Abstract Background: In this study, we aimed to assess the risk factors associated with mortality due to an infectious disease over the short-, medium-, and long-term based on a data-linkage study for patients discharged from an infectious disease unit in North Queensland, Australia, between 2006 and 2011.
    Methods: Age-sex standardised mortality rates (SMR) for different subgroups were estimated, and the Kaplan-Meier method was used to estimate and compare the survival experience among different groups.
    Results: Overall, the mortality rate in the hospital cohort was higher than expected in comparison with the Queensland population (SMR: 15.3, 95%CI: 14.9-15.6). The long-term mortality risks were significantly higher for severe infectious diseases than non-infectious diseases for male sex, Indigenous, residential aged care and elderly individuals.
    Conclusion: In general, male sex, Indigenous status, age and comorbidity were associated with an increased hazard for all-cause deaths.
    Language English
    Publishing date 2021-07-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare9070901
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A systematic review on the health outcomes associated with non-endocarditis manifestations of chronic Q fever.

    Manchal, Naveen / Adegboye, Oyelola A / Eisen, Damon P

    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

    2020  Volume 39, Issue 12, Page(s) 2225–2233

    Abstract: The aim of this study was to systematically review the non-endocarditis manifestations of chronic Q fever and understand the significance of non-specific symptoms like pain and fatigue in chronic endovascular, osteomyelitis and abscess due to chronic Q ... ...

    Abstract The aim of this study was to systematically review the non-endocarditis manifestations of chronic Q fever and understand the significance of non-specific symptoms like pain and fatigue in chronic endovascular, osteomyelitis and abscess due to chronic Q fever. We performed a systematic review using Pub Med (the National Library of Medicine (NLM)) and Scopus databases. All studies in English on chronic Q fever that listed clinical manifestations other than infective endocarditis (IE) and chronic fatigue syndrome (CFS). Meta-analysis was carried out to investigate the effects of patient's health outcomes (pain, fatigue, the need for surgery and mortality) on vascular infections, osteomyelitis and abscess. Among cases not presenting as IE or CFS, vascular infections and osteomyelitis were the most common chronic Q fever disease manifestations. There were distinct regional patterns of disease. Compared with infective endocarditis, these are significantly associated with increased risk of pain: osteomyelitis (relative risk (RR) = 4.13, 95% confidence interval (CI) 3.36-5.07), abscess (RR = 3.59, 95% CI 3.28-3.93) and vascular infection (RR = 2.46, 95% CI 1.99-3.03). The strongest significant association was observed between osteomyelitis and pain. There was no significant association between fatigue and these manifestations. Clinicians have to be aware of uncommon manifestations of chronic Q fever as they present with non-specific symptoms and are significantly associated with increased risk of morbidity and mortality. The findings emphasise the need to investigate patients with positive chronic Q fever serology presenting with acute or chronic pain for possible underlying complications.
    MeSH term(s) Coxiella burnetii ; Endocarditis/etiology ; Fatigue Syndrome, Chronic/etiology ; Humans ; Osteomyelitis/etiology ; Outcome Assessment, Health Care ; Q Fever/complications
    Language English
    Publishing date 2020-07-13
    Publishing country Germany
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 603155-9
    ISSN 1435-4373 ; 0934-9723 ; 0722-2211
    ISSN (online) 1435-4373
    ISSN 0934-9723 ; 0722-2211
    DOI 10.1007/s10096-020-03931-7
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1732: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Tropical Australian Health-Data Linkage Shows Excess Mortality Following Severe Infectious Disease Is Present in the Short-Term and Long-Term after Hospital Discharge

    Oyelola A. Adegboye / Emma S. McBryde / Damon P. Eisen

    Healthcare, Vol 9, Iss 901, p

    2021  Volume 901

    Abstract: Background: In this study, we aimed to assess the risk factors associated with mortality due to an infectious disease over the short-, medium-, and long-term based on a data-linkage study for patients discharged from an infectious disease unit in North ... ...

    Abstract Background: In this study, we aimed to assess the risk factors associated with mortality due to an infectious disease over the short-, medium-, and long-term based on a data-linkage study for patients discharged from an infectious disease unit in North Queensland, Australia, between 2006 and 2011. Methods: Age-sex standardised mortality rates (SMR) for different subgroups were estimated, and the Kaplan-Meier method was used to estimate and compare the survival experience among different groups. Results: Overall, the mortality rate in the hospital cohort was higher than expected in comparison with the Queensland population (SMR: 15.3, 95%CI: 14.9–15.6). The long-term mortality risks were significantly higher for severe infectious diseases than non-infectious diseases for male sex, Indigenous, residential aged care and elderly individuals. Conclusion: In general, male sex, Indigenous status, age and comorbidity were associated with an increased hazard for all-cause deaths.
    Keywords sepsis ; mortality ; infectious disease ; data-linkage ; North Queensland ; Medicine ; R
    Language English
    Publishing date 2021-07-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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