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Article ; Online: It's a Start: An Online, On-Demand LGBTQ+ Mental Health Training Session for Providers Nationwide.

Nowaskie, Dustin Z / Werner-Sleva, Stephen B / Jacobs, Amy K

2023 Volume 75, Issue 5, Page(s) 481–484

Abstract: Objective: The purpose of this study was to determine whether an online, on-demand, and publicly accessible mental health training session on care for lesbian, gay, bisexual, transgender, queer, and all sexual-diverse and gender-diverse (LGBTQ+) ... ...

Abstract	Objective: The purpose of this study was to determine whether an online, on-demand, and publicly accessible mental health training session on care for lesbian, gay, bisexual, transgender, queer, and all sexual-diverse and gender-diverse (LGBTQ+) individuals could improve providers' preparedness, attitudes, and knowledge regarding care for LGBTQ+ patients. Methods: Between January and June 2022, participating mental health providers completed the Lesbian, Gay, Bisexual, and Transgender Development of Clinical Skills Scale (LGBT-DOCSS) before and after training. Results: Participants (N=322) represented various mental health specialties and all U.S. regions. LGBT-DOCSS scores significantly increased after training: for overall LGBT-DOCSS, Cohen's d=0.77 (p<0.001); for clinical preparedness, Cohen's d=0.68 (p<0.001); for attitudinal awareness, Cohen's d=0.14 (p=0.014); and for basic knowledge, Cohen's d=0.62 (p<0.001). Conclusions: Although participating mental health providers had improvements in the parameters assessed, small but notable gaps in their LGBTQ+ health awareness and practice remained, suggesting that LGBTQ+ education requires motivated, longitudinal, ongoing, and lifelong learning approaches.
MeSH term(s)	Humans ; Sexual and Gender Minorities ; Female ; Male ; Adult ; Health Personnel/education ; United States ; Mental Health Services ; Clinical Competence ; Attitude of Health Personnel ; Health Knowledge, Attitudes, Practice ; Middle Aged
Language	English
Publishing date	2023-12-21
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1220173-x
ISSN	1557-9700 ; 1075-2730
ISSN (online)	1557-9700
ISSN	1075-2730
DOI	10.1176/appi.ps.20220473
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Article ; Online: Chicago's Citywide COVID-19 Vaccine Equity Program: Protect Chicago Plus.

Johnson, Amy K / Smith, C Scott / Hunt, Bijou / Jacobs, Jacquelyn / Roesch, Pamela

Public health reports (Washington, D.C. : 1974)

2023 Volume 138, Issue 2, Page(s) 218–222

Abstract: Vaccination is one of the most effective strategies to control the spread of COVID-19 and reduce morbidity and mortality; however, rapid and equitable vaccine distribution is required to achieve such outcomes. We conducted a basic interrupted time-series ...

Abstract	Vaccination is one of the most effective strategies to control the spread of COVID-19 and reduce morbidity and mortality; however, rapid and equitable vaccine distribution is required to achieve such outcomes. We conducted a basic interrupted time-series analysis to examine the short-term impacts of a citywide vaccine equity plan, the Protect Chicago Plus (PCP) plan. We compared vaccine coverage in zip codes in Chicago with high COVID-19 vulnerability, as identified from the Chicago COVID-19 Community Vulnerability Index, with coverage in all other zip codes in Chicago. From our analysis, we observed that implementation of PCP coincided with reduced vaccination disparities between Chicago communities with low and high vulnerability indexes over time. In our analysis of vaccination coverage before program implementation, vaccination coverage climbed nearly twice as fast among non-PCP zip codes (0.19% per day) than among PCP zip codes (0.10% per day) or by 0.09 percentage points (
MeSH term(s)	Humans ; Chicago/epidemiology ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Vaccines ; Vaccination ; Vaccination Coverage
Chemical Substances	COVID-19 Vaccines
Language	English
Publishing date	2023-01-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	120953-x
ISSN	1468-2877 ; 0033-3549
ISSN (online)	1468-2877
ISSN	0033-3549
DOI	10.1177/00333549221143093
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Article ; Online: A Community-Informed Approach to COVID-19 Vaccine Roll-Out in Under-served Areas in Chicago.

DiVirgilio, Laura / Boshara, Arianna / Hunt, Bijou R / Jacobs, Jacquelyn / Just, Kate / Johnson, Amy K

Frontiers in public health

2022 Volume 10, Page(s) 863125

Abstract: The availability of the COVID-19 vaccine in the US created an urgent need for strategies to achieve widespread vaccine distribution, but approaches to achieving equitable distribution, including reaching communities of color, varied across the country. ... ...

Abstract	The availability of the COVID-19 vaccine in the US created an urgent need for strategies to achieve widespread vaccine distribution, but approaches to achieving equitable distribution, including reaching communities of color, varied across the country. To add to the knowledge base around targeted vaccine roll-out among underserved communities, the current study presents results from patient vaccination data and staff interviews conducted at Sinai Chicago, a safety-net healthcare system serving under-resourced communities. A total of 11,313 patients received at least one dose of Pfizer or Moderna COVID-19 vaccine between January and October 2021 at a Sinai Chicago facility. The sample was primarily comprised of Hispanic and non-Hispanic Black persons, with a mean age of 47 years, and was split evenly between female and male individuals. Compared to non-Hispanic White persons, Hispanic persons were 1.4 times more likely to have completed the full course of vaccination, while non-Hispanic Black persons were 40% less likely. People ages 18-24 were less likely to be fully vaccinated compared to all other adult age groups. Compared to privately insured persons, publicly insured persons were 40% less likely to have been fully vaccinated. The vaccine roll-out approach focused on educating the community through town halls and targeted messaging to address common myths and misconceptions about the vaccine, as well as developing the necessary infrastructure to administer the vaccine in a variety of community settings. This study illustrates COVID-19 vaccine roll-out in an under-resourced urban area in Chicago and provides insight on future implementation of vaccine intervention in hard to reach communities.
MeSH term(s)	2019-nCoV Vaccine mRNA-1273 ; Adolescent ; Adult ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Vaccines ; Chicago ; Female ; Hispanic or Latino ; Humans ; Male ; Middle Aged ; Young Adult
Chemical Substances	COVID-19 Vaccines ; 2019-nCoV Vaccine mRNA-1273 (EPK39PL4R4)
Language	English
Publishing date	2022-06-20
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2022.863125
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Article ; Online: Substance Use Screening in Geriatric Primary Care: Cultural Issues and Alcohol Consumption in the Deep South.

Allen, Rebecca S / Lin, Shayne S H / Ly, Timothy K / Jacobs, M Lindsey / McKinney, Robert E / Cox, Brian S / Albright, Amy E / Dragan, Deanna M / Carroll, Dana / Halli-Tierney, Anne

Clinical gerontologist

2024 , Page(s) 1–9

Abstract: Objectives: To investigate indicators of potentially hazardous alcohol use among older adults living in a region with high substance use stigma.: Methods: Patients at a university-affiliated geriatrics clinic in the Deep South of theUS completed ... ...

Abstract	Objectives: To investigate indicators of potentially hazardous alcohol use among older adults living in a region with high substance use stigma. Methods: Patients at a university-affiliated geriatrics clinic in the Deep South of theUS completed behavioral health screenings including self-reported alcohol use, symptoms of depression or anxiety, and cognitive functioning between 2018 and 2022. Results: Participants ( Conclusion: Self-reported alcohol use is low in geriatric primary care in the Deep South, US, differs by race/ethnicity, and is predictive of cognitive impairment when alcohol use is hazardous. Issues of trust and stigma may play a role in self-report ofstigmatized behaviors. Clinical implications: Self-reported alcohol intake must be considered within the cultural context of regional stigma. Recommendations to address this are provided.
Language	English
Publishing date	2024-03-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	226146-7
ISSN	1545-2301 ; 0731-7115
ISSN (online)	1545-2301
ISSN	0731-7115
DOI	10.1080/07317115.2024.2326523
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Article ; Online: SMART use of medications for the treatment of adolescent severe obesity: A sequential multiple assignment randomized trial protocol.

Fox, Claudia K / Vock, David M / Sherwood, Nancy E / Gross, Amy C / Ryder, Justin R / Bensignor, Megan O / Bomberg, Eric M / Sunni, Muna / Bramante, Carolyn T / Jacobs, Nina / Raatz, Sarah J / Kelly, Aaron S

Contemporary clinical trials

2024 Volume 138, Page(s) 107444

Abstract: Background: Severe obesity is a complex, chronic disease affecting nearly 9% of adolescents in the U.S. Although the current mainstay of treatment is lifestyle therapy, pediatric clinical practice guidelines recommend the addition of adjunct anti- ... ...

Abstract	Background: Severe obesity is a complex, chronic disease affecting nearly 9% of adolescents in the U.S. Although the current mainstay of treatment is lifestyle therapy, pediatric clinical practice guidelines recommend the addition of adjunct anti-obesity medication (AOM), such as phentermine and topiramate. However, guidance regarding when adjunct AOM should be started and how AOM should be used is unclear. Furthermore, an inherent limitation of current treatment guidelines is their "one-size-fits-all" approach, which does not account for the heterogeneous nature of obesity and high degree of patient variability in response to all interventions. Methods: This paper describes the study design and methods of a sequential multiple assignment randomized trial (SMART), "SMART Use of Medications for the Treatment of Adolescent Severe Obesity." The trial will examine 1) when to start AOM (specifically phentermine) in adolescents who are not responding to lifestyle therapy and 2) how to modify AOM when there is a sub-optimal response to the initial pharmacological intervention (specifically, for phentermine non-responders, is it better to add topiramate to phentermine or switch to topiramate monotherapy). Critically, participant characteristics that may differentially affect response to treatment will be assessed and evaluated as potential moderators of intervention efficacy. Conclusion: Data from this study will be used to inform the development of an adaptive intervention for the treatment of adolescent severe obesity that includes empirically-derived decision rules regarding when and how to use AOM. Future research will test this adaptive intervention against standard "one-size-fits-all" treatments.
MeSH term(s)	Adolescent ; Child ; Humans ; Anti-Obesity Agents/therapeutic use ; Anti-Obesity Agents/pharmacology ; Fructose/therapeutic use ; Obesity, Morbid ; Pediatric Obesity/drug therapy ; Phentermine/therapeutic use ; Topiramate/therapeutic use ; Weight Loss ; Randomized Controlled Trials as Topic
Chemical Substances	Anti-Obesity Agents ; Fructose (30237-26-4) ; Phentermine (C045TQL4WP) ; Topiramate (0H73WJJ391)
Language	English
Publishing date	2024-01-12
Publishing country	United States
Document type	Clinical Trial Protocol ; Journal Article
ZDB-ID	2182176-8
ISSN	1559-2030 ; 1551-7144
ISSN (online)	1559-2030
ISSN	1551-7144
DOI	10.1016/j.cct.2024.107444
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Article ; Online: Fresh Embryo Transfer Cycle Characteristics and Outcomes Following In Vitro Fertilization via Intracytoplasmic Sperm Injection Among Patients With and Without COVID-19 Vaccination.

Jacobs, Emily / Summers, Karen / Sparks, Amy / Mejia, Rachel

JAMA network open

2022 Volume 5, Issue 4, Page(s) e228625

MeSH term(s)	COVID-19/prevention & control ; COVID-19 Vaccines/therapeutic use ; Embryo Transfer ; Fertilization in Vitro ; Humans ; Sperm Injections, Intracytoplasmic ; Vaccination
Chemical Substances	COVID-19 Vaccines
Language	English
Publishing date	2022-04-01
Publishing country	United States
Document type	Journal Article
ISSN	2574-3805
ISSN (online)	2574-3805
DOI	10.1001/jamanetworkopen.2022.8625
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Article ; Online: Examining the Correlation Between PrEP Use and Black:White Disparities in HIV Incidence in the Ending the HIV Epidemic Priority Jurisdictions.

Bunting, Samuel R / Hunt, Bijou / Boshara, Arianna / Jacobs, Jacquelyn / Johnson, Amy K / Hazra, Aniruddha / Glick, Nancy

Journal of general internal medicine

2022 Volume 38, Issue 2, Page(s) 382–389

Abstract: Introduction: HIV incidence remains high in the U.S. as do disparities in new HIV diagnosis between White and Black populations and access to preventive therapies like pre-exposure prophylaxis (PrEP). The federal Ending the HIV Epidemic (EHE) initiative ...

Abstract	Introduction: HIV incidence remains high in the U.S. as do disparities in new HIV diagnosis between White and Black populations and access to preventive therapies like pre-exposure prophylaxis (PrEP). The federal Ending the HIV Epidemic (EHE) initiative was developed to prioritize resources to 50 jurisdictions with high HIV incidence. Methods: We conducted secondary analyses of data (2013-2019) from the CDC, Census Bureau, and AIDSVu to evaluate the correlation between PrEP use, HIV incidence, and HIV incidence disparities. We compared the PrEP-to-need ratio (PnR) with the ratio of Black and White HIV incidence rates in 46 EHE counties. Subsequent analyses were performed for the seven states that contained multiple EHE counties. Results: These 46 counties represented 25.9% of the U.S. population in 2019. HIV incidence ranged from 10.5 in Sacramento County, CA, to 59.6 in Fulton County, GA (per 100,000). HIV incidence disparity ranged from 1.5 in Orleans Parish, LA, to 12.1 in Montgomery County, MD. PnR ranged from 26.8 in New York County, NY, to 1.46 in Shelby County, TN. Change in HIV incidence disparities and percent change in PnR were not significantly correlated (ρ = 0.06, p = 0.69). Change in overall HIV incidence was significantly correlated with increase in PnR (ρ = -0.42, p = 0.004). Conclusions: PrEP has the potential to significantly decrease HIV incidence; however, this benefit has not been conferred equally. Within EHE priority counties, we found significant HIV incidence disparities between White and Black populations. PrEP has decreased overall HIV incidence, but does not appear to have decreased HIV incidence disparity.
MeSH term(s)	Humans ; Black or African American ; HIV Infections/prevention & control ; Incidence ; Pre-Exposure Prophylaxis ; United States ; White ; Healthcare Disparities
Language	English
Publishing date	2022-06-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	639008-0
ISSN	1525-1497 ; 0884-8734
ISSN (online)	1525-1497
ISSN	0884-8734
DOI	10.1007/s11606-022-07687-y
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Article ; Online: A Community-Informed Approach to COVID-19 Vaccine Roll-Out in Under-served Areas in Chicago

Laura DiVirgilio / Arianna Boshara / Bijou R. Hunt / Jacquelyn Jacobs / Kate Just / Amy K. Johnson

Frontiers in Public Health, Vol

2022 Volume 10

Abstract	The availability of the COVID-19 vaccine in the US created an urgent need for strategies to achieve widespread vaccine distribution, but approaches to achieving equitable distribution, including reaching communities of color, varied across the country. To add to the knowledge base around targeted vaccine roll-out among underserved communities, the current study presents results from patient vaccination data and staff interviews conducted at Sinai Chicago, a safety-net healthcare system serving under-resourced communities. A total of 11,313 patients received at least one dose of Pfizer or Moderna COVID-19 vaccine between January and October 2021 at a Sinai Chicago facility. The sample was primarily comprised of Hispanic and non-Hispanic Black persons, with a mean age of 47 years, and was split evenly between female and male individuals. Compared to non-Hispanic White persons, Hispanic persons were 1.4 times more likely to have completed the full course of vaccination, while non-Hispanic Black persons were 40% less likely. People ages 18–24 were less likely to be fully vaccinated compared to all other adult age groups. Compared to privately insured persons, publicly insured persons were 40% less likely to have been fully vaccinated. The vaccine roll-out approach focused on educating the community through town halls and targeted messaging to address common myths and misconceptions about the vaccine, as well as developing the necessary infrastructure to administer the vaccine in a variety of community settings. This study illustrates COVID-19 vaccine roll-out in an under-resourced urban area in Chicago and provides insight on future implementation of vaccine intervention in hard to reach communities.
Keywords	COVID-19 ; vaccine ; vaccine distribution ; equity ; community-informed ; Public aspects of medicine ; RA1-1270
Subject code	360
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
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Article ; Online: COVID-19 health inequities and association with mechanical ventilation and prolonged length of stay at an urban safety-net health system in Chicago.

Jacobs, Jacquelyn / Johnson, Amy K / Boshara, Arianna / Hunt, Bijou / Khouri, Christina / Cruz, Javier / Glick, Nancy

PloS one

2021 Volume 16, Issue 10, Page(s) e0258243

Abstract: Millions of Americans have been infected with COVID-19 and communities of color have been disproportionately burdened. We investigated the relationship between demographic characteristics and COVID-19 positivity, and comorbidities and severe COVID-19 ... ...

Abstract	Millions of Americans have been infected with COVID-19 and communities of color have been disproportionately burdened. We investigated the relationship between demographic characteristics and COVID-19 positivity, and comorbidities and severe COVID-19 illness (use of mechanical ventilation and length of stay) within a racial/ethnic minority population. Patients tested for COVID-19 between March 2020 and January 2021 (N = 14171) were 49.9% (n = 7072) female; 50.1% (n = 7104) non-Hispanic Black; 33.2% (n = 4698) Hispanic; and 23.6% (n = 3348) aged 65+. Overall COVID-19 positivity was 16.1% (n = 2286). Compared to females, males were 1.1 times more likely to test positive (p = 0.014). Compared to non-Hispanic Whites, non-Hispanic Black and Hispanic persons were 1.4 (p = 0.003) and 2.4 (p<0.001) times more likely, respectively, to test positive. Compared to persons ages 18-24, the odds of testing positive were statistically significantly higher for every age group except 25-34, and those aged 65+ were 2.8 times more likely to test positive (p<0.001). Adjusted for race, sex, and age, COVID-positive patients with chronic obstructive pulmonary disease were 1.9 times more likely to require a ventilator compared to those without chronic obstructive pulmonary disease (p = 0.001). Length of stay was not statistically significantly associated with any of the comorbidity variables. Our findings emphasize the importance of documenting COVID-19 disparities in marginalized populations.
MeSH term(s)	Adolescent ; Adult ; Aged ; COVID-19/ethnology ; COVID-19/pathology ; COVID-19/virology ; Chicago ; Comorbidity ; Cross-Sectional Studies ; Female ; Health Status Disparities ; Humans ; Length of Stay ; Male ; Middle Aged ; Respiration, Artificial ; SARS-CoV-2/isolation & purification ; Young Adult
Language	English
Publishing date	2021-10-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0258243
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Article ; Online: Severe Neuroinvasive West Nile Virus in Association With Anti-CD20 Monotherapy for Multiple Sclerosis.

Thebault, Simon / Gandelman, Stephanie / Lane, Camryn / Kim, Erin J / Pileggi, Caitlin / Zuroff, Leah / Yamashita, Luana D / Schindler, Matthew K / Chiu, Charles / Wilson, Michael R / Berger, Joseph R / Markowitz, Clyde / Bar-Or, Amit / Fuller, Ryan / Brandstadter, Rachel / Pruitt, Amy A / Jacobs, Dina A

Neurology(R) neuroimmunology & neuroinflammation

2023 Volume 10, Issue 5

Abstract: Objectives: The objective of this study was to report on the development of neuroinvasive West Nile virus (WNV) infection in the context of anti-CD20 monotherapy for multiple sclerosis (MS).: Methods: This is a case series study.: Results: In 2021- ...

Abstract	Objectives: The objective of this study was to report on the development of neuroinvasive West Nile virus (WNV) infection in the context of anti-CD20 monotherapy for multiple sclerosis (MS). Methods: This is a case series study. Results: In 2021-2022, we observed 4 cases of neuroinvasive WNV infection in our patient population of 2009 patients with MS on ocrelizumab, compared with a total of 46 cases of neuroinvasive WNV infection reported in Pennsylvania and 40 in New Jersey. Odds were 258 times that of the general population (95% confidence interval 97-691), χ Discussion: Neuroinvasive WNV infection can develop with anti-CD20 monotherapy in the absence of additional immunosuppression. WNV serologies may be negative in the setting of anti-CD20 treatment; in the appropriate clinical context, one should consider direct detection methods such as PCR or mNGS-based testing.
MeSH term(s)	Humans ; Female ; Male ; West Nile Fever/complications ; West Nile Fever/drug therapy ; West Nile virus ; Multiple Sclerosis/drug therapy ; Multiple Sclerosis/complications ; Antibodies, Viral ; Immunoglobulin M
Chemical Substances	Antibodies, Viral ; Immunoglobulin M
Language	English
Publishing date	2023-08-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2767740-0
ISSN	2332-7812 ; 2332-7812
ISSN (online)	2332-7812
ISSN	2332-7812
DOI	10.1212/NXI.0000000000200154
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