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  1. Article: Glomus Tumors: A Systematic Review of the Sub-Saharan Africa Experience.

    Nthumba, Peter M / Oundoh, Leahcaren Naguria

    Plastic and reconstructive surgery. Global open

    2024  Volume 12, Issue 2, Page(s) e5564

    Abstract: Background: Glomus tumors are rare benign tumors that were first described in 1812 by Wood. They arise from normal glomus apparatus, usually located in the reticular dermis of the body. Although glomus tumors are universal in occurrence, the sub-Saharan ...

    Abstract Background: Glomus tumors are rare benign tumors that were first described in 1812 by Wood. They arise from normal glomus apparatus, usually located in the reticular dermis of the body. Although glomus tumors are universal in occurrence, the sub-Saharan Africa experience has not been well documented.
    Methods: The authors performed a systematic literature review of eligible studies between 1960 and August 2023, using the terms "glomus," "tumor," "glomangioma," "glomangiomyoma," and "Africa." We also performed a search of the AIC Kijabe Hospital pathology department database of about 140,000 records, covering 30 years, for the terms "glomus tumor," "glomangioma" and "glomangiomyoma."
    Results: The systematic literature search and institutional database search produced a total of 74 patients who had glomus tumors. These patients had a lag of between 3 months and 20 years from symptom development to definitive treatment.
    Conclusions: There are very few reports of glomus tumors from sub-Saharan Africa in the current literature: the authors' histopathology database of 140,000 specimens had 46 glomus tumors (0.03%), and only 28 additional patients were found in literature from sub-Saharan Africa. The low numbers of African patients may indicate racial differences in the occurrence of glomus tumors, although this may also be due to failure of clinicians to recognize glomus tumors. The prolonged lag period between symptom development and definitive treatment for glomus tumors indicates the need for diligence in the diagnosis and treatment of a simple problem that is otherwise the cause of incapacitating pain and misery.
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2851682-5
    ISSN 2169-7574 ; 2169-7574
    ISSN (online) 2169-7574
    ISSN 2169-7574
    DOI 10.1097/GOX.0000000000005564
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Barriers to the Use of Patient-Reported Outcome Measures in Low- and Middle-income Countries.

    Malapati, Sri Harshini / Edelen, Maria O / Nthumba, Peter M / Ranganathan, Kavitha / Pusic, Andrea L

    Plastic and reconstructive surgery. Global open

    2024  Volume 12, Issue 2, Page(s) e5576

    Language English
    Publishing date 2024-02-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2851682-5
    ISSN 2169-7574 ; 2169-7574
    ISSN (online) 2169-7574
    ISSN 2169-7574
    DOI 10.1097/GOX.0000000000005576
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Burns in sub-Saharan Africa: A review.

    Nthumba, Peter M

    Burns : journal of the International Society for Burn Injuries

    2016  Volume 42, Issue 2, Page(s) 258–266

    Abstract: Objective: Burns are important preventable causes of morbidity and mortality, with a disproportionate incidence in sub-Saharan Africa. The management of these injuries in sub-Saharan Africa is a challenge because of multiple other competing problems ... ...

    Abstract Objective: Burns are important preventable causes of morbidity and mortality, with a disproportionate incidence in sub-Saharan Africa. The management of these injuries in sub-Saharan Africa is a challenge because of multiple other competing problems such as infectious diseases (HIV/AIDS, tuberculosis and malaria), terrorist acts and political instability. There is little investment in preventive measures, pre-hospital, in-hospital and post-discharge care of burns, resulting in high numbers of burns, high morbidity and mortality. Lack of data that can be used in legislation and policy formulation is a major hindrance in highlighting the problem of burns in this sub-region.
    Methods: An online search of publications on burns from sub-Saharan countries was performed.
    Results: A total of 54 publications with 32,862 patients from 14 countries qualified for inclusion in the study. The average age was 15.3 years. Children aged 10 years and below represented over 80% of the burn patient population. Males constituted 55% of those who suffered burns. Scalds were the commonest cause of thermal injuries, accounting for 59% of all burns, while flame burns accounted for 33%. The burn mortality averaged 17%, or the death of one of every five burn victims.
    Conclusions: These statistics indicate the need for an urgent review of burn policies and related legislation across the sub-Saharan region to help reduce burns, and provide a safe environment for children.
    MeSH term(s) Adolescent ; Africa South of the Sahara/epidemiology ; Age Distribution ; Body Surface Area ; Burns/epidemiology ; Burns/etiology ; Burns/mortality ; Child ; Child, Preschool ; Developing Countries ; Female ; Humans ; Incidence ; Infant ; Infant, Newborn ; Male ; Sex Distribution
    Language English
    Publishing date 2016-03
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 197308-3
    ISSN 1879-1409 ; 0305-4179
    ISSN (online) 1879-1409
    ISSN 0305-4179
    DOI 10.1016/j.burns.2015.04.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Surgical Antibiotic Prophylaxis in Children Undergoing Surgery: A Systematic Review and Meta-Analysis.

    Nthumba, Peter M / Huang, Yongxu / Perdikis, Galen / Kranzer, Katharina

    Surgical infections

    2022  Volume 23, Issue 6, Page(s) 501–515

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Antibiotic Prophylaxis/methods ; Child ; Humans ; Randomized Controlled Trials as Topic ; Reoperation ; Surgical Wound ; Surgical Wound Infection/drug therapy ; Surgical Wound Infection/prevention & control
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2022-07-12
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Review ; Systematic Review
    ZDB-ID 1440120-4
    ISSN 1557-8674 ; 1096-2964
    ISSN (online) 1557-8674
    ISSN 1096-2964
    DOI 10.1089/sur.2022.131
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5617: Show issues Location:
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  5. Article: Palliative reconstructive surgery: contextualizing palliation in resource-poor settings.

    Nthumba, Peter M

    Plastic surgery international

    2014  Volume 2014, Page(s) 275215

    Abstract: Introduction. Palliative care in Kenya and the larger Sub-Saharan Africa is considered a preserve of hospices, where these exist. Surgical training does not arm the surgeon with the skills needed to deal with the care of palliative patients. Resource ... ...

    Abstract Introduction. Palliative care in Kenya and the larger Sub-Saharan Africa is considered a preserve of hospices, where these exist. Surgical training does not arm the surgeon with the skills needed to deal with the care of palliative patients. Resource constraints demand that the surgeon be multidiscipline trained so as to be able to adequately address the needs of a growing population of patients that could benefit from surgical palliation. Patients and Methods. The author describes his experience in the management of a series of 31 palliative care patients, aged 8 to 82 years. There were a total of nine known or presumed mortalities in the first year following surgery; 17 patients experienced an improved quality of life for at least 6 months after surgery. Fourteen of these were disease-free at 6 months. Conclusion. Palliative reconstructive surgery is indicated in a select number of patients. Although cure is not the primary intent of palliative surgery, the potential benefits of an improved quality of life and the possibility of cure should encourage a more proactive role for the surgeon. The need for palliative care can be expected to increase significantly in Africa, with the estimated fourfold increase of cancer patients over the next 50 years.
    Language English
    Publishing date 2014-10-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2589543-6
    ISSN 2090-147X ; 2090-1461
    ISSN (online) 2090-147X
    ISSN 2090-1461
    DOI 10.1155/2014/275215
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Successful Shoulder Disarticulation under Local Anesthesia in the COVID-19 Era.

    Mbabazi, Pitman / Mwaniki, Mercy / Wambua, Gloria / Kagua, Samuel / Kamau, Rosemary Wangari / Daggett, Justin / Nthumba, Peter M

    Plastic and reconstructive surgery. Global open

    2023  Volume 11, Issue 9, Page(s) e5266

    Abstract: The use of the wide-awake local anesthesia no tourniquet, a tumescent local anesthetic technique in recent years, emerged as a powerful tool primarily in hand surgery. It has been adopted in many low- and middle-income countries where it was applied to ... ...

    Abstract The use of the wide-awake local anesthesia no tourniquet, a tumescent local anesthetic technique in recent years, emerged as a powerful tool primarily in hand surgery. It has been adopted in many low- and middle-income countries where it was applied to an increasingly broad group of procedures. We report the case of an older patient with an arm liposarcoma for which surgery under general or regional anesthesia was deemed unsafe, but was successfully managed with a curative right shoulder disarticulation using tumescent local anesthesia.
    Language English
    Publishing date 2023-09-13
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2851682-5
    ISSN 2169-7574 ; 2169-7574
    ISSN (online) 2169-7574
    ISSN 2169-7574
    DOI 10.1097/GOX.0000000000005266
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Use of the osteomuscular dorsal scapular flap in the reconstruction of mandibular defects.

    Nthumba, Peter M

    Annals of plastic surgery

    2013  Volume 70, Issue 1, Page(s) 53–56

    Abstract: The gold standard for mandibular defect reconstruction is the fibular free flap. Nevertheless, the pedicled osteomuscular dorsal scapular flap as a reconstructive tool offers promise for mandibular defect reconstruction and could be the first choice in ... ...

    Abstract The gold standard for mandibular defect reconstruction is the fibular free flap. Nevertheless, the pedicled osteomuscular dorsal scapular flap as a reconstructive tool offers promise for mandibular defect reconstruction and could be the first choice in certain circumstances. Its use in resource-limited settings offers an excellent solution to otherwise difficult reconstructive problems of the mandible. In 8 patients, mandibular defects resulting from the excision of benign tumors (6), trauma (1), and chronic osteomyelitis (1) were reconstructed using the pedicled osteomuscular dorsal scapular flap; these defects included the central segment of the mandible. The pedicled osteomuscular dorsal scapular flap is an excellent choice for mandibular reconstruction; it may serve as the primary choice in patients with vascular pathology that precludes free tissue transfer, as well as in resource-limited environments, as a secondary choice after a failed free flap reconstruction.
    MeSH term(s) Adult ; Aged ; Female ; Humans ; Male ; Mandibular Diseases/surgery ; Mandibular Injuries/surgery ; Middle Aged ; Reconstructive Surgical Procedures/methods ; Scapula/transplantation ; Surgical Flaps ; Treatment Outcome
    Language English
    Publishing date 2013-01
    Publishing country United States
    Document type Evaluation Studies ; Journal Article
    ZDB-ID 423835-7
    ISSN 1536-3708 ; 0148-7043
    ISSN (online) 1536-3708
    ISSN 0148-7043
    DOI 10.1097/SAP.0b013e318230992e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Safety and Sustainability: Optimizing Outcomes and Changing Paradigms in Global Health Endeavors.

    Malapati, Sri Harshini / Ramly, Elie P / Riesel, Johanna / Pusic, Andrea L / Lee, Gordon K / Magee, William P / Nthumba, Peter M

    Plastic and reconstructive surgery. Global open

    2023  Volume 11, Issue 9, Page(s) e5256

    Abstract: Background: The need to address inequities in global surgical care has garnered increased attention since 2015, after the Lancet Commission on Global Surgery underscored the importance of ensuring safe, accessible, affordable, and timely surgical and ... ...

    Abstract Background: The need to address inequities in global surgical care has garnered increased attention since 2015, after the Lancet Commission on Global Surgery underscored the importance of ensuring safe, accessible, affordable, and timely surgical and anesthetic care. The vast unmet global plastic surgery needs make plastic surgery care essential in reducing the global burden of disease. In the past, many nonprofit organizations undertook humanitarian activities within low- and middle-income countries that were primarily service-provision oriented. The Lancet Commission on Global Surgery report prompted a shift in focus from direct patient care models to sustainable global surgical models. The realization that 33% of deaths worldwide were due to unmet surgical needs led to a global shift of strategy toward the development of local systems, surgical capacity, and a focus on patient safety and quality of care within international global surgery partnerships.
    Methods: In this report, the authors explore some of the primary components of sustainable international global surgical partnerships discussed in a recent panel at the American Society of Plastic Surgeons Plastic Surgery The Meeting 2022, titled "Safety and Sustainability Overseas: Optimizing Outcomes and Changing Paradigms in Global Health Endeavors." A literature review elaborating the topics discussed was performed.
    Results: This report focuses on cultural competence and humility, international collaboration, and the use of technology and innovation, all of which are needed to promote sustainability and patient safety, within global surgery efforts.
    Conclusions: The adoption of these components into international surgical collaborations will lead to greatly enhancing the development and sustainability of mutually beneficial relationships.
    Language English
    Publishing date 2023-09-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2851682-5
    ISSN 2169-7574 ; 2169-7574
    ISSN (online) 2169-7574
    ISSN 2169-7574
    DOI 10.1097/GOX.0000000000005256
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Osteosarcoma of the jaws: a review of literature and a case report on synchronous multicentric osteosarcomas.

    Nthumba, Peter M

    World journal of surgical oncology

    2012  Volume 10, Page(s) 240

    Abstract: Background: In the head and neck region, osteosarcoma is the most common primary malignant bone tumor, representing 23% of total head and neck malignancies. Osteosarcomas of the jaws are nevertheless rare lesions, representing only 2 to 10% of all ... ...

    Abstract Background: In the head and neck region, osteosarcoma is the most common primary malignant bone tumor, representing 23% of total head and neck malignancies. Osteosarcomas of the jaws are nevertheless rare lesions, representing only 2 to 10% of all osteosarcomas. This report reviews a single-center histopathology experience with craniofacial osteosarcomas, and reports the management of unusually large synchronous mandibular and maxillary osteosarcomas in a patient.
    Patients and methods: A search of the hospital pathology database for specimens with a histological diagnosis of osteosarcomas submitted between July 1992 and May 2011 was made. A chart review of a patient with large synchronous maxillary and mandibular osteosarcomas was performed, and is reported.
    Case presentation: A 21-year-old African man with large maxillary and mandibular tumors under palliative care presented with increasing difficulties with eating, speech, and breathing. Surgical debulking was performed, with histology confirming synchronous osteosarcomas of the mandible and maxilla. The patient is well after one year, with no evidence of recurrence, having undergone no further treatment.
    Conclusion: Osteosarcomas of the jaw remain enigmatic, and a number of difficulties related to their diagnosis and treatment are yet to be resolved. True synchronous multicentric osteosarcomas of the jaws are extremely rare but, like other osteosarcomas of the jaws, have a favorable outcome, and palliative resection of such lesions, though challenging, can therefore lead to an enormously improved quality of life and self-image, and may even offer the opportunity for cure.
    MeSH term(s) Adult ; Humans ; Jaw Neoplasms/diagnostic imaging ; Jaw Neoplasms/pathology ; Jaw Neoplasms/surgery ; Male ; Neoplasms, Multiple Primary/diagnostic imaging ; Neoplasms, Multiple Primary/pathology ; Neoplasms, Multiple Primary/surgery ; Osteosarcoma/diagnostic imaging ; Osteosarcoma/pathology ; Osteosarcoma/surgery ; Radiography
    Language English
    Publishing date 2012-11-12
    Publishing country England
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 2118383-1
    ISSN 1477-7819 ; 1477-7819
    ISSN (online) 1477-7819
    ISSN 1477-7819
    DOI 10.1186/1477-7819-10-240
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The supraclavicular artery flap: a versatile flap for neck and orofacial reconstruction.

    Nthumba, Peter M

    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

    2012  Volume 70, Issue 8, Page(s) 1997–2004

    Abstract: Purpose: The supraclavicular skin is thin and pliable; it closely resembles that of the neck and facial skin, making it the perfect source of tissue for neck and orofacial reconstructions. The author sought to provide a concise compilation of the use of ...

    Abstract Purpose: The supraclavicular skin is thin and pliable; it closely resembles that of the neck and facial skin, making it the perfect source of tissue for neck and orofacial reconstructions. The author sought to provide a concise compilation of the use of the supraclavicular artery flap, including surgical landmarks, modifications, uses, common complications, and anomalies, and experience with the use of the flap in a sub-Saharan African country.
    Materials and methods: A literature search was performed on the Internet and PubMed for anatomic and clinical studies/reports in the English language on the supraclavicular artery flap with a minimum of 10 subjects and sufficient data on postoperative complications.
    Results: Five anatomic studies (2 of which included clinical cases) and 12 clinical series qualified for inclusion. These articles included 146 flaps from 73 cadaveric studies and 376 supraclavicular flaps in patients (including a series of 22 flaps by the present author). The supraclavicular artery was present in 99% of anatomic dissections and was a branch of the transverse cervical artery in 91% of anatomic dissections. Safe margins for elevation of the supraclavicular artery flap were delimited anteriorly by the clavicle, posteriorly by the superior border of the trapezius, and distally by the insertion of the deltoid muscle. Common flap complications included tip and partial flap necroses. The flap was used successfully in nononcologic and oncologic reconstructions, even with concurrent neck dissection.
    Conclusions: The pedicled supraclavicular fasciocutaneous flap is emerging as a versatile reconstructive tool for the neck and orofacial regions. It is an excellent option, especially in resource-poor environments and in patients in whom free flaps may be technically difficult. Anatomic and clinical studies have shown it to be consistently reliable, with excellent color matching for the face and neck regions, and have established reliable surgical landmarks, modifications, uses, common complications, and anomalies.
    MeSH term(s) Clavicle/blood supply ; Face/surgery ; Fascia/blood supply ; Fascia/transplantation ; Humans ; Mouth/surgery ; Muscle, Skeletal/blood supply ; Neck/surgery ; Reconstructive Surgical Procedures/methods ; Skin Transplantation/pathology ; Surgical Flaps/blood supply
    Language English
    Publishing date 2012-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 392404-x
    ISSN 1531-5053 ; 0278-2391
    ISSN (online) 1531-5053
    ISSN 0278-2391
    DOI 10.1016/j.joms.2011.08.043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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