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  1. Article: [Investigation of prevalence of soil-transmitted nematode infections among Lahu Ethnic residents in Xiaojie Township, Jinghong City, Yunnan Province].

    Du, Zun-Wei / Jiang, Jin-Yong / Li, Hong-Bin / Chen, Ran / Wang, Xue-Zhong / Dao, Tian-You

    Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control

    2014  Volume 26, Issue 1, Page(s) 75–77

    Abstract: ... behaviors and habits were requested by a standardized questionnaire in 3 villages of Xiaojie Township ...

    Abstract Objective: To understand the prevalence of human intestinal parasite infections in Lahu Ethnic residents so as to provide the evidence for effective control.
    Methods: The prevalence of soil-transmitted nematode infections in local people was determined by Kato-Katz technique and individual sanitary behaviors and habits were requested by a standardized questionnaire in 3 villages of Xiaojie Township, Jinghong City, Yunnan Province. The relationship between intestinal parasite infections and behavioral characteristics was analyzed.
    Results: Of 289 subjects, 255 individuals were infected with soil-transmitted nematodes; the prevalence was 88.24%. Among the infected individuals, 210 were found infected with hookworm and the infection rate was 72.66%; 154 subjects were infected with Ascaris lumbricoides and the infection rate was 53.29%; 13 were infected with Trichuris trichura, and the infection rate was 4.50%; 16 were infected with other parasites and the infection rate was 5.54%. The percentages of people with light infection of hookworm, A. lumbricoides and T. trichura were 90.48%, 97.40% and 100%, respectively.
    Conclusions: There is high prevalence of soil-transmitted nematode infections in Lahu Ethnic residents in Jinghong City, but the infection intensity was generally low. The control and monitoring of soil-transmitted parasite infections should be strengthened in this area.
    MeSH term(s) Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; China/epidemiology ; China/ethnology ; Female ; Humans ; Infant ; Male ; Middle Aged ; Nematode Infections/epidemiology ; Nematode Infections/prevention & control ; Prevalence ; Soil/parasitology
    Chemical Substances Soil
    Language Chinese
    Publishing date 2014-02
    Publishing country China
    Document type Journal Article
    ISSN 1005-6661
    ISSN 1005-6661
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: Coordination and Cooperation in Complex Adaptive Systems: Theory and Application

    Chen, Xiaojie / Sasaki, Tatsuya / Okada, Isamu

    2019  

    Keywords Science: general issues ; Physics ; evolutionary game theory ; cooperation ; Social learning ; evolutionary dynamics
    Size 1 electronic resource (155 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021230305
    ISBN 9782889458448 ; 288945844X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Response of CRH system in brain and gill of marine medaka to seawater acidification.

    Chen, Haijin / Feng, Yaoyi / Cui, Jinghui / Wang, Xiaojie

    Fish physiology and biochemistry

    2024  

    Abstract: Corticotropin-releasing hormone (CRH) is mainly secreted by the hypothalamus to regulate stress when environmental factors change. Gills contact with water directly and may also secrete CRH to maintain local homeostasis. Ocean acidification changes water ...

    Abstract Corticotropin-releasing hormone (CRH) is mainly secreted by the hypothalamus to regulate stress when environmental factors change. Gills contact with water directly and may also secrete CRH to maintain local homeostasis. Ocean acidification changes water chemical parameters and is becoming an important environmental stressor for marine fish. The response of brain and gill CRH systems to ocean acidification remains unclear. In this study, marine medaka were exposed to CO
    Language English
    Publishing date 2024-03-21
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 292907-7
    ISSN 1573-5168 ; 0920-1742
    ISSN (online) 1573-5168
    ISSN 0920-1742
    DOI 10.1007/s10695-024-01332-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Multi-slice spatial transcriptome domain analysis with SpaDo.

    Duan, Bin / Chen, Shaoqi / Cheng, Xiaojie / Liu, Qi

    Genome biology

    2024  Volume 25, Issue 1, Page(s) 73

    Abstract: With the rapid advancements in spatial transcriptome sequencing, multiple tissue slices are now available, enabling the integration and interpretation of spatial cellular landscapes. Herein, we introduce SpaDo, a tool for multi-slice spatial domain ... ...

    Abstract With the rapid advancements in spatial transcriptome sequencing, multiple tissue slices are now available, enabling the integration and interpretation of spatial cellular landscapes. Herein, we introduce SpaDo, a tool for multi-slice spatial domain analysis, including modules for multi-slice spatial domain detection, reference-based annotation, and multiple slice clustering at both single-cell and spot resolutions. We demonstrate SpaDo's effectiveness with over 40 multi-slice spatial transcriptome datasets from 7 sequencing platforms. Our findings highlight SpaDo's potential to reveal novel biological insights in multi-slice spatial transcriptomes.
    MeSH term(s) Transcriptome ; Gene Expression Profiling ; Spatial Analysis ; Cluster Analysis ; Single-Cell Analysis
    Language English
    Publishing date 2024-03-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2040529-7
    ISSN 1474-760X ; 1474-760X
    ISSN (online) 1474-760X
    ISSN 1474-760X
    DOI 10.1186/s13059-024-03213-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Emerging solutions from the battle of defensive alliances

    Attila Szolnoki / Xiaojie Chen

    Scientific Reports, Vol 13, Iss 1, Pp 1-

    2023  Volume 9

    Abstract: Abstract Competing strategies in an evolutionary game model, or species in a biosystem, can easily form a larger unit which protects them from the invasion of an external actor. Such a defensive alliance may have two, three, four or even more members. ... ...

    Abstract Abstract Competing strategies in an evolutionary game model, or species in a biosystem, can easily form a larger unit which protects them from the invasion of an external actor. Such a defensive alliance may have two, three, four or even more members. But how effective can be such formation against an alternative group composed by other competitors? To address this question we study a minimal model where a two-member and a four-member alliances fight in a symmetric and balanced way. By presenting representative phase diagrams, we systematically explore the whole parameter range which characterizes the inner dynamics of the alliances and the intensity of their interactions. The group formed by a pair, who can exchange their neighboring positions, prevail in the majority of the parameter region. The rival quartet can only win if their inner cyclic invasion rate is significant while the mixing rate of the pair is extremely low. At specific parameter values, when neither of the alliances is strong enough, new four-member solutions emerge where a rock-paper-scissors-like trio is extended by the other member of the pair. These new solutions coexist hence all six competitors can survive. The evolutionary process is accompanied by serious finite-size effects which can be mitigated by appropriately chosen prepared initial states.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Molecular-Level Kinetic Model for Light Hydrocarbon Steam Cracking Based on the SU-BEM Framework.

    Xu, Dongyu / Zhang, Xiaojie / Chen, Zhengyu / Zhang, Linzhou

    ACS omega

    2024  Volume 9, Issue 13, Page(s) 14849–14859

    Abstract: In this work, a molecular-level kinetic model of ethane/propane steam cracking was developed by using a hybrid structural unit-bond electron matrix framework. The molecular-level simulation was conducted, creating a detailed feedstock composition, ... ...

    Abstract In this work, a molecular-level kinetic model of ethane/propane steam cracking was developed by using a hybrid structural unit-bond electron matrix framework. The molecular-level simulation was conducted, creating a detailed feedstock composition, formulating the reaction rules, and automating the generation and visualization of reaction networks. Ordinary differential equations were automatically generated based on the Arrhenius equation, while the kinetic parameters were reduced via linear free energy relations (LFERs). Furthermore, proper mathematical models for mass transfer, heat transfer, and momentum transfer within the cracking furnace were integrated into the molecular-level kinetic model, enabling the simultaneous calculation of the transfer process and chemical kinetics in steam cracking. The model was validated by its precise prediction of product yields, outlet pressure, and outlet temperature, which were collected from an industrial gas-cracking furnace.
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c07749
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Construction and Application of Safety Management Scenarios at Construction Sites

    Qiang Yang / Xiaojie Yan / Wenkai Chen / Juncheng Fan

    Applied Sciences, Vol 14, Iss 1, p

    2024  Volume 404

    Abstract: With the rapid development of the construction industry, there have been an uncountable number of damages caused by safety accidents at construction sites. Traditional safety management methods are no longer able to meet the needs of production. This ... ...

    Abstract With the rapid development of the construction industry, there have been an uncountable number of damages caused by safety accidents at construction sites. Traditional safety management methods are no longer able to meet the needs of production. This paper presents the concept of constructing safety management scenarios for construction engineering sites. Using a production base project as a research case, it analyzes the natural and human factors involved in constructing spatial–temporal scenarios at construction sites. By employing a spatial–temporal overlay method to analyze multiple safety assessment indicators, a spatial–temporal safety management scenario for the production base project is established. Subsequently, BIM and GIS technologies are applied to perform a spatial–temporal simulation of the construction site safety management scenario. This process delineates safety and hazard areas across different construction phases based on time and spatial dimensions, enabling a comprehensive safety assessment of the construction site of the production base project. The study offers a reference and guidance for improving the level of safety management at construction project sites.
    Keywords construction site safety management ; scenario construction ; space–time simulation ; safety assessment ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 690
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Preparation and Gas-Sensing Properties of Two-Dimensional Molybdenum Disulfide/One-Dimensional Copper Phthalocyanine Heterojunction.

    Chen, Guoqing / Xu, Xiaojie / Wang, Hao / Shaymurat, Talgar

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 23

    Abstract: Although 2D ... ...

    Abstract Although 2D MoS
    Language English
    Publishing date 2023-11-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23239321
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Emerging solutions from the battle of defensive alliances.

    Szolnoki, Attila / Chen, Xiaojie

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 8472

    Abstract: Competing strategies in an evolutionary game model, or species in a biosystem, can easily form a larger unit which protects them from the invasion of an external actor. Such a defensive alliance may have two, three, four or even more members. But how ... ...

    Abstract Competing strategies in an evolutionary game model, or species in a biosystem, can easily form a larger unit which protects them from the invasion of an external actor. Such a defensive alliance may have two, three, four or even more members. But how effective can be such formation against an alternative group composed by other competitors? To address this question we study a minimal model where a two-member and a four-member alliances fight in a symmetric and balanced way. By presenting representative phase diagrams, we systematically explore the whole parameter range which characterizes the inner dynamics of the alliances and the intensity of their interactions. The group formed by a pair, who can exchange their neighboring positions, prevail in the majority of the parameter region. The rival quartet can only win if their inner cyclic invasion rate is significant while the mixing rate of the pair is extremely low. At specific parameter values, when neither of the alliances is strong enough, new four-member solutions emerge where a rock-paper-scissors-like trio is extended by the other member of the pair. These new solutions coexist hence all six competitors can survive. The evolutionary process is accompanied by serious finite-size effects which can be mitigated by appropriately chosen prepared initial states.
    MeSH term(s) Biological Evolution ; Models, Biological
    Language English
    Publishing date 2023-05-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-35746-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Selection of Leptin Surrogates by a General Phenotypic Screening Method for Receptor Agonists.

    Wang, Tao / Chen, Xixi / Yang, Guang / Shi, Xiaojie

    Biomolecules

    2024  Volume 14, Issue 4

    Abstract: There is a high demand for agonist biomolecules such as cytokine surrogates in both biological and medicinal research fields. These are typically sourced through natural ligand engineering or affinity-based screening, followed by individual functional ... ...

    Abstract There is a high demand for agonist biomolecules such as cytokine surrogates in both biological and medicinal research fields. These are typically sourced through natural ligand engineering or affinity-based screening, followed by individual functional validation. However, efficient screening methods for identifying rare hits within immense libraries are very limited. In this research article, we introduce a phenotypic screening method utilizing biological receptor activation-dependent cell survival (BRADS). This method offers a high-throughput, low-background, and cost-effective approach that can be implemented in virtually any biochemical laboratory setting. As a proof-of-concept, we successfully identified a surrogate for human leptin following a two-week cell culture process, without the need for specialized high-throughput equipment or reagents. This surrogate effectively emulates the activity of native human leptin in cell validation assays. Our findings not only underscore the effectiveness of BRADS but also suggest its potential applicability to a broad range of biological receptors, including Notch and GPCRs.
    MeSH term(s) Leptin/metabolism ; Humans ; High-Throughput Screening Assays/methods ; Cell Survival/drug effects ; Phenotype ; HEK293 Cells ; Ligands ; Receptors, Leptin/agonists ; Receptors, Leptin/metabolism
    Chemical Substances Leptin ; LEP protein, human ; Ligands ; Receptors, Leptin
    Language English
    Publishing date 2024-04-09
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2701262-1
    ISSN 2218-273X ; 2218-273X
    ISSN (online) 2218-273X
    ISSN 2218-273X
    DOI 10.3390/biom14040457
    Database MEDical Literature Analysis and Retrieval System OnLINE

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