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  1. Article ; Online: Massive hemoptysis in pregnancy treated by ECMO combined with electronic bronchoscopy

    Keyu Li / Long Wen / Haibo Zhou / Zhiguo Zhou

    Heliyon, Vol 10, Iss 1, Pp e23702- (2024)

    A case report

    1481  

    Abstract: Background: Massive hemoptysis during pregnancy is very rare. Dieulafoy's disease is one of the causes of massive hemoptysis. There are few reports of ECMO use to treat massive hemoptysis during pregnancy. Findings: We report for the first time a patient ...

    Abstract Background: Massive hemoptysis during pregnancy is very rare. Dieulafoy's disease is one of the causes of massive hemoptysis. There are few reports of ECMO use to treat massive hemoptysis during pregnancy. Findings: We report for the first time a patient with Dieulafoy's disease diagnosed at 29 weeks of pregnancy. The patient's hemoptysis occurred rapidly with large volumes. The bleeding amount reached 500 ml within half an hour, with the development of asphyxia and respiratory and cardiac arrest due to a blood clot blocking the airway. After successful cardiopulmonary resuscitation, the ventilator could not maintain effective ventilation. Emergency establishment of VV-ECMO was performed to maintain oxygen, and hemostasis was successfully achieved by performing bronchial artery embolization twice. We successfully cleaned blood clots in the airway four times by freezing and using a foreign body retrieval basket with an electronic bronchoscope. At the same time, small and smooth nodular lesions were found under bronchoscopy, and blood vessels with a diameter of 1.5 mm were found under Doppler mode with an ultrasonic bronchoscope, which was consistent with a diagnosis of Dieulafoy's disease. VV-ECMO was successfully stopped on the 3rd day of the disease course, tracheal intubation was successfully removed on the 5th day of the disease course, and the patient was discharged with no complications on the 16th day of the disease course.
    Keywords Hemoptysis ; Dieulafoy disease ; VV-ECMO ; Bronchial artery embolism ; Cryotherapy ; Pregnancy ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 610
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Synthesis and application of two-dimensional organic framework materials based on metal phthalocyanine

    PU Dongdong / ZHOU Zhiguo

    Journal of Shanghai Normal University (Natural Sciences), Vol 52, Iss 1, Pp 93-

    2023  Volume 100

    Abstract: The two-dimensional(2D) organic frames of metal phthalocyanines(MPcs) have wide application value in adsorption and separation, catalysis, biochemistry and so on. The synthesis and research of 2D frames based on MPcs provide a new way to develop new ... ...

    Abstract The two-dimensional(2D) organic frames of metal phthalocyanines(MPcs) have wide application value in adsorption and separation, catalysis, biochemistry and so on. The synthesis and research of 2D frames based on MPcs provide a new way to develop new multifunctional materials with electrical, magnetic, optical, and electrochemical properties. In this paper, firstly, the structure-function relationship of metal phthalocyanine monomers for constructing 2D organic framework and the historical development and unique functions of 2D organic framework materials are introduced. Secondly, the synthesis methods of metal-phthalocyanines 2D metal-organic framework materials(MPcs-2D MOFs) and metal-phthalocyanines 2D covalent organic framework materials(MPcs-2D COFs) were introduced. Finally, their applications in sensor, catalysis, energy storage, and photodynamic therapy are summarized.
    Keywords metal phthalocyanine(mpcs) ; organic framework ; synthesis ; Science (General) ; Q1-390
    Subject code 540
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher Academic Journals Center of Shanghai Normal University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Assessing the Influence of B-US, CDFI, SE, and Patient Age on Predicting Molecular Subtypes in Breast Lesions Using Deep Learning Algorithms.

    Liu, Weiyong / Wang, Dongyue / Liu, Le / Zhou, Zhiguo

    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

    2024  

    Abstract: Objectives: Our study aims to investigate the impact of B-mode ultrasound (B-US) imaging, color Doppler flow imaging (CDFI), strain elastography (SE), and patient age on the prediction of molecular subtypes in breast lesions.: Methods: Totally 2272 ... ...

    Abstract Objectives: Our study aims to investigate the impact of B-mode ultrasound (B-US) imaging, color Doppler flow imaging (CDFI), strain elastography (SE), and patient age on the prediction of molecular subtypes in breast lesions.
    Methods: Totally 2272 multimodal ultrasound imaging was collected from 198 patients. The ResNet-18 network was employed to predict four molecular subtypes from B-US imaging, CDFI, and SE of patients with different ages. All the images were split into training and testing datasets by the ratio of 80%:20%. The predictive performance on testing dataset was evaluated through 5 metrics including mean accuracy, precision, recall, F1-scores, and confusion matrix.
    Results: Based on B-US imaging, the test mean accuracy is 74.50%, the precision is 74.84%, the recall is 72.48%, and the F1-scores is 0.73. By combining B-US imaging with CDFI, the results were increased to 85.41%, 85.03%, 85.05%, and 0.84, respectively. With the integration of B-US imaging and SE, the results were changed to 75.64%, 74.69%, 73.86%, and 0.74, respectively. Using images from patients under 40 years old, the results were 90.48%, 90.88%, 88.47%, and 0.89. When images from patients who are above 40 years old, they were changed to 81.96%, 83.12%, 80.5%, and 0.81, respectively.
    Conclusion: Multimodal ultrasound imaging can be used to accurately predict the molecular subtypes of breast lesions. In addition to B-US imaging, CDFI rather than SE contribute further to improve predictive performance. The predictive performance is notably better for patients under 40 years old compared with those who are 40 years old and above.
    Language English
    Publishing date 2024-04-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 604829-8
    ISSN 1550-9613 ; 0278-4297
    ISSN (online) 1550-9613
    ISSN 0278-4297
    DOI 10.1002/jum.16460
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: AMS-U-Net: automatic mass segmentation in digital breast tomosynthesis via U-Net.

    Qasem, Ahmad / Qin, Genggeng / Zhou, Zhiguo

    Journal of medical imaging (Bellingham, Wash.)

    2024  Volume 11, Issue 2, Page(s) 24005

    Abstract: Purpose: The objective of this study was to develop a fully automatic mass segmentation method called AMS-U-Net for digital breast tomosynthesis (DBT), a popular breast cancer screening imaging modality. The aim was to address the challenges posed by ... ...

    Abstract Purpose: The objective of this study was to develop a fully automatic mass segmentation method called AMS-U-Net for digital breast tomosynthesis (DBT), a popular breast cancer screening imaging modality. The aim was to address the challenges posed by the increasing number of slices in DBT, which leads to higher mass contouring workload and decreased treatment efficiency.
    Approach: The study used 50 slices from different DBT volumes for evaluation. The AMS-U-Net approach consisted of four stages: image pre-processing, AMS-U-Net training, image segmentation, and post-processing. The model performance was evaluated by calculating the true positive ratio (TPR), false positive ratio (FPR), F-score, intersection over union (IoU), and 95% Hausdorff distance (pixels) as they are appropriate for datasets with class imbalance.
    Results: The model achieved 0.911, 0.003, 0.911, 0.900, 5.82 for TPR, FPR, F-score, IoU, and 95% Hausdorff distance, respectively.
    Conclusions: The AMS-U-Net model demonstrated impressive visual and quantitative results, achieving high accuracy in mass segmentation without the need for human interaction. This capability has the potential to significantly increase clinical efficiency and workflow in DBT for breast cancer screening.
    Language English
    Publishing date 2024-03-23
    Publishing country United States
    Document type Journal Article
    ISSN 2329-4302
    ISSN 2329-4302
    DOI 10.1117/1.JMI.11.2.024005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The role of regulated necrosis in diabetes and its complications.

    Pang, Haipeng / Huang, Gan / Xie, Zhiguo / Zhou, Zhiguang

    Journal of molecular medicine (Berlin, Germany)

    2024  Volume 102, Issue 4, Page(s) 495–505

    Abstract: Morphologically, cell death can be divided into apoptosis and necrosis. Apoptosis, which is a type of regulated cell death, is well tolerated by the immune system and is responsible for hemostasis and cellular turnover under physiological conditions. In ... ...

    Abstract Morphologically, cell death can be divided into apoptosis and necrosis. Apoptosis, which is a type of regulated cell death, is well tolerated by the immune system and is responsible for hemostasis and cellular turnover under physiological conditions. In contrast, necrosis is defined as a form of passive cell death that leads to a dramatic inflammatory response (also referred to as necroinflammation) and causes organ dysfunction under pathological conditions. Recently, a novel form of cell death named regulated necrosis (such as necroptosis, pyroptosis, and ferroptosis) was discovered. Distinct from apoptosis, regulated necrosis is modulated by multiple internal or external factors, but meanwhile, it results in inflammation and immune response. Accumulating evidence has indicated that regulated necrosis is associated with multiple diseases, including diabetes. Diabetes is characterized by hyperglycemia caused by insulin deficiency and/or insulin resistance, and long-term high glucose leads to various diabetes-related complications. Here, we summarize the mechanisms of necroptosis, pyroptosis, and ferroptosis, and introduce recent advances in characterizing the associations between these three types of regulated necrosis and diabetes and its complications.
    MeSH term(s) Humans ; Necrosis/metabolism ; Necrosis/pathology ; Apoptosis/physiology ; Cell Death/physiology ; Pyroptosis ; Diabetes Mellitus
    Language English
    Publishing date 2024-02-23
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1223802-8
    ISSN 1432-1440 ; 0946-2716
    ISSN (online) 1432-1440
    ISSN 0946-2716
    DOI 10.1007/s00109-024-02421-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Deciphering interleukin 37's therapeutic potential: insights into alleviating inflammation in autosomal dominant polycystic kidney disease.

    Xue, Cheng / Zhou, Chenchen / Sun, Lijun / Zhang, Liming / Mao, Zhiguo

    Kidney international

    2024  Volume 105, Issue 5, Page(s) 1130

    MeSH term(s) Humans ; Polycystic Kidney, Autosomal Dominant/complications ; Polycystic Kidney, Autosomal Dominant/drug therapy ; Kidney ; Inflammation/drug therapy
    Language English
    Publishing date 2024-02-22
    Publishing country United States
    Document type Letter
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1016/j.kint.2024.01.027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Narrow-Band Green-Emitting Hybrid Organic-Inorganic Eu (II)-Iodides for Next-Generation Micro-LED Displays.

    Han, Kai / Jin, Jiance / Zhou, Xinquan / Duan, Yan / Kovalenko, Maksym V / Xia, Zhiguo

    Advanced materials (Deerfield Beach, Fla.)

    2024  , Page(s) e2313247

    Abstract: Low-dimensional metal halide perovskites are an emerging class of light-emitting materials for LED-based displays; however, their B-site cations are confined to ... ...

    Abstract Low-dimensional metal halide perovskites are an emerging class of light-emitting materials for LED-based displays; however, their B-site cations are confined to ns
    Language English
    Publishing date 2024-02-15
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1474949-X
    ISSN 1521-4095 ; 0935-9648
    ISSN (online) 1521-4095
    ISSN 0935-9648
    DOI 10.1002/adma.202313247
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Biomechanical effects of a mandibular advancement device on the periodontal ligament: Based on different bone models.

    Zhiguo, Zhang / Ruizhi, Tao / Fan, Zhou / Wenchao, Sun / Maoning, Wei

    Journal of the mechanical behavior of biomedical materials

    2023  Volume 144, Page(s) 105914

    Abstract: Obstructive sleep apnea syndrome (OSAS) is recurrent apnoea caused by upper airway obstruction during sleep. In severe cases, OSAS might lead to sudden death. Currently, the mandibular advancement device (MAD) is the preferred product for the treatment ... ...

    Abstract Obstructive sleep apnea syndrome (OSAS) is recurrent apnoea caused by upper airway obstruction during sleep. In severe cases, OSAS might lead to sudden death. Currently, the mandibular advancement device (MAD) is the preferred product for the treatment of mild to moderate OSAS because of its compliance, portability and low cost. However, many clinical studies have suggested that long-term use of MAD might cause occlusal changes, periodontitis, muscle soreness, and joint damage. In view of the difficulties in the measurement of relevant mechanical factors in vivo, the present work aimed to quantitatively analyze biomechanical mechanisms that might lead to these side effects through computer numerical simulations and a nonhomogeneous alveolar bone model was established to approximate the actual bony features of the jaw in the simulations model. First, a 3D digital model of the teeth, periodontal ligament(PDL), and alveolar bone was created on the basis of computed tomography images and assembled with a 3D model of the MAD. A nonhomogeneous alveolar bone model was created based on computed tomographic images, and the stresses acting on the PDL were computed using the finite element method. The results showed that the nonhomogeneous model could more realistically reflect the mechanical properties of the alveolar bone and obtain the true stresses compared with the homogeneous model, which underestimated the adverse effects of PDL therapy. The numerical simulations in this paper can help doctors make more accurate judgements about MAD treatment from an oral health protection perspective.
    MeSH term(s) Humans ; Periodontal Ligament/diagnostic imaging ; Occlusal Splints ; Mandibular Advancement ; Sleep Apnea, Obstructive/therapy ; Head ; Treatment Outcome
    Language English
    Publishing date 2023-05-27
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2378381-3
    ISSN 1878-0180 ; 1751-6161
    ISSN (online) 1878-0180
    ISSN 1751-6161
    DOI 10.1016/j.jmbbm.2023.105914
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Research progress in the design of gadolinium-based inorganic nanoparticles for magnetic resonance contrast agents

    ZHAO Shuo / ZHOU Zhiguo

    Journal of Shanghai Normal University (Natural Sciences), Vol 51, Iss 5, Pp 667-

    2022  Volume 675

    Abstract: Magnetic resonance imaging(MRI) is one of the common detection methods in clinical medical imaging. The most commonly used longitudinal relaxation ( T 1 ) contrast agent in clinical diagnosis is Gadopentetate Dimeglumine(Gd-DTPA). Since their ... ...

    Abstract Magnetic resonance imaging(MRI) is one of the common detection methods in clinical medical imaging. The most commonly used longitudinal relaxation ( T 1 ) contrast agent in clinical diagnosis is Gadopentetate Dimeglumine(Gd-DTPA). Since their commercialization, gadolinium-based contrast agents have been studied extensively. This paper introduces the working principle of gadolinium-based inorganic nanoparticle(Gd IONPs) contrast agents, expounds the influence of the morphology, size, surface modification, oxygen vacancy of the inorganic nanoparticles, and looks forward to the design of gadolinium-based inorganic nanoparticle contrast agents.
    Keywords gadolinium-based contrast agent ; magnetic resonance imaging(mri) ; longitudinal relaxation rate( r 1 ) ; inorganic nanoparticles ; Science (General) ; Q1-390
    Language English
    Publishing date 2022-10-01T00:00:00Z
    Publisher Academic Journals Center of Shanghai Normal University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Massive hemoptysis in pregnancy treated by ECMO combined with electronic bronchoscopy: A case report.

    Li, Keyu / Wen, Long / Zhou, Haibo / Zhou, Zhiguo

    Heliyon

    2023  Volume 10, Issue 1, Page(s) e23702

    Abstract: Background: Massive hemoptysis during pregnancy is very rare. Dieulafoy's disease is one of the causes of massive hemoptysis. There are few reports of ECMO use to treat massive hemoptysis during pregnancy.: Findings: We report for the first time a ... ...

    Abstract Background: Massive hemoptysis during pregnancy is very rare. Dieulafoy's disease is one of the causes of massive hemoptysis. There are few reports of ECMO use to treat massive hemoptysis during pregnancy.
    Findings: We report for the first time a patient with Dieulafoy's disease diagnosed at 29 weeks of pregnancy. The patient's hemoptysis occurred rapidly with large volumes. The bleeding amount reached 500 ml within half an hour, with the development of asphyxia and respiratory and cardiac arrest due to a blood clot blocking the airway. After successful cardiopulmonary resuscitation, the ventilator could not maintain effective ventilation. Emergency establishment of VV-ECMO was performed to maintain oxygen, and hemostasis was successfully achieved by performing bronchial artery embolization twice. We successfully cleaned blood clots in the airway four times by freezing and using a foreign body retrieval basket with an electronic bronchoscope. At the same time, small and smooth nodular lesions were found under bronchoscopy, and blood vessels with a diameter of 1.5 mm were found under Doppler mode with an ultrasonic bronchoscope, which was consistent with a diagnosis of Dieulafoy's disease. VV-ECMO was successfully stopped on the 3rd day of the disease course, tracheal intubation was successfully removed on the 5th day of the disease course, and the patient was discharged with no complications on the 16th day of the disease course.
    Language English
    Publishing date 2023-12-14
    Publishing country England
    Document type Case Reports
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e23702
    Database MEDical Literature Analysis and Retrieval System OnLINE

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