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  1. Article ; Online: Nodding syndrome associated with onchocerciasis.

    Colebunders, Robert / Siewe Fodjo, Joseph Nelson

    Neuroepidemiology

    2024  

    Language English
    Publishing date 2024-03-26
    Publishing country Switzerland
    Document type Letter
    ZDB-ID 603189-4
    ISSN 1423-0208 ; 0251-5350
    ISSN (online) 1423-0208
    ISSN 0251-5350
    DOI 10.1159/000538223
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Methodological challenges for conducting case-control studies to investigate the association between onchocerciasis and epilepsy including nodding syndrome.

    Colebunders, Robert / Hadermann, Amber / Siewe Fodjo, Joseph Nelson

    Brain communications

    2023  Volume 6, Issue 1, Page(s) fcad338

    Language English
    Publishing date 2023-12-20
    Publishing country England
    Document type Journal Article
    ISSN 2632-1297
    ISSN (online) 2632-1297
    DOI 10.1093/braincomms/fcad338
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The onchocerciasis hypothesis of nodding syndrome.

    Colebunders, Robert / Hadermann, Amber / Siewe Fodjo, Joseph Nelson

    PLoS neglected tropical diseases

    2023  Volume 17, Issue 8, Page(s) e0011523

    Abstract: Nodding syndrome (NS) is a phenotypic presentation of onchocerciasis-associated epilepsy (OAE). OAE is an important public health problem in areas with high ongoing Onchocerca volvulus transmission. OAE, including NS, is preventable by strengthening ... ...

    Abstract Nodding syndrome (NS) is a phenotypic presentation of onchocerciasis-associated epilepsy (OAE). OAE is an important public health problem in areas with high ongoing Onchocerca volvulus transmission. OAE, including NS, is preventable by strengthening onchocerciasis elimination programs. The presence of tau in OAE postmortem brains could be the consequence of neuroinflammation directly or indirectly induced by O. volvulus. Omics research is needed to investigate whether O. volvulus worms contain a neurotropic virus.
    MeSH term(s) Onchocerciasis/complications ; Onchocerciasis/transmission ; Nodding Syndrome/parasitology ; Onchocerca volvulus ; Humans
    Language English
    Publishing date 2023-08-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2429704-5
    ISSN 1935-2735 ; 1935-2735
    ISSN (online) 1935-2735
    ISSN 1935-2735
    DOI 10.1371/journal.pntd.0011523
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Chorioretinitis among Immigrant and Travellers. Comment on Mansour et al. Presumed Onchocerciasis Chorioretinitis Spilling over into North America, Europe and Middle East.

    Otiti-Sengeri, Juliet / Sube, Kenneth Lado Lino / Siewe Fodjo, Joseph Nelson / Otabil, Kenneth Bentum / Colebunders, Robert

    Diagnostics (Basel, Switzerland)

    2024  Volume 14, Issue 5

    Abstract: We read, with interest, the paper by Mansour et al [ ... ]. ...

    Abstract We read, with interest, the paper by Mansour et al [...].
    Language English
    Publishing date 2024-02-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics14050478
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: COVID-19 in Low and Middle Income Countries.

    Colebunders, Robert / Siewe Fodjo, Joseph Nelson

    Pathogens (Basel, Switzerland)

    2022  Volume 11, Issue 11

    Abstract: The COVID-19 pandemic is by far the worst epidemic in the last century, causing more than 6 [ ... ]. ...

    Abstract The COVID-19 pandemic is by far the worst epidemic in the last century, causing more than 6 [...].
    Language English
    Publishing date 2022-11-11
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens11111325
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Depression, anxiety and medication adherence among tuberculosis patients attending treatment centres in Fako Division, Cameroon: cross-sectional study.

    Anye, Lionel Che / Agbortabot Bissong, Marie Ebob / Njundah, Anna Longdoh / Siewe Fodjo, Joseph Nelson

    BJPsych open

    2023  Volume 9, Issue 3, Page(s) e65

    Abstract: Background: Tuberculosis remains a public health problem, particularly in developing countries. Patients with tuberculosis often suffer from anxiety and depression, which is likely to affect adherence to the long course of tuberculosis treatment.: ... ...

    Abstract Background: Tuberculosis remains a public health problem, particularly in developing countries. Patients with tuberculosis often suffer from anxiety and depression, which is likely to affect adherence to the long course of tuberculosis treatment.
    Aims: This study sought to investigate depression, anxiety and medication adherence among Cameroonian tuberculosis patients.
    Method: A cross-sectional study was conducted from March to June 2022 across five treatment centres in Fako Division, Southwest Region, Cameroon. Data were collected via face-to-face interviews with tuberculosis patients using a structured questionnaire. Sociodemographic information was obtained, and the following tools were administered to participants: the Hospital Anxiety and Depression Scale, the Oslo Social Support Scale, and the Medication Adherence Rating Scale. Multiple logistic regression models were fitted to investigate determinants of depression and anxiety.
    Results: A total of 375 participants were recruited (mean age: 35 ± 12.2 years; 60.5% male). The prevalence rates of depression and anxiety among tuberculosis patients were 47.7% and 29.9%, respectively. After adjusting for confounders, the odds of depression were significantly increased by having extrapulmonary tuberculosis, non-adherence to treatment, having no source of income, household size <5 and poor social support. Predictors for anxiety included extrapulmonary tuberculosis, defaulting tuberculosis treatment for ≥2 months, family history of mental illness, HIV/tuberculosis co-infection, being married, poor social support and non-adherence to treatment.
    Conclusions: The prevalence of depression and anxiety in tuberculosis patients is relatively high, and diverse factors may be responsible. Therefore, holistic and comprehensive care for tuberculosis patients by mental health practitioners is highly encouraged, especially for the high-risk groups identified.
    Language English
    Publishing date 2023-04-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2829557-2
    ISSN 2056-4724
    ISSN 2056-4724
    DOI 10.1192/bjo.2023.42
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Mortality among persons with epilepsy in onchocerciasis-endemic and non-endemic areas of sub-Saharan Africa: A systematic review and meta-analysis.

    Siewe Fodjo, Joseph Nelson / Van Cutsem, Gilles / Amaral, Luís-Jorge / Colebunders, Robert

    Seizure

    2023  Volume 110, Page(s) 253–261

    Abstract: Purpose: To document epilepsy-related mortality in sub-Saharan Africa (SSA) and investigate possible associations with onchocerciasis endemicity.: Methods: Systematic review with meta-analysis. Searches were performed in PubMed and Google Scholar ( ... ...

    Abstract Purpose: To document epilepsy-related mortality in sub-Saharan Africa (SSA) and investigate possible associations with onchocerciasis endemicity.
    Methods: Systematic review with meta-analysis. Searches were performed in PubMed and Google Scholar (search terms: 'epilepsy'; 'mortality/death'; 'sub-Saharan Africa'). Included studies were classified as high-risk or low-risk for onchocerciasis based on documented endemicity data. Pooled mortality rates and annual case fatality rates (CFR) were calculated, and risk factors for mortality among persons with epilepsy (PWE) were investigated using meta-regression analysis.
    Results: The 28 eligible studies reported 30 epilepsy surveys, of which 9 (30.0%) were conducted in onchocerciasis high-risk sites. The pooled epilepsy mortality rate was 20.9 (95% CI: 5.9-74.4) per 100,000 person-years, and the pooled CFR was 36.2 (95% CI: 23.9-54.4) per 1,000 PWE per year, albeit with substantial between-study heterogeneity. Compared to onchocerciasis low-risk sites, high-risk sites had higher pooled mortality (342.9 versus 10.0 per 100,000 PY; p<0.001) and CFR (57.0 versus 26.6 per 1,000 PWE per year; p = 0.001). Mortality of PWE was almost five-fold that of people without epilepsy (mortality risk ratio: 4.9; 95% CI: 3.5-6.8). Studies in onchocerciasis high-risk sites and the study which recruited only PWE with nodding syndrome were associated with higher CFR (p = 0.044 and p = 0.002, respectively). The leading causes of epilepsy-related death were status epilepticus (58.5%), drowning (15.7%), and sudden unexpected death in epilepsy (10.1%).
    Conclusion: Epilepsy mortality remains high in SSA. Most reported causes of death among PWE might be averted by improving seizure control. Better epilepsy prevention and care are urgently needed, particularly in onchocerciasis-endemic settings.
    MeSH term(s) Humans ; Onchocerciasis/epidemiology ; Onchocerciasis/complications ; Epilepsy/complications ; Seizures/complications ; Status Epilepticus/complications ; Africa South of the Sahara/epidemiology ; Prevalence
    Language English
    Publishing date 2023-07-10
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 1137610-7
    ISSN 1532-2688 ; 1059-1311
    ISSN (online) 1532-2688
    ISSN 1059-1311
    DOI 10.1016/j.seizure.2023.07.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Epilepsy prevention.

    Fodjo, Joseph Nelson Siewe / Makoy, Yibi Logora / Colebunders, Robert

    Lancet (London, England)

    2019  Volume 394, Issue 10214, Page(s) 2072

    MeSH term(s) Epilepsy ; Humans
    Language English
    Publishing date 2019-12-09
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(19)31906-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Evidence for significant COVID-19 community transmission in Somalia using a clinical case definition.

    Ahmed, Mohammed A M / Colebunders, Robert / Siewe Fodjo, Joseph Nelson

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2020  Volume 98, Page(s) 206–207

    Keywords covid19
    Language English
    Publishing date 2020-06-25
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2020.06.068
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Safety of ivermectin during pregnancy.

    Van Hees, Stijn / Raimon, Stephen / Fodjo, Joseph Nelson Siewe / Colebunders, Robert

    The Lancet. Global health

    2020  Volume 8, Issue 3, Page(s) e338

    MeSH term(s) Female ; Humans ; Ivermectin ; Pregnancy
    Chemical Substances Ivermectin (70288-86-7)
    Language English
    Publishing date 2020-02-21
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2723488-5
    ISSN 2214-109X ; 2214-109X
    ISSN (online) 2214-109X
    ISSN 2214-109X
    DOI 10.1016/S2214-109X(19)30555-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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