LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 313

Search options

  1. Article: [JSRT Honorary member-"Mr. Toshiaki Kawakami. Interview by Akiyoshi Otsuka].

    Kawakami, Toshiaki

    Nihon Hoshasen Gijutsu Gakkai zasshi

    2010  Volume 66, Issue 10, Page(s) 1311–1316

    MeSH term(s) Forecasting ; History, 20th Century ; History, 21st Century ; Japan ; Societies, Scientific/history ; Technology, Radiologic/history ; Technology, Radiologic/trends
    Language Japanese
    Publishing date 2010-10-28
    Publishing country Japan
    Document type Autobiography ; Biography ; Historical Article ; Interview
    ZDB-ID 2269092-X
    ISSN 1881-4883 ; 0369-4305
    ISSN (online) 1881-4883
    ISSN 0369-4305
    DOI 10.6009/jjrt.66.1311
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article: The many faces of IgE: an interview with Dr. Toshiaki Kawakami. Interview.

    Kawakami, Helene F

    Journal of leukocyte biology

    2008  Volume 84, Issue 2, Page(s) 368–370

    MeSH term(s) Allergy and Immunology/history ; Histamine H1 Antagonists/therapeutic use ; History, 20th Century ; History, 21st Century ; Humans ; Hypersensitivity/drug therapy ; Hypersensitivity/immunology ; Immunoglobulin E/immunology ; Immunoglobulin E/physiology ; Male ; Mast Cells/immunology ; Mast Cells/physiology
    Chemical Substances Histamine H1 Antagonists ; Immunoglobulin E (37341-29-0)
    Language English
    Publishing date 2008-08
    Publishing country United States
    Document type Biography ; Historical Article ; Interview ; Portraits
    ZDB-ID 605722-6
    ISSN 1938-3673 ; 0741-5400
    ISSN (online) 1938-3673
    ISSN 0741-5400
    DOI 10.1189/jlb.1307841
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 603: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Book ; Online: Role of TCTP in Cell Biological and Disease Processes

    Bommer, Ulrich-Axel / Kawakami, Toshiaki

    2021  

    Keywords Research & information: general ; Biology, life sciences ; Loxosceles ; brown spider ; TCTP ; venom ; toxin ; HRF ; allergy ; mast cells ; basophils ; IgE ; FcεRI ; translationally controlled tumor protein (TCTP) ; apoptosis ; conditional knockout mice ; development ; Nestin-cre ; neurogenesis ; neuronal progenitor cells ; perinatal death ; proliferation ; Mmi1 ; translationally controlled tumor protein ; autophagy ; reactive oxygen species ; rapamycin ; nitrogen starvation ; cancer ; phospho-TCTP ; DHA ; T-DM1 ; HER2-positive breast cancer ; TCTP (HRF ; fortilin) ; growth and development ; biological stress reactions ; regulation of protein synthesis ; regulated protein degradation ; cardiovascular diseases ; n/a
    Size 1 electronic resource (150 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel, Switzerland
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021289460
    ISBN 9783036522869 ; 3036522867
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: Kimishige Ishizaka 1925-2018.

    Kawakami, Toshiaki

    Nature immunology

    2018  Volume 19, Issue 9, Page(s) 900

    MeSH term(s) Allergy and Immunology/history ; History, 20th Century ; History, 21st Century ; Humans ; Hypersensitivity/immunology ; Immunoglobulin E/immunology ; Japan ; United States
    Chemical Substances Immunoglobulin E (37341-29-0)
    Language English
    Publishing date 2018-08-22
    Publishing country United States
    Document type Biography ; Historical Article ; Journal Article ; Portrait
    ZDB-ID 2016987-5
    ISSN 1529-2916 ; 1529-2908
    ISSN (online) 1529-2916
    ISSN 1529-2908
    DOI 10.1038/s41590-018-0187-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5294: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 42: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Differentiate or die!

    Kawakami, Toshiaki

    Nature immunology

    2016  Volume 17, Issue 9, Page(s) 1007–1008

    Language English
    Publishing date 2016-08-01
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2016987-5
    ISSN 1529-2916 ; 1529-2908
    ISSN (online) 1529-2916
    ISSN 1529-2908
    DOI 10.1038/ni.3531
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5294: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 42: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Editorial overview: Recent advances in research of IgE-mediated and IgE-independent allergies, an overview.

    Kawakami, Toshiaki / Blank, Ulrich

    Current opinion in immunology

    2021  Volume 72, Page(s) vi–viii

    MeSH term(s) Allergens/immunology ; Disease Susceptibility/immunology ; Humans ; Hypersensitivity/etiology ; Immunoglobulin E/immunology ; Research/trends
    Chemical Substances Allergens ; Immunoglobulin E (37341-29-0)
    Language English
    Publishing date 2021-11-05
    Publishing country England
    Document type Editorial ; Introductory Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1035767-1
    ISSN 1879-0372 ; 0952-7915
    ISSN (online) 1879-0372
    ISSN 0952-7915
    DOI 10.1016/j.coi.2021.10.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2773: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 13: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Immunoglobulin E-Dependent Activation of Immune Cells in Rhinovirus-Induced Asthma Exacerbation.

    Kawakami, Toshiaki / Kasakura, Kazumi / Kawakami, Yu / Ando, Tomoaki

    Frontiers in allergy

    2022  Volume 3, Page(s) 835748

    Abstract: Acute exacerbation is the major cause of asthma morbidity, mortality, and health-care costs. Respiratory viral infections, particularly rhinovirus (RV) infections, are associated with the majority of asthma exacerbations. The risk for bronchoconstriction ...

    Abstract Acute exacerbation is the major cause of asthma morbidity, mortality, and health-care costs. Respiratory viral infections, particularly rhinovirus (RV) infections, are associated with the majority of asthma exacerbations. The risk for bronchoconstriction with RV is associated with allergic sensitization and type 2 airway inflammation. The efficacy of the humanized anti-IgE monoclonal antibody omalizumab in treating asthma and reducing the frequency and severity of RV-induced asthma exacerbation is well-known. Despite these clinical data, mechanistic details of omalizumab's effects on RV-induced asthma exacerbation have not been well-defined for years due to the lack of appropriate animal models. In this Perspective, we discuss potential IgE-dependent roles of mast cells and dendritic cells in asthma exacerbations.
    Language English
    Publishing date 2022-02-22
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2673-6101
    ISSN (online) 2673-6101
    DOI 10.3389/falgy.2022.835748
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article ; Online: Role of TCTP in Cell Biological and Disease Processes.

    Bommer, Ulrich-Axel / Kawakami, Toshiaki

    Cells

    2021  Volume 10, Issue 9

    Abstract: Translationally controlled tumor protein (TCTP), also referred to as histamine-releasing factor (HRF) or fortilin, is a multifunctional protein, expressed in essentially all eukaryotic organisms [ ... ]. ...

    Abstract Translationally controlled tumor protein (TCTP), also referred to as histamine-releasing factor (HRF) or fortilin, is a multifunctional protein, expressed in essentially all eukaryotic organisms [...].
    MeSH term(s) Animals ; Biomarkers, Tumor/metabolism ; Humans ; Neoplasms/metabolism ; Neoplasms/pathology ; Tumor Protein, Translationally-Controlled 1
    Chemical Substances Biomarkers, Tumor ; TPT1 protein, human ; Tumor Protein, Translationally-Controlled 1
    Language English
    Publishing date 2021-09-02
    Publishing country Switzerland
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells10092290
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Histamine-Releasing Factor Is a Novel Alarmin Induced by House Dust Mite Allergen, Cytokines, and Cell Death.

    Kasakura, Kazumi / Kawakami, Yu / Jacquet, Alain / Kawakami, Toshiaki

    Journal of immunology (Baltimore, Md. : 1950)

    2022  Volume 209, Issue 10, Page(s) 1851–1859

    Abstract: Histamine-releasing factor (HRF) is a multifunctional protein with fundamental intracellular functions controlling cell survival and proliferation. HRF is also secreted during allergic reactions and promotes IgE-mediated activation of mast cells and ... ...

    Abstract Histamine-releasing factor (HRF) is a multifunctional protein with fundamental intracellular functions controlling cell survival and proliferation. HRF is also secreted during allergic reactions and promotes IgE-mediated activation of mast cells and basophils. In this study, we investigated HRF secretion and its relevance to airway inflammation. HRF monomers were constitutively secreted from BEAS-2B human bronchial epithelial cells (HBECs) and converted to oligomers over the course of culture. Stimulation with house dust mite (HDM) extract increased HRF secretion substantially. Several cytokines involved in asthma pathogenesis showed moderate effects on HRF secretion but dramatically enhanced HDM-induced HRF secretion. HDM-induced HRF secretion from BEAS-2B cells and normal HBECs proceeded via TLR2. Consistent with this, multiple TLR2 ligands, including Der p 2, Der p 5, Der p 13, and Der p 21, induced HRF secretion. Der p 10 (tropomyosin) also promoted HRF secretion. Cell death or incubation with adenosine and ATP, compounds released upon cell death, also enhanced HRF secretion. Furthermore, intranasal administration of recombinant HRF elicited robust airway inflammation in HDM-sensitized mice in an FcεRI-dependent manner. Therefore, we conclude that HRF is a novel alarmin that promotes allergic airway inflammation.
    MeSH term(s) Humans ; Animals ; Mice ; Cytokines ; Alarmins ; Histamine ; Tumor Protein, Translationally-Controlled 1 ; Toll-Like Receptor 2 ; Immunologic Factors ; Antigens, Dermatophagoides ; Cell Death ; Inflammation ; Allergens ; Pyroglyphidae ; Fibrinogen
    Chemical Substances Cytokines ; Alarmins ; Histamine (820484N8I3) ; Tumor Protein, Translationally-Controlled 1 ; Toll-Like Receptor 2 ; Immunologic Factors ; Antigens, Dermatophagoides ; Allergens ; Fibrinogen (9001-32-5)
    Language English
    Publishing date 2022-11-23
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 3056-9
    ISSN 1550-6606 ; 0022-1767 ; 1048-3233 ; 1047-7381
    ISSN (online) 1550-6606
    ISSN 0022-1767 ; 1048-3233 ; 1047-7381
    DOI 10.4049/jimmunol.2200276
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.37: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 28: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Anaphylactic or tolerant outcomes with IgE.

    Kawakami, Toshiaki / Kawakami, Yu

    The Journal of allergy and clinical immunology

    2019  Volume 145, Issue 1, Page(s) 114–115

    MeSH term(s) Allergens ; Anaphylaxis ; Humans ; Immunoglobulin E ; Receptors, IgE
    Chemical Substances Allergens ; Receptors, IgE ; Immunoglobulin E (37341-29-0)
    Language English
    Publishing date 2019-10-28
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 121011-7
    ISSN 1097-6825 ; 1085-8725 ; 0091-6749
    ISSN (online) 1097-6825 ; 1085-8725
    ISSN 0091-6749
    DOI 10.1016/j.jaci.2019.10.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.92: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top