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Article ; Online: Symptoms of anxiety and depression in women with gestational trophoblastic disease compared to women who had a miscarriage: a cross-sectional study.

Tenório, Paula Jaeger / Katz, Leila / Amorim, Melania Maria Ramos

Journal of psychosomatic obstetrics and gynaecology

2023 Volume 44, Issue 1, Page(s) 2210747

Abstract: This study was conducted between March 2020 and February 2021 to analyze anxiety and depression symptoms in 64 women with gestational trophoblastic disease (GTD) and 99 women who had miscarried. The Hospital Anxiety and Depression Scale (HADS) was ... ...

Abstract	This study was conducted between March 2020 and February 2021 to analyze anxiety and depression symptoms in 64 women with gestational trophoblastic disease (GTD) and 99 women who had miscarried. The Hospital Anxiety and Depression Scale (HADS) was applied by telephone three months after pregnancy loss. Multivariate analysis was performed using hierarchical logistic regression to evaluate associations between variables. Probable anxiety (HADS-
MeSH term(s)	Pregnancy ; Female ; Humans ; Abortion, Spontaneous/epidemiology ; Abortion, Spontaneous/psychology ; Cross-Sectional Studies ; Depression/psychology ; Anxiety/etiology ; Gestational Trophoblastic Disease/epidemiology ; Gestational Trophoblastic Disease/psychology
Language	English
Publishing date	2023-05-31
Publishing country	England
Document type	Journal Article
ZDB-ID	604816-x
ISSN	1743-8942 ; 0167-482X
ISSN (online)	1743-8942
ISSN	0167-482X
DOI	10.1080/0167482X.2023.2210747
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Article ; Online: Maternal deaths with coronavirus disease 2019: a different outcome from low- to middle-resource countries?

Amorim, Melania Maria Ramos / Soligo Takemoto, Maíra Libertad / Fonseca, Eduardo Borges da

American journal of obstetrics and gynecology

2020 Volume 223, Issue 2, Page(s) 298–299

MeSH term(s)	COVID-19 ; Coronavirus Infections/mortality ; Developing Countries ; Humans ; Maternal Mortality ; Pandemics ; Pneumonia, Viral/mortality ; Female
Keywords	covid19
Language	English
Publishing date	2020-04-26
Publishing country	United States
Document type	Letter
ZDB-ID	80016-8
ISSN	1097-6868 ; 0002-9378
ISSN (online)	1097-6868
ISSN	0002-9378
DOI	10.1016/j.ajog.2020.04.023
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Article ; Online: Sleep in children from northeastern Brazil with congenital Zika syndrome: assessment using polysomnography.

Brandão Marquis, Valéria / de Oliveira Melo, Adriana / Pradella-Hallinan, Márcia / de Vasconcelos Ataíde, Gustavo / Ramos Amorim, Melânia Maria / de Barros Miranda-Filho, Demócrito / Arraes de Alencar Ximenes, Ricardo

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

2023 Volume 19, Issue 10, Page(s) 1759–1767

Abstract: Study objectives: We performed this study to describe the characteristics of sleep in children with congenital Zika syndrome through polysomnographic assessment.: Methods: Polysomnography with neurological setup and capnography was performed. ... ...

Abstract	Study objectives: We performed this study to describe the characteristics of sleep in children with congenital Zika syndrome through polysomnographic assessment. Methods: Polysomnography with neurological setup and capnography was performed. Respiratory events were scored according to American Academy of Sleep Medicine criteria. Children were classified based on neuroclinical examination as having corticospinal plus neuromuscular abnormalities or exclusively corticospinal abnormalities. Neuroradiological classification was based on imaging exams, with children classed as having supratentorial plus infratentorial abnormalities or exclusively supratentorial abnormalities. Results: Of 65 children diagnosed with congenital Zika syndrome, sleep apnea was present in 23 children (35.4%), desaturation in 26 (40%), and snoring in 13 (20%). The most prevalent apnea type was central in 15 children (65.2%), followed by obstructive apnea in 5 (21.7%) and mixed type in 3 (13%). The average of the lowest saturation recorded was slightly below normal (89.1 ± 4.9%) and the mean partial pressure of end-tidal carbon dioxide value was normal. Periodic leg movements were present in 48 of 65 children. Lower ferritin levels were observed in 84.6% of children. Palatine and pharyngeal tonsils (adenoids) were small in most children and not associated with the presence of obstructive apnea. Ventriculomegaly and subcortical and nucleus calcification were the most frequent neuroimaging findings. Supratentorial and infratentorial anomalies were present in 26.7% (16 of 60) and exclusively supratentorial changes in 73.3% (44 of 60). In the neuroclinical classification, isolated corticospinal changes were more frequent and the mean peak in capnography was lower in this group. There was no difference regarding the presence of apnea for children in the neuroclinical and neuroradiological classification groups. Conclusions: Sleep disorders were frequent in children with congenital Zika syndrome, with central sleep apnea being the main finding. Citation: Brandão Marquis V, de Oliveira Melo A, Pradella-Hallinan M, et al. Sleep in children from northeastern Brazil with congenital Zika syndrome: assessment using polysomnography.
MeSH term(s)	Humans ; Child ; Polysomnography ; Zika Virus Infection/complications ; Zika Virus Infection/diagnosis ; Brazil ; Sleep ; Sleep Apnea Syndromes/diagnosis ; Sleep Apnea, Obstructive/complications ; Airway Obstruction/complications ; Zika Virus
Language	English
Publishing date	2023-06-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2397213-0
ISSN	1550-9397 ; 1550-9389
ISSN (online)	1550-9397
ISSN	1550-9389
DOI	10.5664/jcsm.10674
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Article: Maternal deaths with coronavirus disease 2019: a different outcome from low- to middle-resource countries?

Amorim, Melania Maria Ramos / Soligo Takemoto, Maíra Libertad / Fonseca, Eduardo Borges da

Am J Obstet Gynecol

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #378902
Database	COVID19

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Article ; Online: The Impact of COVID-19 Pandemic and Social Distancing on Motor Function and Growth of Children with Congenital Zika Syndrome: A Prospective Cohort Study.

Gama, Gabriela Lopes / Salvino, Ana Stela / Tavares, Jousilene de Sales / Gregorio, José Geraldo Ribeiro / Moreira, Karinny Michelle Alves / Amorim, Melania Maria Ramos / Melo, Adriana

Developmental neurorehabilitation

2022 Volume 26, Issue 2, Page(s) 123–129

Abstract: This article describes the impact of social distancing during the COVID-19 pandemic on the motor function and growth of children with congenital Zika syndrome (CZS). Children's motor function, weight, height and joint range of movement (ROM) were ... ...

Abstract	This article describes the impact of social distancing during the COVID-19 pandemic on the motor function and growth of children with congenital Zika syndrome (CZS). Children's motor function, weight, height and joint range of movement (ROM) were evaluated before the onset of the pandemic and soon after their return to face-to-face activities at a rehabilitation center. Fifty-two children (Mean 46.07 months, SD 3.76 months) were assessed. Results showed a reduction in proportion of children with adequate body mass index (p = .04), an increase in proportion with adequate height (p < 0.001), deterioration in gross motor function in children with severe motor impairment (p < .01), and a reduction in the maximum ROM for shoulder (p < .01) and wrist flexion (p = .046), elbow (p = .01), knee (p = .03) and ankle extension (p < .01), and an increase in hip flexion (p = .04). The social distancing period appears to have contributed to important losses in motor function and joint mobility of children with CZS; however, this period of time appeared to have less impact on their growth.
MeSH term(s)	Humans ; Child ; Zika Virus Infection/congenital ; Pandemics ; Physical Distancing ; Prospective Studies ; COVID-19 ; Zika Virus
Language	English
Publishing date	2022-12-04
Publishing country	England
Document type	Journal Article
ZDB-ID	2280007-4
ISSN	1751-8431 ; 1751-8423
ISSN (online)	1751-8431
ISSN	1751-8423
DOI	10.1080/17518423.2022.2154399
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Zs.A 5416: Show issues

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Article ; Online: Pré-natal de gestantes de risco habitual por enfermeira obstetra e obstetriz: custo-efetividade sob a perspectiva do Sistema de Saúde Suplementar.

Menezes, Mariane de Oliveira / Knobel, Roxana / Andreucci, Carla Betina / Magalhães, Claudia Garcia / Amorim, Melania Maria Ramos / Katz, Leila / Takemoto, Maíra Libertad Soligo

Cadernos de saude publica

2021 Volume 37, Issue 8, Page(s) e00076320

Abstract: In several countries, primary care for pregnant women is performed by obstetric nurses and/or midwives. In Brazil's Supplementary Health System (private health insurance and out-of-pocket care), coverage of prenatal care is mandatory and is performed by ... ...

Title translation	Prenatal care for normal-risk pregnant women by obstetric nurses and midwives: cost-effectiveness from the perspective of the Supplementary Health System in Brazil.
Abstract	In several countries, primary care for pregnant women is performed by obstetric nurses and/or midwives. In Brazil's Supplementary Health System (private health insurance and out-of-pocket care), coverage of prenatal care is mandatory and is performed by medical obstetricians. The objective of this study is to conduct a cost-effectiveness analysis, comparing clinical outcomes and costs associated with the incorporation of prenatal care by obstetric nurses and midwives in the Supplementary Health System, from the perspective of the operator of health plans as the payment source. A decision tree was built, based on data from a Cochrane Collaboration meta-analysis that showed a reduction in the risk of premature birth in the group of normal-risk pregnant women accompanied by obstetric nurses and midwives. The analysis only considered the direct medical costs covered by health plan operators for essential appointments and tests, according to the prevailing Ministry of Health protocol. The study assumed equal unit costs of consultations by medical professionals and applied an increase in the overall cost of prenatal tests associated with medical follow-up, based on data from the literature. Incremental cost-effective ratio was estimated at -BRL 10,038.43 (savings of BRL 10,038.43) per premature birth avoided. This result was consistent with the sensitivity analyses, with savings associated with the substitution ranging from -BRL 2,544.60 to -BRL 31,807.46 per premature death avoided. In conclusion, prenatal care provided by obstetric nurses and midwives was superior to that provided by medical obstetricians for the prevention of premature birth, besides resulting in cost savings.
Language	Portuguese
Publishing date	2021-08-30
Publishing country	Brazil
Document type	English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1115730-6
ISSN	1678-4464 ; 0102-311X
ISSN (online)	1678-4464
ISSN	0102-311X
DOI	10.1590/0102-311X00076320
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Zs.A 4981: Show issues

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Article ; Online: Urological outcomes in children with congenital Zika syndrome: The experience of a cohort in Campina Grande, Brazil.

Ferreira, Rayssa Vieira Brandão / Pinheiro, Hannah Cavalcante Guedes / de Oliveira Melo, Fabiana / Gama, Gabriela Lopes / Monteiro, Lucia Maria Costa / Fontes, Juliana Marin / de Oliveira Cruz, Glaura Nisya / de Araújo, Grace Ferreira / Amorim, Melania Maria Ramos / Melo, Adriana

Tropical medicine & international health : TM & IH

2022 Volume 27, Issue 6, Page(s) 583–591

Abstract: Objective: To describe the urological outcomes in children with congenital Zika syndrome (CZS) and investigate the relationship between clinical and urological findings in this population.: Methods: This cross-sectional study involved children with ... ...

Abstract	Objective: To describe the urological outcomes in children with congenital Zika syndrome (CZS) and investigate the relationship between clinical and urological findings in this population. Methods: This cross-sectional study involved children with CZS followed up by a referral centre for children with microcephaly in the state of Paraiba in northeast Brazil. The urological evaluation included clinical history, urine culture results, ultrasonography of the urinary tract, and urodynamic evaluation, following the protocol proposed by Costa Monteiro et al. (2017). Descriptive statistical analysis was performed in addition to association and correlation tests, considering clinical and urodynamic variables. Results: Among the 88 children with CZS (35.5 ± 5.5 months), 97.7% had microcephaly, and 51% presented urinary tract infection (UTI) confirmed with clinical history and lab tests. The number of confirmed UTI episodes varied from one to 14 per child. The urodynamic evaluation confirmed the presence of an overactive bladder in 78 children and incomplete voiding in 50. Urodynamic findings were associated with the number of confirmed UTI episodes, child's sex, and actual weight, in addition to the use of anticonvulsant and myorelaxant drugs. Conclusions: UTIs were confirmed in most children. Other urological outcomes observed were overactive bladder and low bladder capacity, which were associated with the number of confirmed UTI episodes, use of anticonvulsants and myorelaxants, and the child's sex and weight. These are treatable conditions, and it is paramount that paediatricians, neonatologists, and infectious disease specialists are aware of them to make clinical decisions and help reduce the risk of renal damage and other morbidities.
MeSH term(s)	Anticonvulsants ; Brazil/epidemiology ; Child ; Cross-Sectional Studies ; Humans ; Infant ; Microcephaly/epidemiology ; Urinary Bladder, Overactive/complications ; Zika Virus ; Zika Virus Infection/epidemiology
Chemical Substances	Anticonvulsants
Language	English
Publishing date	2022-05-30
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1314080-2
ISSN	1365-3156 ; 1360-2276
ISSN (online)	1365-3156
ISSN	1360-2276
DOI	10.1111/tmi.13754
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Article ; Online: Risk factors for death in patients with sepsis admitted to an obstetric intensive care unit: A cohort study.

Holanda, Ana Maria Coêlho / de Amorim, Melania Maria Ramos / Bezerra, Sammyle Maria Barros / Aschoff, Larissa Miranda Silva / Katz, Leila

Medicine

2020 Volume 99, Issue 50, Page(s) e23566

Abstract: Improving understanding of the prognostic factors associated with death resulting from sepsis in obstetric patients is essential to allow management to be optimized. This retrospective cohort study aimed to determine the risk factors for death in ... ...

Abstract	Improving understanding of the prognostic factors associated with death resulting from sepsis in obstetric patients is essential to allow management to be optimized. This retrospective cohort study aimed to determine the risk factors for death in patients with sepsis admitted to the obstetric intensive care unit of a tertiary teaching hospital in northeastern Brazil between April 2012 and April 2016.The clinical, obstetric, and laboratory data of the sepsis patients, as well as data on their final outcome, were collected. A significance level of 5% was adopted. Risk factors for death in patients with sepsis were evaluated in a multivariate analysis.During the period analyzed, 155 patients with sepsis were identified and included in the study, representing 5.2% of all obstetric intensive care unit (ICU) admissions. Of these, 14.2% (n = 22) died. The risk factors for death were septic shock at the time of hospitalization (relative risk [RR] = 3.45; 95% confidence interval [CI]: 1.64-7.25), need for vasopressors during hospitalization (RR = 17.32; 95% CI: 4.20-71.36), lactate levels >2 mmol/L at the time of diagnosis (RR = 4.60; 95% CI: 1.05-20.07), and sequential organ failure assessment score >2 at the time of diagnosis (RR = 5.97; 95% CI: 1.82-19.94). Following multiple logistic regression analysis, only the need for vasopressors during hospitalization remained as a risk factor associated with death (odds ratio [OR] = 26.38; 95% CI: 5.87-118.51).The need for vasopressors during hospitalization is associated with death in obstetric patients with sepsis.
MeSH term(s)	Adult ; Brazil/epidemiology ; Female ; Hospital Mortality ; Humans ; Intensive Care Units/statistics & numerical data ; Obstetrics and Gynecology Department, Hospital/statistics & numerical data ; Pregnancy ; Pregnancy Complications, Infectious/mortality ; Retrospective Studies ; Risk Factors ; Sepsis/mortality ; Shock, Septic/mortality ; Young Adult
Language	English
Publishing date	2020-12-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000023566
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Article ; Online: Continued Compliance and Degree of Satisfaction in Nulligravida and Parous Women with Intrauterine Contraceptive Devices.

Scavuzzi, Adriana / Souza, Alex Sandro Rolland / Amorim, Melania Maria Ramos

Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia

2016 Volume 38, Issue 3, Page(s) 132–139

Abstract: Purpose: To evaluate the compliance and degree of satisfaction of nulligravida (has not given birth) and parous (had already given birth) women who are using intrauterine devices (IUDs).: Methods: A cross-sectional cohort study was conducted ... ...

Abstract	Purpose: To evaluate the compliance and degree of satisfaction of nulligravida (has not given birth) and parous (had already given birth) women who are using intrauterine devices (IUDs). Methods: A cross-sectional cohort study was conducted comparing nulligravida and parous women who had had an IUD inserted between July 2009 and November 2011. A total of 84 nulligravida women and 73 parous women were included. Interviews were conducted with women who agreed to participate through telephone contact. Statistical analysis was performed with Student's t-test and Mann-Whitney test for numeric variables; Pearson's chi-square test to test associations; and, whenever pertinent, Fisher's exact test for categorical variables. A survival curve was constructed to estimate the likelihood of each woman continuing the use of the IUD. A significance level of 5% was established. Results: When compared with parous women, nulligravida women had a higher education level (median: 12 vs. 10 years). No statistically significant differences were found between the nulligravida and parous women with respect to information on the use of the IUD, prior use of other contraceptive methods, the reason for having chosen the IUD as the current contraceptive method, reasons for discontinuing the use and adverse effects, compliance, and degree of satisfaction. The two groups did not show any difference in terms of continued use of the IUD (p = 0.4). Conclusion: There was no difference in compliance or the degree of satisfaction or continued use of IUDs between nulligravida and parous women, suggesting that IUD use may be recommended for women who have never been pregnant.
MeSH term(s)	Adult ; Cohort Studies ; Contraception/methods ; Cross-Sectional Studies ; Female ; Humans ; Intrauterine Devices/adverse effects ; Parity ; Patient Satisfaction ; Pregnancy
Language	English
Publishing date	2016-03-29
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2105176-8
ISSN	1806-9339 ; 0100-7203
ISSN (online)	1806-9339
ISSN	0100-7203
DOI	10.1055/s-0036-1580709
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Article ; Online: Metabolic syndrome in pregnancy and postpartum: prevalence and associated factors.

Lima, Maria do Carmo Pinto / Melo, Adriana Suely Oliveira / Sena, Aline Silva Santos / Barros, Vivianne de Oliveira / Amorim, Melania Maria Ramos

Revista da Associacao Medica Brasileira (1992)

2020 Volume 65, Issue 12, Page(s) 1489–1495

Abstract: Objective: Evaluate the prevalence of metabolic syndrome (MS) and the main associated maternal factors in women without pre-gestational conditions, in early pregnancy and in the immediate postpartum.: Methods: Two hundred pregnant women were ... ...

Abstract	Objective: Evaluate the prevalence of metabolic syndrome (MS) and the main associated maternal factors in women without pre-gestational conditions, in early pregnancy and in the immediate postpartum. Methods: Two hundred pregnant women were evaluated at the 16th week of pregnancy, and 187 were reassessed postpartum. MS was diagnosed according to the criteria by the National Cholesterol Education Program Adult Treatment Panel III. In addition to the diagnostic criteria, anthropometric measures, blood pressure, metabolic profile, and visceral and subcutaneous fat thickness (by ultrasonography) were collected from the pregnant woman. The student's t-test was used to compare the prevalence of MS and its components in the 16th week and in the postpartum. Multiple logistic regression was performed to identify the principal factors associated with the syndrome. Results: The prevalence of the MS was 3.0% in early pregnancy and 9.7% postpartum (p=0.01). Following multiple logistic regression, the prepregnancy body mass index (BMI) (p=0.04) and high-density lipoprotein cholesterol (HDL-c) (p=0.02) remained associated with MS at 16 weeks, and triglyceride levels evaluated in postpartum (p<0.001) with MS in postpartum. Conclusion: The frequency of the MS was high in the immediate postpartum. The factors associated were prepregnancy BMI and HDL-c at the 16th week, as well as triglyceride levels postpartum.
MeSH term(s)	Adult ; Analysis of Variance ; Body Mass Index ; Brazil/epidemiology ; Female ; Gestational Age ; Humans ; Lipoproteins, HDL/blood ; Logistic Models ; Metabolic Syndrome/epidemiology ; Postpartum Period ; Pregnancy ; Pregnancy Complications/epidemiology ; Prevalence ; Risk Factors ; Statistics, Nonparametric ; Time Factors ; Young Adult
Chemical Substances	Lipoproteins, HDL
Language	English
Publishing date	2020-01-29
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2027973-5
ISSN	1806-9282 ; 0104-4230
ISSN (online)	1806-9282
ISSN	0104-4230
DOI	10.1590/1806-9282.65.12.1489
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