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  1. Article ; Online: Oral maxillofacial surgery resident, faculty and practitioner role models and dental students' interest in oral maxillofacial surgery careers: Does gender matter?

    Marti, Kyriaki C / Edwards, Sean P / Inglehart, Marita R

    Journal of dental education

    2023  Volume 87, Issue 7, Page(s) 1022–1032

    Abstract: ... Results: 13.8% of female and 26% of male respondents (p < 0.001) were much/very much interested in OMS ... careers. More male than female students had shadowed an OMS in an office setting (43.4% vs. 35.1%; p < 0 ... p < 0.05), were more comfortable approaching/working with OMS instructors (3.51 vs. 3.19; p < 0.01 ...

    Abstract Purpose: Residency programs in oral maxillofacial surgery (OMS) have the lowest percentage (2020: 18.4%) of female graduates among all dental specialty programs. When considering this underrepresentation of female OMS residents, prior studies have not examined how OMS role models might shape dental students' interest in OMS careers. The objectives were to assess female versus male students' OMS-related career motivation, their experiences/attitudes toward three groups of OMS role models (i.e., OMS residents, faculty, and practitioners), and relationships between role model-related experiences/attitudes and career motivation.
    Methods: 363 female and 335 male students from 14 United States and two Canadian dental schools participated in this cross-sectional study by responding to an online survey.
    Results: 13.8% of female and 26% of male respondents (p < 0.001) were much/very much interested in OMS careers. More male than female students had shadowed an OMS in an office setting (43.4% vs. 35.1%; p < 0.05). The groups did not differ in their motivation to learn more and earlier about OMS nor in the quantity of OMS-related experiences prior to and during dental school. However, male students were more satisfied with the quality of these experiences (5-point scale with 5 = most positive: Means: 3.76 vs. 3.53; p < 0.05), were more comfortable approaching/working with OMS instructors (3.51 vs. 3.19; p < 0.01) and reported to have learned more from residents (3.52 vs. 3.31; p < 0.05) and faculty (3.75 vs. 3.45; p < 0.01) than female students. Female students agreed less that OMS residents, faculty, and practitioners encouraged students to pursue OMS (3.27 vs. 3.44; p < 0.01 / 3.46 vs. 3.63; p < 0.01 / 3.45 vs. 3.61; p < 0.01). Role model-related experiences and attitudes correlated with an interest in an OMS career.
    Conclusions: The two groups do not differ in the quantity of most OMS experiences before and during dental school and their motivation to learn more and earlier about OMS. However, female students' less positive OMS-related educational experiences and less positive attitudes toward role models correlate with a lower interest in OMS careers.
    MeSH term(s) Humans ; Male ; Female ; United States ; Surgery, Oral/education ; Students, Dental ; Cross-Sectional Studies ; Faculty, Dental ; Career Choice ; Canada ; Internship and Residency ; Surveys and Questionnaires
    Language English
    Publishing date 2023-04-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 410579-5
    ISSN 1930-7837 ; 0022-0337
    ISSN (online) 1930-7837
    ISSN 0022-0337
    DOI 10.1002/jdd.13209
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Margin Analysis-Has Free Tissue Transfer Improved Oncologic Outcomes for Oral Squamous Cell Carcinoma?

    Edwards, Sean P

    Oral and maxillofacial surgery clinics of North America

    2017  Volume 29, Issue 3, Page(s) 377–381

    Abstract: Microvascular reconstruction of ablative defects has become a mainstay of contemporary management of head and neck cancer patients. These techniques offer myriad tissue options that vary in character, volume, and components and have vastly improved the ... ...

    Abstract Microvascular reconstruction of ablative defects has become a mainstay of contemporary management of head and neck cancer patients. These techniques offer myriad tissue options that vary in character, volume, and components and have vastly improved the esthetic and functional outcomes achieved in this patient population. Although consensus exists regarding the reliability and functional and esthetic benefits of free tissue transfer, the same cannot be said for oncologic outcomes. The increase in resources required for the routine use of free tissue transfer has led to asking this question-Do vascularized free flaps allow for increased surgical margins and improvements in oncologic outcomes?
    Language English
    Publishing date 2017-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1316546-x
    ISSN 1558-1365 ; 1042-3699
    ISSN (online) 1558-1365
    ISSN 1042-3699
    DOI 10.1016/j.coms.2017.05.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The obstructive sleep apnoea endotypes are similar in elderly trauma-exposed veterans with and without diagnosed PTSD.

    Brooker, Elliot J / Landry, Shane A / Mann, Dwayne / Prguda, Emina / McLeay, Sarah C / Drummond, Sean P A / Edwards, Bradley A

    Sleep medicine

    2024  Volume 115, Page(s) 48–54

    Abstract: Background: Approximately 60% of veterans living with posttraumatic stress disorder (PTSD) experience obstructive sleep apnoea (OSA). Why OSA is so prevalent in individuals with PTSD remains unknown, though PTSD may influence the underlying endotypes ... ...

    Abstract Background: Approximately 60% of veterans living with posttraumatic stress disorder (PTSD) experience obstructive sleep apnoea (OSA). Why OSA is so prevalent in individuals with PTSD remains unknown, though PTSD may influence the underlying endotypes known to cause OSA. We examined whether these endotypes (upper airway collapsibility, muscle compensation, loop gain, and the arousal threshold) differ between those with comorbid OSA and PTSD relative to their counterparts with OSA-only.
    Methods: Using the ventilatory flow pattern from diagnostic polysomnography, the OSA endotypes were measured in a retrospective cohort of 21 OSA patients with PTSD and 27 OSA-only patients. All participants were trauma exposed elderly male Australian Vietnam War veterans with mild-to-severe OSA (median Apnoea-Hypopnea index: 20.2 vs. 23.6 events/h). Age and BMI were similar between groups (70.7 vs. 71.7 years, and 28.4 vs. 28.4 kg/m
    Results: There were no significant differences in the OSA endotype traits between PTSD + OSA and OSA-only patients for upper airway collapsibility (76.68 [71.53-83.56] vs. 78.35 [72.81-83.82] %V
    Conclusion: The OSA endotypes in veterans with PTSD were similar to their trauma exposed OSA-only counterparts. PTSD appears to exert little influence on the OSA endotypes beyond the effect that age and trauma exposure may have. The aetiology of increased prevalence of OSA in PTSD remains unclear. Further work examining OSA endotypes using larger and more diverse samples is needed before robust conclusions can be made.
    MeSH term(s) Humans ; Male ; Aged ; Stress Disorders, Post-Traumatic/complications ; Stress Disorders, Post-Traumatic/epidemiology ; Retrospective Studies ; Veterans ; Australia/epidemiology ; Sleep Apnea, Obstructive/complications ; Sleep Apnea, Obstructive/epidemiology ; Sleep Apnea, Obstructive/diagnosis
    Language English
    Publishing date 2024-02-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2012041-2
    ISSN 1878-5506 ; 1389-9457
    ISSN (online) 1878-5506
    ISSN 1389-9457
    DOI 10.1016/j.sleep.2024.02.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Obstructive Sleep Apnea Is a Distinct Physiological Endotype in Individuals with Comorbid Insomnia and Sleep Apnea.

    Brooker, Elliot J / Landry, Shane A / Thomson, Luke D J / Hamilton, Garun S / Genta, Pedro R / Drummond, Sean P A / Edwards, Bradley A

    Annals of the American Thoracic Society

    2023  Volume 20, Issue 10, Page(s) 1508–1515

    Abstract: Rationale: ...

    Abstract Rationale:
    Language English
    Publishing date 2023-06-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202304-350OC
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Three-dimensional treatment planning for maxillary and mandibular segmental surgery for an adult Class III: Where old meets new.

    Conley, R Scott / Edwards, Sean P

    The Angle orthodontist

    2018  Volume 89, Issue 1, Page(s) 138–148

    Abstract: Class III open bite malocclusion can be among the most difficult case types to obtain an excellent occlusal, skeletal, and facial outcome. Treatment options include growth modification, extraction for orthodontic camouflage, and orthognathic surgery. For ...

    Abstract Class III open bite malocclusion can be among the most difficult case types to obtain an excellent occlusal, skeletal, and facial outcome. Treatment options include growth modification, extraction for orthodontic camouflage, and orthognathic surgery. For the most severely affected and non-growing patients, orthognathic surgery is often the most predictable and, in some situations, the only viable way of achieving an optimal result. The risks and benefits of surgical treatment options can occasionally be difficult to assess particularly for providers with limited experience. Two-dimensional surgical predictions can assist but do not permit the third dimension to be visualized. New techniques of computer-aided surgical simulation can enable the surgeon, orthodontist, and patient to better visualize and understand the treatment approach and enable them to make the most effective and efficient treatment related decisions. This case merges knowledge of the full spectrum of historical surgical techniques with the new approach of computer-aided surgical simulation (CASS) to perform complex segmental maxillary and mandibular surgery to obtain an excellent functional and esthetic result.
    MeSH term(s) Adult ; Cephalometry ; Esthetics, Dental ; Humans ; Malocclusion, Angle Class III/surgery ; Mandible ; Maxilla/surgery ; Orthognathic Surgical Procedures ; Treatment Outcome
    Language English
    Publishing date 2018-05-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390289-4
    ISSN 1945-7103 ; 0003-3219
    ISSN (online) 1945-7103
    ISSN 0003-3219
    DOI 10.2319/120117-823.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Development of functional organization within the sensorimotor network across the perinatal period.

    Dall'Orso, Sofia / Arichi, Tomoki / Fitzgibbon, Sean P / Edwards, A David / Burdet, Etienne / Muceli, Silvia

    Human brain mapping

    2022  Volume 43, Issue 7, Page(s) 2249–2261

    Abstract: In the mature human brain, the neural processing related to different body parts is reflected in patterns of functional connectivity, which is strongest between functional homologs in opposite cortical hemispheres. To understand how this organization is ... ...

    Abstract In the mature human brain, the neural processing related to different body parts is reflected in patterns of functional connectivity, which is strongest between functional homologs in opposite cortical hemispheres. To understand how this organization is first established, we investigated functional connectivity between limb regions in the sensorimotor cortex in 400 preterm and term infants aged across the equivalent period to the third trimester of gestation (32-45 weeks postmenstrual age). Masks were obtained from empirically derived functional responses in neonates from an independent data set. We demonstrate the early presence of a crude but spatially organized functional connectivity, that rapidly matures across the preterm period to achieve an adult-like configuration by the normal time of birth. Specifically, connectivity was strongest between homolog regions, followed by connectivity between adjacent regions (different limbs but same hemisphere) already in the preterm brain, and increased with age. These changes were specific to the sensorimotor network. Crucially, these trajectories were strongly dependent on age more than age of birth. This demonstrates that during the perinatal period the sensorimotor cortex undergoes preprogrammed changes determining the functional movement organization that are not altered by preterm birth in absence of brain injury.
    MeSH term(s) Adult ; Brain/physiology ; Brain Mapping ; Humans ; Infant ; Infant, Newborn ; Magnetic Resonance Imaging ; Neural Pathways/physiology ; Premature Birth ; Sensorimotor Cortex/diagnostic imaging
    Language English
    Publishing date 2022-01-28
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1197207-5
    ISSN 1097-0193 ; 1065-9471
    ISSN (online) 1097-0193
    ISSN 1065-9471
    DOI 10.1002/hbm.25785
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  7. Article ; Online: Orthodontic Considerations for Cleft Orthognathic Surgery.

    Yen, Stephen / Hammoudeh, Jeffrey / Edwards, Sean P / Urata, Mark

    Oral and maxillofacial surgery clinics of North America

    2020  Volume 32, Issue 2, Page(s) 249–267

    Abstract: Preparation and planning for orthognathic surgery in late adolescence depends on the complexity of unresolved problems with which the patient presents. Different strategies are presented to address these unresolved problems in the adult patient with ... ...

    Abstract Preparation and planning for orthognathic surgery in late adolescence depends on the complexity of unresolved problems with which the patient presents. Different strategies are presented to address these unresolved problems in the adult patient with cleft lip and palate. Different surgical and orthodontic treatments are presented to correct the class III malocclusion in patients with cleft lip and palate in ranges that are analogous to the envelope of discrepancy. For complex cases, the principles of achievability, stability, and esthetics should guide the decision-making process for planning the preparation for orthognathic surgery.
    MeSH term(s) Adolescent ; Adult ; Cleft Lip/surgery ; Cleft Palate/surgery ; Esthetics, Dental ; Humans ; Orthognathic Surgery ; Orthognathic Surgical Procedures
    Language English
    Publishing date 2020-03-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1316546-x
    ISSN 1558-1365 ; 1042-3699
    ISSN (online) 1558-1365
    ISSN 1042-3699
    DOI 10.1016/j.coms.2020.01.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Changes in natural head position in response to mandibular advancement.

    Lin, Xiaozhen / Edwards, Sean P

    The British journal of oral & maxillofacial surgery

    2017  Volume 55, Issue 5, Page(s) 471–475

    Abstract: We investigated the change in the natural head position and its relation to the change in the mandibular position in patients with mandibular hypoplasia. Forty-one patients treated by orthognathic surgery were divided into three groups: bilateral ... ...

    Abstract We investigated the change in the natural head position and its relation to the change in the mandibular position in patients with mandibular hypoplasia. Forty-one patients treated by orthognathic surgery were divided into three groups: bilateral sagittal split osteotomy (BSSO) advancement (n=8); BSSO advancement with genioplasty (n=12), and Le Fort I osteotomy with BSSO advancement (n=21). Cone-beam computed tomographic (CT) datasets were collected preoperatively and six weeks postoperatively. The natural head position was measured using the craniocervical angle and the distance from the second vertebra to the frontal plane, and the mandibular position was measured using the craniomandibular angle and the distance from the mandible to the frontal plane. Repeated measures two way ANOVA was used to assess the significance of differences between the angular and linear measurements, and Pearson's correlation coefficient to assess those between the change in the mandibular position and the natural head position. The craniomandibular angle increased and the mandible to frontal plane distance decreased, as planned; the craniocervical angle increased, and the distance from the second vertebra to the frontal plane decreased in all three groups. ANOVA showed a significant difference in the time factor (preoperative compared with postoperative) but no significant differences between the groups or interaction (time multiplied by group) factors. There was a significant correlation between the change in mandibular position and the change in the natural head position. Changes in the natural head position after correction of mandibular hypoplasia are correlated with the change in the mandibular position, regardless of whether a genioplasty or Le Fort I osteotomy was done.
    Language English
    Publishing date 2017-06
    Publishing country Scotland
    Document type Journal Article
    ZDB-ID 605685-4
    ISSN 1532-1940 ; 0266-4356
    ISSN (online) 1532-1940
    ISSN 0266-4356
    DOI 10.1016/j.bjoms.2017.01.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Digital Immediate Complete Denture for a Patient with Rhabdomyosarcoma: A Clinical Report.

    Mendonça, Gustavo / Edwards, Sean P / Mayers, Colin A / Meneghetti, Priscila Ceolin / Liu, Fei

    Journal of prosthodontics : official journal of the American College of Prosthodontists

    2021  Volume 30, Issue 3, Page(s) 196–201

    Abstract: Fabricating an immediate complete denture can be very challenging in some clinical situations. This clinical report describes a digital workflow to fabricate a printed maxillary immediate complete denture for a patient with a severely compromised maxilla. ...

    Abstract Fabricating an immediate complete denture can be very challenging in some clinical situations. This clinical report describes a digital workflow to fabricate a printed maxillary immediate complete denture for a patient with a severely compromised maxilla. Digital data obtained by using an intraoral scanner was utilized to reconstruct the three-dimensional (3D) image of the jaws at the desirable vertical dimension of occlusion. After performing the virtual teeth extraction and alveoloplasty, the denture base and teeth were designed. The resulting data were exported to a 3D printer for denture fabrication and the 3D printed (additively manufactured) denture was successfully inserted immediately after the surgery. After initial healing and confirmation of good retention and function, a new printed denture was fabricated by digitally duplicating the relined denture maintaining the same teeth positions but adjusting the base to a new intraoral scan of the healed ridge.
    MeSH term(s) Computer-Aided Design ; Dental Occlusion ; Denture, Complete ; Denture, Complete, Immediate ; Humans ; Maxilla/diagnostic imaging ; Maxilla/surgery ; Printing, Three-Dimensional ; Rhabdomyosarcoma
    Language English
    Publishing date 2021-01-15
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1197213-0
    ISSN 1532-849X ; 1059-941X
    ISSN (online) 1532-849X
    ISSN 1059-941X
    DOI 10.1111/jopr.13305
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Dental students' OMFS-related experiences and interest in OMFS careers: An exploration.

    Marti, Kyriaki C / Tishko, Grayson / Edwards, Sean P / Inglehart, Marita R

    Journal of dental education

    2020  Volume 85, Issue 4, Page(s) 569–581

    Abstract: ... procedure themselves (64.6% vs. 50.7%; P = 0.001), have shadowed an OMFS in an operating room (23.2% vs. 14 ... 9%; P = 0.009) prior to coming to dental school and to be much/very much interested in an OMFS ... career (36.4% vs. 12%; P < 0.001) than the students at the home school. While the majority of both groups ...

    Abstract Purpose: While the numbers of oral maxillofacial surgery (OMFS) residents increased over time, women and residents from underrepresented minority backgrounds are still underrepresented. The objectives were to assess dental students' OMFS-related personal and educational experiences and attitudes and explore which factors correlate with their interest in future OMFS careers.
    Methods: Data were collected from 493 dental students in 1 dental school and 206 students from 15 other US and Canadian dental schools.
    Results: The students in the national sample were more likely to have experienced an OMFS procedure themselves (64.6% vs. 50.7%; P = 0.001), have shadowed an OMFS in an operating room (23.2% vs. 14.9%; P = 0.009) prior to coming to dental school and to be much/very much interested in an OMFS career (36.4% vs. 12%; P < 0.001) than the students at the home school. While the majority of both groups rated their experiences with rotations in the OMFS department in the dental school (68% vs. 62.5%) and in the hospital (80.3% vs. 85.7%) as very interesting, the students in the national sample were more likely to agree/strongly agree that they were satisfied with their OMFS experiences (68.1% vs. 36.3%; P < 0.001) and had learned a lot from the OMFS faculty (57.9% vs. 30.8%) than the students in the home school. For both groups, the degree of interest in an OMFS career correlated with having had more personal OMFS experiences (home: r = 0.28; P < 0.001/other: r = 0.39; P < 0.001), more interesting OMFS experiences in the dental school (r = 0.23; P < 0.05/r = 0.40; P < 0.001) and the hospital (0.33; P < 0.05/r = 0.50; P < 0.001) and more positive attitudes toward OMFS faculty (r = 0.26; P < 0.001/r = 0.37; P < 0.001).
    Conclusions: Positive personal and educational OMFS experiences and positive attitudes toward OMFS faculty were associated with an interest in OMFS careers. These findings provide a basis for developing educational interventions aimed at increasing the percentage of women and residents from URM backgrounds in OMFS programs.
    MeSH term(s) Canada ; Career Choice ; Dental Care ; Female ; Humans ; Students, Dental ; Surgery, Oral
    Language English
    Publishing date 2020-12-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 410579-5
    ISSN 1930-7837 ; 0022-0337
    ISSN (online) 1930-7837
    ISSN 0022-0337
    DOI 10.1002/jdd.12511
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