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  1. Book ; Online: Menstrual hygiene management – a missing piece in the water agenda

    Khalid, Sidra.

    2023  

    Keywords hygiene ; livelihoods ; empowerment ; women ; policies ; infrastructure ; gender
    Language English
    Publishing date 2023-07-09T08:59:56Z
    Publisher International Water Management Institute
    Publishing country fr
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Cell membrane-coated nanoparticles

    Sidra Altaf / Khalid Ali Alkheraije

    Frontiers in Veterinary Science, Vol

    An emerging antibacterial platform for pathogens of food animals

    2023  Volume 10

    Abstract: Bacterial pathogens of animals impact food production and human health globally. Food animals act as the major host reservoirs for pathogenic bacteria and thus are highly prone to suffer from several endemic infections such as pneumonia, sepsis, mastitis, ...

    Abstract Bacterial pathogens of animals impact food production and human health globally. Food animals act as the major host reservoirs for pathogenic bacteria and thus are highly prone to suffer from several endemic infections such as pneumonia, sepsis, mastitis, and diarrhea, imposing a major health and economical loss. Moreover, the consumption of food products of infected animals is the main route by which human beings are exposed to zoonotic bacteria. Thus, there is excessive and undue administration of antibiotics to fight these virulent causative agents of food-borne illness, leading to emergence of resistant strains. Thus, highprevalence antibiotic-resistant resistant food-borne bacterial infections motivated the researchers to discover new alternative therapeutic strategies to eradicate resistant bacterial strains. One of the successful therapeutic approach for the treatment of animal infections, is the application of cell membrane-coated nanoparticles. Cell membranes of several different types of cells including platelets, red blood cells, neutrophils, cancer cells, and bacteria are being wrapped over the nanoparticles to prepare biocompatible nanoformulations. This diversity of cell membrane selection and together with the possibility of combining with an extensive range of nanoparticles, has opened a new opportunistic window for the development of more potentially effective, safe, and immune evading nanoformulations, as compared to conventionally used bare nanoparticle. This article will elaborately discuss the discovery and development of novel bioinspired cell membrane-coated nanoformulations against several pathogenic bacteria of food animals such as Klebsiella pneumoniae, Escherichia coli, Staphylococcus aureus, Salmonella enteritidis, Campylobacter jejuni, Helicobacter pylori, and Group A Streptococcus and Group B Streptococcus.
    Keywords bacteria ; nanoparticles ; cell ; infection ; animals ; antibiotic ; Veterinary medicine ; SF600-1100
    Subject code 630
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Book ; Online: Power walk activity

    Khalid, Sidra / Waqar, Kanwal

    a tool adapted for the water sector

    2023  

    Keywords gender equality ; social inclusion ; decision making ; water resources ; women
    Language English
    Publishing date 2023-12-21T10:27:24Z
    Publisher International Water Management Institute (IWMI).
    Publishing country fr
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Cell membrane-coated nanoparticles: An emerging antibacterial platform for pathogens of food animals.

    Altaf, Sidra / Alkheraije, Khalid Ali

    Frontiers in veterinary science

    2023  Volume 10, Page(s) 1148964

    Abstract: Bacterial pathogens of animals impact food production and human health globally. Food animals act as the major host reservoirs for pathogenic bacteria and thus are highly prone to suffer from several endemic infections such as pneumonia, sepsis, mastitis, ...

    Abstract Bacterial pathogens of animals impact food production and human health globally. Food animals act as the major host reservoirs for pathogenic bacteria and thus are highly prone to suffer from several endemic infections such as pneumonia, sepsis, mastitis, and diarrhea, imposing a major health and economical loss. Moreover, the consumption of food products of infected animals is the main route by which human beings are exposed to zoonotic bacteria. Thus, there is excessive and undue administration of antibiotics to fight these virulent causative agents of food-borne illness, leading to emergence of resistant strains. Thus, highprevalence antibiotic-resistant resistant food-borne bacterial infections motivated the researchers to discover new alternative therapeutic strategies to eradicate resistant bacterial strains. One of the successful therapeutic approach for the treatment of animal infections, is the application of cell membrane-coated nanoparticles. Cell membranes of several different types of cells including platelets, red blood cells, neutrophils, cancer cells, and bacteria are being wrapped over the nanoparticles to prepare biocompatible nanoformulations. This diversity of cell membrane selection and together with the possibility of combining with an extensive range of nanoparticles, has opened a new opportunistic window for the development of more potentially effective, safe, and immune evading nanoformulations, as compared to conventionally used bare nanoparticle. This article will elaborately discuss the discovery and development of novel bioinspired cell membrane-coated nanoformulations against several pathogenic bacteria of food animals such as
    Language English
    Publishing date 2023-03-06
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2834243-4
    ISSN 2297-1769
    ISSN 2297-1769
    DOI 10.3389/fvets.2023.1148964
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Online: Integrating gender equality and social inclusion for integrated water resources management

    Waqar, Kanwal / Khalid, Sidra

    a cheat sheet for practitioners.

    2023  

    Keywords gender equality ; social inclusion ; integrated water resources management ; water policies ; women ; sustainability
    Language English
    Publishing date 2023-12-22T05:06:13Z
    Publisher International Water Management Institute (IWMI)
    Publishing country fr
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: In-Silico Vaccine Design Based on a Novel Vaccine Candidate Against Infections Caused by

    Khalid, Kashaf / Irum, Sidra / Ullah, Sidra Rahmat / Andleeb, Saadia

    International journal of peptide research and therapeutics

    2021  Volume 28, Issue 1, Page(s) 16

    Abstract: Acinetobacter baumannii: Supplementary information: The online version contains supplementary material available at 10.1007/s10989-021-10316-7. ...

    Abstract Acinetobacter baumannii
    Supplementary information: The online version contains supplementary material available at 10.1007/s10989-021-10316-7.
    Language English
    Publishing date 2021-12-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2192632-3
    ISSN 1573-3904 ; 1573-3149
    ISSN (online) 1573-3904
    ISSN 1573-3149
    DOI 10.1007/s10989-021-10316-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Correlation of intra operative specimen imaging with final histopathology in breast conserving surgery for breast cancer.

    Javed, Nida / Afzal, Sidra / Parvaiz, Muhammad Asad / Rehman, Parvaiz / Khalid, Ibtissam Bin

    JPMA. The Journal of the Pakistan Medical Association

    2024  Volume 74, Issue 2, Page(s) 252–263

    Abstract: Objectives: To determine the effectiveness of specimen mammography in breast conserving surgery cases with respect to reduction in margin positivity rate, and to see whether the rate of secondary surgeries is decreased by intra-operative excision based ... ...

    Abstract Objectives: To determine the effectiveness of specimen mammography in breast conserving surgery cases with respect to reduction in margin positivity rate, and to see whether the rate of secondary surgeries is decreased by intra-operative excision based on specimen mammography evaluation.
    Methods: The retrospective study was conducted at the Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan, and comprised data from January 2018 to December 2019 related to all female breast cancer patients who underwent mastectomy or breast conserving surgery with the involvement of specimen mammography. Sensitivity, specificity, positive predictive value and negative predictive value of specimen mammography were calculated. Data was analysed using SPSS 20.
    Results: Of the 226 patients initially assessed, 65(28.7%) were excluded, and the final sample comprised 161(71.2%) women with mean age 46.71±10.47 years. The sensitivity, specificity, positive predictive value and negative predictive value of specimen mammography for the sample were 65.8%, 80.8%, 54% and 87.3%, respectively. Performing specimen mammography for intra-operative margin assessment in 12 patients was likely to spare one patient from re-excision.
    Conclusions: Intra-operative specimen mammography was found to be a reliable tool for assessing margin status.
    MeSH term(s) Female ; Humans ; Adult ; Middle Aged ; Male ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/surgery ; Breast Neoplasms/pathology ; Mastectomy, Segmental/methods ; Retrospective Studies ; Mastectomy ; Breast/pathology ; Mammography/methods
    Language English
    Publishing date 2024-02-29
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    DOI 10.47391/JPMA.8397
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A Canadian single institution real-world experience using the CROSS trial regimen in the treatment of oesophageal and gastroesophageal junction carcinoma.

    Khalid, Sidra / Hopman, Wilma M / Virik, Kiran

    Internal medicine journal

    2022  Volume 52, Issue 9, Page(s) 1587–1595

    Abstract: Background: Trimodality therapy using the ChemoRadiotherapy for Oesophageal cancer followed by Surgery Study (CROSS) trial protocol is an accepted standard of care for locally advanced oesophageal and gastroesophageal junction cancers. For medically ... ...

    Abstract Background: Trimodality therapy using the ChemoRadiotherapy for Oesophageal cancer followed by Surgery Study (CROSS) trial protocol is an accepted standard of care for locally advanced oesophageal and gastroesophageal junction cancers. For medically inoperable patients, chemoradiotherapy (CRT) has been a therapeutic option.
    Aims: This single institution review aimed to assess the real-world application of the CROSS trial protocol.
    Methods: This is a retrospective review of 83 patients who underwent CRT with carboplatin and paclitaxel with trimodality or definitive intent between June 2012 and June 2018. Sixty-five patients underwent neoadjuvant CRT (NCRT); 40 had surgery, 18 had definitive CRT (DCRT). Patients' demographics, clinical, pathological, treatment and surgical characteristics were assessed. The data were analysed in exploratory analyses and Kaplan-Meier curves.
    Results: For 83 patients, the following median values were seen: radiotherapy dose, 50.4 Gy; chemotherapy doses, 5; and time from CRT to surgery, 62 days. Twenty-three percent NCRT and 72% DCRT patients were aged ≥75 years, and 49% and 33% of these respectively had no interruptions to CRT. Patients aged ≥75 years were more likely to have DCRT (P = 0.001). Patients who underwent surgery were younger (P = 0.04). For NCRT and surgery, NCRT only and DCRT respectively, median overall survival was 35.5, 12.1 and 17.1 months (log rank P = 0.008); progression-free survival was 32.2, 10 and 9.6 months (log rank P = 0.001).
    Conclusions: Despite broadening of the CROSS trial eligibility criteria in our real-world data, there appears to be a survival benefit with trimodality therapy. The use of carboplatin and paclitaxel in DCRT may be of value and requires further study.
    MeSH term(s) Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Canada/epidemiology ; Carboplatin/therapeutic use ; Chemoradiotherapy/methods ; Clinical Trial Protocols as Topic ; Esophageal Neoplasms/drug therapy ; Esophagogastric Junction/pathology ; Humans ; Neoadjuvant Therapy/methods ; Paclitaxel/therapeutic use ; Retrospective Studies
    Chemical Substances Carboplatin (BG3F62OND5) ; Paclitaxel (P88XT4IS4D)
    Language English
    Publishing date 2022-06-18
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2045436-3
    ISSN 1445-5994 ; 1444-0903
    ISSN (online) 1445-5994
    ISSN 1444-0903
    DOI 10.1111/imj.15427
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Retraction Note: Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice.

    Afridi, Ruqayya / Khan, Ashraf Ullah / Khalid, Sidra / Shal, Bushra / Rasheed, Hina / Ullah, Muhammad Zia / Shehzad, Omer / Kim, Yeong Shik / Khan, Salman

    BMC pharmacology & toxicology

    2023  Volume 24, Issue 1, Page(s) 39

    Language English
    Publishing date 2023-06-30
    Publishing country England
    Document type Retraction of Publication
    ZDB-ID 2680259-4
    ISSN 2050-6511 ; 2050-6511
    ISSN (online) 2050-6511
    ISSN 2050-6511
    DOI 10.1186/s40360-023-00679-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Systematic review of clinical manifestations, management and outcome following accidental ingestion of liquid mosquito repellent vaporiser in children.

    Naeem, Babar / Saleem, Junaid / Haider Naqvi, Agha Syed Ali / Kausar, Sidra / Arshad, Aqdas / Kumar, Kantash / Khalid, Aashar / Kumar, Parkash

    BMJ paediatrics open

    2024  Volume 8, Issue 1

    Abstract: Background: Pyrethroid-based mosquito repellents are widely used to control mosquito-borne diseases. Liquid mosquito-repellent vaporisers are effective modes of pyrethroid delivery but can also pose significant health risks if ingested or used ... ...

    Abstract Background: Pyrethroid-based mosquito repellents are widely used to control mosquito-borne diseases. Liquid mosquito-repellent vaporisers are effective modes of pyrethroid delivery but can also pose significant health risks if ingested or used improperly.
    Objective: This systematic review was performed to assess the demographic distribution, clinical presentation, management strategies and outcomes in children resulting from accidental ingestion of liquid mosquito repellent vaporiser.
    Methods: The study adheres to the reporting standards outlined in the PRISMA Statement for Systematic Reviews and was prospectively registered with PROSPERO (record # CRD42023413937) to enhance transparency and minimise reporting bias. A comprehensive search was conducted on PubMed, Scopus and Google Scholar using specific MeSH terms related to insecticides, mosquito repellents, pyrethroids, ingestion, poisoning, toxicity and prevention. The reference lists of the included studies were also reviewed for additional relevant articles. The inclusion criteria involved studies published in peer-reviewed journals between 2000 and 2023 that focused on children under 18 years old with a history of mosquito-repellent ingestion based on primary data.
    Results: Twelve studies met the inclusion criteria; these were primarily case reports from India, China and the UAE. Male children were predominantly affected, and symptoms included vomiting, convulsions, cough and respiratory distress. Management primarily involved supportive and symptomatic measures, including atropine for salivation and antiepileptic drugs for seizures. Respiratory support was provided for respiratory complications.
    Conclusion: Despite the known risks and diverse presentations of pyrethroid poisoning caused by liquid mosquito repellent vaporiser in children, the limited substantial evidence in the literature underscores the urgent need for comprehensive research to refine management approaches and enhance preventive measures.
    MeSH term(s) Child ; Animals ; Humans ; Male ; Adolescent ; Insect Repellents ; Insecticides ; Pyrethrins ; Nebulizers and Vaporizers ; Eating
    Chemical Substances Insect Repellents ; Insecticides ; Pyrethrins
    Language English
    Publishing date 2024-03-30
    Publishing country England
    Document type Systematic Review ; Journal Article
    ISSN 2399-9772
    ISSN (online) 2399-9772
    DOI 10.1136/bmjpo-2023-002476
    Database MEDical Literature Analysis and Retrieval System OnLINE

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