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  1. Article ; Online: On 'Oxygen free radicals and iron in relation to biology and medicine: Some problems and concepts' by Barry Halliwell and John M.C.Gutteridge.

    Halliwell, Barry

    Archives of biochemistry and biophysics

    2022  Volume 726, Page(s) 109320

    Abstract: This commentary describes a highly-cited paper by John Gutteridge and myself that appeared in Arch. Biochem. Biophys. It is dedicated to the memory of John Gutteridge, my frequent co-author and a lifelong friend, who sadly passed away on July 5, 2021. ...

    Abstract This commentary describes a highly-cited paper by John Gutteridge and myself that appeared in Arch. Biochem. Biophys. It is dedicated to the memory of John Gutteridge, my frequent co-author and a lifelong friend, who sadly passed away on July 5, 2021.
    MeSH term(s) Biology ; Free Radicals ; Iron
    Chemical Substances Free Radicals ; Iron (E1UOL152H7)
    Language English
    Publishing date 2022-06-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 523-x
    ISSN 1096-0384 ; 0003-9861
    ISSN (online) 1096-0384
    ISSN 0003-9861
    DOI 10.1016/j.abb.2022.109320
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  2. Article ; Online: An interview with Barry Halliwell.

    Halliwell, Barry

    Trends in pharmacological sciences

    2013  Volume 34, Issue 6, Page(s) 301–302

    MeSH term(s) Antioxidants ; Biochemistry/history ; England ; Free Radicals ; History, 20th Century ; History, 21st Century
    Chemical Substances Antioxidants ; Free Radicals
    Language English
    Publishing date 2013-06
    Publishing country England
    Document type Autobiography ; Biography ; Historical Article ; Interview ; Portraits
    ZDB-ID 282846-7
    ISSN 1873-3735 ; 0165-6147
    ISSN (online) 1873-3735
    ISSN 0165-6147
    DOI 10.1016/j.tips.2013.04.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: On 'Oxygen free radicals and iron in relation to biology and medicine: Some problems and concepts' by Barry Halliwell and John M.C.Gutteridge

    Halliwell, Barry

    Archives of biochemistry and biophysics. 2022,

    2022  

    Abstract: This commentary describes a highly-cited paper by John Gutteridge and myself that appeared in Arch. Biochem. Biophys. It is dedicated to the memory of John Gutteridge, my frequent co-author and a lifelong friend, who sadly passed away on July 5, 2021. ...

    Abstract This commentary describes a highly-cited paper by John Gutteridge and myself that appeared in Arch. Biochem. Biophys. It is dedicated to the memory of John Gutteridge, my frequent co-author and a lifelong friend, who sadly passed away on July 5, 2021.
    Keywords biochemistry ; biophysics ; iron ; medicine ; oxygen
    Language English
    Publishing place Elsevier Inc.
    Document type Article
    Note Pre-press version
    ZDB-ID 523-x
    ISSN 1096-0384 ; 0003-9861
    ISSN (online) 1096-0384
    ISSN 0003-9861
    DOI 10.1016/j.abb.2022.109320
    Database NAL-Catalogue (AGRICOLA)

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  4. Article: Spotlight on... Barry Halliwell. Interview by Daniela Ruffell.

    Halliwell, Barry

    FEBS letters

    2007  Volume 581, Issue 26, Page(s) 5017–5018

    MeSH term(s) Aging/metabolism ; Antioxidants/metabolism ; Free Radicals/metabolism ; Humans ; Neurodegenerative Diseases/etiology
    Chemical Substances Antioxidants ; Free Radicals
    Language English
    Publishing date 2007-10-30
    Publishing country England
    Document type Interview
    ZDB-ID 212746-5
    ISSN 1873-3468 ; 0014-5793
    ISSN (online) 1873-3468
    ISSN 0014-5793
    DOI 10.1016/j.febslet.2007.09.040
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  5. Article ; Online: Understanding mechanisms of antioxidant action in health and disease.

    Halliwell, Barry

    Nature reviews. Molecular cell biology

    2023  Volume 25, Issue 1, Page(s) 13–33

    Abstract: Several different reactive oxygen species (ROS) are generated in vivo. They have roles in the development of certain human diseases whilst also performing physiological functions. ROS are counterbalanced by an antioxidant defence network, which functions ...

    Abstract Several different reactive oxygen species (ROS) are generated in vivo. They have roles in the development of certain human diseases whilst also performing physiological functions. ROS are counterbalanced by an antioxidant defence network, which functions to modulate ROS levels to allow their physiological roles whilst minimizing the oxidative damage they cause that can contribute to disease development. This Review describes the mechanisms of action of antioxidants synthesized in vivo, antioxidants derived from the human diet and synthetic antioxidants developed as therapeutic agents, with a focus on the gaps in our current knowledge and the approaches needed to close them. The Review also explores the reasons behind the successes and failures of antioxidants in treating or preventing human disease. Antioxidants may have special roles in the gastrointestinal tract, and many lifestyle features known to promote health (especially diet, exercise and the control of blood glucose and cholesterol levels) may be acting, at least in part, by antioxidant mechanisms. Certain reactive sulfur species may be important antioxidants but more accurate determinations of their concentrations in vivo are needed to help assess their contributions.
    MeSH term(s) Humans ; Antioxidants/pharmacology ; Antioxidants/metabolism ; Reactive Oxygen Species ; Health Promotion ; Oxidative Stress
    Chemical Substances Antioxidants ; Reactive Oxygen Species
    Language English
    Publishing date 2023-09-15
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2031313-5
    ISSN 1471-0080 ; 1471-0072
    ISSN (online) 1471-0080
    ISSN 1471-0072
    DOI 10.1038/s41580-023-00645-4
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  6. Book: Free radicals in biology and medicine

    Halliwell, Barry / Gutteridge, John M.

    2015  

    Author's details Barry Halliwell and John M. C. Gutteridge
    Keywords Biochemie ; Freies Radikal ; Antioxidans ; Hyperoxide ; Biologisches System
    Subject Oxidationsinhibitor ; Antioxygen ; Superoxide ; Biologische Chemie
    Language English
    Size XXXVIII, 905 S. : Ill., graph. Darst.
    Edition 5. ed.
    Publisher Oxford Univ. Press
    Publishing place Oxford u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT018740284
    ISBN 978-0-19-871748-5 ; 978-0-19-871747-8 ; 0-19-871748-2 ; 0-19-871747-4
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2015 A 3132 available for loan (reading room) Lesesaal EG

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  7. Article ; Online: Reflections of an Aging Free Radical Part 2: Meeting Inspirational People.

    Halliwell, Barry

    Antioxidants & redox signaling

    2022  Volume 38, Issue 10-12, Page(s) 792–802

    Abstract: Significance: ...

    Abstract Significance:
    MeSH term(s) Humans ; Antioxidants/metabolism ; Free Radicals ; Oxidation-Reduction ; Aging ; Signal Transduction
    Chemical Substances Antioxidants ; Free Radicals
    Language English
    Publishing date 2022-09-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1483836-9
    ISSN 1557-7716 ; 1523-0864
    ISSN (online) 1557-7716
    ISSN 1523-0864
    DOI 10.1089/ars.2022.0070
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  8. Article ; Online: Commentary for "Oxygen free radicals and iron in relation to biology and medicine: Some problems and concepts".

    Halliwell, Barry

    Archives of biochemistry and biophysics

    2022  Volume 718, Page(s) 109151

    Abstract: This commentary describes a highly-cited paper by John Gutteridge and myself that appeared in Arch. Biochem. Biophys. It is dedicated to the memory of John Gutteridge, my frequent co-author and a lifelong friend, who sadly passed away on July 5, 2021. ...

    Abstract This commentary describes a highly-cited paper by John Gutteridge and myself that appeared in Arch. Biochem. Biophys. It is dedicated to the memory of John Gutteridge, my frequent co-author and a lifelong friend, who sadly passed away on July 5, 2021.
    MeSH term(s) Biology ; Free Radicals ; Iron ; Oxygen
    Chemical Substances Free Radicals ; Iron (E1UOL152H7) ; Oxygen (S88TT14065)
    Language English
    Publishing date 2022-02-15
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 523-x
    ISSN 1096-0384 ; 0003-9861
    ISSN (online) 1096-0384
    ISSN 0003-9861
    DOI 10.1016/j.abb.2022.109151
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  9. Article ; Online: Reactive oxygen species (ROS), oxygen radicals and antioxidants: Where are we now, where is the field going and where should we go?

    Halliwell, Barry

    Biochemical and biophysical research communications

    2022  Volume 633, Page(s) 17–19

    Abstract: The field of oxygen free radicals, antioxidants and reactive oxygen species (ROS) has exploded in the past few decades, and BBRC has published several seminal papers. ROS can cause oxidative damage, but also play fundamental roles in living organisms, in ...

    Abstract The field of oxygen free radicals, antioxidants and reactive oxygen species (ROS) has exploded in the past few decades, and BBRC has published several seminal papers. ROS can cause oxidative damage, but also play fundamental roles in living organisms, in such processes as signal transduction and defence against pathogens. ROS underpin every aspect of human biology. Indeed, an endless stream of published papers refers to the biological roles of "ROS". Sadly, much of this work is mechanistically meaningless. To make progress, the detailed molecular mechanisms of action of ROS must be elucidated and appropriate methodology must be used to measure them and the oxidative damage that they can cause, as emphasized in a recent review by Murphy et al. Attention must also switch from clinical studies involving administration of high-dose supplements of vitamins E, C and β-carotene for the treatment or prevention of human disease into other promising diet-derived cytoprotective agents. One of them may be ergothioneine.
    MeSH term(s) Humans ; Reactive Oxygen Species ; Antioxidants/metabolism ; Oxidative Stress ; Free Radicals ; Vitamin E
    Chemical Substances Reactive Oxygen Species ; Antioxidants ; Free Radicals ; Vitamin E (1406-18-4)
    Language English
    Publishing date 2022-09-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 205723-2
    ISSN 1090-2104 ; 0006-291X ; 0006-291X
    ISSN (online) 1090-2104 ; 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2022.08.098
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Commentary on "Ascorbate kills breast cancer cells by rewiring metabolism via redox imbalance and energy crisis" by Ghanem et al. [Free Radic. Biol. Med. 163 (2021) 196-209].

    Halliwell, Barry

    Free radical biology & medicine

    2021  Volume 171, Page(s) 124–125

    MeSH term(s) Ascorbic Acid/pharmacology ; Breast Neoplasms/drug therapy ; Female ; Humans ; Oxidation-Reduction
    Chemical Substances Ascorbic Acid (PQ6CK8PD0R)
    Language English
    Publishing date 2021-05-05
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 807032-5
    ISSN 1873-4596 ; 0891-5849
    ISSN (online) 1873-4596
    ISSN 0891-5849
    DOI 10.1016/j.freeradbiomed.2021.04.029
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