LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 23

Search options

  1. Article ; Online: Disparities in high risk prenatal care adherence along racial and ethnic lines.

    Stegman, Molly M / Lucarelli-Baldwin, Elizabeth / Ural, Serdar H

    Frontiers in global women's health

    2023  Volume 4, Page(s) 1151362

    Abstract: The term "high-risk pregnancy" describes a pregnancy at increased risk for complications due to various maternal or fetal medical, surgical, and/or anatomic issues. In order to best protect the pregnant patient and the fetus, frequent prenatal visits and ...

    Abstract The term "high-risk pregnancy" describes a pregnancy at increased risk for complications due to various maternal or fetal medical, surgical, and/or anatomic issues. In order to best protect the pregnant patient and the fetus, frequent prenatal visits and monitoring are often recommended. Unfortunately, some patients are unable to attend these appointments for various reasons. Moreover, it has been documented that patients from ethnically and racially diverse backgrounds are more likely to miss medical appointments than are Caucasian patients. For instance, a case-control study retrospectively identified the race/ethnicity of patients who no-showed for mammography visits in 2018. Women who no-showed were more likely to be African American than patients who kept their appointments, with an odds ratio of 2.64 (4). Several other studies from several other primary care and specialty disciplines have shown similar results. However, the current research on high-risk obstetric no-shows has focused primarily on
    Language English
    Publishing date 2023-07-25
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2673-5059
    ISSN (online) 2673-5059
    DOI 10.3389/fgwh.2023.1151362
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article: Fetal Metabolic Alkalosis Resulting from Maternal Vomiting.

    Curtin, William M / O'Brien, Emily A / Mauro, Rachel M / Lucarelli-Baldwin, Elizabeth A / Ural, Serdar H / DeAngelis, Christina T

    AJP reports

    2024  Volume 14, Issue 1, Page(s) e48–e50

    Abstract: We describe a pregnant patient with severe compulsive water ingestion and vomiting that lead to metabolic alkalosis and preterm delivery. A 21-year-old patient was hospitalized multiple times throughout pregnancy for symptoms initially thought to be ... ...

    Abstract We describe a pregnant patient with severe compulsive water ingestion and vomiting that lead to metabolic alkalosis and preterm delivery. A 21-year-old patient was hospitalized multiple times throughout pregnancy for symptoms initially thought to be related to hyperemesis gravidarum. Overtime, it became apparent that the patient induced vomiting by rapidly drinking large volumes of water. At 32 weeks' gestation, rapid ingestion of water caused 3 days of vomiting with findings of hyponatremia, hypokalemia, hypochloremia, metabolic alkalosis, and compensatory respiratory acidosis. Fetal monitoring showed minimal variability and recurrent decelerations; subsequent biophysical profile score of 2/10 prompted urgent cesarean section. A male newborn was delivered and cord blood gases reflected neonatal metabolic alkalosis and electrolyte imbalances identical to those of the mother. Compensatory hypoventilation in both mother and fetus were treated with assisted ventilation. With saline administration and repletion of electrolytes, metabolic alkalosis resolved for both patients within days. Metabolic alkalosis was transplacentally acquired by the fetus. This case demonstrates the development of metabolic alkalosis in a pregnant woman caused by vomiting severe enough to prompt preterm delivery for nonreassuring fetal status. It also demonstrates fetal dependence on both placenta and mother to maintain physiologic acid-base and electrolyte balance.
    Language English
    Publishing date 2024-01-23
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2628074-7
    ISSN 2157-7005 ; 2157-6998
    ISSN (online) 2157-7005
    ISSN 2157-6998
    DOI 10.1055/s-0043-1778113
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Persistent breech presentation in a bicornuate uterus.

    Lucarelli, Elizabeth / Khine, Mary / Oyelese, Yinka

    American journal of obstetrics and gynecology

    2020  Volume 224, Issue 1, Page(s) 107

    MeSH term(s) Adult ; Breech Presentation ; Cesarean Section ; Diagnosis, Differential ; Female ; Humans ; Pregnancy ; Pregnancy Complications/diagnosis ; Pregnancy Complications/diagnostic imaging ; Ultrasonography, Prenatal ; Urogenital Abnormalities/diagnosis ; Urogenital Abnormalities/diagnostic imaging ; Uterus/abnormalities ; Uterus/diagnostic imaging
    Language English
    Publishing date 2020-06-18
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80016-8
    ISSN 1097-6868 ; 0002-9378
    ISSN (online) 1097-6868
    ISSN 0002-9378
    DOI 10.1016/j.ajog.2020.06.030
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: A Perspective on the Current Role of Teprotumumab in Treatment of Thyroid Eye Disease.

    Allen, Richard C / Bradley, Elizabeth A / Fante, Robert G / Lucarelli, Mark J

    Ophthalmology

    2021  Volume 128, Issue 8, Page(s) 1125–1128

    MeSH term(s) Antibodies, Monoclonal, Humanized/adverse effects ; Antibodies, Monoclonal, Humanized/economics ; Antibodies, Monoclonal, Humanized/therapeutic use ; Autoimmune Diseases/drug therapy ; Drug Approval ; Drug Costs ; Graves Ophthalmopathy/drug therapy ; Humans ; Immunotherapy/adverse effects ; Immunotherapy/economics ; Immunotherapy/methods ; Receptor, IGF Type 1/immunology ; United States ; United States Food and Drug Administration
    Chemical Substances Antibodies, Monoclonal, Humanized ; Receptor, IGF Type 1 (EC 2.7.10.1) ; teprotumumab (Y64GQ0KC0A)
    Language English
    Publishing date 2021-04-03
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 392083-5
    ISSN 1549-4713 ; 0161-6420
    ISSN (online) 1549-4713
    ISSN 0161-6420
    DOI 10.1016/j.ophtha.2021.03.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Immune response to arbovirus infection in obesity.

    Hameed, Muddassar / Geerling, Elizabeth / Pinto, Amelia K / Miraj, Iqra / Weger-Lucarelli, James

    Frontiers in immunology

    2022  Volume 13, Page(s) 968582

    Abstract: Obesity is a global health problem that affects 650 million people worldwide and leads to diverse changes in host immunity. Individuals with obesity experience an increase in the size and the number of adipocytes, which function as an endocrine organ and ...

    Abstract Obesity is a global health problem that affects 650 million people worldwide and leads to diverse changes in host immunity. Individuals with obesity experience an increase in the size and the number of adipocytes, which function as an endocrine organ and release various adipocytokines such as leptin and adiponectin that exert wide ranging effects on other cells. In individuals with obesity, macrophages account for up to 40% of adipose tissue (AT) cells, three times more than in adipose tissue (10%) of healthy weight individuals and secrete several cytokines and chemokines such as interleukin (IL)-1β, chemokine C-C ligand (CCL)-2, IL-6, CCL5, and tumor necrosis factor (TNF)-α, leading to the development of inflammation. Overall, obesity-derived cytokines strongly affect immune responses and make patients with obesity more prone to severe symptoms than patients with a healthy weight. Several epidemiological studies reported a strong association between obesity and severe arthropod-borne virus (arbovirus) infections such as dengue virus (DENV), chikungunya virus (CHIKV), West Nile virus (WNV), and Sindbis virus (SINV). Recently, experimental investigations found that DENV, WNV, CHIKV and Mayaro virus (MAYV) infections cause worsened disease outcomes in infected diet induced obese (DIO) mice groups compared to infected healthy-weight animals. The mechanisms leading to higher susceptibility to severe infections in individuals with obesity remain unknown, though a better understanding of the causes will help scientists and clinicians develop host directed therapies to treat severe disease. In this review article, we summarize the effects of obesity on the host immune response in the context of arboviral infections. We have outlined that obesity makes the host more susceptible to infectious agents, likely by disrupting the functions of innate and adaptive immune cells. We have also discussed the immune response of DIO mouse models against some important arboviruses such as CHIKV, MAYV, DENV, and WNV. We can speculate that obesity-induced disruption of innate and adaptive immune cell function in arboviral infections ultimately affects the course of arboviral disease. Therefore, further studies are needed to explore the cellular and molecular aspects of immunity that are compromised in obesity during arboviral infections or vaccination, which will be helpful in developing specific therapeutic/prophylactic interventions to prevent immunopathology and disease progression in individuals with obesity.
    MeSH term(s) Animals ; Mice ; Arbovirus Infections ; Obesity ; Mice, Obese ; Chikungunya virus ; West Nile virus ; Immunity
    Language English
    Publishing date 2022-11-18
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2022.968582
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Differing prevalence of microcephaly and macrocephaly in male and female fetuses.

    Brawley, Amalia M / Schaefer, Eric W / Lucarelli, Elizabeth / Ural, Serdar H / Chuang, Cynthia H / Hwang, Wenke / Paul, Ian M / Daymont, Carrie

    Frontiers in global women's health

    2023  Volume 4, Page(s) 1080175

    Abstract: Objective: To compare the proportion of female and male fetuses classified as microcephalic (head circumference [HC] ... 97th percentile) by commonly used sex-neutral growth curves.: Methods: For fetuses evaluated at ...

    Abstract Objective: To compare the proportion of female and male fetuses classified as microcephalic (head circumference [HC] < 3rd percentile) and macrocephalic (>97th percentile) by commonly used sex-neutral growth curves.
    Methods: For fetuses evaluated at a single center, we retrospectively determined the percentile of the first fetal HC measurement between 16 and 0/7 and 21-6/7 weeks using the Hadlock, Intergrowth-21st, and NICHD growth curves. The association between sex and the likelihood of being classified as microcephalic or macrocephalic was evaluated with logistic regression.
    Results: Female fetuses (
    Conclusion: Female fetuses were more likely to be classified as microcephalic, and male fetuses were more likely to be classified as macrocephalic. Sex-specific fetal head circumference growth curves could improve interpretation of fetal head circumference measurements, potentially decreasing over- and under-diagnosis of microcephaly and macrocephaly based on sex, therefore improving guidance for clinical decisions. Additionally, the overall prevalence of atypical head size varied using three growth curves, with the NICHD and Intergrowth-21st curves fitting our population better than the Hadlock curves. The choice of fetal head circumference growth curves may substantially impact clinical care.
    Language English
    Publishing date 2023-02-24
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2673-5059
    ISSN (online) 2673-5059
    DOI 10.3389/fgwh.2023.1080175
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article: Fetal Metabolic Alkalosis Resulting from Maternal Vomiting

    Curtin, William M. / O'Brien, Emily A. / Mauro, Rachel M. / Lucarelli-Baldwin, Elizabeth A. / Ural, Serdar H. / DeAngelis, Christina T.

    American Journal of Perinatology Reports

    2024  Volume 14, Issue 01, Page(s) e48–e50

    Abstract: We describe a pregnant patient with severe compulsive water ingestion and vomiting that lead to metabolic alkalosis and preterm delivery. A 21-year-old patient was hospitalized multiple times throughout pregnancy for symptoms initially thought to be ... ...

    Abstract We describe a pregnant patient with severe compulsive water ingestion and vomiting that lead to metabolic alkalosis and preterm delivery. A 21-year-old patient was hospitalized multiple times throughout pregnancy for symptoms initially thought to be related to hyperemesis gravidarum. Overtime, it became apparent that the patient induced vomiting by rapidly drinking large volumes of water. At 32 weeks' gestation, rapid ingestion of water caused 3 days of vomiting with findings of hyponatremia, hypokalemia, hypochloremia, metabolic alkalosis, and compensatory respiratory acidosis. Fetal monitoring showed minimal variability and recurrent decelerations; subsequent biophysical profile score of 2/10 prompted urgent cesarean section. A male newborn was delivered and cord blood gases reflected neonatal metabolic alkalosis and electrolyte imbalances identical to those of the mother. Compensatory hypoventilation in both mother and fetus were treated with assisted ventilation. With saline administration and repletion of electrolytes, metabolic alkalosis resolved for both patients within days. Metabolic alkalosis was transplacentally acquired by the fetus. This case demonstrates the development of metabolic alkalosis in a pregnant woman caused by vomiting severe enough to prompt preterm delivery for nonreassuring fetal status. It also demonstrates fetal dependence on both placenta and mother to maintain physiologic acid–base and electrolyte balance.
    Keywords pregnancy ; hyperemesis ; alkalosis ; newborn
    Language English
    Publishing date 2024-01-01
    Publisher Thieme Medical Publishers, Inc.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2628074-7
    ISSN 2157-7005 ; 2157-6998
    ISSN (online) 2157-7005
    ISSN 2157-6998
    DOI 10.1055/s-0043-1778113
    Database Thieme publisher's database

    More links

    Kategorien

  8. Article ; Online: The role of food gateways at increasing access to alternative retail food outlets.

    Paré, Elizabeth R / Body, Katherine / Gilstorf, Sarah / Lucarelli, Jennifer

    Translational behavioral medicine

    2019  Volume 9, Issue 5, Page(s) 884–887

    Abstract: Alternative retail food outlets (ARFOs), places where customers purchase foods outside of traditional supermarkets, grocery stores, or food service establishments, may play a role in improving food access in communities that are food deserts. This study ... ...

    Abstract Alternative retail food outlets (ARFOs), places where customers purchase foods outside of traditional supermarkets, grocery stores, or food service establishments, may play a role in improving food access in communities that are food deserts. This study was conducted to understand the way ARFOs function to support food systems and access to fruits and vegetables in low-resource communities. This qualitative study conducted 16 interviews with managers, volunteers, and customers in two produce market ARFOs in a primarily minority urban community. Findings demonstrate that produce market volunteers and customers may act as "food gateways," or an intermediate step in accessing food resources, in their communities by providing transportation to ARFOs, distributing food to isolated community members, and providing advocacy support to ARFOs. Interventions to increase food equity and access via ARFOs should examine how people serving as "food gateways" can assist in improving food access as intermediaries.
    MeSH term(s) Commerce ; Food Supply ; Fruit ; Humans ; Interviews as Topic ; Minority Groups ; Urban Population ; Vegetables
    Language English
    Publishing date 2019-09-05
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 2586893-7
    ISSN 1613-9860 ; 1869-6716
    ISSN (online) 1613-9860
    ISSN 1869-6716
    DOI 10.1093/tbm/ibz089
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Mechanical Ventilation in Pregnancy Due to COVID-19: A Cohort of Three Cases.

    Lucarelli, Elizabeth / Behn, Claudia / Lashley, Susan / Smok, Dorothy / Benito, Carlos / Oyelese, Yinka

    American journal of perinatology

    2020  Volume 37, Issue 10, Page(s) 1066–1069

    Abstract: We describe our experience with three pregnant women with novel coronavirus disease 2019 (COVID-19) who required mechanical ventilation. Recent data suggest a mortality of 88% in nonpregnant patients with COVID-19 who require intubation and mechanical ... ...

    Abstract We describe our experience with three pregnant women with novel coronavirus disease 2019 (COVID-19) who required mechanical ventilation. Recent data suggest a mortality of 88% in nonpregnant patients with COVID-19 who require intubation and mechanical ventilation. The three women we report were intubated and mechanically ventilated during pregnancy due to respiratory failure and pneumonia resulting from COVID-19. After several days of ventilation, all three were successfully weaned off mechanical ventilation and extubated, and are continuing their pregnancies with no demonstrable adverse effects. Our experience suggests that the mortality in pregnant women with COVID-19 requiring mechanical ventilation is not necessarily as high as in nonpregnant patients with COVID-19. KEY POINTS: · Coronavirus disease 2019 (COVID-19) is now a pandemic.. · COVID-19 may cause pneumonia or respiratory failure in pregnant women.. · Approximately 5% of women with COVID-19 will develop severe or critical disease.. · Mechanical ventilation in pregnant women may not necessarily result in high mortality rates..
    MeSH term(s) Adult ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Coronavirus Infections/diagnosis ; Coronavirus Infections/therapy ; Emergency Service, Hospital ; Female ; Gestational Age ; Humans ; Middle Aged ; Monitoring, Physiologic/methods ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/therapy ; Pregnancy ; Pregnancy Complications, Infectious/therapy ; Pregnancy Complications, Infectious/virology ; Pregnancy Outcome ; Pregnancy, High-Risk ; Respiration, Artificial/methods ; Respiratory Insufficiency/etiology ; Respiratory Insufficiency/therapy ; Risk Assessment ; Sampling Studies
    Keywords covid19
    Language English
    Publishing date 2020-06-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605671-4
    ISSN 1098-8785 ; 0735-1631
    ISSN (online) 1098-8785
    ISSN 0735-1631
    DOI 10.1055/s-0040-1713664
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article: Qualitative Focus Groups: Perceived Influences on Decision Making About Diet and Physical Activity Among Hispanic/Latino Participants.

    Paré, Elizabeth R / Body, Katherine / Gilstorf, Sarah / Lucarelli, Jennifer

    Health promotion practice

    2018  Volume 20, Issue 6, Page(s) 868–879

    Abstract: Disparities in minority health are strongly associated with reduced access to culturally familiar food and physical activity opportunities. This qualitative study explores a Midwest, urban Hispanic/Latino community, the members' experiences with their ... ...

    Abstract Disparities in minority health are strongly associated with reduced access to culturally familiar food and physical activity opportunities. This qualitative study explores a Midwest, urban Hispanic/Latino community, the members' experiences with their multidimensional environment and its influence on their nutrition and physical activity choices. Using the principles of community-based participatory research in collaboration with a trusted, local Hispanic/Latino community agency, we conducted five bilingual focus groups with a total of 46 self-selected participants (44 women and 2 men). We find that one's perception of the environmental factors of access, convenience, affordability, and safety influence food and physical activity decision making. Findings can be used to inform interventions to enhance culturally appropriate outreach, increase food equity, and decrease health disparities.
    MeSH term(s) Adult ; Attitude to Health/ethnology ; Community-Based Participatory Research ; Diet/ethnology ; Exercise/psychology ; Female ; Focus Groups ; Health Behavior/ethnology ; Health Status ; Health Status Disparities ; Hispanic Americans/statistics & numerical data ; Humans ; Male ; Middle Aged ; Qualitative Research
    Language English
    Publishing date 2018-06-06
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 2036801-X
    ISSN 1552-6372 ; 1524-8399
    ISSN (online) 1552-6372
    ISSN 1524-8399
    DOI 10.1177/1524839918779382
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top