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  1. Article ; Online: Randomized, controlled trials in critical care: an expert interview with John J. Marini, MD [interviewed by Antonios Liolios, MD].

    Marini, John J

    MedGenMed : Medscape general medicine

    2003  Volume 5, Issue 2, Page(s) 26

    MeSH term(s) Critical Care/trends ; Evidence-Based Medicine/trends ; Humans ; Practice Guidelines as Topic ; Randomized Controlled Trials as Topic/contraindications
    Language English
    Publishing date 2003-06-3
    Publishing country United States
    Document type Comparative Study ; Interview
    ISSN 1531-0132
    ISSN (online) 1531-0132
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Detecting end-tidal hyperinflation.

    Marini, John J

    Intensive care medicine

    2024  

    Language English
    Publishing date 2024-04-02
    Publishing country United States
    Document type Editorial
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-024-07379-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Mechanical ventilation & ventricular assist devices

    Marini, John J.

    (Critical care clinics ; volume 34, number 3 (July 2018))

    2018  

    Author's details editors John J. Marini, Srinivas Murali
    Series title Critical care clinics ; volume 34, number 3 (July 2018)
    Collection
    Language English
    Size xiv Seiten, Seite 314-492, Illustrationen
    Publisher Elsevier
    Publishing place Philadelphia, Pennsylvania
    Publishing country United States
    Document type Book
    HBZ-ID HT019773496
    ISBN 978-0-323-61060-5 ; 0-323-61060-9
    Database Catalogue ZB MED Medicine, Health

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  4. Book: Textbook of critical care

    Vincent, Jean-Louis / Moore, Frederick A. / Bellomo, Rinaldo / Marini, John J.

    2024  

    Title variant Critical care
    Author's details Jean-Louis Vincent, Edward Abraham, Patrick Kochanek, Frederick A. Moore, Mitchell P. Fink
    Keywords Critical Care ; Intensive Care Units ; Critical care medicine
    Subject code 616.028
    Language English
    Size xxviii, 1423 Seiten, Illustrationen, 29 cm
    Edition 8th edition
    Publisher Elsevier
    Publishing place Amsterdam
    Publishing country Netherlands
    Document type Book
    Accompanying material Zugang zu Enhanced Digital Version über Code
    HBZ-ID HT021433254
    ISBN 978-0-323-75929-8 ; 9780323759304 ; 0-323-75929-7 ; 0323759300
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: Can We Always Trust the Wisdom of the Body?

    Marini, John J

    Critical care medicine

    2022  Volume 50, Issue 8, Page(s) 1268–1271

    MeSH term(s) Judgment ; Knowledge ; Trust
    Language English
    Publishing date 2022-07-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000005022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The Respiratory Mechanics of COVID-19 Acute Respiratory Distress Syndrome-Lessons Learned?

    Kummer, Rebecca L / Marini, John J

    Journal of clinical medicine

    2024  Volume 13, Issue 7

    Abstract: Acute respiratory distress syndrome (ARDS) is a well-defined clinical entity characterized by the acute onset of diffuse pulmonary injury and hypoxemia not explained by fluid overload. The COVID-19 pandemic brought about an unprecedented volume of ... ...

    Abstract Acute respiratory distress syndrome (ARDS) is a well-defined clinical entity characterized by the acute onset of diffuse pulmonary injury and hypoxemia not explained by fluid overload. The COVID-19 pandemic brought about an unprecedented volume of patients with ARDS and challenged our understanding and clinical approach to treatment of this clinical syndrome. Unique to COVID-19 ARDS is the disruption and dysregulation of the pulmonary vascular compartment caused by the SARS-CoV-2 virus, which is a significant cause of hypoxemia in these patients. As a result, gas exchange does not necessarily correlate with respiratory system compliance and mechanics in COVID-19 ARDS as it does with other etiologies. The purpose of this review is to relate the mechanics of COVID-19 ARDS to its underlying pathophysiologic mechanisms and outline the lessons we have learned in the management of this clinic syndrome.
    Language English
    Publishing date 2024-03-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13071833
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Bedside Detection of End-Tidal Hyperinflation in Acute Respiratory Distress Syndrome.

    Marini, John J / Selickman, John

    Annals of the American Thoracic Society

    2022  Volume 19, Issue 11, Page(s) 1791–1795

    MeSH term(s) Humans ; Respiratory Distress Syndrome ; Tidal Volume ; Respiration, Artificial
    Language English
    Publishing date 2022-07-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202205-460PS
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Optimized ventilation power to avoid VILI.

    Thornton, Lauren T / Marini, John J

    Journal of intensive care

    2023  Volume 11, Issue 1, Page(s) 57

    Abstract: The effort to minimize VILI risk must be multi-pronged. The need to adequately ventilate, a key determinant of hazardous power, is reduced by judicious permissive hypercapnia, reduction of innate oxygen demand, and by prone body positioning that promotes ...

    Abstract The effort to minimize VILI risk must be multi-pronged. The need to adequately ventilate, a key determinant of hazardous power, is reduced by judicious permissive hypercapnia, reduction of innate oxygen demand, and by prone body positioning that promotes both efficient pulmonary gas exchange and homogenous distributions of local stress. Modifiable ventilator-related determinants of lung protection include reductions of tidal volume, plateau pressure, driving pressure, PEEP, inspiratory flow amplitude and profile (using longer inspiration to expiration ratios), and ventilation frequency. Underappreciated conditional cofactors of importance to modulate the impact of local specific power may include lower vascular pressures and blood flows. Employed together, these measures modulate ventilation power with the intent to avoid VILI while achieving clinically acceptable targets for pulmonary gas exchange.
    Language English
    Publishing date 2023-11-20
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2739853-5
    ISSN 2052-0492
    ISSN 2052-0492
    DOI 10.1186/s40560-023-00706-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Chest wall loading in the ICU: pushes, weights, and positions.

    Selickman, John / Marini, John J

    Annals of intensive care

    2022  Volume 12, Issue 1, Page(s) 103

    Abstract: Clinicians monitor mechanical ventilatory support using airway pressures-primarily the plateau and driving pressure, which are considered by many to determine the safety of the applied tidal volume. These airway pressures are influenced not only by the ... ...

    Abstract Clinicians monitor mechanical ventilatory support using airway pressures-primarily the plateau and driving pressure, which are considered by many to determine the safety of the applied tidal volume. These airway pressures are influenced not only by the ventilator prescription, but also by the mechanical properties of the respiratory system, which consists of the series-coupled lung and chest wall. Actively limiting chest wall expansion through external compression of the rib cage or abdomen is seldom performed in the ICU. Recent literature describing the respiratory mechanics of patients with late-stage, unresolving, ARDS, however, has raised awareness of the potential diagnostic (and perhaps therapeutic) value of this unfamiliar and somewhat counterintuitive practice. In these patients, interventions that reduce resting lung volume, such as loading the chest wall through application of external weights or manual pressure, or placing the torso in a more horizontal position, have unexpectedly improved tidal compliance of the lung and integrated respiratory system by reducing previously undetected end-tidal hyperinflation. In this interpretive review, we first describe underappreciated lung and chest wall interactions that are clinically relevant to both normal individuals and to the acutely ill who receive ventilatory support. We then apply these physiologic principles, in addition to published clinical observation, to illustrate the utility of chest wall modification for the purposes of detecting end-tidal hyperinflation in everyday practice.
    Language English
    Publishing date 2022-11-08
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2617094-2
    ISSN 2110-5820
    ISSN 2110-5820
    DOI 10.1186/s13613-022-01076-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Dealing With the CARDS of COVID-19.

    Marini, John J

    Critical care medicine

    2020  Volume 48, Issue 8, Page(s) 1239–1241

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; Respiratory Distress Syndrome ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-12
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000004427
    Database MEDical Literature Analysis and Retrieval System OnLINE

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