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  1. Article: Recombination in bdelloid rotifer genomes: asexuality, transfer and stress.

    Wilson, Christopher G / Pieszko, Tymoteusz / Nowell, Reuben W / Barraclough, Timothy G

    Trends in genetics : TIG

    2024  

    Abstract: Bdelloid rotifers constitute a class of microscopic animals living in freshwater habitats worldwide. Several strange features of bdelloids have drawn attention: their ability to tolerate desiccation and other stresses, a lack of reported males across the ...

    Abstract Bdelloid rotifers constitute a class of microscopic animals living in freshwater habitats worldwide. Several strange features of bdelloids have drawn attention: their ability to tolerate desiccation and other stresses, a lack of reported males across the clade despite centuries of study, and unusually high numbers of horizontally acquired, non-metazoan genes. Genome sequencing is transforming our understanding of their lifestyle and its consequences, while in turn providing wider insights about recombination and genome organisation in animals. Many questions remain, not least how to reconcile apparent genomic signatures of sex with the continued absence of reported males, why bdelloids have so many horizontally acquired genes, and how their remarkable ability to survive stress interacts with recombination and other genomic processes.
    Language English
    Publishing date 2024-03-07
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 619240-3
    ISSN 1362-4555 ; 0168-9525 ; 0168-9479
    ISSN (online) 1362-4555
    ISSN 0168-9525 ; 0168-9479
    DOI 10.1016/j.tig.2024.02.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Better Late Than Never: Definitive Anatomic Repair of Dextro-Transposition of the Great Arteries.

    Bahrami, Asma / Kostelyna, Stefan P / Dugger, Samuel J / Broda, Christopher R / Ermis, Peter R / Caldarone, Christopher A / Lam, Wilson W

    JACC. Case reports

    2024  Volume 29, Issue 7, Page(s) 102269

    Abstract: We present a case of anatomic repair of dextro-transposition of the great arteries (d-TGA) with ventricular septal defect (VSD) in a 55-year-old man who presented with acute heart failure. This case highlights the importance of multimodal imaging and ... ...

    Abstract We present a case of anatomic repair of dextro-transposition of the great arteries (d-TGA) with ventricular septal defect (VSD) in a 55-year-old man who presented with acute heart failure. This case highlights the importance of multimodal imaging and multidisciplinary involvement in developing a comprehensive surgical and medical plan for adults with congenital heart disease. We think this is the oldest reported patient undergoing anatomic surgical repair of d-TGA with VSD.
    Language English
    Publishing date 2024-02-27
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2666-0849
    ISSN (online) 2666-0849
    DOI 10.1016/j.jaccas.2024.102269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The independent and joint associations of cardiorespiratory fitness and adiposity with cardiometabolic risk factors and metabolic syndrome in United States college students.

    Bopp, Christopher M / Wilson, Oliver W A

    Journal of American college health : J of ACH

    2022  Volume 72, Issue 3, Page(s) 768–775

    Abstract: ... ...

    Abstract Objective
    MeSH term(s) Male ; Adult ; Humans ; Female ; Metabolic Syndrome/epidemiology ; Metabolic Syndrome/prevention & control ; Cardiorespiratory Fitness ; Adiposity ; Cardiometabolic Risk Factors ; Students ; Universities ; Risk Factors ; Obesity ; Physical Fitness
    Language English
    Publishing date 2022-04-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604907-2
    ISSN 1940-3208 ; 0744-8481
    ISSN (online) 1940-3208
    ISSN 0744-8481
    DOI 10.1080/07448481.2022.2057191
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  4. Article ; Online: Fire sparks upslope range shifts of North Cascades plant species.

    Wilson, Rachel N / Kopp, Christopher W / Hille Ris Lambers, Janneke / Angert, Amy L

    Ecology

    2024  Volume 105, Issue 3, Page(s) e4242

    Abstract: As ongoing climate change drives suitable habitats to higher elevations, species ranges are predicted to follow. However, observed range shifts have been surprisingly variable, with most species differing in rates of upward shift and others failing to ... ...

    Abstract As ongoing climate change drives suitable habitats to higher elevations, species ranges are predicted to follow. However, observed range shifts have been surprisingly variable, with most species differing in rates of upward shift and others failing to shift at all. Disturbances such as fires could play an important role in accelerating range shifts by facilitating recruitment in newly suitable habitats (leading edges) and removing adults from areas no longer suited for regeneration (trailing edges). To date, empirical evidence that fires interact with climate change to mediate elevational range shifts is scarce. Resurveying historical plots in areas that experienced climate change and fire disturbance between surveys provides an exciting opportunity to fill this gap. To investigate whether species have tended to shift upslope and if shifts depend on fires, we resurveyed historical vegetation plots in North Cascades National Park, Washington, USA, an area that has experienced warming, drying, and multiple fires since the original surveys in 1983. We quantified range shifts by synthesizing across two lines of evidence: (1) displacement at range edges and the median elevation of species occurrences, and (2) support for the inclusion of interactions among time, fire and elevation in models of species presence with elevation. Among species that experienced fire since the original survey, a plurality expanded into new habitats at their upper edge. In contrast, a plurality of species not experiencing fire showed no evidence of shifts, with the remainder exhibiting responses that were variable in magnitude and direction. Our results suggest that fires can facilitate recruitment at leading edges, while species in areas free of disturbance are more likely to experience stasis.
    MeSH term(s) Forests ; Ecosystem ; Trees/physiology ; Climate Change ; Washington
    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2010140-5
    ISSN 1939-9170 ; 0012-9658
    ISSN (online) 1939-9170
    ISSN 0012-9658
    DOI 10.1002/ecy.4242
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  5. Article ; Online: A method for measuring meaningful physiological variables in fish blood without surgical cannulation.

    Davison, William George / Cooper, Christopher A / Sloman, Katherine A / Wilson, Rod W

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 899

    Abstract: Gaining meaningful blood samples from water-breathing fish is a significant challenge. Two main methods typically used are grab 'n' stab and surgical cannulation. Both methods have benefits, but also significant limitations under various scenarios. Here ... ...

    Abstract Gaining meaningful blood samples from water-breathing fish is a significant challenge. Two main methods typically used are grab 'n' stab and surgical cannulation. Both methods have benefits, but also significant limitations under various scenarios. Here we present a method of blood sampling laboratory fish involving gradual induction of anaesthesia within their home tank, avoiding physical struggling associated with capture, followed by rapid transfer to a gill irrigation system to maintain artificial ventilation via adequate gill water flow and then followed by sampling the caudal vasculature. This method negates many blood chemistry disturbances associated with grab 'n' stab (i.e., low pH and oxygen, elevated lactate, CO
    MeSH term(s) Animals ; Fishes/physiology ; Blood Specimen Collection/methods ; Phlebotomy ; Catheterization ; Water ; Hydrogen-Ion Concentration
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2023-01-17
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-28061-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Is epicardial adipose tissue a key pathophysiologic target in heart failure with preserved ejection?

    Martens, Pieter / Nguyen, Christopher / Tang, W H Wilson

    Journal of molecular and cellular cardiology

    2022  Volume 171, Page(s) 69–70

    MeSH term(s) Adipose Tissue ; Heart Failure ; Humans ; Pericardium ; Stroke Volume
    Language English
    Publishing date 2022-07-19
    Publishing country England
    Document type Letter
    ZDB-ID 80157-4
    ISSN 1095-8584 ; 0022-2828
    ISSN (online) 1095-8584
    ISSN 0022-2828
    DOI 10.1016/j.yjmcc.2022.07.003
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  7. Article ; Online: Ketogenic Diet in Heart Failure: Fact or Fiction?

    Kodur, Nandan / Yurista, Salva / Province, Valesha / Rueth, Emma / Nguyen, Christopher / Tang, W H Wilson

    JACC. Heart failure

    2023  Volume 11, Issue 7, Page(s) 838–844

    MeSH term(s) Humans ; Diet, Ketogenic ; Heart Failure
    Language English
    Publishing date 2023-05-26
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2023.05.009
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  8. Article: The spectral composition of a white light influences its attractiveness to

    Wilson, Roksana / Cooper, Christopher E C / Meah, Rochelle J / Wakefield, Andrew / Roberts, Nicholas W / Jones, Gareth

    Ecology and evolution

    2023  Volume 13, Issue 1, Page(s) e9714

    Abstract: Insect attraction to artificial light can potentially facilitate disease transmission by increasing contact between humans and vectors. Previous research has identified specific wavelength bands, such as yellow and red, that are unattractive to biting ... ...

    Abstract Insect attraction to artificial light can potentially facilitate disease transmission by increasing contact between humans and vectors. Previous research has identified specific wavelength bands, such as yellow and red, that are unattractive to biting flies. However, narrow-band, non-white lights are unsuitable for home lighting use as their very poor color rendering is often considered aesthetically undesirable. The creation of a white light that is unattractive to insects has so far remained elusive. White light can be created by combining a number of narrow-band light-emitting diodes (LEDs). Through choice chamber experiments on
    Language English
    Publishing date 2023-01-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2635675-2
    ISSN 2045-7758
    ISSN 2045-7758
    DOI 10.1002/ece3.9714
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  9. Article ; Online: Stairway to memory: Left-hemispheric alpha dynamics index the progressive loading of items into a short-term store.

    Wiesman, Alex I / Christopher-Hayes, Nicholas J / Wilson, Tony W

    NeuroImage

    2021  Volume 235, Page(s) 118024

    Abstract: The encoding, maintenance, and subsequent retrieval of memories over short time intervals is an essential cognitive function. Load effects on the neural dynamics supporting the maintenance of short-term memories have been well studied, but experimental ... ...

    Abstract The encoding, maintenance, and subsequent retrieval of memories over short time intervals is an essential cognitive function. Load effects on the neural dynamics supporting the maintenance of short-term memories have been well studied, but experimental design limitations have hindered the study of similar effects during the encoding of information into online memory stores. Theoretically, the active encoding of complex visual stimuli into memory must also recruit neural resources in a manner that scales with memory load. Understanding the neural systems supporting this encoding load effect is of particular importance, as some patient populations exhibit difficulties specifically with the encoding, and not the maintenance, of short-term memories. Using magnetoencephalography, a visual sequence memory paradigm, and a novel encoding slope analysis, we provide evidence for a left-lateralized network of regions, oscillating in the alpha frequency range, that exhibit a progressive loading effect of complex visual stimulus information during memory encoding. This progressive encoding load effect significantly tracked the eventual retrieval of item-order memories at the single trial level, and neural activity in these regions was functionally dissociated from that of earlier visual networks. These findings suggest that the active encoding of stimulus information into short-term stores recruits a left-lateralized network of frontal, parietal, and temporal regions, and might be susceptible to modulation (e.g., using non-invasive stimulation) in the alpha band.
    MeSH term(s) Adult ; Alpha Rhythm/physiology ; Brain/physiology ; Female ; Humans ; Magnetic Resonance Imaging ; Magnetoencephalography ; Male ; Memory, Short-Term/physiology ; Temporal Lobe/physiology ; Visual Perception/physiology
    Language English
    Publishing date 2021-04-06
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 1147767-2
    ISSN 1095-9572 ; 1053-8119
    ISSN (online) 1095-9572
    ISSN 1053-8119
    DOI 10.1016/j.neuroimage.2021.118024
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  10. Article ; Online: Altered age-related alpha and gamma prefrontal-occipital connectivity serving distinct cognitive interference variants.

    Arif, Yasra / Wiesman, Alex I / Christopher-Hayes, Nicholas / Okelberry, Hannah J / Johnson, Hallie J / Willett, Madelyn P / Wilson, Tony W

    NeuroImage

    2023  Volume 280, Page(s) 120351

    Abstract: The presence of conflicting stimuli adversely affects behavioral outcomes, which could either be at the level of stimulus (Flanker), response (Simon), or both (Multisource). Briefly, flanker interference involves conflicting stimuli requiring selective ... ...

    Abstract The presence of conflicting stimuli adversely affects behavioral outcomes, which could either be at the level of stimulus (Flanker), response (Simon), or both (Multisource). Briefly, flanker interference involves conflicting stimuli requiring selective attention, Simon interference is caused by an incongruity between the spatial location of the task-relevant stimulus and prepotent motor mapping, and multisource is combination of both. Irrespective of the variant, interference resolution necessitates cognitive control to filter irrelevant information and allocate neural resources to task-related goals. Though previously studied in healthy young adults, the direct quantification of changes in oscillatory activity serving such cognitive control and associated inter-regional interactions in healthy aging are poorly understood. Herein, we used an adapted version of the multisource interference task and magnetoencephalography to investigate age-related alterations in the neural dynamics governing both divergent and convergent cognitive interference in 78 healthy participants (age range: 20-66 years). We identified weaker alpha connectivity between bilateral visual and right dorsolateral prefrontal cortices (DLPFC) and left dorsomedial prefrontal cortices (dmPFC), as well as weaker gamma connectivity between bilateral occipital regions and the right dmPFC during flanker interference with advancing age. Further, an age-related decrease in gamma power was observed in the left cerebellum and parietal region for Simon and differential interference effects (i.e., flanker-Simon), respectively. Moreover, the superadditivity model showed decreased gamma power in the right temporoparietal junction (TPJ) with increasing age. Overall, our findings suggest age-related declines in the engagement of top-down attentional control secondary to reduced alpha and gamma coupling between prefrontal and occipital cortices.
    MeSH term(s) Young Adult ; Humans ; Adult ; Middle Aged ; Aged ; Cerebellum ; Dorsolateral Prefrontal Cortex ; Gamma Rays ; Head ; Cognition
    Language English
    Publishing date 2023-09-01
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1147767-2
    ISSN 1095-9572 ; 1053-8119
    ISSN (online) 1095-9572
    ISSN 1053-8119
    DOI 10.1016/j.neuroimage.2023.120351
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