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Article: Deposition and Optical Characterization of Sputter Deposited p-Type Delafossite CuGaO

Bharath, Akash Hari / Saikumar, Ashwin Kumar / Sundaram, Kalpathy B

2024 Volume 17, Issue 7

Abstract: ... ...

Abstract	CuGaO
Language	English
Publishing date	2024-04-01
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2487261-1
ISSN	1996-1944
ISSN	1996-1944
DOI	10.3390/ma17071609
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Physicochemical characterization of elephant apple (Dillenia indica L.) fruit and its mass and volume modeling using computer vision

Saikumar, Akuleti / Nickhil, C. / Badwaik, Laxmikant S.

Scientia Horticulturae. 2023 Apr., v. 314 p.111947-

2023

Abstract: The elephant apple (Dillenia indica L.) is an underutilized fruit and a potential source of many nutrients. The variations in the mass and volume of fruits are highly dependent on their physical properties. This relation is used to design precise post- ... ...

Abstract	The elephant apple (Dillenia indica L.) is an underutilized fruit and a potential source of many nutrients. The variations in the mass and volume of fruits are highly dependent on their physical properties. This relation is used to design precise post-harvest machinery and analyze fruit quality. The work aims to study the physicochemical properties and predict the correlation of mass and volume with various physical properties measured by image processing techniques through single and multivariable regression models such as linear, quadratic, rational, and exponential, respectively. The total phenolic content, flavonoid, and antioxidant activity of elephant apple powder are 1.2 mg GAE/g, 353.58 mg QE/g, and 5.74 mg GAEAC/g, respectively. Among single-variable models, the length-based rational model was best suited for predicting the mass and volume of elephant apples with high R² values of 0.930 and 0.924, respectively. For mass and volume of combined physical properties, rational and exponential models showed the best fit with the R² values of 0.935 and 0.950 with RMSE values of 18.196 and 15.638. Thus, the correlation between the mass and volume of elephant apples with their physical characteristics resulted in a quicker, more accurate, and more precise grading system.
Keywords	Dillenia indica ; antioxidant activity ; computer vision ; flavonoids ; fruit quality ; fruits ; models ; Elephant apple ; Total phenolic content ; Total flavonoids ; Physical properties ; Ap ; P ; W ; L ; X ; a ; RMSE ; SD ; TSS ; TA ; AA
Language	English
Dates of publication	2023-04
Publishing place	Elsevier B.V.
Document type	Article ; Online
ZDB-ID	185557-8
ISSN	0304-4238
ISSN	0304-4238
DOI	10.1016/j.scienta.2023.111947
Database	NAL-Catalogue (AGRICOLA)

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Article: Herpes Virus Pseudotumor in a Patient with HIV Immunosuppression.

York, Daniel / Patel, Pavan / Saikumar, Smera

Case reports in obstetrics and gynecology

2022 Volume 2022, Page(s) 3109331

Abstract: Background: In rare cases, HSV infections can present as pseudotumors that are often mistaken as malignancies in patients with an uncontrolled HIV infection. Herpes simplex virus type 2 (HSV-2) infection rates range from 60% to 90% in individuals ... ...

Abstract	Background: In rare cases, HSV infections can present as pseudotumors that are often mistaken as malignancies in patients with an uncontrolled HIV infection. Herpes simplex virus type 2 (HSV-2) infection rates range from 60% to 90% in individuals coinfected with HIV. Conclusion: Atypical HSV pseudotumors should be considered in the differential diagnosis for an immunosuppressed patient who presents with a genital mass lesion.
Language	English
Publishing date	2022-07-07
Publishing country	United States
Document type	Case Reports
ZDB-ID	2627654-9
ISSN	2090-6692 ; 2090-6684
ISSN (online)	2090-6692
ISSN	2090-6684
DOI	10.1155/2022/3109331
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Article: Retrocardiac Opacities Detected on Chest Radiographs and their Imaging Workup: A Pictorial Review

Saikumar, Divya / Ramachandran, K. / Zunimol, P.K.M.

Indographics

2023 Volume 02, Issue 01, Page(s) 28–38

Abstract: The retrocardiac space is a tricky area in the chest radiograph, where abnormal densities are frequently missed out. Lesions in this area produce late pressure symptoms compared with those in the upper mediastinum. Early detection and proper evaluation ... ...

Abstract	The retrocardiac space is a tricky area in the chest radiograph, where abnormal densities are frequently missed out. Lesions in this area produce late pressure symptoms compared with those in the upper mediastinum. Early detection and proper evaluation of retrocardiac opacities can help the radiologist to establish the diagnosis before clinical signs and symptoms become apparent. We present a case series of 10 patients with incidentally detected retrocardiac opacities in the frontal chest radiograph, which were further evaluated with other imaging modalities such as lateral chest radiograph, computed tomography (CT) or magnetic resonance imaging (MRI) to establish the diagnosis. The final diagnosis included congenital conditions like esophageal duplication cyst and bronchogenic cyst; inflammatory conditions like spondylodiscitis, lung abscess, and lobar pneumonia; vascular conditions like aortic aneurysm; diaphragmatic pathologies like hiatus hernia; and rare tumors like cardiac papillary fibroelastoma, pulmonary neuroendocrine tumor, and ganglioneuroma. Cardinal signs that aid in the diagnosis of retrocardiac opacities are also discussed.
Keywords	retrocardiac opacities ; retrocardiac space ; chest radiograph ; retrocardiac sail sign ; cardiac shadow
Language	English
Publishing date	2023-01-01
Publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
Publishing place	Stuttgart ; New York
Document type	Article
ISSN	2583-8229
ISSN (online)	2583-8229
DOI	10.1055/s-0043-1771239
Database	Thieme publisher's database

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Article ; Online: A Study on Subsite-specific Prevalence of Candidiasis in Head and Neck Cancer Patients and its Antifungal Susceptibility Pattern

Neethu Babu / Chitralekha Saikumar / Jomon Raphael Chalissery

Journal of Clinical and Diagnostic Research, Vol 17, Iss 10, Pp 09-

A Cross-sectional Study

2023 Volume 13

Abstract: ... significant (p-value <0.05). All C. albicans strains were sensitive to ... ...

Abstract	Introduction: The incidence of candidiasis can vary across various subsites within the head and neck region and is associated with various co-morbidities and risk factors. The increase in the incidence of resistant Non-albicans Candida (NAC) species among these patients and the limited number of available antifungal agents make treatment difficult. A better understanding of the subsite-specific prevalence of candidiasis and its antifungal susceptibility is crucial in enhancing effective control and treatment. Aim: To determine the subsite-specific prevalence of candidiasis among Head and Neck Cancer (HNC) patients undergoing radiotherapy. Materials and Methods: A cross-sectional study was conducted on patients undergoing therapy for head and neck malignancies at the Department of Radiation Oncology, Amala Institute of Medical Sciences, Thrissur, Kerala, India over a four-year period (January 2019 to December 2022). A total of 276 patients aged 18 to 85 years with squamous cell carcinoma were included. Oral samples were collected from patients who developed candidiasis, and co-morbidities and risk factors were documented. Candida species were isolated and identified. Antifungal susceptibility was determined using the VITEK system, and fluconazole susceptibility was compared with the standard disc diffusion method. Data were entered into an Excel sheet and analysed using Statistical Package for the Social Sciences (SPSS) software. Results: Pharynx was the most frequent site of head and neck malignancy, accounting for 104 cases (37.7%), followed by the oral cavity with 83 cases (30.1%). Among patients with malignancies in the pharyngeal region, a high rate of Candida infection was observed in 42 (43.3%) out of 97 cases. Candida species isolated included C. albicans (56, 57.7%), C. tropicalis (26, 26.8%), C. krusei (8, 8.3%), C. glabrata (3, 3.1%), and C. parapsilosis (4, 4.1%). Sixty-five patients (23.5%) had diabetes, which was statistically significant (p-value <0.05). All C. albicans strains were sensitive to ...
Keywords	candida albicans ; candida glabrata ; fluconazole ; pharynx ; radiotherapy ; voriconazole ; Medicine ; R
Subject code	610
Language	English
Publishing date	2023-10-01T00:00:00Z
Publisher	JCDR Research and Publications Private Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A Gastroenterologist's Guide to Care Transitions in Cystic Fibrosis from Pediatrics to Adult Care.

Patel, Dhiren / Baliss, Michelle / Saikumar, Pavithra / Numan, Laith / Teckman, Jeffrey / Hachem, Christine

International journal of molecular sciences

2023 Volume 24, Issue 21

Abstract: Cystic Fibrosis is a chronic disease affecting multiple systems, including the GI tract. Clinical manifestation in patients can start as early as infancy and vary across different age groups. With the advent of new, highly effective modulators, the life ... ...

Abstract	Cystic Fibrosis is a chronic disease affecting multiple systems, including the GI tract. Clinical manifestation in patients can start as early as infancy and vary across different age groups. With the advent of new, highly effective modulators, the life expectancy of PwCF has improved significantly. Various GI aspects of CF care, such as nutrition, are linked to an overall improvement in morbidity, lung function and the quality of life of PwCF. The variable clinical presentations and management of GI diseases in pediatrics and adults with CF should be recognized. Therefore, it is necessary to ensure efficient transfer of information between pediatric and adult providers for proper continuity of management and coordination of care at the time of transition. The transition of care is a challenging process for both patients and providers and currently there are no specific tools for GI providers to help ensure a smooth transition. In this review, we aim to highlight the crucial features of GI care at the time of transition and provide a checklist that can assist in ensuring an effective transition and ease the challenges associated with it.
MeSH term(s)	Humans ; Adult ; Child ; Cystic Fibrosis/therapy ; Cystic Fibrosis/complications ; Patient Transfer ; Quality of Life ; Gastroenterologists ; Gastrointestinal Diseases/complications
Language	English
Publishing date	2023-10-30
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms242115766
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Article: Genetic divergence analysis in maintainer (B) and restorer (R) lines of pearl millet (Pennisetum glaucum (L.) R. Br.)

Saikumar, P. / Priya, M. Shanthi / Shanthi, P. / Latha, P.

Electronic journal of plant breeding. 2021 Dec., v. 12, no. 4

2021

Abstract: The present experiment was performed to analyze genetic diversity among 37 parental lines of pearl millet includes 10 maintainer and 27 restorer lines for grain yield and its attributes through Mahalanobis D² statistics. All the 37 genotypes were ... ...

Abstract	The present experiment was performed to analyze genetic diversity among 37 parental lines of pearl millet includes 10 maintainer and 27 restorer lines for grain yield and its attributes through Mahalanobis D² statistics. All the 37 genotypes were assigned into eight different clusters. Cluster II was the largest one composed of 12 genotypes subsequently cluster V with eight genotypes, cluster VII contains seven genotypes and cluster I had fve genotypes. Whereas, clusters III, IV and VIII were solitary. High order of genetic divergence was noticed between cluster VI and VII (109.29), followed by cluster VII and VIII (72.27), cluster III and VII (66.65). Hybridization between genotypes from divergent clusters and with the best mean performance for productivity traits could be benefcial for developing promising hybrids. The trait 1000 grain weight contributed a maximum (25.53%) towards genetic diversity followed by days to 50% fowering (19.22%), panicle girth (13.21%), panicle length (8.71%), panicle weight (7.81%) and plant height (7.36%). Hence, major emphasis could be given to these traits for a better selection of divergent genotypes.
Keywords	Cenchrus americanus ; genetic variation ; grain yield ; hybridization ; panicles ; plant height ; statistics
Language	English
Dates of publication	2021-12
Size	p. 1120-1126.
Publishing place	Indian Society of Plant Breeders
Document type	Article
ZDB-ID	2534084-0
ISSN	0975-928X
ISSN	0975-928X
DOI	10.37992/2021.1204.154
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Extracellular Enzymatic Activity of Candida Species Isolated from Patients with Head and Neck Cancer Undergoing Radiation Therapy and Its Correlation with Mucositis

Neethu Babu / Chitralekha Saikumar / Jomon Raphael Chalissery / Harish Kumar

Journal of Clinical and Diagnostic Research, Vol 17, Iss 09, Pp 01-

A Cross-Sectional Study

2023 Volume 05

Abstract: ... albicans and NAC species causing infections in men and women (p-value=0.390), as well ... as in those with diabetes (p-value=0.127) and hypertension ... ...

Abstract	Introduction: The differences in enzymatic activity expressed by various Candida species determine their virulence and play a pivotal role in understanding the pathogenesis of candidiasis. Additionally, this knowledge aids in the development of new antifungal drugs that target these enzymes, thereby enhancing therapeutic approaches. Understanding the extracellular enzymatic activity of Candida species is crucial for the development of new anticandidial drugs targeting these enzymes. Aim: To determine the differences in enzymatic activity expressed by various Candida species isolated from patients with Head and Neck Cancer (HNC) undergoing Radiation Therapy (RT) and to correlate these differences with the severity of mucositis. Materials and Methods: This cross-sectional study evaluated the enzymatic activity of Candida species, including C. albicans and Non albicans Candida species (NAC), isolated from HNC patients undergoing RT at the radiation oncology department, Amala Institute of Medical Sciences, Thrissur, Kerala, India. A total of 276 patients were enrolled in the study over a four-year period (January 2019 to December 2022). Extracellular enzymatic activities such as proteinase, phospholipase, haemolysin, and esterase were detected using the plate method, as described previously. Mucositis was graded according to the Radiation Therapy Oncology Group (RTOG) criteria. Data were analysed using Statistical Package for the Social Sciences (SPSS) version 23.0 (IBM, Illinois, US). The Chi-square test was used to analyse the variables, and the unpaired t-test was used to compare enzymatic activity. Spearman’s rank correlation was used to identify any correlation between mucositis and extracellular enzymatic activity. Results: A total of 97 Candida strains (56 C. albicans and 41 NAC) were isolated. There was no statistically significant difference between C. albicans and NAC species causing infections in men and women (p-value=0.390), as well as in those with diabetes (p-value=0.127) and hypertension ...
Keywords	candidiasis ; candida albicans ; drug resistance ; enzymes ; virulence ; Medicine ; R
Subject code	590
Language	English
Publishing date	2023-09-01T00:00:00Z
Publisher	JCDR Research and Publications Private Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: A Paraurethral Aggressive (Deep) Angiomyxoma.

York, Daniel / Saikumar, Smera / Patel, Pavan / Edwards, Christian / Garcia, Geossette / Naqvi, Hyder

Case reports in obstetrics and gynecology

2022 Volume 2022, Page(s) 5604460

Abstract: Background: Aggressive angiomyxomas (AAs) are rare mesenchymal tumors that are histologically composed of myxoid stroma and vasculature. AAs are typically located in the pelvis and perineum and occur more frequently in females of reproductive age. : ... ...

Abstract	Background: Aggressive angiomyxomas (AAs) are rare mesenchymal tumors that are histologically composed of myxoid stroma and vasculature. AAs are typically located in the pelvis and perineum and occur more frequently in females of reproductive age. Conclusion: Due to its rarity, aggressive angiomyxomas are often misdiagnosed as cysts, hernias, lipomas, or cancerous lesions. Although benign, close follow-ups are crucial to monitor for recurrences or metastasis.
Language	English
Publishing date	2022-07-20
Publishing country	United States
Document type	Case Reports
ZDB-ID	2627654-9
ISSN	2090-6692 ; 2090-6684
ISSN (online)	2090-6692
ISSN	2090-6684
DOI	10.1155/2022/5604460
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Article ; Online: Depression Screening Scores and Allergy and Gastrointestinal Medication Use in Adolescents.

Harris, Kari / Saikumar, Pavithra / Sunkoj, Yojana / Vancuren, Trista / Olufowote, Blessing / Dedeaux, Julian

Current drug safety

2022 Volume 18, Issue 3, Page(s) 335–339

Abstract: Introduction: Between 2005 and 2014, the 12-month prevalence of major depressive episodes among adolescents aged 12 to 17 years increased from 8.5% to 11.3%. Adolescent-onset depression is related to increased risk for depression and suicidal attempts ... ...

Abstract	Introduction: Between 2005 and 2014, the 12-month prevalence of major depressive episodes among adolescents aged 12 to 17 years increased from 8.5% to 11.3%. Adolescent-onset depression is related to increased risk for depression and suicidal attempts in adulthood. It is known that depression is an adverse effect among adults taking OAM; however, the effect of OAM on adolescents is unknown. Aim: The aim of this study was to describe the relationship between Patient Health Questionnaire 9- Modified (PHQ9-M) scores and OAM use among adolescents. Methods: This study included data abstracted from charts of adolescents aged 12 to 21 years who completed a Kansas Be Healthy wellness appointment at the KUSM-W Peds Clinic in 2017. Odds ratios were used to calculate the relationship between oral allergy medication and gastrointestinal medication use among adolescents and PHQ9-M scores. Results: Of the 425 adolescent charts analyzed, 22% (n=96) had positive PHQ9-M screens (a score of 10 or greater), and 13% (n=56) reported current use of allergy medication and/or GI medications. Adolescents taking oral allergy medication were 1.77 times more likely to have a positive PHQ9-M screen than those not taking oral allergy medication. Among adolescents on allergy medication, there was no difference in PHQ9- M scores based on the drug class (1<sup>st</sup> or 2<up>nd</sup> generation antihistamine or Montelukast). Conclusion: Healthcare providers must diligently explore OAM/GI use with adolescents during clinical encounters and discuss possible adverse effects of OAM on mood.
MeSH term(s)	Adult ; Humans ; Adolescent ; Depression ; Depressive Disorder, Major ; Hypersensitivity
Language	English
Publishing date	2022-08-31
Publishing country	United Arab Emirates
Document type	Journal Article
ZDB-ID	2250840-5
ISSN	2212-3911 ; 1574-8863
ISSN (online)	2212-3911
ISSN	1574-8863
DOI	10.2174/1574886317666220826170140
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