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  1. Book: A practical guide to human cancer genetics

    Hodgson, Shirley Victoria

    2014  

    Author's details Shirley Hodgson
    Keywords Neoplasms / genetics
    Language English
    Size XIX, 420 S. : Ill., graph. Darst.
    Edition 4. ed.
    Publisher Springer
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT018125078
    ISBN 978-1-4471-2374-3 ; 9781447123750 ; 1-4471-2374-3 ; 1447123751
    Database Catalogue ZB MED Medicine, Health

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  2. Book: A practical guide to human cancer genetics

    Hodgson, Shirley Victoria

    2007  

    Title variant Human cancer genetics
    Author's details Shirley Hodgson
    Keywords Neoplasms / genetics
    Language English
    Size IX, 395 S. : Ill., graph. Darst.
    Edition 3. ed.
    Publisher Cambridge Univ. Press
    Publishing place Cambridge u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT014837380
    ISBN 0-521-68563-X ; 978-0-521-68563-4
    Database Catalogue ZB MED Medicine, Health

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  3. Article: Understanding West Africa's Ebola epidemic.

    Hodgson, Shirley

    Medicine, conflict, and survival

    2017  Volume 33, Issue 4, Page(s) 320–323

    Language English
    Publishing date 2017-12-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 1314196-x
    ISSN 1362-3699
    ISSN 1362-3699
    DOI 10.1080/13623699.2017.1411562
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Moving health sovereignty in Africa - disease, governance, climate change.

    Hodgson, Shirley

    Medicine, conflict, and survival

    2015  Volume 31, Issue 2, Page(s) 134–136

    Language English
    Publishing date 2015-04-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 1314196-x
    ISSN 1362-3699
    ISSN 1362-3699
    DOI 10.1080/13623699.2015.1032523
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: A practical guide to human cancer genetics

    Hodgson, Shirley Victoria / Maher, Eamonn R.

    1999  

    Author's details Shirley V. Hodgson and Eamonn R. Maher
    Keywords Krebs ; Humangenetik
    Subject Medizinische Genetik ; Anthropogenetik ; Mensch ; Medizin ; Carcinom ; Malignom ; Maligner Tumor ; Neoplasma ; Karzinom ; Bösartiger Tumor ; Krebserkrankung
    Language English
    Size XVI, 336 S. : Ill., graph. Darst.
    Edition 2. ed.
    Publisher Cambridge Univ. Press
    Publishing place Cambridge u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT010907100
    ISBN 0-521-64961-7 ; 978-0-521-64961-2
    Database Catalogue ZB MED Medicine, Health

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  6. Book: A practical guide to human cancer genetics

    Hodgson, Shirley Victoria / Maher, Eamonn R.

    1993  

    Author's details S. V. Hodgson ; E. R. Maher
    Keywords Neoplasms / genetics ; Neoplastic Syndromes, Hereditary ; Krebs ; Erbkrankheit
    Subject Genetische Krankheit ; Heredopathie ; Genetisch bedingte Krankheit ; Genetisches Syndrom ; Erbkrankheiten ; Carcinom ; Malignom ; Maligner Tumor ; Neoplasma ; Karzinom ; Bösartiger Tumor ; Krebserkrankung
    Language English
    Size XVIII, 240 S. : Ill., graph. Darst.
    Publisher Cambridge Univ. Pr
    Publishing place Cambridge
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT004558982
    ISBN 0-521-40128-3 ; 0-521-40951-9 ; 978-0-521-40128-9 ; 978-0-521-40951-3
    Database Catalogue ZB MED Medicine, Health

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  7. Article: Advances in cancer genetics.

    Hodgson, Shirley

    Clinical medicine (London, England)

    2009  Volume 9, Issue 2, Page(s) 151–153

    MeSH term(s) Breast Neoplasms/genetics ; Colorectal Neoplasms, Hereditary Nonpolyposis/genetics ; Female ; Genetic Predisposition to Disease ; Genetics, Medical/trends ; Humans ; Neoplasms/drug therapy ; Neoplasms/epidemiology ; Neoplasms/genetics
    Language English
    Publishing date 2009-05-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2048646-7
    ISSN 1473-4893 ; 1470-2118
    ISSN (online) 1473-4893
    ISSN 1470-2118
    DOI 10.7861/clinmedicine.9-2-151
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Diagnosis and Management of Hereditary Thyroid Cancer.

    Bano, Gul / Hodgson, Shirley

    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer

    2016  Volume 205, Page(s) 29–44

    Abstract: Thyroid cancers are largely divided into medullary (MTC) and non-medullary (NMTC) cancers , depending on the cell type of origin. Familial non-medullary thyroid cancer (FNMTC) comprises about 5-15% of NMTC and is a heterogeneous group of diseases, ... ...

    Abstract Thyroid cancers are largely divided into medullary (MTC) and non-medullary (NMTC) cancers , depending on the cell type of origin. Familial non-medullary thyroid cancer (FNMTC) comprises about 5-15% of NMTC and is a heterogeneous group of diseases, including both non-syndromic and syndromic forms. Non-syndromic FNMTC tends to manifest papillary thyroid carcinoma , usually multifocal and bilateral . Several high-penetrance genes for FNMTC have been identified, but they are often confined to a few or single families, and other susceptibility loci appear to play a small part, conferring only small increments in risk. Familial susceptibility is likely to be due to a combination of genetic and environmental influences. The current focus of research in FNMTC is to characterise the susceptibility genes and their role in carcinogenesis. FNMTC can also occur as a part of multitumour genetic syndromes such as familial adenomatous polyposis , Cowden's disease , Werner's syndrome and Carney complex . These tend to present at an early age and are multicentric and bilateral with distinct pathology. The clinical evaluation of these patients is similar to that for most patients with a thyroid nodule. Medullary thyroid cancer (MTC) arises from the parafollicular cells of the thyroid which release calcitonin. The familial form of MTC accounts for 20-25% of cases and presents as a part of the multiple endocrine neoplasia type 2 (MEN 2) syndromes or as a pure familial MTC (FMTC). They are caused by germline point mutations in the RET oncogene on chromosome 10q11.2. There is a clear genotype-phenotype correlation, and the aggressiveness of FMTC depends on the specific genetic mutation, which should determine the timing of surgery.
    MeSH term(s) Genetic Predisposition to Disease ; Genetic Testing ; Genotype ; Humans ; Neoplastic Syndromes, Hereditary/diagnosis ; Neoplastic Syndromes, Hereditary/genetics ; Neoplastic Syndromes, Hereditary/therapy ; Phenotype ; Thyroid Neoplasms/diagnosis ; Thyroid Neoplasms/genetics ; Thyroid Neoplasms/therapy
    Language English
    Publishing date 2016
    Publishing country Germany
    Document type Journal Article
    ISSN 0080-0015
    ISSN 0080-0015
    DOI 10.1007/978-3-319-29998-3_3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Mechanisms of inherited cancer susceptibility.

    Hodgson, Shirley

    Journal of Zhejiang University. Science. B

    2008  Volume 9, Issue 1, Page(s) 1–4

    Abstract: A small proportion of many cancers are due to inherited mutations in genes, which result in a high risk to the individual of developing specific cancers. There are several classes of genes that may be involved: tumour suppressor genes, oncogenes, genes ... ...

    Abstract A small proportion of many cancers are due to inherited mutations in genes, which result in a high risk to the individual of developing specific cancers. There are several classes of genes that may be involved: tumour suppressor genes, oncogenes, genes encoding proteins involved in DNA repair and cell cycle control, and genes involved in stimulating the angiogenic pathway. Alterations in susceptibility to cancer may also be due to variations in genes involved in carcinogen metabolism. This review discusses examples of some of these genes and the associated clinical conditions caused by the inheritance of mutations in such genes.
    MeSH term(s) DNA Repair/genetics ; Genes, Tumor Suppressor ; Genetic Predisposition to Disease ; Humans ; Neoplasms/genetics ; Neovascularization, Physiologic/genetics ; Oncogenes
    Language English
    Publishing date 2008-01
    Publishing country China
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2247290-3
    ISSN 1862-1783 ; 1673-1581
    ISSN (online) 1862-1783
    ISSN 1673-1581
    DOI 10.1631/jzus.B073001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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