LIVIVO - Search results -

Search results

Result 1 - 10 of total 34

Search options

Article ; Online: Uterine Natural Killer Cell Heterogeneity: Lessons From Mouse Models.

Sojka, Dorothy K

2020 Volume 11, Page(s) 290

Abstract: Natural killer (NK) cells are the most abundant lymphocytes at the maternal-fetal interface. Epidemiological data implicate NK cells in human pregnancy outcomes. Discoveries using mouse NK cells have guided subsequent advances in human NK cell biology. ... ...

Abstract	Natural killer (NK) cells are the most abundant lymphocytes at the maternal-fetal interface. Epidemiological data implicate NK cells in human pregnancy outcomes. Discoveries using mouse NK cells have guided subsequent advances in human NK cell biology. However, it remains challenging to identify mouse and human uterine NK (uNK) cell function(s) because of the dynamic changes in the systemic-endocrinological and local uterine structural microenvironments during pregnancy. This review discusses functional similarities and differences between mouse and human NK cells at the maternal-fetal interface.
MeSH term(s)	Animals ; Female ; Killer Cells, Natural/immunology ; Maternal-Fetal Exchange ; Mice ; Models, Animal ; Pregnancy ; Uterus/immunology
Language	English
Publishing date	2020-02-21
Publishing country	Switzerland
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Review
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2020.00290
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Uterine Natural Killer Cells.

Sojka, Dorothy K / Yang, Liping / Yokoyama, Wayne M

Frontiers in immunology

2019 Volume 10, Page(s) 960

Abstract: Natural killer (NK) cells are members of a rapidly expanding family of innate lymphoid cells (ILCs). While most previously studied NK cells were derived from the mouse spleen and circulate in the blood, recently others and we found tissue-resident NK ( ... ...

Abstract	Natural killer (NK) cells are members of a rapidly expanding family of innate lymphoid cells (ILCs). While most previously studied NK cells were derived from the mouse spleen and circulate in the blood, recently others and we found tissue-resident NK (trNK) cells in many tissues that resemble group 1 ILCs (ILC1s). During pregnancy, NK cells are the most abundant lymphocytes in the uterus at the maternal-fetal interface and are involved in placental vascular remodeling. Prior studies suggested that these uterine NK (uNK) cells are mostly derived from circulating NK cells. However, the murine virgin uterus contains mostly trNK cells and it has been challenging to determine their contribution to uNK cells in pregnancy as well as other potential function(s) of uNK cells due to the dynamic microenvironment in the pregnant uterus. This review focuses on the origins and functions of the heterogeneous populations of uNK cells during the course of murine pregnancy.
MeSH term(s)	Animals ; Female ; Humans ; Killer Cells, Natural/immunology ; Mice ; Uterus/cytology ; Uterus/immunology
Language	English
Publishing date	2019-05-01
Publishing country	Switzerland
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Review
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2019.00960
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Uterine natural killer cells: To protect and to nurture.

Sojka, Dorothy K / Yang, Liping / Yokoyama, Wayne M

Birth defects research

2018 Volume 110, Issue 20, Page(s) 1531–1538

Abstract: During the course of pregnancy, the maternal-fetal interface is tightly regulated and undergoes dynamic changes that promote the successful development of the semi-allogeneic fetus. In response to embryo implantation, the uterus remodels with maternal ... ...

Abstract	During the course of pregnancy, the maternal-fetal interface is tightly regulated and undergoes dynamic changes that promote the successful development of the semi-allogeneic fetus. In response to embryo implantation, the uterus remodels with maternal immune cells occupying the maternal-fetal interface and uterine natural killer (uNK) cells becoming the most prominent leukocyte. Recently, uNK cells have been discovered to be heterogeneous, including conventional NK and tissue-resident NK cells. Here, we will review the recent advances in uNK cell biology and discuss their functional mechanisms which protect and nurture the growing fetus.
MeSH term(s)	Animals ; Female ; Fetal Development/immunology ; Fetus/immunology ; Humans ; Killer Cells, Natural/physiology ; Maternal-Fetal Exchange/physiology ; Pregnancy/immunology ; Uterus/immunology
Language	English
Publishing date	2018-11-22
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Review
ZDB-ID	2104792-3
ISSN	2472-1727
ISSN (online)	2472-1727
DOI	10.1002/bdr2.1419
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 749: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Tissue-resident natural killer cells and their potential diversity.

Sojka, Dorothy K / Tian, Zhigang / Yokoyama, Wayne M

Seminars in immunology

2014 Volume 26, Issue 2, Page(s) 127–131

Abstract: Conventional NK cells are well characterized in the mouse spleen and circulate in the blood. Less well described are NK cells found in organs such as the liver, thymus, and uterus. Recently we identified a tissue-resident NK (trNK) cell population in the ...

Abstract	Conventional NK cells are well characterized in the mouse spleen and circulate in the blood. Less well described are NK cells found in organs such as the liver, thymus, and uterus. Recently we identified a tissue-resident NK (trNK) cell population in the liver, suggesting a potential diversity of trNK cells in other organs. In this review we compare and contrast the similarities and differences among the subpopulations of NK and innate lymphoid cells to the trNK cells in the liver.
MeSH term(s)	Animals ; Humans ; Killer Cells, Natural/cytology ; Killer Cells, Natural/immunology ; Killer Cells, Natural/metabolism ; Lymphocyte Subsets/cytology ; Lymphocyte Subsets/immunology ; Lymphocyte Subsets/metabolism ; Lymphoid Tissue/cytology ; Lymphoid Tissue/immunology ; Phenotype
Language	English
Publishing date	2014-02-16
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	1018141-6
ISSN	1096-3618 ; 1044-5323
ISSN (online)	1096-3618
ISSN	1044-5323
DOI	10.1016/j.smim.2014.01.010
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2843: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Regulatory T cells inhibit acute IFN-γ synthesis without blocking T-helper cell type 1 (Th1) differentiation via a compartmentalized requirement for IL-10.

Sojka, Dorothy K / Fowell, Deborah J

Proceedings of the National Academy of Sciences of the United States of America

2011 Volume 108, Issue 45, Page(s) 18336–18341

Abstract: CD4(+)CD25(+)Forkhead box P3 (Foxp3)(+) regulatory T cells (Tregs) control immune responses to self and foreign antigens in secondary lymphoid organs and at tissue sites of inflammation. Tregs can modify the function of many immune cells and have been ... ...

Abstract	CD4(+)CD25(+)Forkhead box P3 (Foxp3)(+) regulatory T cells (Tregs) control immune responses to self and foreign antigens in secondary lymphoid organs and at tissue sites of inflammation. Tregs can modify the function of many immune cells and have been proposed to block early proliferation, differentiation, and effector function. Acute ablation of Tregs has revealed rapid cytokine production immediately after Treg removal, suggesting that Tregs may regulate effector function acutely rather than regulating the programming for immune function. We developed in vitro and in vivo models that enabled the direct test of Treg regulation of T-helper cell type 1 (Th1) differentiation. CD28 signaling is known to abrogate Treg suppression of IL-2 secretion and proliferation, but our studies show that Treg suppression of IFN-γ during Th1 priming proceeds despite enhanced CD28 signaling. Importantly, during Th1 differentiation, Tregs inhibited early IFN-γ transcription without disrupting expression of Th1-specific T-box transcription factor (Tbet) and Th1 programming. Acute shutoff of effector cytokine production by Tregs was selective for IFN-γ but not TNF-α and was independent of TGF-β and Epstein-Barr virus-induced gene 3. In vivo, Tregs potently controlled CD4 IFN-γ and CD4 effector cell expansion in the lymph node (four- to fivefold reduction) but not Th1 programming, independent of IL-10. Tregs additionally reduced CD4 IFN-γ in the inflamed dermis (twofold reduction) dependent on their production of IL-10. We propose a model for Treg inhibition of effector function based on acute cytokine regulation. Interestingly, Tregs used different regulatory mechanisms to regulate IFN-γ (IL-10-dependent or -independent) subject to the target T-cell stage of activation and its tissue location.
MeSH term(s)	Animals ; Cell Compartmentation ; Cell Differentiation ; Cell Lineage ; Flow Cytometry ; Interferon-gamma/biosynthesis ; Interleukin-10/physiology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; T-Lymphocytes, Helper-Inducer/cytology ; T-Lymphocytes, Regulatory/immunology
Chemical Substances	Interleukin-10 (130068-27-8) ; Interferon-gamma (82115-62-6)
Language	English
Publishing date	2011-10-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	209104-5
ISSN	1091-6490 ; 0027-8424
ISSN (online)	1091-6490
ISSN	0027-8424
DOI	10.1073/pnas.1110566108
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1148: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Gardnerella vaginalis and Prevotella bivia Trigger Distinct and Overlapping Phenotypes in a Mouse Model of Bacterial Vaginosis.

Gilbert, Nicole M / Lewis, Warren G / Li, Guocai / Sojka, Dorothy K / Lubin, Jean Bernard / Lewis, Amanda L

The Journal of infectious diseases

2019 Volume 220, Issue 7, Page(s) 1099–1108

Abstract: Background: Bacterial vaginosis (BV) is a common imbalance of the vaginal microbiota characterized by overgrowth of diverse Actinobacteria, Firmicutes, and Gram-negative anaerobes. Women with BV are at increased risk of secondary reproductive tract ... ...

Abstract	Background: Bacterial vaginosis (BV) is a common imbalance of the vaginal microbiota characterized by overgrowth of diverse Actinobacteria, Firmicutes, and Gram-negative anaerobes. Women with BV are at increased risk of secondary reproductive tract infections and adverse pregnancy outcomes. However, which specific bacteria cause clinical features of BV is unclear. Methods: We previously demonstrated that Gardnerella vaginalis could elicit many BV features in mice. In this study, we established a BV model in which we coinfected mice with G. vaginalis and another species commonly found in women with BV: Prevotella bivia. Results: This coinfection model recapitulates several aspects of human BV, including vaginal sialidase activity (a diagnostic BV feature independently associated with adverse outcomes), epithelial exfoliation, and ascending infection. It is notable that G. vaginalis facilitated uterine infection by P. bivia. Conclusions: Taken together, our model provides a framework for advancing our understanding of the role of individual or combinations of BV-associated bacteria in BV pathogenesis.
MeSH term(s)	Animals ; Coinfection/microbiology ; Disease Models, Animal ; Female ; Gardnerella vaginalis/genetics ; Humans ; Mice ; Mice, Inbred C57BL ; Microbiota ; Neuraminidase/analysis ; Phenotype ; Prevotella/genetics ; RNA, Bacterial/genetics ; RNA, Ribosomal, 16S/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Vagina/microbiology ; Vaginosis, Bacterial/microbiology
Chemical Substances	RNA, Bacterial ; RNA, Ribosomal, 16S ; Neuraminidase (EC 3.2.1.18)
Language	English
Publishing date	2019-02-21
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	3019-3
ISSN	1537-6613 ; 0022-1899
ISSN (online)	1537-6613
ISSN	0022-1899
DOI	10.1093/infdis/jiy704
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uh II Zs.50: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 445: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Cutting Edge: Local Proliferation of Uterine Tissue-Resident NK Cells during Decidualization in Mice.

Sojka, Dorothy K / Yang, Liping / Plougastel-Douglas, Beatrice / Higuchi, Darryl A / Croy, B Anne / Yokoyama, Wayne M

Journal of immunology (Baltimore, Md. : 1950)

2018 Volume 201, Issue 9, Page(s) 2551–2556

Abstract: NK cells accumulate in adult murine and human uteri during decidualization induced physiologically, pathologically, or experimentally. Adoptive transfer studies indicate that uterine NK (uNK) cells arise from circulating progenitors. However, virgin ... ...

Abstract	NK cells accumulate in adult murine and human uteri during decidualization induced physiologically, pathologically, or experimentally. Adoptive transfer studies indicate that uterine NK (uNK) cells arise from circulating progenitors. However, virgin uteri contain few circulating NK1.1
MeSH term(s)	Animals ; Antigens, Ly/genetics ; Antigens, Ly/metabolism ; Cell Movement/immunology ; Cell Proliferation/physiology ; Decidua/cytology ; Decidua/immunology ; Female ; Green Fluorescent Proteins/genetics ; Killer Cells, Natural/cytology ; Killer Cells, Natural/immunology ; Mice ; Mice, Inbred C57BL ; Natural Cytotoxicity Triggering Receptor 1/genetics ; Natural Cytotoxicity Triggering Receptor 1/metabolism ; Parabiosis ; Pregnancy ; Pregnancy, Animal
Chemical Substances	Antigens, Ly ; Natural Cytotoxicity Triggering Receptor 1 ; Ncr1 protein, mouse ; Green Fluorescent Proteins (147336-22-9)
Language	English
Publishing date	2018-10-01
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	3056-9
ISSN	1550-6606 ; 0022-1767 ; 1048-3233 ; 1047-7381
ISSN (online)	1550-6606
ISSN	0022-1767 ; 1048-3233 ; 1047-7381
DOI	10.4049/jimmunol.1800651
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ud II Zs.37: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MG 28: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: T cell response kinetics determines neuroinfection outcomes during murine HSV infection.

Lee, Aisha G / Scott, Jason M / Fabbrizi, Maria Rita / Jiang, Xiaoping / Sojka, Dorothy K / Miller, Mark J / Baldridge, Megan T / Yokoyama, Wayne M / Shin, Haina

JCI insight

2020 Volume 5, Issue 5

Abstract: Herpes simplex virus-2 (HSV-2) and HSV-1 both can cause genital herpes, a chronic infection that establishes a latent reservoir in the nervous system. Clinically, the recurrence frequency of HSV-1 genital herpes is considerably less than HSV-2 genital ... ...

Abstract	Herpes simplex virus-2 (HSV-2) and HSV-1 both can cause genital herpes, a chronic infection that establishes a latent reservoir in the nervous system. Clinically, the recurrence frequency of HSV-1 genital herpes is considerably less than HSV-2 genital herpes, which correlates with reduced neuronal infection. The factors dictating the disparate outcomes of HSV-1 and HSV-2 genital herpes are unclear. In this study, we show that vaginal infection of mice with HSV-1 leads to the rapid appearance of mature DCs in the draining lymph node, which is dependent on an early burst of NK cell-mediated IFN-γ production in the vagina that occurs after HSV-1 infection but not HSV-2 infection. Rapid DC maturation after HSV-1 infection, but not HSV-2 infection, correlates with the accelerated generation of a neuroprotective T cell response and early accumulation of IFN-γ-producing T cells at the site of infection. Depletion of T cells or loss of IFN-γ receptor (IFN-γR) expression in sensory neurons both lead to a marked loss of neuroprotection only during HSV-1, recapitulating a prominent feature of HSV-2 infection. Our experiments reveal key differences in host control of neuronal HSV-1 and HSV-2 infection after genital exposure of mice, and they define parameters of a successful immune response against genital herpes.
MeSH term(s)	Animals ; Cell Differentiation ; Female ; Herpes Simplex/immunology ; Herpes Simplex/metabolism ; Herpes Simplex/virology ; Herpesvirus 1, Human/pathogenicity ; Herpesvirus 2, Human/pathogenicity ; Host-Pathogen Interactions ; Interferon-gamma/biosynthesis ; Mice ; Mice, Inbred C57BL ; Nervous System Diseases/immunology ; Nervous System Diseases/virology ; T-Lymphocytes/immunology
Chemical Substances	Interferon-gamma (82115-62-6)
Language	English
Publishing date	2020-03-12
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ISSN	2379-3708
ISSN (online)	2379-3708
DOI	10.1172/jci.insight.134258
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Cutting edge: Regulatory T cells selectively attenuate, not terminate, T cell signaling by disrupting NF-κB nuclear accumulation in CD4 T cells.

Huang, Yu-Hui / Sojka, Dorothy K / Fowell, Deborah J

Journal of immunology (Baltimore, Md. : 1950)

2012 Volume 188, Issue 3, Page(s) 947–951

Abstract: A key consequence of regulatory T cell (Treg) suppression of CD4 T cells is the inhibition of IL-2 production, yet how Tregs attenuate IL-2 has not been defined. Current models predict a termination of TCR signaling, by disrupting T-APC contacts, or TCR ... ...

Abstract	A key consequence of regulatory T cell (Treg) suppression of CD4 T cells is the inhibition of IL-2 production, yet how Tregs attenuate IL-2 has not been defined. Current models predict a termination of TCR signaling, by disrupting T-APC contacts, or TCR signal modification, through mechanisms such as cAMP. To directly define Treg effects on TCR signaling in CD4 T cell targets, we visualized changes in nuclear accumulation of transcription factors at time points when IL-2 was actively suppressed. Nuclear accumulation of NFAT was highly dependent on sustained TCR signaling in the targets. However, in the presence of Tregs, NFAT and AP-1 signals were sustained in the target cells. In contrast, NF-κB p65 was selectively attenuated. Thus, Tregs do not generally terminate TCR signals. Rather, Tregs selectively modulate TCR signals within hours of contact with CD4 targets, independent of APCs, resulting in the specific loss of NF-κB p65 signals.
MeSH term(s)	Animals ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; Cell Nucleus/metabolism ; Interleukin-2/biosynthesis ; Mice ; NFATC Transcription Factors/metabolism ; Signal Transduction/immunology ; T-Lymphocytes/metabolism ; T-Lymphocytes, Regulatory/immunology ; Transcription Factor AP-1/metabolism ; Transcription Factor RelA/metabolism ; Transcription Factors/metabolism
Chemical Substances	Interleukin-2 ; NFATC Transcription Factors ; Rela protein, mouse ; Transcription Factor AP-1 ; Transcription Factor RelA ; Transcription Factors
Language	English
Publishing date	2012-01-06
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	3056-9
ISSN	1550-6606 ; 0022-1767 ; 1048-3233 ; 1047-7381
ISSN (online)	1550-6606
ISSN	0022-1767 ; 1048-3233 ; 1047-7381
DOI	10.4049/jimmunol.1101027
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ud II Zs.37: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MG 28: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Tissue-resident natural killer cells.

Yokoyama, Wayne M / Sojka, Dorothy K / Peng, Hui / Tian, Zhigang

Cold Spring Harbor symposia on quantitative biology

2013 Volume 78, Page(s) 149–156

Abstract: Natural killer (NK) cells kill infected and tumor cells and produce cytokines that modulate other immune cells. However, most of our current knowledge is derived from investigations of mouse splenic and human peripheral blood NK cells, "conventional" NK ... ...

Abstract	Natural killer (NK) cells kill infected and tumor cells and produce cytokines that modulate other immune cells. However, most of our current knowledge is derived from investigations of mouse splenic and human peripheral blood NK cells, "conventional" NK cells. Herein we discuss recent studies indicating that the liver contains two subpopulations of NK cells, one of which is liver-resident and bears distinct markers from another liver subpopulation that resembles conventional NK cells. Thus, the liver and potentially other organs contain tissue-resident NK cells that may differ from conventional NK cells in terms of origin, development, and/or function.
MeSH term(s)	Animals ; Cell Separation ; Female ; Flow Cytometry ; Humans ; Inflammation ; Killer Cells, Natural/cytology ; Leukocytes, Mononuclear/cytology ; Liver/cytology ; Lymph Nodes/cytology ; Mice ; Mice, Inbred C57BL ; Spleen/cytology ; Thymus Gland/cytology ; Uterus/cytology
Language	English
Publishing date	2013
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ISSN	1943-4456 ; 0091-7451
ISSN (online)	1943-4456
ISSN	0091-7451
DOI	10.1101/sqb.2013.78.020354
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Order via subito