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  1. Book ; Online ; E-Book: Nanotherapeutics in cancer

    Singh Tuli, Hardeep

    materials, diagnostics, and clinical applications

    2023  

    Abstract: This book provides complete information about each aspect of nanomaterials and nanotherapeutics, including synthesis, analysis, disease diagnosis, mechanistic insight, targetted drug delivery, and clinical implications in a concise and informative way. ...

    Author's details edited by Hardeep Singh Tuli
    Abstract This book provides complete information about each aspect of nanomaterials and nanotherapeutics, including synthesis, analysis, disease diagnosis, mechanistic insight, targetted drug delivery, and clinical implications in a concise and informative way.
    Keywords Cancer/Diagnosis ; Cancer/Treatment ; Nanomedicine.
    Subject code 616.994075
    Language English
    Size 1 online resource (279 pages)
    Publisher Jenny Stanford Publishing
    Publishing place Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-00-333453-9 ; 1-000-77662-X ; 1-003-33453-9 ; 981-4968-41-2 ; 978-1-00-333453-8 ; 978-1-000-77662-1 ; 978-1-003-33453-8 ; 978-981-4968-41-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online ; E-Book: Current aspects of flavonoids

    Singh Tuli, Hardeep

    their role in cancer treatment

    2019  

    Author's details Hardeep Singh Tuli editor
    Keywords Oncology ; Toxicology ; Bioorganic chemistry ; Nanotechnology
    Language English
    Size 1 Online-Ressource (xviii, 181 Seiten), Illustrationen, Diagramme
    Publisher Springer
    Publishing place Singapore
    Publishing country Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020082866
    ISBN 978-981-135-874-6 ; 9789811358739 ; 981-135-874-5 ; 9811358737
    DOI 10.1007/978-981-13-5874-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online ; E-Book: Drug targets in cellular processes of cancer

    Tuli, Hardeep Singh

    from nonclinical to preclinical models

    2020  

    Abstract: This book explores potential cellular drug targets for cancer therapy. The first couple of chapters describe conventional treatment (radiotherapy, chemotherapy, and immunotherapy) & detection (biosensors) strategies for cancer. In contrast, the ... ...

    Author's details Hardeep Singh Tuli, editor
    Abstract This book explores potential cellular drug targets for cancer therapy. The first couple of chapters describe conventional treatment (radiotherapy, chemotherapy, and immunotherapy) & detection (biosensors) strategies for cancer. In contrast, the subsequent chapters address the role of cyclin-dependent kinases and cell cycle regulatory proteins in the growth of cancer cells and their potential as target for cancer treatment. The book then discusses the regulation of various pro-apoptotic and anti-apoptotic proteins via chemotherapeutic drugs. In addition, it examines the molecular mechanisms that are critical for mediating autophagic cell death in cancer cells. It subsequently reviews the role of reactive oxygen (ROS) species during carcinogenesis and during chemotherapy, and the potential of anti-inflammatory routes for the development of new therapeutic modulators. Lastly, it describes therapeutic strategies that target the tumor microenvironment and various angiogenic pathways for the treatment of cancer and to develop personalized medicine. Given its scope, the book is valuable resource for oncologists, cancer researchers, clinicians, and pharmaceutical industry personnel.
    Keywords Cancer/Molecular aspects
    Subject code 616.994
    Language English
    Size 1 online resource (XIII, 228 p. 28 illus., 26 illus. in color.)
    Edition 1st ed. 2020.
    Publisher Springer
    Publishing place Gateway East, Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 981-15-7586-X ; 981-15-7585-1 ; 978-981-15-7586-0 ; 978-981-15-7585-3
    DOI 10.1007/978-981-15-7586-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article: Editorial: Phytochemical-based nanoformulations to tackle drug resistance in cancer.

    Tuli, Hardeep Singh / Kaur, Ginpreet / Yerer, Mükerrem Betül

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1165596

    Language English
    Publishing date 2023-03-16
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1165596
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Editorial: COVID 19: New Variants and Host Demography.

    Kaur, Ginpreet / Tuli, Hardeep Singh

    Frontiers in cellular and infection microbiology

    2022  Volume 12, Page(s) 905817

    MeSH term(s) COVID-19 ; Demography ; Humans ; SARS-CoV-2/genetics ; Vaccination
    Language English
    Publishing date 2022-05-02
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2022.905817
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Cancer and Nutrients.

    Tuli, Hardeep Singh / Yerer, Mukerrem Betul / Yadav, Vikas

    Cancers

    2023  Volume 15, Issue 16

    Abstract: Editorial: Over the last few decades, the scientific community has recognized the enormous potential of bioactive dietary nutrients/components in the management and prevention of cancer [ ... ]. ...

    Abstract Editorial: Over the last few decades, the scientific community has recognized the enormous potential of bioactive dietary nutrients/components in the management and prevention of cancer [...].
    Language English
    Publishing date 2023-08-17
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15164151
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Editorial: Current Aspects in Chemopreventive Strategies, Volume II.

    Tuli, Hardeep Singh / Yerer, Mükerrem Betül / Sak, Katrin

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 961334

    Language English
    Publishing date 2022-07-15
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.961334
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Patent landscape highlighting double-edged scaffold of a WNT5A-agonizing peptide, Foxy5.

    Yadav, Vikas / Islam, Rubina / Tuli, Hardeep Singh

    Pharmaceutical patent analyst

    2023  Volume 12, Issue 2, Page(s) 69–77

    Abstract: Aberrant expression of the WNT signaling pathway has been associated with cancer progression and recurrence. Research over the decades has led to development of WNT-targetable small molecules, but has faced challenges in translating to clinics. Unlike ... ...

    Abstract Aberrant expression of the WNT signaling pathway has been associated with cancer progression and recurrence. Research over the decades has led to development of WNT-targetable small molecules, but has faced challenges in translating to clinics. Unlike WNT/β-catenin inhibitors, WNT5A-mimicking peptide, Foxy5 has shown encouraging efficacy in impairing metastasis of cancers with low or absent WNT5A expression. Recent patent application US20210008149 advocates the implication of Foxy5 for treatment and prevention of cancer relapse. The inventors have demonstrated the anti-stemness activity of Foxy5 in mice xenograft model via suppressing the expression of colonic cancer stem cell markers. Foxy5 also exhibits non-toxic nature when administered alone or in synergy with standard chemotherapy thus strengthening its candidature in the field of cancer therapeutics.
    MeSH term(s) Animals ; Humans ; Mice ; Neoplasm Recurrence, Local ; Peptides ; Wnt Signaling Pathway ; Wnt-5a Protein/genetics
    Chemical Substances Peptides ; Wnt-5a Protein ; WNT5A protein, human ; Foxy-5 peptide
    Language English
    Publishing date 2023-04-20
    Publishing country England
    Document type Journal Article
    ISSN 2046-8962
    ISSN (online) 2046-8962
    DOI 10.4155/ppa-2022-0037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Exosomal miRNAs as novel avenues for breast cancer treatment.

    Singh, Tejveer / Kaushik, Mahesh / Mishra, Lokesh Chandra / Behl, Chesta / Singh, Vijay / Tuli, Hardeep Singh

    Frontiers in genetics

    2023  Volume 14, Page(s) 1134779

    Abstract: Breast cancer is the most commonly diagnosed cancer and a leading cause of death in women worldwide. It is a heterogeneous disease, as shown by the gene expression profiles of breast cancer samples. It begins in milk-producing ducts, with a high degree ... ...

    Abstract Breast cancer is the most commonly diagnosed cancer and a leading cause of death in women worldwide. It is a heterogeneous disease, as shown by the gene expression profiles of breast cancer samples. It begins in milk-producing ducts, with a high degree of diversity between and within tumors, as well as among cancer-bearing individuals. The enhanced prevalence of breast cancer is influenced by various hormonal, lifestyle, and environmental factors, and very early onset of the disease correlates strongly with the risk of local and distant recurrence. Many subtypes are difficult to treat with conventional therapeutic modalities, and therefore, optimal management and early diagnosis are the first steps to minimizing the mortality linked with breast cancer. The use of newer methods of nanotechnology extends beyond the concept of synthesizing drug delivery mechanisms into the creation of new therapeutics, such as delivering chemotherapeutics with nanomaterial properties. Exosomes, a class of nanovesicles, are emerging as novel tools for deciphering the patient-specific proteins and biomarkers across different disease models, including breast cancer. In this review, we address the role of exosomal miRNA in breast cancer diagnosis and treatment.
    Language English
    Publishing date 2023-03-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2023.1134779
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Editorial: Current Aspects in Chemopreventive Strategies.

    Tuli, Hardeep Singh / Yerer, Mukerrem Betul / Sak, Katrin

    Frontiers in pharmacology

    2021  Volume 11, Page(s) 607503

    Language English
    Publishing date 2021-01-04
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2020.607503
    Database MEDical Literature Analysis and Retrieval System OnLINE

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