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  1. Article: Mediastinal Epidermoid Cyst in a 5-Year-Old Girl.

    Sloan, Keren A / Lakhoo, Kokila

    European journal of pediatric surgery reports

    2018  Volume 6, Issue 1, Page(s) e24–e26

    Abstract: A 5-year-old girl was referred to our unit with an incidental finding of a lesion on the right hemithorax situated within the right atrial shadow. Computed tomography thorax showed a well-defined soft tissue lesion felt to be consistent with a ... ...

    Abstract A 5-year-old girl was referred to our unit with an incidental finding of a lesion on the right hemithorax situated within the right atrial shadow. Computed tomography thorax showed a well-defined soft tissue lesion felt to be consistent with a bronchogenic cyst. The lesion was located in the posterior mediastinum, adherent to the diaphragm and inferior vena cava, but did not extend within the wall of the esophagus. It was entirely excised via video-assisted thoracoscopy converted to open thoracotomy. Histopathology confirmed an encapsulated nodular tissue measuring 2.5 × 2.5 × 2 cm lined by squamous type epithelium. Chronic inflammatory cells and foreign body giant cell reaction were found in the cyst wall. The appearances were that of a benign epidermoid cyst.
    Language English
    Publishing date 2018-03-22
    Publishing country Germany
    Document type Case Reports
    ZDB-ID 2674016-3
    ISSN 2194-7627 ; 2194-7619
    ISSN (online) 2194-7627
    ISSN 2194-7619
    DOI 10.1055/s-0037-1621707
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6998: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Mediastinal Epidermoid Cyst in a 5-Year-Old Girl

    Sloan, Keren A. / Lakhoo, Kokila

    European Journal of Pediatric Surgery Reports

    2018  Volume 06, Issue 01, Page(s) e24–e26

    Abstract: A 5-year-old girl was referred to our unit with an incidental finding of a lesion on the right hemithorax situated within the right atrial shadow. Computed tomography thorax showed a well-defined soft tissue lesion felt to be consistent with a ... ...

    Abstract A 5-year-old girl was referred to our unit with an incidental finding of a lesion on the right hemithorax situated within the right atrial shadow. Computed tomography thorax showed a well-defined soft tissue lesion felt to be consistent with a bronchogenic cyst. The lesion was located in the posterior mediastinum, adherent to the diaphragm and inferior vena cava, but did not extend within the wall of the esophagus. It was entirely excised via video-assisted thoracoscopy converted to open thoracotomy. Histopathology confirmed an encapsulated nodular tissue measuring 2.5 × 2.5 × 2 cm lined by squamous type epithelium. Chronic inflammatory cells and foreign body giant cell reaction were found in the cyst wall. The appearances were that of a benign epidermoid cyst.
    Keywords epidermoid cyst ; pediatric ; mediastinum
    Language English
    Publishing date 2018-01-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2674016-3
    ISSN 2194-7627 ; 2194-7619
    ISSN (online) 2194-7627
    ISSN 2194-7619
    DOI 10.1055/s-0037-1621707
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6998: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Outcomes of Esophageal Replacement: Gastric Pull-Up and Colonic Interposition Procedures.

    Bradshaw, Catherine Jane / Sloan, Keren / Morandi, Anna / Lakshminarayanan, Bhanumathi / Cox, Sharon Gail / Millar, Alastair J W / Numanoglu, Alp / Lakhoo, Kokila

    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie

    2018  Volume 28, Issue 1, Page(s) 22–29

    Abstract: Aim:  No consensus exists about the optimal surgical technique for esophageal replacement. This study reports the surgical outcomes for the gastric pull-up and the colonic interposition procedures.: Materials and methods:  A retrospective review of ... ...

    Abstract Aim:  No consensus exists about the optimal surgical technique for esophageal replacement. This study reports the surgical outcomes for the gastric pull-up and the colonic interposition procedures.
    Materials and methods:  A retrospective review of children undergoing esophageal replacement surgery between January 2001 and June 2015 across four different pediatric surgery centers was conducted. Data collected included indications, epidemiology, surgical technique, complications, and outcomes. Patients were divided into group A, those that had a gastric pull-up procedure and group B, those that had a colonic interposition procedure.
    Results:  In total, 50 patients were included; 29 in group A and 21 in group B. Indications included esophageal atresia, caustic ingestion, and infective esophageal stricture. The median age at the time of surgery was 13 months. The mean length of follow-up was 5.2 years. Three patients died giving a mortality rate of 6%; 2 in group A and 1 in group B.In both groups, early postoperative complications included infective complications, such as wound infections, sepsis, and pneumonia (11), anastomotic leak (7), and respiratory complications (7). Late complications included adhesive bowel obstruction (2), anastomotic strictures (4), redundancy (1), and jejunostomy problems (1). Septic complications and anastomotic strictures occurred more frequently in group B. Further surgery was needed in eight patients; this was significantly higher in group B. Full oral feeding was achieved within 6 months in 91.5%.
    Conclusion:  The gastric pull-up and colonic interposition have comparable mortality and outcomes. The colonic interposition was associated with a higher rate of early septic complications, anastomotic strictures, and need for further surgery.
    MeSH term(s) Child ; Child, Preschool ; Colon/transplantation ; Esophageal Atresia/mortality ; Esophageal Atresia/surgery ; Esophageal Stenosis/mortality ; Esophageal Stenosis/surgery ; Esophagoplasty/methods ; Female ; Follow-Up Studies ; Humans ; Infant ; Male ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Retrospective Studies ; Stomach/surgery ; Treatment Outcome
    Language English
    Publishing date 2018-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1065043-x
    ISSN 1439-359X ; 0939-7248 ; 0939-6764 ; 0930-7249
    ISSN (online) 1439-359X
    ISSN 0939-7248 ; 0939-6764 ; 0930-7249
    DOI 10.1055/s-0037-1607041
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3140: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Outcomes of Esophageal Replacement: Gastric Pull-Up and Colonic Interposition Procedures

    Bradshaw, Catherine Jane / Sloan, Keren / Morandi, Anna / Lakshminarayanan, Bhanumathi / Cox, Sharon Gail / Millar, Alastair J. W. / Numanoglu, Alp / Lakhoo, Kokila

    European Journal of Pediatric Surgery

    2017  Volume 28, Issue 01, Page(s) 22–29

    Abstract: Aim: No consensus exists about the optimal surgical technique for esophageal replacement. This study reports the surgical outcomes for the gastric pull-up and the colonic interposition procedures.: Materials and Methods: A retrospective review of ... ...

    Abstract Aim: No consensus exists about the optimal surgical technique for esophageal replacement. This study reports the surgical outcomes for the gastric pull-up and the colonic interposition procedures.
    Materials and Methods: A retrospective review of children undergoing esophageal replacement surgery between January 2001 and June 2015 across four different pediatric surgery centers was conducted. Data collected included indications, epidemiology, surgical technique, complications, and outcomes. Patients were divided into group A, those that had a gastric pull-up procedure and group B, those that had a colonic interposition procedure.
    Results: In total, 50 patients were included; 29 in group A and 21 in group B. Indications included esophageal atresia, caustic ingestion, and infective esophageal stricture. The median age at the time of surgery was 13 months. The mean length of follow-up was 5.2 years. Three patients died giving a mortality rate of 6%; 2 in group A and 1 in group B. In both groups, early postoperative complications included infective complications, such as wound infections, sepsis, and pneumonia (11), anastomotic leak (7), and respiratory complications (7). Late complications included adhesive bowel obstruction (2), anastomotic strictures (4), redundancy (1), and jejunostomy problems (1). Septic complications and anastomotic strictures occurred more frequently in group B. Further surgery was needed in eight patients; this was significantly higher in group B. Full oral feeding was achieved within 6 months in 91.5%.
    Conclusion: The gastric pull-up and colonic interposition have comparable mortality and outcomes. The colonic interposition was associated with a higher rate of early septic complications, anastomotic strictures, and need for further surgery.
    Keywords colonic interposition ; gastric pull-up ; esophageal replacement ; esophageal atresia ; caustic ingestion injury
    Language English
    Publishing date 2017-09-25
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 1065043-x
    ISSN 1439-359X ; 0939-7248 ; 0939-6764 ; 0930-7249
    ISSN (online) 1439-359X
    ISSN 0939-7248 ; 0939-6764 ; 0930-7249
    DOI 10.1055/s-0037-1607041
    Database Thieme publisher's database

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3140: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Evaluating the efficacy of vaginal dehydroepiandosterone for vaginal symptoms in postmenopausal cancer survivors: NCCTG N10C1 (Alliance).

    Barton, Debra L / Sloan, Jeff A / Shuster, Lynne T / Gill, Paula / Griffin, Patricia / Flynn, Kathleen / Terstriep, Shelby A / Rana, Fauzia N / Dockter, Travis / Atherton, Pamela J / Tsai, Michaela / Sturtz, Keren / Lafky, Jacqueline M / Riepl, Mike / Thielen, Jacqueline / Loprinzi, Charles L

    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

    2017  Volume 26, Issue 2, Page(s) 643–650

    Abstract: Background: Women with estrogen deficiencies can suffer from vaginal symptoms that negatively impact sexual health. This study evaluated vaginal dehydroepiandrosterone (DHEA) for alleviation of vaginal symptoms.: Methods: This three-arm randomized, ... ...

    Abstract Background: Women with estrogen deficiencies can suffer from vaginal symptoms that negatively impact sexual health. This study evaluated vaginal dehydroepiandrosterone (DHEA) for alleviation of vaginal symptoms.
    Methods: This three-arm randomized, controlled trial evaluated DHEA 3.25 mg and DHEA 6.5 mg, each compared to a plain moisturizer (PM) over 12 weeks, to improve the severity of vaginal dryness or dyspareunia, measured with an ordinal scale, and overall sexual health using the Female Sexual Function Index (FSFI). Postmenopausal women with a history of breast or gynecologic cancer who had completed primary treatment, had no evidence of disease, and reported at least moderate vaginal symptoms were eligible. The mean change from baseline to week 12 in the severity of vaginal dryness or dyspareunia for each DHEA dose was compared to PM and analyzed by two independent t tests using a Bonferroni correction.
    Results: Four hundred sixty-four women were randomized. All arms reported improvement in either dryness or dyspareunia. Neither DHEA dose was statistically significantly different from PM at 12 weeks (6.25 mg, p = .08; 3.25 mg, p = 0.48), although a significant difference at 8 weeks for 6.5 mg DHEA was observed (p = 0.005). Women on the 6.5 mg arm of DHEA reported significantly better sexual health on the FSFI (p < 0.001). There were no significant differences in provider-graded toxicities and few significant differences in self-reported side effects.
    Conclusion: PM and DHEA improved vaginal symptoms at 12 weeks. However, vaginal DHEA, 6.5 mg, significantly improved sexual health. Vaginal DHEA warrants further investigation in women with a history of cancer.
    MeSH term(s) Administration, Intravaginal ; Cancer Survivors ; Dehydroepiandrosterone/pharmacology ; Dehydroepiandrosterone/therapeutic use ; Female ; Humans ; Middle Aged ; Postmenopause ; Vaginal Diseases/drug therapy
    Chemical Substances Dehydroepiandrosterone (459AG36T1B)
    Language English
    Publishing date 2017-09-18
    Publishing country Germany
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1134446-5
    ISSN 1433-7339 ; 0941-4355
    ISSN (online) 1433-7339
    ISSN 0941-4355
    DOI 10.1007/s00520-017-3878-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3697: Show issues Location:
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