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  1. Article ; Online: Isolated Decreased Platelets in a Child: Thinking Beyond Immune Thrombocytopenia.

    Mittal, Shelly / Sahi, Puneet Kaur

    Indian pediatrics

    2023  Volume 60, Issue 9, Page(s) 773

    MeSH term(s) Child ; Humans ; Purpura, Thrombocytopenic, Idiopathic/diagnosis ; Blood Platelets ; Thrombocytopenia
    Language English
    Publishing date 2023-09-13
    Publishing country India
    Document type Letter
    ZDB-ID 402594-5
    ISSN 0974-7559 ; 0019-6061
    ISSN (online) 0974-7559
    ISSN 0019-6061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Cell-Based Gene Therapy for b-Thalassemia.

    Arya, Yajika / Sahi, Puneet Kaur

    Indian pediatrics

    2023  Volume 60, Issue 4, Page(s) 313–316

    Abstract: The United States Food and Drug Administration (FDA) approved betibeglogene autotemcel (beti-cel), the first cell-based gene therapy for adult and pediatric patients with b-thalassemia in August, 2022. This update details this and other novel therapies ... ...

    Abstract The United States Food and Drug Administration (FDA) approved betibeglogene autotemcel (beti-cel), the first cell-based gene therapy for adult and pediatric patients with b-thalassemia in August, 2022. This update details this and other novel therapies that have emerged in the treatment of b-thalassemia, apart from transfusion and iron chelation, with particular focus on newly approved gene therapy.
    MeSH term(s) Adult ; United States ; Humans ; Child ; Iron Chelating Agents/therapeutic use ; Iron/therapeutic use ; Iron Overload ; Thalassemia/drug therapy ; Genetic Therapy
    Chemical Substances Iron Chelating Agents ; Iron (E1UOL152H7) ; betibeglogene autotemcel
    Language English
    Publishing date 2023-03-31
    Publishing country India
    Document type Journal Article
    ZDB-ID 402594-5
    ISSN 0974-7559 ; 0019-6061
    ISSN (online) 0974-7559
    ISSN 0019-6061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Transition of Care for Patients with Thalassemia.

    Chandra, Jagdish / Sahi, Puneet Kaur

    Indian journal of pediatrics

    2023  Volume 90, Issue 12, Page(s) 1227–1231

    Abstract: Thalassemia is one of the most common hemoglobinopathies affecting a large number of people in India and other countries of South-East Asia. For patients with most severe form of the disease- Transfusion Dependent Thalassemia (TDT), stem cell ... ...

    Abstract Thalassemia is one of the most common hemoglobinopathies affecting a large number of people in India and other countries of South-East Asia. For patients with most severe form of the disease- Transfusion Dependent Thalassemia (TDT), stem cell transplantation or gene therapy are only curative treatment which are not available to most of the patients because of lack of experts, financial constraints and lack of suitable donors. In such situations, most cases are managed with regular blood transfusion and iron chelation therapy. With this treatment, over the years, survival of the patients has improved and 20-40% cases are entering into adulthood. In the absence of structured transition of care programs, currently most adult TDT patients are being managed by pediatricians. This article highlights the need for transition of care for TDT patients, barriers to transition and how to overcome the barriers and process of transition of care to adult care team. The importance of empowering the patients in self-management of the disease and educating the adult care team to achieve the desired outcome of transition program is highlighted.
    MeSH term(s) Adult ; Humans ; beta-Thalassemia/therapy ; Chelation Therapy ; Hematopoietic Stem Cell Transplantation ; Patient Transfer ; Stem Cell Transplantation ; Thalassemia/therapy ; Transition to Adult Care
    Language English
    Publishing date 2023-05-03
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-023-04595-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Pediatric Acute Cardiac Tamponade: A Conundrum Between Tuberculosis and COVID-19.

    Gupta, Arpita / Juneja, Monica / Sahi, Puneet Kaur

    Indian pediatrics

    2023  Volume 60, Issue 7, Page(s) 592–594

    MeSH term(s) Humans ; Child ; Cardiac Tamponade/diagnosis ; COVID-19/complications ; Tuberculosis
    Language English
    Publishing date 2023-07-08
    Publishing country India
    Document type Journal Article
    ZDB-ID 402594-5
    ISSN 0974-7559 ; 0019-6061
    ISSN (online) 0974-7559
    ISSN 0019-6061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Benign polyserositis and acalculous cholecystitis, a rare presentation of acute viral hepatitis A and E co-infection.

    Sahi, Puneet Kaur / Mazhari, Mohammad Yusuf Ali / Mandal, Anirban

    Tropical doctor

    2023  Volume 53, Issue 3, Page(s) 393–395

    MeSH term(s) Humans ; Acalculous Cholecystitis/diagnosis ; Acalculous Cholecystitis/etiology ; Coinfection/diagnosis ; Hepatitis A/complications ; Hepatitis A/diagnosis ; Acute Disease
    Language English
    Publishing date 2023-04-24
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 193169-6
    ISSN 1758-1133 ; 0049-4755
    ISSN (online) 1758-1133
    ISSN 0049-4755
    DOI 10.1177/00494755231170245
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Pediatric Hemato-Oncology Care Amid the COVID-19 Pandemic.

    Sahi, Puneet Kaur / Chandra, Jagdish

    Indian journal of pediatrics

    2021  Volume 88, Issue 3, Page(s) 221–224

    MeSH term(s) COVID-19 ; Child ; Hematology/trends ; Humans ; Medical Oncology/trends ; Pandemics ; Pediatrics/trends
    Language English
    Publishing date 2021-01-09
    Publishing country India
    Document type Editorial
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-020-03577-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Isolated Myocysticercosis of Anterior Chest Wall.

    Anand, Mugdha / Sahi, Puneet Kaur

    Indian journal of pediatrics

    2020  Volume 88, Issue 2, Page(s) 172–173

    MeSH term(s) Humans ; Scoliosis ; Thoracic Wall
    Language English
    Publishing date 2020-06-16
    Publishing country India
    Document type Letter
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-020-03407-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Pediatric Liver Abscess: Outcomes of Protocol-based Management and Predictors of Poor Outcome.

    Anand, Mugdha / Sahi, Puneet Kaur / Mandal, Anirban

    The Pediatric infectious disease journal

    2023  Volume 42, Issue 7, Page(s) 549–556

    Abstract: Background: Liver abscess (LA) is an important cause of morbidity in children, especially in tropical countries. There is a paucity of data in pediatric LA with no standard guidelines regarding the best modality of treatment and drainage. With a large ... ...

    Abstract Background: Liver abscess (LA) is an important cause of morbidity in children, especially in tropical countries. There is a paucity of data in pediatric LA with no standard guidelines regarding the best modality of treatment and drainage. With a large influx of patients at our center and protocol-based management; we aimed to study clinic-radiologic profile, risk factors, complications and outcomes of children with liver abscess and assessed possible predictors for poor outcomes.
    Materials and methods: This retrospective observational study was conducted from January 2019 to September 2019 at a tertiary care hospital in India. Records of all children (<12 years of age) with ultrasonographically diagnosed liver abscess were accessed for clinic-radiological and demographic profile, laboratory investigations, treatment, complications and outcomes. Patients were categorized into favorable or unfavorable groups based on predefined criteria and were compared for possible predictors of poor outcomes. Outcomes for the protocol-based management were analyzed.
    Results: There were 120 cases of pediatric liver abscess with a median age of 5 years at presentation. The commonest clinical features were fever (100%) and pain in the abdomen (89.16%). The majority of liver abscesses were solitary (78.4%) and in the right lobe (73.3%). Malnutrition was present in 27.5%, overcrowding for 76.5% of patients and worm infestation in 2.5% of patients. Age-related leukocytosis ( P = 0.004), neutrophilia ( P = 0.013), elevated Aspartate transaminase ( P = 0.008), elevated alanine transaminase ( P = 0.007) and hypoalbuminemia ( P = 0.014) were significantly more in the unfavorable group. Overall, 29.2% of patients underwent conservative management with antibiotics alone, 25.0% underwent percutaneous needle aspiration (PNA), 49.1% underwent ultrasound-guided percutaneous drain (PCD) insertion and open surgical drainage (OSD) was needed in a single patient. The success rate was 100% for conservative management, 76.6% for PNA, 94.7% for PCD and 100% for OSD with an overall mortality of 2.5%.
    Conclusions: Age-related leukocytosis, neutrophilia, elevated aspartate transaminase or alanine transaminase and hypoalbuminemia at presentation are predictors of poor outcomes in pediatric liver abscess. Protocol-based management leads to the appropriate use of PNA and PCD while decreasing mortality and morbidity related to either.
    MeSH term(s) Humans ; Alanine Transaminase ; Anti-Bacterial Agents/therapeutic use ; Drainage ; Hypoalbuminemia/drug therapy ; Leukocytosis ; Liver Abscess/therapy ; Retrospective Studies ; Treatment Outcome ; Ultrasonography, Interventional
    Chemical Substances Alanine Transaminase (EC 2.6.1.2) ; Anti-Bacterial Agents
    Language English
    Publishing date 2023-03-29
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000003923
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Vinblastine-induced Acral Hyperpigmentation.

    Chakraborti, Annesha / Sahi, Puneet Kaur

    Indian pediatrics

    2020  Volume 57, Issue 6, Page(s) 581–582

    MeSH term(s) Humans ; Hyperpigmentation/chemically induced ; Skin Neoplasms ; Vinblastine/adverse effects
    Chemical Substances Vinblastine (5V9KLZ54CY)
    Keywords covid19
    Language English
    Publishing date 2020-06-19
    Publishing country India
    Document type Letter
    ZDB-ID 402594-5
    ISSN 0974-7559 ; 0019-6061
    ISSN (online) 0974-7559
    ISSN 0019-6061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Hemophagocytic Lymphohistiocytosis (HLH) with Unusual Trigger.

    Mandal, Anirban / Sahi, Puneet Kaur

    The Journal of the Association of Physicians of India

    2019  Volume 67, Issue 1, Page(s) 101

    MeSH term(s) Humans ; Lymphohistiocytosis, Hemophagocytic
    Language English
    Publishing date 2019-03-31
    Publishing country India
    Document type Journal Article
    ZDB-ID 800766-4
    ISSN 0004-5772
    ISSN 0004-5772
    Database MEDical Literature Analysis and Retrieval System OnLINE

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