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Article: Impact of COVID-19 on Uro-Oncological Patients: A Comprehensive Review of the Literature.

Gavi, Filippo / Santoro, Paolo Emilio / Amantea, Carlotta / Russo, Pierluigi / Marino, Filippo / Borrelli, Ivan / Moscato, Umberto / Foschi, Nazario

Microorganisms

2023 Volume 11, Issue 1

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2023-01-10
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2720891-6
ISSN	2076-2607
ISSN	2076-2607
DOI	10.3390/microorganisms11010176
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Article ; Online: Vaccine-preventable diseases: Immune response in a large population of healthcare students.

Santoro, Paolo Emilio / Paladini, Andrea / Borrelli, Ivan / Amantea, Carlotta / Rossi, Maria Francesca / Fortunato, Corinna / Gualano, Maria Rosaria / Marchetti, Antonio / Cadeddu, Chiara / Moscato, Umberto

Vaccine

2024 Volume 42, Issue 4, Page(s) 930–936

Abstract: Background: Students in medicine and other health professions are exposed to numerous occupational hazards, primarily biological hazards, during their academic careers at university. The aim of the present study was to investigate the seroprevalence ... ...

Abstract	Background: Students in medicine and other health professions are exposed to numerous occupational hazards, primarily biological hazards, during their academic careers at university. The aim of the present study was to investigate the seroprevalence characteristics of anti-HBsAg, anti-Measles, anti-Mumps, anti-Rubella and anti-Varicella IgG antibodies in healthcare students of a large teaching hospital in Rome. Methods: To accomplish the study's aims, antibody serology data were gathered from students of Medicine and Surgery, Dentistry, and Health Professions at the Catholic University of the Sacred Heart (Rome Campus) during their first Health Surveillance visit, that took place from 2013 to 2023. Results: Our study sample included 2523 students, 44.4 % were protected against Hepatitis B, 87.3 % against measles, 85.5 % against mumps, 94.6 % rubella and 95.2 % against varicella. Differences in antibody coverage between age groups were statistically significant (p < 0.001), except for mumps. It found a lower probability of having seronegative anti-HBVs with an older date since the presumed primary vaccination. Conclusion: In our sample, seropositivity rate against vaccine-preventable diseases, especially for Hepatitis B, was often inadequate to prevent possible biological risks connected with the activities carried out on the ward.
MeSH term(s)	Humans ; Mumps/epidemiology ; Mumps/prevention & control ; Seroepidemiologic Studies ; Vaccine-Preventable Diseases ; Measles/epidemiology ; Measles/prevention & control ; Rubella/epidemiology ; Rubella/prevention & control ; Chickenpox/epidemiology ; Chickenpox/prevention & control ; Students ; Hepatitis B/epidemiology ; Hepatitis B/prevention & control ; Measles-Mumps-Rubella Vaccine ; Antibodies, Viral ; Immunity ; Delivery of Health Care ; Vaccination
Chemical Substances	Measles-Mumps-Rubella Vaccine ; Antibodies, Viral
Language	English
Publishing date	2024-01-20
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	605674-x
ISSN	1873-2518 ; 0264-410X
ISSN (online)	1873-2518
ISSN	0264-410X
DOI	10.1016/j.vaccine.2024.01.038
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Article ; Online: Sudden cardiac death among workers: a systematic review and meta-analysis.

Amantea, Carlotta / Pilia, Enrico / Rossi, Maria Francesca / Corona, Valerio Flavio / Amato, Giuseppe / Ciccu, Corrado / Gavi, Filippo / Santoro, Paolo Emilio / Borrelli, Ivan / Ricciardi, Walter / Gualano, Maria Rosaria / Moscato, Umberto

Systematic reviews

2024 Volume 13, Issue 1, Page(s) 84

Abstract: Objective: Sudden cardiac death (SCD) is a rare and yet unexplained condition. The most frequent cause is myocardial infarction, while a small proportion is due to arrhythmogenic syndromes (e.g., channelopathies). This systematic review and meta- ... ...

Abstract	Objective: Sudden cardiac death (SCD) is a rare and yet unexplained condition. The most frequent cause is myocardial infarction, while a small proportion is due to arrhythmogenic syndromes (e.g., channelopathies). This systematic review and meta-analysis aimed to provide a comprehensive overview of the prevalence and risk factors associated with SCD in workers. Material and methods: A search for eligible studies was performed utilizing three databases (PubMed, ISI Web of Knowledge, and Scopus). The inclusion criteria were fulfilled if sudden cardiac death due to channelopathy in workers was mentioned. Results: Out of the 1408 articles found across three databases, 6 articles were included in the systematic review but the meta-analysis was conducted on 3 studies The total sample included was 23,450 participants. The pooled prevalence of channelopathies in employees was 0.3% (95% CI 0.07-0.43%), of sudden cardiac death in employees was 2.8% (95% CI 0.37-5.20%), and of sudden cardiac death in employees with a diagnosis of cardiac channelopathies was 0.2% (95% CI 0.02- 0.30%). Conclusions: SCD is a serious and potentially preventable condition that can occur among workers. By identifying and addressing work-related risk factors, providing appropriate screening and interventions, and promoting healthy lifestyle behaviors, we can work to reduce the incidence of SCD and improve the cardiovascular health and well-being of workers.
MeSH term(s)	Humans ; Channelopathies/complications ; Death, Sudden, Cardiac/epidemiology ; Death, Sudden, Cardiac/etiology ; Death, Sudden, Cardiac/prevention & control ; Risk Factors ; Myocardial Infarction/complications ; Incidence
Language	English
Publishing date	2024-03-09
Publishing country	England
Document type	Meta-Analysis ; Systematic Review ; Journal Article
ZDB-ID	2662257-9
ISSN	2046-4053 ; 2046-4053
ISSN (online)	2046-4053
ISSN	2046-4053
DOI	10.1186/s13643-024-02504-5
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Article: Urological Safety and COVID-19 Vaccinations.

Foschi, Nazario / Santoro, Paolo Emilio / Borrelli, Ivan / Gavi, Filippo / Amantea, Carlotta / Russo, Pierluigi / Moscato, Umberto

Vaccines

2022 Volume 10, Issue 11

Abstract: Objective: To discuss the impact of COVID-19 vaccines on the urological field and to review the available data in the literature.: Material and methods: All the related reports and original articles discussing COVID-19 vaccines and their impact on ... ...

Abstract	Objective: To discuss the impact of COVID-19 vaccines on the urological field and to review the available data in the literature. Material and methods: All the related reports and original articles discussing COVID-19 vaccines and their impact on the urological field were searched in PubMed, Scopus, and Web of Science. Results: There are few published articles discussing the COVID-19 vaccine impact on urology. Vaccine safety was confirmed in this field as no major side effects were described. AKI (Acute Kidney Injury) was reported in selected populations. However, about 1% of the side effects was urological. Rare genital complications, low urinary tract symptoms, and occasional gross hematuria were reported. Fertility seems to be not impaired after vaccination. A potential misinterpretation of radiological findings in the oncological field has been reported. Conclusions: In the literature, there are few studies regarding COVID-19 vaccines and their impact on the urological and andrological fields. We need more studies and extended follow-ups after repeated vaccinations in order to have more corroborating data particularly in selected populations, such as kidney transplant recipients and oncological patients.
Language	English
Publishing date	2022-11-08
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2703319-3
ISSN	2076-393X
ISSN	2076-393X
DOI	10.3390/vaccines10111887
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Article: Employee Participation in Workplace Vaccination Campaigns: A Systematic Review and Meta-Analysis.

Gualano, Maria Rosaria / Santoro, Paolo Emilio / Borrelli, Ivan / Rossi, Maria Francesca / Amantea, Carlotta / Tumminello, Antonio / Daniele, Alessandra / Beccia, Flavia / Moscato, Umberto

Vaccines

2022 Volume 10, Issue 11

Abstract: To reduce vaccine-preventable diseases in workers, workplace vaccination campaigns can be implemented on-site. The aim of this systematic review was to evaluate adherence to workplace vaccination campaigns. Three databases, PubMed, ISI Web of Science, ... ...

Abstract	To reduce vaccine-preventable diseases in workers, workplace vaccination campaigns can be implemented on-site. The aim of this systematic review was to evaluate adherence to workplace vaccination campaigns. Three databases, PubMed, ISI Web of Science, and Scopus, were screened systematically for articles in English or Italian addressing participation in an on-site vaccination program by employees. The following data was extracted: authors, year, country, type of vaccine, type of workplace, sample size, vaccination rate. Data on the prevalence of flu vaccination were calculated and pooled using a random-effects model. Thirteen articles were included in the review, ten in the meta-analysis. Most studies were conducted in the USA (30.7%) and most vaccination campaigns were against influenza (69.2%), with a pooled estimate of 42% (95% CI: 0.25-0.60%); participation rate was highly variable, ranging from 88.9% for an influenza vaccination campaign to 5.7% for a Lyme disease vaccination campaign. Offering free on-site vaccination can be a successful tool to ensure adherence to vaccination campaigns and administration of all required doses according to the vaccine administration scheme. The occupational physician can play a key role in implementing workplace campaigns for employee mandatory vaccinations.
Language	English
Publishing date	2022-11-10
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2703319-3
ISSN	2076-393X
ISSN	2076-393X
DOI	10.3390/vaccines10111898
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Article ; Online: Hormones and Sex-Specific Medicine in Human Physiopathology.

Tokatli, Maria Raza / Sisti, Leuconoe Grazia / Marziali, Eleonora / Nachira, Lorenza / Rossi, Maria Francesca / Amantea, Carlotta / Moscato, Umberto / Malorni, Walter

Biomolecules

2022 Volume 12, Issue 3

Abstract: A prodigious increment of scientific evidence in both preclinical and clinical studies is narrowing a major gap in knowledge regarding sex-specific biological responses observed in numerous branches of clinical practices. Some paradigmatic examples ... ...

Abstract	A prodigious increment of scientific evidence in both preclinical and clinical studies is narrowing a major gap in knowledge regarding sex-specific biological responses observed in numerous branches of clinical practices. Some paradigmatic examples include neurodegenerative and mental disorders, immune-related disorders such as pathogenic infections and autoimmune diseases, oncologic conditions, and cardiovascular morbidities. The male-to-female proportion in a population is expressed as sex ratio and varies eminently with respect to the pathophysiology, natural history, incidence, prevalence, and mortality rates. The factors that determine this scenario incorporate both sex-associated biological differences and gender-dependent sociocultural issues. A broad narrative review focused on the current knowledge about the role of hormone regulation in gender medicine and gender peculiarities across key clinical areas is provided. Sex differences in immune response, cardiovascular diseases, neurological disorders, cancer, and COVID-19 are some of the hints reported. Moreover, gender implications in occupational health and health policy are offered to support the need for more personalized clinical medicine and public health approaches to achieve an ameliorated quality of life of patients and better outcomes in population health.
MeSH term(s)	COVID-19/epidemiology ; Female ; Hormones ; Humans ; Male ; Precision Medicine ; Quality of Life ; Sex Characteristics
Chemical Substances	Hormones
Language	English
Publishing date	2022-03-07
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2701262-1
ISSN	2218-273X ; 2218-273X
ISSN (online)	2218-273X
ISSN	2218-273X
DOI	10.3390/biom12030413
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Article ; Online: Alcohol Consumption in the Workplace: A Comparison between European Union Countries' Policies.

Borrelli, Ivan / Santoro, Paolo Emilio / Gualano, Maria Rosaria / Perrotta, Antongiulio / Daniele, Alessandra / Amantea, Carlotta / Moscato, Umberto

International journal of environmental research and public health

2022 Volume 19, Issue 24

Abstract: Background: Alcohol use is an ever-growing phenomenon in the population, consumption data indicate that 5-20% of the European working population have serious problems related to alcohol. The use of alcohol constitutes a risk to the health and safety of ... ...

Abstract	Background: Alcohol use is an ever-growing phenomenon in the population, consumption data indicate that 5-20% of the European working population have serious problems related to alcohol. The use of alcohol constitutes a risk to the health and safety of workers as well as to the safety of the general population. The present work aims to address the problem of alcohol intake in occupational settings by comparatively analyzing alcohol consumption behavior within the 27 countries of the European Union. Methods: The purpose of this research is to analyze the differences between the 27 countries of the European Union in the application of measures to assess and manage the risk of alcohol intake in occupational settings. Results: An examination of the legislation and guidelines of the different countries reveals profound differences in the management of the problem of alcohol in the workplace. The discrepancy is very wide that it ranges from the complete absence of legislative restrictions on a national level in some countries to highly restrictive measures with severe sanctions in others. Conclusions: It would be appropriate-also for the purpose of ease of movement of workers within the European Community-to find shared management models useful for protecting the health and safety of workers and the general population.
MeSH term(s)	Humans ; European Union ; Alcohol Drinking/epidemiology ; Policy ; Workplace
Language	English
Publishing date	2022-12-17
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph192416964
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Article ; Online: Psychological and Mental Sequelae in Elite Athletes with Previous SARS-CoV-2 Infection: A Systematic Review.

Corona, Valerio Flavio / Gualano, Maria Rosaria / Rossi, Maria Francesca / Valz Gris, Angelica / Amantea, Carlotta / Moscato, Umberto / Ricciardi, Walter

International journal of environmental research and public health

2022 Volume 19, Issue 24

Abstract: During the COVID-19 pandemic, many athletes from several sporting disciplines were infected with the SARS-CoV-2. The aim of this systematic review is to summarize the current scientific evidence on the psychological sequelae and mental health of elite ... ...

Abstract	During the COVID-19 pandemic, many athletes from several sporting disciplines were infected with the SARS-CoV-2. The aim of this systematic review is to summarize the current scientific evidence on the psychological sequelae and mental health of elite athletes who have been infected by the virus. The review was performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Statement; three databases were searched: PubMed, ISI Web of Knowledge, and Scopus. The initial search resulted in 2420 studies; after duplicate removal and screening by title and abstract, 41 articles were screened by full-text. A total of four eligible articles were included in the review. All included articles measured depression and anxiety in athletes who had suffered from COVID-19, while in three papers levels of stress were measured. Overall, the only two questionnaires used in more than one study were the DASS-21 and the APSQ. In our systematic review, we highlighted that mental and psychological health in elite athletes has the same importance as physical health. This statement suggests that these examinations should be introduced and performed during the competitive sports' medical examinations conducted at the start of the sporting season, which currently consists only of the examination of physical parameters. Due to lack of studies on the topic, the results of our review show that mental health in athletes with a history of SARS-CoV-2 infection is an issue that requires more investigation, considering the evidence of clinical consequences. The importance of post-infection psychological sequelae is significant in assessing possible repercussions on the athletes' sporting performance.
MeSH term(s)	Humans ; COVID-19/epidemiology ; SARS-CoV-2 ; Pandemics ; Athletes/psychology ; Sports
Language	English
Publishing date	2022-12-07
Publishing country	Switzerland
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph192416377
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Article ; Online: Returning to work and the impact of post COVID-19 condition: A systematic review.

Gualano, Maria Rosaria / Rossi, Maria Francesca / Borrelli, Ivan / Santoro, Paolo Emilio / Amantea, Carlotta / Daniele, Alessandra / Tumminello, Antonio / Moscato, Umberto

Work (Reading, Mass.)

2022 Volume 73, Issue 2, Page(s) 405–413

Abstract: Background: The COVID-19 pandemic is still ongoing, with rapidly increasing cases all over the world, and the emerging issue of post COVID-19 (or Long COVID-19) condition is impacting the occupational world.: Objective: The aim of this systematic ... ...

Abstract	Background: The COVID-19 pandemic is still ongoing, with rapidly increasing cases all over the world, and the emerging issue of post COVID-19 (or Long COVID-19) condition is impacting the occupational world. Objective: The aim of this systematic review was to evaluate the impact of lasting COVID-19 symptoms or disability on the working population upon their return to employment. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Statements we performed a systematic review in December 2021, screening three databases (PubMed, ISI Web of Knowledge, Scopus), for articles investigating return to work in patients that were previously hospitalized due to COVID-19. A hand-searched was then performed through the references of the included systematic review. A quality assessment was performed on the included studies. Results: Out of the 263 articles found through the initial search, 11 studies were included in this systematic review. The selected studies were divided based on follow-up time, in two months follow-up, follow-up between two and six months, and six months follow-up. All the studies highlighted an important impact of post COVID-19 condition in returning to work after being hospitalized, with differences based on follow-up time, home Country and mean/median age of the sample considered. Conclusions: This review highlighted post COVID-19 condition as a rising problem in occupational medicine, with consequences on workers' quality of life and productivity. The role of occupational physicians could be essential in applying limitations to work duties or hours and facilitating the return to employment in workers with a post COVID-19 condition.
MeSH term(s)	Humans ; COVID-19/epidemiology ; Pandemics ; Quality of Life ; World Health Organization
Language	English
Publishing date	2022-07-09
Publishing country	Netherlands
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	1394194-x
ISSN	1875-9270 ; 1051-9815
ISSN (online)	1875-9270
ISSN	1051-9815
DOI	10.3233/WOR-220103
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Article ; Online: TElewoRk-RelAted Stress (TERRA), Psychological and Physical Strain of Working From Home During the COVID-19 Pandemic: A Systematic Review.

Gualano, Maria Rosaria / Santoro, Paolo Emilio / Borrelli, Ivan / Rossi, Maria Francesca / Amantea, Carlotta / Daniele, Alessandra / Moscato, Umberto

Workplace health & safety

2022 Volume 71, Issue 2, Page(s) 58–67

Abstract: Background: Many workers shifted to working from home due to the COVID-19 pandemic. This review aims to investigate if this sudden change caused an increase in TElewoRk-RelAted stress (TERRA) which is defined as physical and mental stress caused by ... ...

Abstract	Background: Many workers shifted to working from home due to the COVID-19 pandemic. This review aims to investigate if this sudden change caused an increase in TElewoRk-RelAted stress (TERRA) which is defined as physical and mental stress caused by telework. Methods: A systematic review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines was performed of three scientific databases (PubMed, ISI Web of Knowledge, and Scopus), which also included a quality assessment. Articles measuring stress, psychological or physical, in remote workers, published from December 2019 through August 2021 were included in the review. Results were extracted by reporting: authors, country, study design, type of workers, sample, questionnaires and measurements, and outcomes. Data were synthesized quantitatively for country, type of workers, and outcomes. Results: Out of the 518 articles found in the three databases, 19 articles were included in the systematic review (10,012 participants overall), and 78.9% of these highlighted an increase in TERRA levels in remote workers. Among 85.7% of the studies considering gender as a variable, TERRA levels were higher in female workers. Twelve (63.2%) of the studies investigated psychological well-being, two (10.5%) focused on the physical well-being of remote workers, three (15.8%) investigated both, and two studies had other outcomes (10.5%). Conclusions: Considering the redefinition of workplaces dictated by the COVID-19 pandemic, this review highlights the emerging issue of remote work and the use of technology in working from home, emphasizing a rapidly growing occupational health problem. Remote workers need to be provided with emotional and technical support to prevent TERRA in remote workers.
MeSH term(s)	Female ; Humans ; COVID-19/prevention & control ; Emotions ; Occupational Diseases ; Pandemics ; Stress, Psychological ; Teleworking ; Workplace ; Occupational Stress ; Occupational Health
Language	English
Publishing date	2022-11-16
Publishing country	United States
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	2649181-3
ISSN	2165-0969 ; 2165-0799
ISSN (online)	2165-0969
ISSN	2165-0799
DOI	10.1177/21650799221119155
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