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Article: Intravaginal Application of Topical Black Salve for High-Grade Cervical Intraepithelial Neoplasia.

Ayoub, Peter J / Parise, Angela

The Ochsner journal

2020 Volume 20, Issue 4, Page(s) 456–458

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2020-12-09
Publishing country	United States
Document type	Case Reports
ISSN	1524-5012
ISSN	1524-5012
DOI	10.31486/toj.19.0044
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Article ; Online: Coronary physiology and percutaneous intervention managed with gadolinium road mapping and intravascular ultrasound in hyperthyroidism.

Tajti, Peter / Ayoub, Mohamed / Nuehrenberg, Thomas / Mashayekhi, Kambis

Cardiology journal

2021 Volume 28, Issue 4, Page(s) 642–645

MeSH term(s)	Coronary Angiography ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/surgery ; Coronary Vessels/diagnostic imaging ; Gadolinium ; Humans ; Hyperthyroidism/diagnosis ; Percutaneous Coronary Intervention ; Treatment Outcome ; Ultrasonography, Interventional
Chemical Substances	Gadolinium (AU0V1LM3JT)
Language	English
Publishing date	2021-03-01
Publishing country	Poland
Document type	Letter
ZDB-ID	2488680-4
ISSN	1898-018X ; 1897-5593
ISSN (online)	1898-018X
ISSN	1897-5593
DOI	10.5603/CJ.a2021.0027
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Article ; Online: Accuracy and reliability of automated three-dimensional facial landmarking in medical and biological studies. A systematic review.

Al-Baker, Bodore / Alkalaly, Abdullah / Ayoub, Ashraf / Ju, Xiangyang / Mossey, Peter

European journal of orthodontics

2023 Volume 45, Issue 4, Page(s) 382–395

Abstract: Background: 3D facial landmarking is becoming a fundamental part of clinical and biological applications. Manual landmarking is time consuming and prone to cumulative errors, so attempts have been made to automate 3D facial landmarking. However, data in ...

Abstract	Background: 3D facial landmarking is becoming a fundamental part of clinical and biological applications. Manual landmarking is time consuming and prone to cumulative errors, so attempts have been made to automate 3D facial landmarking. However, data in the literature are sparse. Objectives: The objectives of this study are to investigate current evidence for the accuracy and reliability of various 3D facial automated landmarking methods used in medical and biological studies and evaluate their performance against the manual annotation method. Search methods: Electronic and manual searches of the literature were performed in April 2021. Selection criteria: Only studies that were published in English and evaluated the accuracy of automated landmarking algorithms in 3D facial images for medical or biological settings were included. Data collection and analysis: Two authors independently screened the articles for eligibility. The QUADAS-2 tool was used for the quality analysis of the included studies. Due to the heterogeneity of the selected studies, a meta-analysis was not possible, so a narrative synthesis of the findings was performed. Results: From 1002 identified records, after applying the inclusion and exclusion criteria, 14 articles were ultimately selected, read, and critically analysed. Different algorithms were used for the automated 3D landmarking of various numbers of facial landmarks ranging from 10 to 29 landmarks. The average difference between the manual and automated methods ranged from 0.67 to 4.73 mm, and the best performance was achieved using deep learning models. Poor study design and inadequate reporting were found in the implementation of the reference standards and population selection for the intended studies, which could have led to overfitting of the tested algorithm. Limitations: This systematic review was limited by the quality of the included studies and uncovered several methodological limitations evident in the corresponding literature. Conclusion and implications: Compared to manual landmarking, automated Landmark localization of individual facial landmarks reported in the literature is not accurate enough to allow their use for clinical purposes. This result indicates that automatic facial landmarking is still developing, and further studies are required to develop a system that could match or exceed the performance of the current gold standard. Registration: PROSPERO: CRD42021241531.
MeSH term(s)	Humans ; Reproducibility of Results ; Face ; Imaging, Three-Dimensional/methods ; Algorithms
Language	English
Publishing date	2023-04-28
Publishing country	England
Document type	Systematic Review ; Journal Article
ZDB-ID	423731-6
ISSN	1460-2210 ; 0141-5387
ISSN (online)	1460-2210
ISSN	0141-5387
DOI	10.1093/ejo/cjac077
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Article: Safety and Long-Term Outcomes of Rotablation in Patients with Reduced (<50%) Left Ventricular Ejection Fraction (rEF) (The Rota-REF Study).

Ayoub, Mohamed / Tajti, Péter / Akin, Ibrahim / Behnes, Michael / Schupp, Tobias / Forner, Jan / Omran, Hazem / Westermann, Dirk / Rudolph, Volker / Mashayekhi, Kambis

Journal of clinical medicine

2023 Volume 12, Issue 17

Abstract: Clinical outcomes in patients with reduced left ventricular systolic function undergoing rotational atherectomy (RA) for percutaneous coronary intervention (PCI) remain understudied. Our study sought to evaluate the impact of RA-PCI in patients with LV ... ...

Abstract	Clinical outcomes in patients with reduced left ventricular systolic function undergoing rotational atherectomy (RA) for percutaneous coronary intervention (PCI) remain understudied. Our study sought to evaluate the impact of RA-PCI in patients with LV systolic dysfunction on long-term outcomes. Between 2015 and 2019, 4941 patients with reduced LV function (rEF) undergoing PCI (with or without RA) were included in the hospital database. The primary endpoint was in-hospital major adverse cardiovascular and cerebral events (MACCE). The secondary endpoint was 3-year MACCE. In-hospital MACCE rates were significantly higher in RA-PCI compared to standard PCI without RA (PCI) (7.6% vs. 3.9%,
Language	English
Publishing date	2023-08-30
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12175640
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Article: A Novel Strategy for Emergency Treatment of Coronary Perforations by Placing a Drug-Eluting Stent before Sealing off the Leakage with a Covered Stent to Improve Long-Term Outcomes in Patients with Coronary Artery Perforations.

Ayoub, Mohamed / Corpataux, Noé / Tajti, Péter / Behnes, Michael / Schupp, Tobias / Forner, Jan / Akin, Ibrahim / Westermann, Dirk / Rudolph, Volker / Mashayekhi, Kambis

Journal of personalized medicine

2023 Volume 13, Issue 11

Abstract: We aimed to investigate the safety, feasibility, and long-term results of drug-eluting stent implantation before covered stents for treating coronary artery perforation (CAP). Between 2015 and 2020, 12,733 patients undergoing percutaneous coronary ... ...

Abstract	We aimed to investigate the safety, feasibility, and long-term results of drug-eluting stent implantation before covered stents for treating coronary artery perforation (CAP). Between 2015 and 2020, 12,733 patients undergoing percutaneous coronary intervention (PCI) were retrospectively analyzed. The primary endpoint was 1-year target lesion revascularization (TLR), whereas secondary endpoints included the rate of major adverse cardiac and cerebrovascular events (MACCE) and all-cause death at 1 year. A total of 159 patients with CAP were identified during the study period, of whom 47.2% (n = 75) were treated with a covered stent (CS group) because of complex and/or severe CAP and 84 (52.8%) without (non-CS group). In the majority of patients, emergency drug-eluting stent placement before covered stent implantation was feasible (n = 69, 82%). There were no significant differences among patients treated with or without a covered stent in terms of primary or secondary clinical endpoints: a similar rate of TLR (18.67% vs. 21.43%,
Language	English
Publishing date	2023-10-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662248-8
ISSN	2075-4426
ISSN	2075-4426
DOI	10.3390/jpm13111542
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Article ; Online: Management of Microcatheter Fracture in Complex Percutaneous Coronary Intervention With Laser Atherectomy.

Tajti, Peter / Ayoub, Mohamed / Loffelhardt, Nicolaus / Mashayekhi, Kambis

Cardiovascular revascularization medicine : including molecular interventions

2020 Volume 28S, Page(s) 208–211

Abstract: Background/objective: Microcatheters and dedicated guidewires for both chronic total occlusion (CTO) and non-CTO percutaneous coronary intervention (PCI) are increasingly being used to overcome complex coronary anatomy with severe tortuosity and ... ...

Abstract	Background/objective: Microcatheters and dedicated guidewires for both chronic total occlusion (CTO) and non-CTO percutaneous coronary intervention (PCI) are increasingly being used to overcome complex coronary anatomy with severe tortuosity and calcification. In extremely resistant lesions, a potential over-rotation and device fatigue may result in entrapment or even fracture causing abrupt vessel closure and hinder successful revascularization. Method/result: We demonstrate two consecutive cases complicated with dislodged microcatheter tip which was rescued uniquely with coronary laser atherectomy. We describe an algorithmic approach for management of microcatheter fracture which are increasingly occur in contemporary practice of complex PCI. Conclusion: In summary, our cases illustrate the feasibility of using coronary excimer laser system to release fractured and entrapped intracoronary MC tips when other conventional percutaneous techniques fail.
MeSH term(s)	Atherectomy, Coronary/adverse effects ; Chronic Disease ; Coronary Angiography ; Coronary Occlusion/diagnostic imaging ; Coronary Occlusion/surgery ; Humans ; Lasers, Excimer/therapeutic use ; Percutaneous Coronary Intervention/adverse effects ; Treatment Outcome
Language	English
Publishing date	2020-12-16
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2212113-4
ISSN	1878-0938 ; 1553-8389
ISSN (online)	1878-0938
ISSN	1553-8389
DOI	10.1016/j.carrev.2020.12.017
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Zs.A 5562: Show issues

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Article ; Online: Surgical Complications Requiring Reoperation in Open Versus Minimally Invasive Radical Nephrectomy: A Contemporary Analysis of the National Surgical Quality Improvement Program.

El-Asmar, Jose M / Ayoub, Christian Habib / Kfoury, Peter / Abou-Mrad, Anthony / El-Hajj, Albert

World journal of surgery

2022 Volume 47, Issue 4, Page(s) 856–862

Abstract: Background: To explore reoperation rates for different radical nephrectomy (RN) approaches that are experiencing a shift from open radical nephrectomy (ORN) toward minimally invasive surgery (MIS), we aimed to compare reoperation rates along with their ... ...

Abstract	Background: To explore reoperation rates for different radical nephrectomy (RN) approaches that are experiencing a shift from open radical nephrectomy (ORN) toward minimally invasive surgery (MIS), we aimed to compare reoperation rates along with their culprit etiologies between the different types of surgical approaches for RN. Methods: The national surgical quality improvement program dataset was used to select patients who underwent RN between the years 2012-2019. A 1:1 propensity score matched analysis was used. Reoperation rates and causes were then compared between open and MIS approach. Results: The propensity matched cohort included 15,294 patients. Reoperation rates due to large bowel injury (0.01 vs. 0.14%), vascular injury (0.07 vs. 0.22%), and other abdominal (0.5 vs. 0.77%) were more common in ORN as compared to MIS (MIS vs. ORN, respectively, p < 0.034). Reoperation due to hernia (0.14 vs. 0.03%) was more common in MIS as compared to ORN (p = 0.027). No difference was seen for small bowel injury and incision/wound debridement. General reoperation (1.61 vs. 2.22%) and mortality (0.57 vs. 1.47%) were also more common in ORN as compared to MIS (p < 0.008). Conclusion: Reoperation due to large bowel injury, vascular injury, and other abdominal was more likely to occur in ORN. Whereas reoperation due to hernia was more likely to occur in MIS. Surgical approach was an independent risk factor for immediate and early reoperation rates in RN patients. These results could be used to counsel patients pre-operatively on possible surgical approaches and complications.
MeSH term(s)	Humans ; Reoperation ; Quality Improvement ; Minimally Invasive Surgical Procedures/adverse effects ; Minimally Invasive Surgical Procedures/methods ; Nephrectomy/adverse effects ; Nephrectomy/methods ; Risk Factors ; Retrospective Studies
Language	English
Publishing date	2022-12-31
Publishing country	United States
Document type	Journal Article
ZDB-ID	224043-9
ISSN	1432-2323 ; 0364-2313
ISSN (online)	1432-2323
ISSN	0364-2313
DOI	10.1007/s00268-022-06869-3
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Article ; Online: Procedural outcomes of chronic total occlusion percutaneous coronary interventions in patients with acute kidney injury.

Tajti, Peter / Ayoub, Mohamed / Ahres, Abdelkrim / Rahimi, Faridun / Behnes, Michael / Buettner, Heinz-Joachim / Neumann, Franz-Josef / Westermann, Dirk / Mashayekhi, Kambis

Cardiology journal

2023 Volume 31, Issue 1, Page(s) 84–94

Abstract: Background: The prognostic impact of contrast-associated acute kidney injury (CA-AKI) in patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI) remains underestimated.: Methods: We examined 2707 consecutive ... ...

Abstract	Background: The prognostic impact of contrast-associated acute kidney injury (CA-AKI) in patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI) remains underestimated. Methods: We examined 2707 consecutive procedures performed in a referral CTO center between 2015 and 2019. CA-AKI was defined as an increase in serum creatinine ≥ 0.3 mg/dL or ≥ 50% within 48 h post-PCI. Primary endpoints were in-hospital major adverse cardiac and cerebrovascular events (MACCE, composite of all-cause death, myocardial infarction, target vessel revascularization, stroke) and at one year of follow-up. Results: The overall incidence of CA-AKI was 11.5%. Technical success was comparable (87.2% vs. 90.5%, p = 0.056) whereas procedural success was lower in the CA-AKI group (84.3% vs. 89.7%, p = 0.004). Overall in-hospital MACCE was 1.3%, and it was similar in patients with and without CA-AKI (1.6% vs. 1.3%, p = 0.655); however, the rate of pericardial tamponade requiring pericardiocentesis was significantly higher in patients with CA-AKI (2.2% vs. 0.5%, p = 0.001). In multivariate analysis, CA-AKI was not independently associated with higher risk for in-hospital MACCE (adjusted odds ratio [OR] 1.34, 95% confidence intervals [CI] 0.45-3.19, p = 0.563). At a median follow-up time of 14 months (interquartile range [IQR], 11 to 35 months), one-year MACCE was significantly higher in patients with vs. without CA-AKI (20.8% vs. 12.8%, p < 0.001), and CA-AKI increased the risk for one-year MACCE (adjusted hazard ratio [HR] 1.46, 95% CI 1.07-1.95, p = 0.017) following CTO PCI. Conclusions: CA-AKI in patients undergoing CTO PCI occurs in approximately one out of 10 patients. Our study highlights that patients developing CA-AKI are at increased risk for long-term MACCE.
MeSH term(s)	Humans ; Treatment Outcome ; Percutaneous Coronary Intervention/adverse effects ; Percutaneous Coronary Intervention/methods ; Myocardial Infarction/etiology ; Prognosis ; Acute Kidney Injury/chemically induced ; Acute Kidney Injury/diagnosis ; Acute Kidney Injury/epidemiology ; Coronary Occlusion/diagnosis ; Coronary Occlusion/surgery ; Coronary Occlusion/etiology ; Risk Factors
Language	English
Publishing date	2023-01-02
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2488680-4
ISSN	1898-018X ; 1897-5593
ISSN (online)	1898-018X
ISSN	1897-5593
DOI	10.5603/CJ.a2022.0121
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Article: Digital technology and mental health during the COVID-19 pandemic: a narrative review with a focus on depression, anxiety, stress, and trauma.

Guest, Paul C / Vasilevska, Veronika / Al-Hamadi, Ayoub / Eder, Julia / Falkai, Peter / Steiner, Johann

Frontiers in psychiatry

2023 Volume 14, Page(s) 1227426

Abstract: The sudden appearance and devastating effects of the COVID-19 pandemic resulted in the need for multiple adaptive changes in societies, business operations and healthcare systems across the world. This review describes the development and increased use ... ...

Abstract	The sudden appearance and devastating effects of the COVID-19 pandemic resulted in the need for multiple adaptive changes in societies, business operations and healthcare systems across the world. This review describes the development and increased use of digital technologies such as chat bots, electronic diaries, online questionnaires and even video gameplay to maintain effective treatment standards for individuals with mental health conditions such as depression, anxiety and post-traumatic stress syndrome. We describe how these approaches have been applied to help meet the challenges of the pandemic in delivering mental healthcare solutions. The main focus of this narrative review is on describing how these digital platforms have been used in diagnostics, patient monitoring and as a treatment option for the general public, as well as for frontline medical staff suffering with mental health issues.
Language	English
Publishing date	2023-12-22
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2564218-2
ISSN	1664-0640
ISSN	1664-0640
DOI	10.3389/fpsyt.2023.1227426
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Article: Visszérműtét lézerrel.

Bihari, Imre / Ayoub, George / Bokros, Szilvia / Bihari, Péter

Magyar sebeszet

2018 Volume 71, Issue 3, Page(s) 134–141

Abstract: Introduction: With the development of medicine, technical inventions have been intoduced into the therapy of varicose veins, such as ultrasound examination and laser treatment.: Patients and methods: Over 11 years 1729 laser surgery were performed on ...

Title translation	Laser surgery on varicose veins.
Abstract	Introduction: With the development of medicine, technical inventions have been intoduced into the therapy of varicose veins, such as ultrasound examination and laser treatment. Patients and methods: Over 11 years 1729 laser surgery were performed on varicose veins. Junctions of saphenous veins, saphenous stems and perforator veins were treated with lasers, but reticular and spider veins were treated with other methods. The most important elements of laser surgery are the introduction of the laser fibre into the lumen of the vein and delivering the laser energy. All of this is performed without incisions under ultrasound guidance. Laser crossectomy is an innovation in our technique. This procedure is performed under a combination of local and intravenous anaesthesia. Results: After 1 year 58% of operated legs (998) were checked (mean 3.3 years) and recurrent varicosity was found in 114 legs (11.4%). Recurrences were found mainly in those cases which would have been excluded from other studies, but in everyday practice they occur in a high percentage, such as being overweight, after delivery and previously operated cases. In selected cases, the recurrence rate is only 6.0%. Complications after laser surgery are less frequent than following classic varicose vein surgery. Conclusions: According to international guidelines and this study, endovascular interventions can be recommended instead of classic varicose vein surgery because they are less demanding, and cause fewer complications. Using laser crossectomy, the number of early recurrences decreases. All stem varicosities are suitable for laser surgery.
MeSH term(s)	Adult ; Female ; Humans ; Laser Therapy ; Treatment Outcome ; Varicose Veins/surgery
Language	Hungarian
Publishing date	2018-09-18
Publishing country	Hungary
Document type	Journal Article
ZDB-ID	414068-0
ISSN	0025-0295
ISSN	0025-0295
DOI	10.1556/1046.71.2018.3.4
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