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  1. Article ; Online: Neonatal ocular prophylaxis in the United States: is it still necessary?

    Franco, Susannah / Hammerschlag, Margaret R

    Expert review of anti-infective therapy

    2023  Volume 21, Issue 5, Page(s) 503–511

    Abstract: Introduction: Much has changed since Credé reported that silver nitrate decreases the incidence of ophthalmia neonatorum. Prenatal screening and treatment of pregnant women for : Areas covered: This article addresses the altered epidemiology of ... ...

    Abstract Introduction: Much has changed since Credé reported that silver nitrate decreases the incidence of ophthalmia neonatorum. Prenatal screening and treatment of pregnant women for
    Areas covered: This article addresses the altered epidemiology of ophthalmia neonatorum in the U.S. since prophylactic practices began, the lack of data supporting ophthalmic erythromycin for prevention of neonatal gonococcal and chlamydial conjunctivitis, and the impact of prenatal screening and treatment of pregnant women for
    Expert opinion: Administration of erythromycin ophthalmic ointment for the prevention of neonatal conjunctivitis is not literature-supported. Prenatal screening and treatment of pregnant women is the most effective way to prevent ophthalmia neonatorum. National mandates for prophylaxis should be withdrawn.
    MeSH term(s) Infant, Newborn ; Female ; Humans ; Pregnancy ; United States/epidemiology ; Ophthalmia Neonatorum/diagnosis ; Ophthalmia Neonatorum/drug therapy ; Ophthalmia Neonatorum/epidemiology ; Anti-Bacterial Agents/therapeutic use ; Ointments/therapeutic use ; Drug Resistance, Bacterial ; Macrolides/therapeutic use ; Gonorrhea/drug therapy ; Gonorrhea/epidemiology ; Gonorrhea/prevention & control ; Erythromycin/therapeutic use ; Chlamydia trachomatis
    Chemical Substances Anti-Bacterial Agents ; Ointments ; Macrolides ; Erythromycin (63937KV33D)
    Language English
    Publishing date 2023-01-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2181279-2
    ISSN 1744-8336 ; 1478-7210
    ISSN (online) 1744-8336
    ISSN 1478-7210
    DOI 10.1080/14787210.2023.2172401
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Diagnostic Challenges of Urinary Schistosomiasis Among Adolescent Immigrants in New York City: A Report of Three Cases.

    Shaoba, Asma / Hammerschlag, Margaret R / Bamgbola, Oluwatoyin F

    The Pediatric infectious disease journal

    2023  Volume 42, Issue 3, Page(s) e95–e97

    Abstract: Urinary schistosomiasis is endemic in the tropical world. It is uncommon in geographical areas with advanced public health resources. Modern immigration from endemic communities to the United States supports the need to improve our diagnostic awareness. ... ...

    Abstract Urinary schistosomiasis is endemic in the tropical world. It is uncommon in geographical areas with advanced public health resources. Modern immigration from endemic communities to the United States supports the need to improve our diagnostic awareness. We describe 3 Brooklyn adolescent immigrants from Africa with urinary schistosomiasis, all of whom had an initial misdiagnosis that led to delay in therapeutic intervention.
    MeSH term(s) Humans ; Adolescent ; United States ; Schistosomiasis haematobia/epidemiology ; New York City ; Emigrants and Immigrants ; Africa
    Language English
    Publishing date 2023-01-25
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000003807
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: In Vitro

    Kohlhoff, Stephan / Hammerschlag, Margaret R

    Antimicrobial agents and chemotherapy

    2021  Volume 65, Issue 9, Page(s) e0058521

    MeSH term(s) Chlamydia Infections ; Chlamydophila pneumoniae ; Humans ; Ketolides ; Lactones ; Microbial Sensitivity Tests
    Chemical Substances Ketolides ; Lactones ; nafithromycin (75F74Y2R70)
    Language English
    Publishing date 2021-08-17
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 217602-6
    ISSN 1098-6596 ; 0066-4804
    ISSN (online) 1098-6596
    ISSN 0066-4804
    DOI 10.1128/AAC.00585-21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Coronavirus-19 infection and vaccination rates in a private school in Brooklyn, New York.

    Smith-Norowitz, Tamar A / Kohlhoff, Stephan / Hammerschlag, Margaret R

    European journal of clinical investigation

    2022  Volume 52, Issue 4, Page(s) e13747

    MeSH term(s) Coronavirus ; Humans ; New York/epidemiology ; Schools ; Vaccination
    Language English
    Publishing date 2022-01-14
    Publishing country England
    Document type Letter
    ZDB-ID 186196-7
    ISSN 1365-2362 ; 0014-2972 ; 0960-135X
    ISSN (online) 1365-2362
    ISSN 0014-2972 ; 0960-135X
    DOI 10.1111/eci.13747
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    Zs.A 677: Show issues Location:
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  5. Article ; Online: Azithromycin in the treatment of rectogenital

    Hammerschlag, Margaret R / Sharma, Roopali

    Expert review of anti-infective therapy

    2020  Volume 19, Issue 4, Page(s) 487–493

    Abstract: Introduction: Azithromycin was recommended as the first-line therapeutic regimen for treatment of genital infections in men and women by the Centers for Disease Control in 1998. A series of studies of azithromycin for treatment of rectal chlamydial ... ...

    Abstract Introduction: Azithromycin was recommended as the first-line therapeutic regimen for treatment of genital infections in men and women by the Centers for Disease Control in 1998. A series of studies of azithromycin for treatment of rectal chlamydial infection in men who have sex with men (MSM) found that azithromycin was significantly less effective than doxycycline.
    Areas covered: Literature on treatment of rectal
    Expert opinion: The available data suggests that single-dose azithromycin is not as effective as azithromycin for the treatment of rectal infection in MSM and women. Most of these data have been retrospective or from observational studies. Final recommendations will depend on the outcome of prospective, randomized, treatment studies. We may also need to examine other dosage regimens for azithromycin.
    MeSH term(s) Anti-Bacterial Agents/administration & dosage ; Azithromycin/administration & dosage ; Chlamydia Infections/drug therapy ; Chlamydia Infections/microbiology ; Chlamydia trachomatis/drug effects ; Chlamydia trachomatis/isolation & purification ; Doxycycline/administration & dosage ; Female ; Genital Diseases, Female/drug therapy ; Genital Diseases, Female/microbiology ; Genital Diseases, Male/drug therapy ; Genital Diseases, Male/microbiology ; Humans ; Male ; Rectal Diseases/drug therapy ; Rectal Diseases/microbiology ; Sexual and Gender Minorities
    Chemical Substances Anti-Bacterial Agents ; Azithromycin (83905-01-5) ; Doxycycline (N12000U13O)
    Language English
    Publishing date 2020-10-18
    Publishing country England
    Document type Comparative Study ; Journal Article ; Review
    ZDB-ID 2181279-2
    ISSN 1744-8336 ; 1478-7210
    ISSN (online) 1744-8336
    ISSN 1478-7210
    DOI 10.1080/14787210.2021.1834850
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Coronavirus disease 2019 (COVID-19) infection rates in a private school in Brooklyn, New York.

    Smith-Norowitz, Tamar A / Hammerschlag, Margaret R / Kohlhoff, Stephan

    Acta paediatrica (Oslo, Norway : 1992)

    2021  Volume 110, Issue 5, Page(s) 1569–1570

    MeSH term(s) COVID-19/epidemiology ; Humans ; New York City/epidemiology ; Schools
    Language English
    Publishing date 2021-02-11
    Publishing country Norway
    Document type Journal Article
    ZDB-ID 203487-6
    ISSN 1651-2227 ; 0365-1436 ; 0803-5253
    ISSN (online) 1651-2227
    ISSN 0365-1436 ; 0803-5253
    DOI 10.1111/apa.15786
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Coronavirus disease 2019 prevalence rates in reopened private schools in New York City: Impact of diagnostic methods.

    Smith-Norowitz, Tamar A / Kohlhoff, Stephan / Hammerschlag, Margaret R

    Acta paediatrica (Oslo, Norway : 1992)

    2021  Volume 110, Issue 8, Page(s) 2382–2384

    MeSH term(s) COVID-19 ; Humans ; New York City/epidemiology ; Prevalence ; SARS-CoV-2 ; Schools
    Language English
    Publishing date 2021-04-02
    Publishing country Norway
    Document type Journal Article
    ZDB-ID 203487-6
    ISSN 1651-2227 ; 0365-1436 ; 0803-5253
    ISSN (online) 1651-2227
    ISSN 0365-1436 ; 0803-5253
    DOI 10.1111/apa.15853
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  8. Article: Treatment of Methicillin-Resistant Staphylococcus aureus (MRSA) Infections in Children: a Reappraisal of Vancomycin.

    Sharma, Roopali / Hammerschlag, Margaret R

    Current infectious disease reports

    2019  Volume 21, Issue 10, Page(s) 37

    Abstract: Purpose of review: In the last 50 years, vancomycin has been the agent of choice to treat infections due to methicillin-resistant Staphylococcus aureus (MRSA). However, vancomycin treatment failure is not uncommon, even when MRSA strains are fully ... ...

    Abstract Purpose of review: In the last 50 years, vancomycin has been the agent of choice to treat infections due to methicillin-resistant Staphylococcus aureus (MRSA). However, vancomycin treatment failure is not uncommon, even when MRSA strains are fully susceptible to vancomycin. Treatment with vancomycin requires careful monitoring of drug levels as there is a potential for nephrotoxicity. Resistance to clindamycin is not infrequent, which also limits therapeutic options for treating infections due to MRSA in children. This paper reviews the current data on pharmacokinetics and pharmacodynamics and clinical efficacy of vancomycin in children.
    Recent findings: Resistance to vancomycin in MRSA (MIC >2 mg/L) is infrequent; there is increasing evidence in the literature that vancomycin maybe ineffective against increasing proportion of isolates with MICs between 1 and 2 mg/L. Recent studies and meta-analyses have demonstrated that strains with high vancomycin MICs are associated with poor outcomes especially in patients with bacteremia and deep tissue infections due to MRSA. This gradual increase in vancomycin MIC has been reported as MIC creep or vancomycin heteroresistance. Patients infected with MRSA isolates that exhibit MIC creep experience poorer clinical outcomes, including delayed treatment response, increased mortality, increase rate of relapse, and extended hospitalization. There are limited data to guide vancomycin dosing in children with MRSA. Although the vancomycin area under the curve AUC
    Language English
    Publishing date 2019-09-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2019948-X
    ISSN 1534-3146 ; 1523-3847
    ISSN (online) 1534-3146
    ISSN 1523-3847
    DOI 10.1007/s11908-019-0695-4
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  9. Article ; Online: Treatment options for neonatal infections in the post-cefotaxime era.

    Franco, Susannah / Rampersad, Daniel / Mesa, Daniel / Hammerschlag, Margaret R

    Expert review of anti-infective therapy

    2022  Volume 20, Issue 10, Page(s) 1253–1259

    Abstract: Introduction: Cefotaxime has been used for the management of neonatal infections since the 1990s for suspected meningitis and to mitigate gentamicin-associated renal injury. Its shortage in 2015 and subsequent removal from the U.S. pharmaceutical market ...

    Abstract Introduction: Cefotaxime has been used for the management of neonatal infections since the 1990s for suspected meningitis and to mitigate gentamicin-associated renal injury. Its shortage in 2015 and subsequent removal from the U.S. pharmaceutical market forced providers to consider alternatives. Ceftriaxone, a cephalosporin with an identical antibacterial spectrum of activity to cefotaxime, is contraindicated in neonates due to its risk of biliary pseudolithiasis. Ceftazidime was recommended as an alternative by the American Academy of Pediatrics but is inequivalent.
    Areas covered: This article addresses indications for cephalosporin use and considerations when selecting an alternative to cefotaxime. Differences among cefotaxime, ceftriaxone, ceftazidime, and cefepime are discussed and compared to the standard-of-care presumptive regimen, ampicillin, and gentamicin. The authors consider the data behind the neonatal contraindication to ceftriaxone and provide recommendations for their application to practice.
    Expert opinion: The data against ceftriaxone use in neonates remain poor, particularly in the context of the cefotaxime shortage and lack of an equivalent alternative. Ceftriaxone could be considered in low-risk neonates without hyperbilirubinemia or exposure to calcium-containing fluids on a case-by-case basis. Ceftazidime monotherapy for presumptive management of neonatal infections is inappropriate; cefepime should be more frequently utilized in neonates who are poor candidates for ceftriaxone.
    MeSH term(s) Ampicillin ; Anti-Bacterial Agents/adverse effects ; Calcium ; Cefepime ; Cefotaxime ; Ceftazidime ; Ceftriaxone/adverse effects ; Cephalosporins/adverse effects ; Communicable Diseases/drug therapy ; Gentamicins/toxicity ; Humans ; Infant, Newborn ; Infant, Newborn, Diseases/drug therapy ; Microbial Sensitivity Tests
    Chemical Substances Anti-Bacterial Agents ; Cephalosporins ; Gentamicins ; Ceftriaxone (75J73V1629) ; Ampicillin (7C782967RD) ; Cefepime (807PW4VQE3) ; Ceftazidime (9M416Z9QNR) ; Cefotaxime (N2GI8B1GK7) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2022-08-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2181279-2
    ISSN 1744-8336 ; 1478-7210
    ISSN (online) 1744-8336
    ISSN 1478-7210
    DOI 10.1080/14787210.2022.2110069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Perinatally Acquired Chlamydia trachomatis Infection in Children.

    Banniettis, Natalie / Hammerschlag, Margaret R

    The Pediatric infectious disease journal

    2018  Volume 37, Issue 8, Page(s) 835

    MeSH term(s) Child ; Chlamydia Infections ; Chlamydia trachomatis ; Humans ; Prognosis
    Language English
    Publishing date 2018-07-23
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000002075
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