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  1. Article ; Online: To the Editor.

    Rampil, Ira J

    Anesthesia and analgesia

    2023  Volume 136, Issue 5, Page(s) e21–e22

    Language English
    Publishing date 2023-04-14
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000006430
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: Fundamentals of neuroanesthesia

    Ruskin, Keith / Rosenbaum, Stanley H. / Rampil, Ira J.

    a physiologic approach to clinical practice

    2014  

    Author's details ed. by Keith J. Ruskin ; Stanley H. Rosenbaum ; Ira J. Rampil
    Keywords Anesthesia ; Neurosurgical Procedures
    Language English
    Size XIII, 370 S. : Ill.
    Publisher Oxford Univ. Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT018134551
    ISBN 978-0-19-975598-1 ; 0-19-975598-1
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2014 A 254 available for loan (reading room) Lesesaal EG

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  3. Article ; Online: Where is the impact?

    Rampil, Ira J / Rampil, Linda S

    Anesthesiology

    2010  Volume 113, Issue 4, Page(s) 995; author reply 995–6

    MeSH term(s) Critical Care ; Humans ; Intensive Care Units/statistics & numerical data ; Monitoring, Physiologic/methods ; Oximetry ; Oxygen/blood ; Patient Transfer ; Postoperative Period
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2010-10
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 269-0
    ISSN 1528-1175 ; 0003-3022
    ISSN (online) 1528-1175
    ISSN 0003-3022
    DOI 10.1097/ALN.0b013e3181eff877
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Monitoring depth of anesthesia.

    Rampil, I J

    Current opinion in anaesthesiology

    2006  Volume 14, Issue 6, Page(s) 649–653

    Abstract: Devices which monitor some aspect of anesthetic drug effects have evolved in the past few years into imperfect, but very useful, clinical tools. With appropriate respect for their limitations these monitors can be used to reduce anesthetic drug ... ...

    Abstract Devices which monitor some aspect of anesthetic drug effects have evolved in the past few years into imperfect, but very useful, clinical tools. With appropriate respect for their limitations these monitors can be used to reduce anesthetic drug utilization and turnover time. The intriguing hypothesis that such monitors will reduce the risk of intraoperative awareness is currently under test.
    Language English
    Publishing date 2006-09-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645203-6
    ISSN 1473-6500 ; 0952-7907
    ISSN (online) 1473-6500
    ISSN 0952-7907
    DOI 10.1097/00001503-200112000-00009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Bispectral Index for sleep screening: it is time to move on.

    Carozzi, C / Rampil, I J

    Minerva anestesiologica

    2011  Volume 77, Issue 5, Page(s) 485–487

    MeSH term(s) Consciousness Monitors ; Electroencephalography ; Humans ; Monitoring, Intraoperative ; Polysomnography ; Sleep/drug effects ; Sleep/physiology ; Sleep Deprivation ; Sleep, REM/drug effects
    Language English
    Publishing date 2011-05
    Publishing country Italy
    Document type Comment ; Editorial
    ZDB-ID 123584-9
    ISSN 1827-1596 ; 0026-4717 ; 0375-9393
    ISSN (online) 1827-1596
    ISSN 0026-4717 ; 0375-9393
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    Zs.MO 192: Show issues

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  6. Article: Dynamic response to volatile anesthetics has been examined before.

    Rampil, I J

    Anesthesiology

    2000  Volume 92, Issue 2, Page(s) 627–628

    MeSH term(s) Anesthetics, Inhalation/pharmacology ; Electroencephalography/drug effects ; Humans
    Chemical Substances Anesthetics, Inhalation
    Language English
    Publishing date 2000-02
    Publishing country United States
    Document type Letter
    ZDB-ID 269-0
    ISSN 0003-3022
    ISSN 0003-3022
    DOI 10.1097/00000542-200002000-00058
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  7. Article: Medical information on the Internet.

    Rampil, I J

    Anesthesiology

    1998  Volume 89, Issue 5, Page(s) 1233–1245

    MeSH term(s) Anesthesiology ; Information Services ; Internet ; MEDLINE ; Publishing
    Language English
    Publishing date 1998-11
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 269-0
    ISSN 0003-3022
    ISSN 0003-3022
    DOI 10.1097/00000542-199811000-00025
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  8. Article: A primer for EEG signal processing in anesthesia.

    Rampil, I J

    Anesthesiology

    1998  Volume 89, Issue 4, Page(s) 980–1002

    MeSH term(s) Anesthesiology/methods ; Electroencephalography/methods ; Humans ; Signal Processing, Computer-Assisted
    Language English
    Publishing date 1998-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 269-0
    ISSN 0003-3022
    ISSN 0003-3022
    DOI 10.1097/00000542-199810000-00023
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  9. Article ; Online: Spectral entropy predicts auditory recall in volunteers.

    Moller, Daryn H / Rampil, Ira J

    Anesthesia and analgesia

    2008  Volume 106, Issue 3, Page(s) 873–9, table of contents

    Abstract: Background: From a patient's perspective, intraoperative amnesia is an essential component of general anesthesia. Without specific strategies to reduce recall, its incidence is approximately 0.2% in the general surgical population and may be higher in ... ...

    Abstract Background: From a patient's perspective, intraoperative amnesia is an essential component of general anesthesia. Without specific strategies to reduce recall, its incidence is approximately 0.2% in the general surgical population and may be higher in certain subpopulations. We sought to test the validity for predicting recall of a new spectral entropy-based clinical electroencephalogram monitor.
    Methods: We studied 16 volunteers in an unblinded crossover design to assess the correlation of entropy values with behavioral end points during sedation with either propofol or sevoflurane. The end points we considered included word recall, and motor response to verbal command. We also examined the stimulatory effect of verbal commands on electroencephalogram entropy. Logistic regression, receiver operating characteristics, and prediction probability were used to analyze the data.
    Results: Both State Entropy and Response Entropy were closely correlated with both behavioral end points. The prediction probability of these parameters under a variety of conditions ranged from 0.85 to 0.96. Verbal command to move increased entropy in a dose and drug-dependent fashion.
    Conclusions: Entropy parameters in this group of young, healthy volunteers appear to be reliable predictors of recall. These results justify extending these studies to additional anesthetics and to surgical patients.
    MeSH term(s) Adult ; Amnesia/chemically induced ; Amnesia/diagnosis ; Amnesia/physiopathology ; Amnesia/psychology ; Auditory Perception/drug effects ; Cross-Over Studies ; Dose-Response Relationship, Drug ; Drug Administration Schedule ; Electroencephalography/instrumentation ; Electroencephalography/methods ; Female ; Humans ; Hypnotics and Sedatives/administration & dosage ; Hypnotics and Sedatives/adverse effects ; Logistic Models ; Male ; Mental Recall/drug effects ; Methyl Ethers/administration & dosage ; Methyl Ethers/adverse effects ; Models, Statistical ; Motor Skills/drug effects ; Predictive Value of Tests ; Propofol/administration & dosage ; Propofol/adverse effects ; ROC Curve ; Reference Values ; Reproducibility of Results ; Signal Processing, Computer-Assisted ; Time Factors
    Chemical Substances Hypnotics and Sedatives ; Methyl Ethers ; sevoflurane (38LVP0K73A) ; Propofol (YI7VU623SF)
    Language English
    Publishing date 2008-03
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ane.0b013e318163201d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Anesthetic potency is not altered after hypothermic spinal cord transection in rats.

    Rampil, I J

    Anesthesiology

    1994  Volume 80, Issue 3, Page(s) 606–610

    Abstract: Background: In essence, the clinical goal of general anesthesia is to produce a state of unresponsiveness and amnesia. These endpoints are commonly achieved with drugs like isoflurane, but the sites and mechanisms by which these specific endpoints are ... ...

    Abstract Background: In essence, the clinical goal of general anesthesia is to produce a state of unresponsiveness and amnesia. These endpoints are commonly achieved with drugs like isoflurane, but the sites and mechanisms by which these specific endpoints are achieved remain unknown. Blocking the somatic motor response to painful stimuli is widely used as an indicator of anesthetic adequacy, and the concentration of anesthetic agent (minimum alveolar concentration [MAC]) required to achieve this unresponsiveness is the benchmark of anesthetic potency. Recent work has demonstrated that precollicular decerebration does not alter MAC in rats, suggesting that the forebrain is not a major site of action of isoflurane in blocking motor responses. The brain stem contains systems that modulate pain processing in the spinal cord. The current study was undertaken to assess the relative roles of the brain stem and spinal cord as sites of anesthetic action in blocking somatic responsiveness.
    Methods: In seven rats, anesthesia was induced and maintained with isoflurane in oxygen. MAC was determined by observing the response to tail clamp and fore- and hind limb toe pinch at three times: after intubation, after cervical laminectomy, and after staged hypothermic spinal cord transection.
    Results: MAC determined by tail clamp did not change during the protocol (1.28 +/- 0.08% [mean +/- standard deviation] baseline vs. 1.25 +/- 0.18% postlaminectomy vs. 1.03 +/- 0.40% posttransection). In one animal, the MAC value decreased from a prelesion value of 1.2% to 0.25%, accounting for most of the variance in the postlesion mean; the MAC value as determined by withdrawal to rear paw pinch was unchanged from its prelesion value in this animal. The MAC values as determined by toe pinch in all animals remained unchanged after spinal transection of the lesion both rostrally and caudally.
    Conclusions: Somatic motor responsiveness and its sensitivity to isoflurane appeared to be unaltered despite acute loss of descending cortical and bulbar controls. This observation suggests that the site of anesthetic inhibition of motor response may be in the spinal cord.
    MeSH term(s) Administration, Inhalation ; Anesthesia, General ; Anesthetics/administration & dosage ; Anesthetics/pharmacokinetics ; Anesthetics/pharmacology ; Animals ; Brain Stem/drug effects ; Brain Stem/physiology ; Hypothermia, Induced ; Male ; Motor Activity/drug effects ; Pain/drug therapy ; Pulmonary Alveoli/metabolism ; Rats ; Rats, Sprague-Dawley ; Spinal Cord/drug effects ; Spinal Cord/physiology ; Spinal Cord/surgery
    Chemical Substances Anesthetics
    Language English
    Publishing date 1994-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 269-0
    ISSN 0003-3022
    ISSN 0003-3022
    DOI 10.1097/00000542-199403000-00017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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