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  1. Book: Stroke and the neurosurgeon

    Hopkins, L. N. / Khalessi, Alexander A.

    (World neurosurgery ; 76,6, Suppl.)

    2011  

    Author's details guest ed.: L. Nelson Hopkins and Alexander A. Khalessi
    Series title World neurosurgery ; 76,6, Suppl.
    Collection
    Language English
    Size S90 S. : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT017166099
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 1159 -76,6,Suppl.- not available for loan Zeitschriften-Lesesaal

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  2. Article ; Online: Traumatic Brain Injuries After Falls From Height vs Falls at the US-Mexico Border Wall.

    Tenorio, Alexander / Brandel, Michael G / McCann, Carson P / Doucet, Jay J / Costantini, Todd W / Khalessi, Alexander A / Ciacci, Joseph D

    JAMA surgery

    2024  

    Language English
    Publishing date 2024-04-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701841-6
    ISSN 2168-6262 ; 2168-6254
    ISSN (online) 2168-6262
    ISSN 2168-6254
    DOI 10.1001/jamasurg.2024.0008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Safety of middle meningeal artery embolization for treatment of subdural hematoma: A nationwide propensity score matched analysis.

    McCann, Carson P / Brandel, Michael G / Wali, Arvin R / Steinberg, Jeffrey A / Pannell, J Scott / Santiago-Dieppa, David R / Khalessi, Alexander A

    Journal of cerebrovascular and endovascular neurosurgery

    2023  Volume 25, Issue 4, Page(s) 380–389

    Abstract: Objective: Middle meningeal artery embolization (MMAe) has burgeoned as a treatment for chronic subdural hematoma (cSDH). This study evaluates the safety and short-term outcomes of MMAe patients relative to traditional treatment approaches.: Methods: ...

    Abstract Objective: Middle meningeal artery embolization (MMAe) has burgeoned as a treatment for chronic subdural hematoma (cSDH). This study evaluates the safety and short-term outcomes of MMAe patients relative to traditional treatment approaches.
    Methods: In this retrospective large database study, adult patients in the National Inpatient Sample from 2012-2019 with a diagnosis of cSDH were identified. Cost of admission, length of stay (LOS), discharge disposition, and complications were analyzed. Propensity score matching (PSM) was utilized.
    Results: A total of 123,350 patients with cSDH were identified: 63,450 without intervention, 59,435 surgery only, 295 MMAe only, and 170 surgery plus MMAe. On PSM analysis, MMAe did not increase the risk of inpatient complications or prolong the length of stay compared to conservative management (p>0.05); MMAe had higher cost ($31,170 vs. $10,768, p<0.001) than conservative management, and a lower rate of nonroutine discharge (53.8% vs. 64.3%, p=0.024). Compared to surgery, MMAe had shorter LOS (5 vs. 7 days, p<0.001), and lower rates of neurological complications (2.7% vs. 7.1%, p=0.029) and nonroutine discharge (53.8% vs. 71.7%, p<0.001). There was no significant difference in cost (p>0.05).
    Conclusions: MMAe had similar LOS and decreased odds of adverse discharge with a modest cost increase compared to conservative management. There was no difference in inpatient complications. Compared to surgery, MMAe treatment was associated with decreased LOS and rates of neurological complications and nonroutine discharge. This nationwide analysis supports the safety of MMAe to treat cSDH.
    Language English
    Publishing date 2023-07-20
    Publishing country Korea (South)
    Document type Journal Article
    ISSN 2234-8565
    ISSN 2234-8565
    DOI 10.7461/jcen.2023.E2023.05.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Optimizing suction force in mechanical thrombectomy: Priming the aspiration tubing with air versus saline.

    Wali, Arvin R / Sindewald, Ryan W / Brandel, Michael G / Bravo, Javier / Steinberg, Jeffrey A / Pannell, J Scott / Khalessi, Alexander A / Santiago-Dieppa, David R

    Journal of cerebrovascular and endovascular neurosurgery

    2024  

    Abstract: Objective: We sought to investigate how priming the tube between air versus air mixed with saline ex vivo influenced suction force. We examined how priming the tube influenced peak suction force and time to achieve peak suction force between both ... ...

    Abstract Objective: We sought to investigate how priming the tube between air versus air mixed with saline ex vivo influenced suction force. We examined how priming the tube influenced peak suction force and time to achieve peak suction force between both modalities.
    Methods: Using a Dwyer Instruments (Dwyer Instruments Inc., Michigan City, IN, USA), INC Digitial Pressure Gauge, we were able to connect a .072 inch aspiration catheter to a rotating hemostatic valve and to aspiration tubing. We recorded suction force measured in negative inches of Mercury (inHg) over 10 iterations between having the aspiration tube primed with air alone versus air mixed with saline. A test was used to compare results between both modalities.
    Results: Priming the tube with air alone compared to air mixed with saline was found to have an increased average max suction force (-28.60 versus -28.20 in HG, p<0.01). We also identified a logarithmic curve of suction force across time in which time to maximal suction force was more prompt with air compared with air mixed with saline (13.8 seconds versus 21.60 seconds, p<0.01).
    Conclusions: Priming the tube with air compared to air mixed with saline suggests that not only is increased maximal suction force achieved, but also the time required to achieve maximal suction force is less. This data suggests against priming the aspiration tubing with saline and suggests that the first pass aspiration primed with air may have the greatest suction force.
    Language English
    Publishing date 2024-02-27
    Publishing country Korea (South)
    Document type Journal Article
    ISSN 2234-8565
    ISSN 2234-8565
    DOI 10.7461/jcen.2024.E2023.09.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Comment on Endovascular treatment of intracranial stenosis.

    Khalessi, Alexander A

    World neurosurgery

    2011  Volume 76, Issue 6 Suppl, Page(s) S71

    MeSH term(s) Brain Ischemia/surgery ; Endovascular Procedures/methods ; Humans
    Keywords covid19
    Language English
    Publishing date 2011-12
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2011.08.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1159: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Histology of the Porous Oculomotorius: Relevance to Anterior Skull Base Approaches.

    Rennert, Robert C / Goodwill, Vanessa / Steinberg, Jeffrey A / Fukushima, Takanori / Day, John D / Khalessi, Alexander A / Levy, Michael L

    Journal of neurological surgery. Part B, Skull base

    2022  Volume 84, Issue 3, Page(s) 210–216

    Abstract: ... ...

    Abstract Objective
    Language English
    Publishing date 2022-04-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2654269-9
    ISSN 2193-634X ; 2193-6331
    ISSN (online) 2193-634X
    ISSN 2193-6331
    DOI 10.1055/a-1780-4619
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    Zs.A 3425: Show issues Location:
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  7. Article ; Online: Stroke and the Neurosurgeon: supplement to WORLD NEUROSURGERY.

    Khalessi, Alexander A

    World neurosurgery

    2011  Volume 76, Issue 3-4, Page(s) 248–249

    MeSH term(s) Brain Ischemia/complications ; Brain Ischemia/surgery ; Cost of Illness ; Humans ; Neurology/trends ; Neurosurgery/trends ; Periodicals as Topic ; Stroke/epidemiology ; Stroke/etiology ; Stroke/surgery ; Stroke/therapy ; Thrombectomy ; Thrombolytic Therapy
    Language English
    Publishing date 2011-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2011.06.054
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1159: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  8. Article ; Online: Recognizing the varied pathogenesis of ischemic stroke, the ensuing section examines anatomical stroke etiologies of particular surgical interest in terms of secondary prevention. Prefaces.

    Khalessi, Alexander A

    World neurosurgery

    2011  Volume 76, Issue 6 Suppl, Page(s) S1–2

    MeSH term(s) Brain Ischemia/complications ; Brain Ischemia/diagnosis ; Brain Ischemia/surgery ; Cerebral Revascularization ; Humans ; Neurosurgery/trends ; Secondary Prevention ; Stroke/diagnosis ; Stroke/epidemiology ; Stroke/etiology ; Stroke/surgery ; Triage
    Language English
    Publishing date 2011-12
    Publishing country United States
    Document type Introductory Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2011.08.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1159: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: ARISE I Consensus Statement on the Management of Chronic Subdural Hematoma.

    Kan, Peter / Fiorella, David / Dabus, Guilherme / Samaniego, Edgar A / Lanzino, Giuseppe / Siddiqui, Adnan H / Chen, Huanwen / Khalessi, Alexander A / Pereira, Vitor Mendes / Fifi, Johanna T / Bain, Mark D / Colby, Geoffrey P / Wakhloo, Ajay K / Arthur, Adam S

    Stroke

    2024  Volume 55, Issue 5, Page(s) 1438–1448

    Abstract: ARISE (Aneurysm/AVM/cSDH Roundtable Discussion With Industry and Stroke Experts) organized a one-and-a-half day meeting and workshop and brought together representatives from academia, industry, and government to discuss the most promising approaches to ... ...

    Abstract ARISE (Aneurysm/AVM/cSDH Roundtable Discussion With Industry and Stroke Experts) organized a one-and-a-half day meeting and workshop and brought together representatives from academia, industry, and government to discuss the most promising approaches to improve outcomes for patients with chronic subdural hematoma (cSDH). The emerging role of middle meningeal artery embolization in clinical practice and the design of current and potential future trials were the primary focuses of discussion. Existing evidence for imaging, indications, agents, and techniques was reviewed, and areas of priority for study and key questions surrounding the development of new and existing treatments for cSDH were identified. Multiple randomized, controlled trials have met their primary efficacy end points, providing high-level evidence that middle meningeal artery embolization is a potent adjunctive therapy to the standard (surgical and nonsurgical) management of neurologically stable cSDH patients in terms of reducing rates of disease recurrence. Pooled data analyses following the formal conclusion and publication of these trials will form a robust foundation upon which guidelines can be strengthened for cSDH treatment modalities and optimal patient selection, as well as delineate future lines of investigation.
    MeSH term(s) Humans ; Hematoma, Subdural, Chronic/therapy ; Embolization, Therapeutic/methods ; Consensus ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2024-04-22
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Consensus Development Conference ; Review
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.123.044129
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 448: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  10. Article ; Online: Treatment of pediatric intracranial aneurysms: institutional case series and systematic literature review.

    Brandel, Michael G / Plonsker, Jillian H / Rennert, Robert C / Produturi, Gautam / Saripella, Megana / Wali, Arvin R / McCann, Carson / Ravindra, Vijay M / Santiago-Dieppa, David R / Pannell, J Scott / Steinberg, Jeffrey A / Khalessi, Alexander A / Levy, Michael L

    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

    2024  

    Abstract: Introduction: Pediatric intracranial aneurysms (IAs) are rare and have distinct clinical profiles compared to adult IAs. They differ in location, size, morphology, presentation, and treatment strategies. We present our experience with pediatric IAs over ...

    Abstract Introduction: Pediatric intracranial aneurysms (IAs) are rare and have distinct clinical profiles compared to adult IAs. They differ in location, size, morphology, presentation, and treatment strategies. We present our experience with pediatric IAs over an 18-year period using surgical and endovascular treatments and review the literature to identify commonalities in epidemiology, treatment, and outcomes.
    Methods: We identified all patients < 20 years old who underwent treatment for IAs at our institution between 2005 and 2020. Medical records and imaging were examined for demographic, clinical, and operative data. A systematic review was performed to identify studies reporting primary outcomes of surgical and endovascular treatment of pediatric IAs. Demographic information, aneurysm characteristics, treatment strategies, and outcomes were collected.
    Results: Thirty-three patients underwent treatment for 37 aneurysms over 18 years. The mean age was 11.4 years, ranging from one month to 19 years. There were 21 males (63.6%) and 12 females (36.4%), yielding a male: female ratio of 1.75:1. Twenty-six (70.3%) aneurysms arose from the anterior circulation and 11 (29.7%) arose from the posterior circulation. Aneurysmal rupture occurred in 19 (57.5%) patients, of which 8 (24.2%) were categorized as Hunt-Hess grades IV or V. Aneurysm recurrence or rerupture occurred in five (15.2%) patients, and 5 patients (15.2%) died due to sequelae of their aneurysms. Twenty-one patients (63.6%) had a good outcome (modified Rankin Scale score 0-2) on last follow up. The systematic literature review yielded 48 studies which included 1,482 total aneurysms (611 with endovascular treatment; 656 treated surgically; 215 treated conservatively). Mean aneurysm recurrence rates in the literature were 12.7% and 3.9% for endovascular and surgical treatment, respectively.
    Conclusions: Our study provides data on the natural history and longitudinal outcomes for children treated for IAs at a single institution, in addition to our treatment strategies for various aneurysmal morphologies. Despite the high proportion of patients presenting with rupture, good functional outcomes can be achieved for most patients.
    Language English
    Publishing date 2024-04-18
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 605988-0
    ISSN 1433-0350 ; 0302-2803 ; 0256-7040
    ISSN (online) 1433-0350
    ISSN 0302-2803 ; 0256-7040
    DOI 10.1007/s00381-024-06384-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2036: Show issues Location:
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