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  1. Article ; Online: Sex- and Ethnicity-related Differences in Pheochromocytoma/Paraganglioma.

    Turai, Peter Istvan / Igaz, Peter

    Journal of the Endocrine Society

    2024  Volume 8, Issue 6, Page(s) bvae070

    Language English
    Publishing date 2024-04-09
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2472-1972
    ISSN (online) 2472-1972
    DOI 10.1210/jendso/bvae070
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Thyroid Blocking Policy in Hungary and Clarification of Terminology in the Light of Recommendations by International Organisations.

    Turai, István

    Radiation protection dosimetry

    2016  Volume 171, Issue 1, Page(s) 57–60

    Abstract: The ambiguous terminology 'Iodine Prophylaxis' used for decades to provide iodine to the population for very different purposes as well as its replacement with 'Iodine Thyroid Blocking' is discussed and argued. Recommendations of international ... ...

    Abstract The ambiguous terminology 'Iodine Prophylaxis' used for decades to provide iodine to the population for very different purposes as well as its replacement with 'Iodine Thyroid Blocking' is discussed and argued. Recommendations of international organisations regarding the action level for Iodine Thyroid Blocking and their implementation in national regulations in a few Member States of the European Union, and particularly in Hungary, is presented and discussed.
    MeSH term(s) Disaster Planning/legislation & jurisprudence ; Disaster Planning/methods ; Europe ; European Union ; Guidelines as Topic ; Health Promotion ; Humans ; Hungary ; International Agencies ; International Cooperation ; Iodine/therapeutic use ; Iodine Radioisotopes/adverse effects ; Occupational Exposure/prevention & control ; Potassium Iodide/therapeutic use ; Radiation Injuries/prevention & control ; Tablets ; Thyroid Gland/radiation effects
    Chemical Substances Iodine Radioisotopes ; Tablets ; Potassium Iodide (1C4QK22F9J) ; Iodine (9679TC07X4)
    Language English
    Publishing date 2016-08-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 225912-6
    ISSN 1742-3406 ; 0144-8420
    ISSN (online) 1742-3406
    ISSN 0144-8420
    DOI 10.1093/rpd/ncw225
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online: Thyroid Blocking Policy in Hungary and Clarification of Terminology in the Light of Recommendations by International Organisations

    Turai, István

    2016  

    Abstract: Journal Article ... The ambiguous terminology 'Iodine Prophylaxis' used for decades to provide iodine to the population for very different purposes as well as its replacement with 'Iodine Thyroid Blocking' is discussed and argued. Recommendations of ... ...

    Abstract Journal Article

    The ambiguous terminology 'Iodine Prophylaxis' used for decades to provide iodine to the population for very different purposes as well as its replacement with 'Iodine Thyroid Blocking' is discussed and argued. Recommendations of international organisations regarding the action level for Iodine Thyroid Blocking and their implementation in national regulations in a few Member States of the European Union, and particularly in Hungary, is presented and discussed.
    Language English
    Publishing date 2016-08-29
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Exploratory Circular RNA Profiling in Adrenocortical Tumors.

    Turai, Péter István / Nyirő, Gábor / Borka, Katalin / Micsik, Tamás / Likó, István / Patócs, Attila / Igaz, Peter

    Cancers

    2022  Volume 14, Issue 17

    Abstract: Differentiation of adrenocortical adenoma (ACA) and carcinoma (ACC) is often challenging even in the histological analysis. Circular RNAs (circRNAs) belonging to the group of non-coding RNAs have been implicated as relevant factors in tumorigenesis. Our ... ...

    Abstract Differentiation of adrenocortical adenoma (ACA) and carcinoma (ACC) is often challenging even in the histological analysis. Circular RNAs (circRNAs) belonging to the group of non-coding RNAs have been implicated as relevant factors in tumorigenesis. Our aim was to explore circRNA expression profiles in adrenocortical tumors by next-generation sequencing followed by RT-qPCR validation. Archived FFPE (formalin-fixed, paraffin embedded) including 8 ACC, 8 ACA and 8 normal adrenal cortices (NAC) were used in the discovery cohort. For de novo and known circRNA expression profiling, a next-generation sequencing platform was used. CIRI2, CircExplorer2, AutoCirc bioinformatics tools were used for the discovery of circRNAs. The top five most differentially circRNAs were measured by RT-qPCR in an independent validation cohort (10 ACC, 8 ACA, 8 NAC). In silico predicted, interacting microRNAs potentially sponged by differentially expressed circRNAs were studied by individual RT-qPCR assays. We focused on overexpressed circRNAs here. Significantly differentially expressed circRNAs have been revealed between the cohorts by NGS. Only
    Language English
    Publishing date 2022-09-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers14174313
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  5. Article ; Online: MicroRNAs and Adrenocortical Tumors: Where do we Stand on Primary Aldosteronism?

    Tömböl, Zsófia / Turai, Péter István / Decmann, Ábel / Igaz, Peter

    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme

    2020  Volume 52, Issue 6, Page(s) 394–403

    Abstract: MicroRNAs, the endogenous mediators of RNA interference, interact with the renin-angiotensin-aldosterone system, regulate aldosterone secretion and aldosterone effects. Some novel data show that the expression of some microRNAs is altered in primary ... ...

    Abstract MicroRNAs, the endogenous mediators of RNA interference, interact with the renin-angiotensin-aldosterone system, regulate aldosterone secretion and aldosterone effects. Some novel data show that the expression of some microRNAs is altered in primary aldosteronism, and some of these appear to have pathogenic relevance, as well. Differences in the circulating microRNA expression profiles between the two major forms of primary aldosteronism, unilateral aldosterone-producing adenoma and bilateral adrenal hyperplasia have also been shown. Here, we present a brief synopsis of these findings focusing on the potential relevance of microRNA in primary aldosteronism.
    MeSH term(s) Adrenal Cortex Neoplasms/complications ; Adrenal Cortex Neoplasms/genetics ; Adrenal Cortex Neoplasms/metabolism ; Adrenocortical Adenoma/complications ; Adrenocortical Adenoma/genetics ; Adrenocortical Adenoma/metabolism ; Aldosterone/metabolism ; Humans ; Hyperaldosteronism/genetics ; Hyperaldosteronism/metabolism ; Hypertension/etiology ; Hypertension/genetics ; Hypertension/metabolism ; MicroRNAs/genetics ; MicroRNAs/physiology
    Chemical Substances MicroRNAs ; Aldosterone (4964P6T9RB)
    Language English
    Publishing date 2020-03-13
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 80125-2
    ISSN 1439-4286 ; 0018-5043
    ISSN (online) 1439-4286
    ISSN 0018-5043
    DOI 10.1055/a-1116-2366
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 681: Show issues Location:
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  6. Article: MicroRNAs, Long Non-Coding RNAs, and Circular RNAs: Potential Biomarkers and Therapeutic Targets in Pheochromocytoma/Paraganglioma.

    Turai, Peter Istvan / Nyírő, Gábor / Butz, Henriett / Patócs, Attila / Igaz, Peter

    Cancers

    2021  Volume 13, Issue 7

    Abstract: Around 40% of pheochromocytomas/paragangliomas (PPGL) harbor germline mutations, representing the highest heritability among human tumors. All PPGL have metastatic potential, but metastatic PPGL is overall rare. There is no available molecular marker for ...

    Abstract Around 40% of pheochromocytomas/paragangliomas (PPGL) harbor germline mutations, representing the highest heritability among human tumors. All PPGL have metastatic potential, but metastatic PPGL is overall rare. There is no available molecular marker for the metastatic potential of these tumors, and the diagnosis of metastatic PPGL can only be established if metastases are found at "extra-chromaffin" sites. In the era of precision medicine with individually targeted therapies and advanced care of patients, the treatment options for metastatic pheochromocytoma/paraganglioma are still limited. With this review we would like to nurture the idea of the quest for non-coding ribonucleic acids as an area to be further investigated in tumor biology. Non-coding RNA molecules encompassing microRNAs, long non-coding RNAs, and circular RNAs have been implicated in the pathogenesis of various tumors, and were also proposed as valuable diagnostic, prognostic factors, and even potential treatment targets. Given the fact that the pathogenesis of tumors including pheochromocytomas/paragangliomas is linked to epigenetic dysregulation, it is reasonable to conduct studies related to their epigenetic expression profiles and in this brief review we present a synopsis of currently available findings on the relevance of these molecules in these tumors highlighting their diagnostic potential.
    Language English
    Publishing date 2021-03-26
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers13071522
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  7. Article ; Online: Realizing the European Network of Biodosimetry (RENEB) - concluding remarks.

    Lloyd, David / Turai, István / Voisin, Philippe

    International journal of radiation biology

    2017  Volume 93, Issue 1, Page(s) 142–144

    Language English
    Publishing date 2017-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 3065-x
    ISSN 1362-3095 ; 0020-7616 ; 0955-3002
    ISSN (online) 1362-3095
    ISSN 0020-7616 ; 0955-3002
    DOI 10.1080/09553002.2016.1178866
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    Ue I Zs.280: Show issues Location:
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  8. Article: Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis.

    Decmann, Abel / Perge, Pál / Turai, Peter Istvan / Patócs, Attila / Igaz, Peter

    Cancers

    2020  Volume 12, Issue 2

    Abstract: Non-coding RNA molecules including microRNAs and long non-coding RNAs (lncRNA) have been implicated in the pathogenesis of several tumors and numerous data support their applicability in diagnosis as well. Despite recent advances, the pathogenesis of ... ...

    Abstract Non-coding RNA molecules including microRNAs and long non-coding RNAs (lncRNA) have been implicated in the pathogenesis of several tumors and numerous data support their applicability in diagnosis as well. Despite recent advances, the pathogenesis of adrenocortical cancer still remains elusive and there are no reliable blood-borne markers of adrenocortical malignancy, either. Several findings show the potential applicability of microRNAs as biomarkers of malignancy and prognosis, and there are some data on lncRNA as well. In this review, we present a synopsis on the potential relevance of non-coding RNA molecules in adrenocortical pathogenesis and their applicability in diagnosis from tissue and blood.
    Language English
    Publishing date 2020-02-17
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers12020461
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  9. Article ; Online: Delayed-onset infections after lower third molar surgery: a Hungarian case-control study.

    Kaposvári, István / Körmöczi, Kinga / Csurgay, Kata / Horváth, Ferenc / Ashourioun, Amir Hossein / Buglyó, Alida / Turai, Adrienn Réka / Joób-Fancsaly, Árpád

    Oral surgery, oral medicine, oral pathology and oral radiology

    2021  Volume 132, Issue 6, Page(s) 641–647

    Abstract: Objective: Delayed-onset infection is defined as infectious swelling and trismus accompanied by pain or the presence of suppuration starting approximately 30 days after surgery. This study aimed to describe the occurrence and potential predisposing ... ...

    Abstract Objective: Delayed-onset infection is defined as infectious swelling and trismus accompanied by pain or the presence of suppuration starting approximately 30 days after surgery. This study aimed to describe the occurrence and potential predisposing factors of delayed-onset infection.
    Study design: A retrospective case-control study of 223 lower third molar surgeries was performed. Participants were selected from among 1102 outpatients who underwent surgery between January 2013 and June 2018 at Semmelweis University. The inclusion criterion for the case group was inflammation of the operated area after suture removal. Patients in the control group were healthy nonsmokers <26 years old who healed without complication. Statistical analysis was performed using the Shapiro-Wilk test, the Mann-Whitney U test, and Fisher's exact test.
    Results: Complications occurred only in patients <26 years old approximately 29.5 days after surgery. A significantly higher risk was observed for younger age, total soft tissue coverage, deeper impaction, lower Nolla stage (P < .001), mesioangular direction (P = .002), and full bone coverage (P < .05). Distal space was inversely correlated with complications (P < .001).
    Conclusions: Lower Nolla stage, total soft tissue coverage, lack of distal space, deeper impaction, or mesioangular tilt may promote delayed-onset infection. Follow-up of at-risk patients and the maintenance of oral hygiene are recommended.
    MeSH term(s) Adult ; Case-Control Studies ; Humans ; Hungary ; Molar, Third/surgery ; Pain, Postoperative ; Retrospective Studies ; Tooth Extraction/adverse effects ; Tooth, Impacted/complications ; Tooth, Impacted/surgery ; Trismus/etiology
    Language English
    Publishing date 2021-04-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2650843-6
    ISSN 2212-4411 ; 2212-4403
    ISSN (online) 2212-4411
    ISSN 2212-4403
    DOI 10.1016/j.oooo.2021.04.052
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    Ul III Zs.121: Show issues Location:
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  10. Article: [No title information]

    Tömböl, Zsófia / Turai, Péter István / Decmann, Ábel / Igaz, Peter

    Hormone and Metabolic Research

    (Progress in Primary Aldosteronism)

    2020  Volume 52, Issue 06, Page(s) 394–403

    Abstract: MicroRNAs, the endogenous mediators of RNA interference, interact with the renin-angiotensin-aldosterone system, regulate aldosterone secretion and aldosterone effects. Some novel data show that the expression of ... ...

    Series title Progress in Primary Aldosteronism
    Abstract MicroRNAs, the endogenous mediators of RNA interference, interact with the renin-angiotensin-aldosterone system, regulate aldosterone secretion and aldosterone effects. Some novel data show that the expression of some microRNAs is altered in primary aldosteronism, and some of these appear to have pathogenic relevance, as well. Differences in the circulating microRNA expression profiles between the two major forms of primary aldosteronism, unilateral aldosterone-producing adenoma and bilateral adrenal hyperplasia have also been shown. Here, we present a brief synopsis of these findings focusing on the potential relevance of microRNA in primary aldosteronism.
    Keywords primary aldosteronism ; microRNA ; target gene ; pathogenesis ; biomarker
    Language English
    Publishing date 2020-03-13
    Publisher © Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 80125-2
    ISSN 1439-4286 ; 0018-5043
    ISSN (online) 1439-4286
    ISSN 0018-5043
    DOI 10.1055/a-1116-2366
    Database Thieme publisher's database

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