LIVIVO - Search results -

Search results

Result 1 - 10 of total 46

Search options

Book ; Online: Jellyfish and Polyps : Cnidarians as Sustainable Resources for Biotechnological Applications and Bioprospecting

Leone, Antonella / Mariottini, Gian Luigi / Piraino, Stefano

2020

Keywords	Technology: general issues ; cnidarian ; sea anemone ; proteins ; toxins ; two-dimensional gel electrophoresis ; MALDI-TOF/TOF ; shotgun proteomic ; Zoanthidea ; holo-transcriptome ; cnidarian transcriptome ; marine enzyme ; marine biocatalyst ; marine biotechnology ; pharmaceutical biotechnology ; anthozoa ; microbial communities ; cnidarian holobiont ; zooxanthellae ; bleaching ; antibacterial activity ; jellyfish ; Aurelia coerulea ; mucus ; proteomics ; metabolomics ; cnidarians ; gelatinous zooplankton ; bioprospecting ; novel foods ; transcriptomics ; bio-prospecting ; computational biology ; neurotoxins ; NMR spectroscopy ; biochemical characterization ; jellyfish blooms ; Cnidaria ; Ctenophora ; biodiversity ; bioactive compounds ; blue biotechnology ; invertebrate proteins ; biological activity ; antioxidants ; collagen ; pepsin hydrolysis ; collagenase hydrolysis ; oxidative stress ; keratinocytes ; cytotoxicity ; Easter Island ; Actinobacteria ; anthraquinones ; symbionts ; marine invertebrates ; spectroscopy ; chromatography ; Pelagia noctiluca ; Mediterranean jellyfish ; chemical characterization ; aquafeed and food supplements ; sustainable fishing
Size	1 electronic resource (230 pages)
Publisher	MDPI - Multidisciplinary Digital Publishing Institute
Publishing place	Basel, Switzerland
Document type	Book ; Online
Note	English ; Open Access
HBZ-ID	HT021046974
ISBN	9783039432097 ; 3039432095
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Natural Compounds and Drug Discovery: Can Cnidarian Venom Play a Role?

Mariottini, Gian Luigi / Grice, Irwin Darren

Central nervous system agents in medicinal chemistry

2019 Volume 19, Issue 2, Page(s) 114–118

Abstract: Natural compounds extracted from organisms and microorganisms are an important resource for the development of drugs and bioactive molecules. Many such compounds have made valuable contributions in diverse fields such as human health, pharmaceutics and ... ...

Abstract	Natural compounds extracted from organisms and microorganisms are an important resource for the development of drugs and bioactive molecules. Many such compounds have made valuable contributions in diverse fields such as human health, pharmaceutics and industrial applications. Presently, however, research on investigating natural compounds from marine organisms is scarce. This is somewhat surprising considering that the marine environment makes a major contribution to Earth's ecosystems and consequently possesses a vast storehouse of diverse marine species. Interestingly, of the marine bioactive natural compounds identified to date, many are venoms, coming from Cnidarians (jellyfish, sea anemones, corals). Cnidarians are therefore particularly interesting marine species, producing important biological compounds that warrant further investigation for their development as possible therapeutic agents. From an experimental aspect, this review aims to emphasize and update the current scientific knowledge reported on selected biological activity (antiinflammatory, antimicrobial, antitumoral, anticoagulant, along with several less studied effects) of Cnidarian venoms/extracts, highlighting potential aspects for ongoing research towards their utilization in human therapeutic approaches.
MeSH term(s)	Animals ; Biological Factors/isolation & purification ; Biological Factors/therapeutic use ; Biological Products ; Cnidarian Venoms/isolation & purification ; Cnidarian Venoms/therapeutic use ; Drug Discovery/methods ; Drug Discovery/trends ; Humans ; Neoplasms/drug therapy
Chemical Substances	Biological Factors ; Biological Products ; Cnidarian Venoms
Language	English
Publishing date	2019-03-02
Publishing country	United Arab Emirates
Document type	Journal Article ; Review
ZDB-ID	2227560-5
ISSN	1875-6166 ; 1871-5249
ISSN (online)	1875-6166
ISSN	1871-5249
DOI	10.2174/1871524919666190227234834
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5594: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Kearns-Sayre syndrome with optic nerve atrophy phenotype

Agostino Berio / Gian Luigi Mariottini / Marco Frascio / Attilia Piazzi

Journal of Biological Research (2022)

A possible biological and clinical concurrence of two mutations?

2022

Abstract: The authors report about the association of progressive external ophthalmoplegia, atypical pigmentary retinopathy, ataxia phenotype with onset in first months of life (Kearns-Sayre syndrome) and with optic nerve atrophy and deafness. The localization of ... ...

Abstract	The authors report about the association of progressive external ophthalmoplegia, atypical pigmentary retinopathy, ataxia phenotype with onset in first months of life (Kearns-Sayre syndrome) and with optic nerve atrophy and deafness. The localization of retinal lesions was coincident with that reported by multifunctional electroretinogram (mfERG) in OPA 1 mutation. The authors hypothesize that Kearns-Sayre mitochondrial mutation may be associated with OPA 1 missense mutation, with worsening of symptomatology, as occurs in the reported case. The prolonged rehabilitation and treatment with coenzyme Q10 for many years gave positive results, with amelioration of ophthalmoplegia, stopping of aggravation of retinal damage and optic nerve atrophy, maintaining of vision some meters away, possibility of socialization and proprioceptive ability amelioration.
Keywords	Chronic progressive external ophthalmoplegia ; Kearns-Sayre syndrome ; Coenzyme Q10 therapy ; optic nerve atrophy ; OPA 1 mutation ; coenzyme Q10 ; Biology (General) ; QH301-705.5
Subject code	616
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	PAGEPress Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: The Eureka! by Kary Mullis

Lorenzo Gallus / Marco Giammanco / Gian Luigi Mariottini

Journal of Biological Research, Vol 92, Iss

2020 Volume 2

Abstract: Not available. ...

Abstract	Not available.
Keywords	Biology (General) ; QH301-705.5
Language	English
Publishing date	2020-03-01T00:00:00Z
Publisher	PAGEPress Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Hemolytic venoms from marine cnidarian jellyfish - an overview.

Mariottini, Gian Luigi

Journal of venom research

2014 Volume 5, Page(s) 22–32

Abstract: Cnidarian jellyfish are viewed as an emergent problem in several coastal zones throughout the world. Recurrent outbreaks pose a serious threat to tourists and bathers, as well as to sea-workers, involving health and economical aspects. As a rule, ... ...

Abstract	Cnidarian jellyfish are viewed as an emergent problem in several coastal zones throughout the world. Recurrent outbreaks pose a serious threat to tourists and bathers, as well as to sea-workers, involving health and economical aspects. As a rule, cnidarian stinging as a consequence of nematocyst firing induces merely local symptoms but cardiovascular or neurological complications can also occur. Hemolysis is a frequent effect of cnidarian stinging; this dangerous condition is known to be caused by several venoms and can sometimes be lethal. At present, the bulk of data concerning hemolytic cnidarian venoms comes from the study of benthic species, such as sea anemones and soft corals, but hemolytic factors were found in venoms of several siphonophore, cubozoan and scyphozoan jellyfish, which are mainly involved in the envenomation of bathers and sea-workers. Therefore, the aim of this paper is to review the scientific literature concerning the hemolytic venoms from cnidarian jellyfish taking into consideration their importance in human pathology as well as health implications and possible therapeutic measures.
Language	English
Publishing date	2014-07-23
Publishing country	England
Document type	Journal Article ; Review
ISSN	2044-0324
ISSN	2044-0324
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Role of model organisms and nanocompounds in human health risk assessment.

Lopes, André Moreni / Dahms, Hans-Uwe / Converti, Attilio / Mariottini, Gian Luigi

Environmental monitoring and assessment

2021 Volume 193, Issue 5, Page(s) 285

Abstract: Safeguarding the environment is one of the most serious modern challenges, as increasing amounts of chemical compounds are produced and released into the environment, causing a serious threat to the future health of the Earth as well as organisms and ... ...

Abstract	Safeguarding the environment is one of the most serious modern challenges, as increasing amounts of chemical compounds are produced and released into the environment, causing a serious threat to the future health of the Earth as well as organisms and humans on a global scale. Ecotoxicology is an integrative science involving different physical, chemical, biological, and social aspects concerned with the study of toxic effects caused by natural or synthetic pollutants on any constituents of ecosystems, including animals (including humans), plants, or microorganisms, in an integral context. In recent decades, this science has undergone considerable development by addressing environmental risk assessments through the biomonitoring of indicator species using biomarkers, model organisms, and nanocompounds in toxicological assays. Since a single taxon cannot be representative of complex ecotoxicological effects and mechanisms of action of a chemical, the use of test batteries is widely accepted in ecotoxicology. Test batteries include properly chosen organisms that are easy to breed, adapt easily to laboratory conditions, and are representative of the environmental compartment under consideration. One of the main issues of toxicological and ecotoxicological research is to gain a deeper understanding of how data should be obtained through laboratory and field approaches using experimental models and how they could be extrapolated to humans. There is a tendency to replace animal tests with in vitro systems and to perform them according to standardized analytical methods and the rules of the so-called good laboratory practice (GLP). This paper aims to review this topic to stimulate both efforts to understand the toxicological and ecotoxicological properties of natural and synthetic chemicals and the possible use of such data for application to humans.
MeSH term(s)	Animals ; Biological Assay ; Ecosystem ; Ecotoxicology ; Environmental Monitoring ; Humans ; Risk Assessment ; Water Pollutants, Chemical/analysis
Chemical Substances	Water Pollutants, Chemical
Language	English
Publishing date	2021-04-20
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	782621-7
ISSN	1573-2959 ; 0167-6369
ISSN (online)	1573-2959
ISSN	0167-6369
DOI	10.1007/s10661-021-09066-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 5186: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Antimicrobials from Cnidarians. A New Perspective for Anti-Infective Therapy?

Mariottini, Gian Luigi / Grice, Irwin Darren

Marine drugs

2016 Volume 14, Issue 3

Abstract: The ability of microbes to counter the scientific and therapeutic advancements achieved during the second half of the twentieth century to provide effective disease treatments is currently a significant challenge for researchers in biology and medicine. ... ...

Abstract	The ability of microbes to counter the scientific and therapeutic advancements achieved during the second half of the twentieth century to provide effective disease treatments is currently a significant challenge for researchers in biology and medicine. The discovery of antibiotics, and the subsequent development of synthetic antimicrobial compounds, altered our therapeutic approach towards infectious diseases, and improved the quality and length of life for humans and other organisms. The current alarming rise in cases of antibiotic-resistance has forced biomedical researchers to explore new ways to recognize and/or produce new antimicrobials or to find other approaches for existing therapeutics. Aquatic organisms are known to be a source of compounds having the potential to play a role in fighting the battle against pathogenic microbes. In this connection, cnidarians occupy a pre-eminent role. Over the past few decades several studies have explored the antimicrobial/antibiotic properties of cnidarian extracts with the aim of isolating compounds possessing useful therapeutic features. This paper aims to review the existing data on this subject, taking into account the possible utilization of identified compounds.
MeSH term(s)	Animals ; Anti-Infective Agents/isolation & purification ; Anti-Infective Agents/pharmacology ; Cnidaria/chemistry ; Drug Design ; Drug Discovery/methods ; Drug Resistance, Microbial ; Humans
Chemical Substances	Anti-Infective Agents
Language	English
Publishing date	2016-03-08
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2175190-0
ISSN	1660-3397 ; 1660-3397
ISSN (online)	1660-3397
ISSN	1660-3397
DOI	10.3390/md14030048
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

Article ; Online: In memory of Prof. Massimo Cocchi, past president and honorary president of the Italian Society for Experimental Biology (Società Italiana di Biologia Sperimentale - SIBS)

Gian Luigi Mariottini / Nicolò Benfante / Maria Grazia Bridelli / Francesco Cappello / Caterina Faggio / Concetta Messina / Antonella Pantaleo / Emma Rabino Massa

Journal of Biological Research (2022)

2022

Abstract: Prof. Massimo Cocchi, one of the most experienced scientists in nutritional biochemistry, past and honorary President of the Italian Society for Experimental Biology (Società Italiana di Biologia Sperimentale), passed away on May 19th, 2022, in his house ...

Abstract	Prof. Massimo Cocchi, one of the most experienced scientists in nutritional biochemistry, past and honorary President of the Italian Society for Experimental Biology (Società Italiana di Biologia Sperimentale), passed away on May 19th, 2022, in his house in San Lazzaro di Savena (Bologna). He was a man of the highest value both from the scientific and from the human point of view. He was a landmark for a lot of students, as well as for his friends and colleagues who always appreciated his high moral standing and his immeasurable competence not only in the scientific field which was the subject of his work during all life, but also in many other fields of biology and medicine, so that anyone who met him could always receive a suggestion or a reliable scientific opinion. [.]
Keywords	Biology (General) ; QH301-705.5
Language	English
Publishing date	2022-11-01T00:00:00Z
Publisher	PAGEPress Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Role of model organisms and nanocompounds in human health risk assessment

Lopes, André Moreni / Dahms, Hans-Uwe / Converti, Attilio / Mariottini, Gian Luigi

Environmental monitoring and assessment. 2021 May, v. 193, no. 5

2021

Abstract	Safeguarding the environment is one of the most serious modern challenges, as increasing amounts of chemical compounds are produced and released into the environment, causing a serious threat to the future health of the Earth as well as organisms and humans on a global scale. Ecotoxicology is an integrative science involving different physical, chemical, biological, and social aspects concerned with the study of toxic effects caused by natural or synthetic pollutants on any constituents of ecosystems, including animals (including humans), plants, or microorganisms, in an integral context. In recent decades, this science has undergone considerable development by addressing environmental risk assessments through the biomonitoring of indicator species using biomarkers, model organisms, and nanocompounds in toxicological assays. Since a single taxon cannot be representative of complex ecotoxicological effects and mechanisms of action of a chemical, the use of test batteries is widely accepted in ecotoxicology. Test batteries include properly chosen organisms that are easy to breed, adapt easily to laboratory conditions, and are representative of the environmental compartment under consideration. One of the main issues of toxicological and ecotoxicological research is to gain a deeper understanding of how data should be obtained through laboratory and field approaches using experimental models and how they could be extrapolated to humans. There is a tendency to replace animal tests with in vitro systems and to perform them according to standardized analytical methods and the rules of the so-called good laboratory practice (GLP). This paper aims to review this topic to stimulate both efforts to understand the toxicological and ecotoxicological properties of natural and synthetic chemicals and the possible use of such data for application to humans.
Keywords	biomarkers ; ecotoxicology ; environmental monitoring ; good laboratory practices ; health effects assessments ; human health ; indicator species ; risk ; toxicity
Language	English
Dates of publication	2021-05
Size	p. 285.
Publishing place	Springer International Publishing
Document type	Article
Note	NAL-AP-2-clean ; Review
ZDB-ID	782621-7
ISSN	1573-2959 ; 0167-6369
ISSN (online)	1573-2959
ISSN	0167-6369
DOI	10.1007/s10661-021-09066-2
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 5186: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: The role of Cnidaria in drug discovery. A review on CNS implications and new perspectives.

Mariottini, Gian Luigi / Pane, Luigi

Recent patents on CNS drug discovery

2013 Volume 8, Issue 2, Page(s) 110–122

Abstract: Many organisms produce bioactive substances used in the production of drugs. In this context, Cnidaria occupy a major position; for this reason, research on new bioactive substances has focused upon them as an interesting target. As a matter of fact, ... ...

Abstract	Many organisms produce bioactive substances used in the production of drugs. In this context, Cnidaria occupy a major position; for this reason, research on new bioactive substances has focused upon them as an interesting target. As a matter of fact, substances and extracts able to fight human diseases have been found in cnidarians, several of which have been studied in laboratories using animal models or cell cultures and, at present, some are in the pre-clinical phase. This review aims to highlight the research on existing drugs or new drug candidates extracted from Cnidaria and the recent patents published in this field; furthermore, as many cnidarian venoms are known to have an impact on the CNS and on neuromuscular transmission, this review particularly considers the research concerning CNS drug discovery and pending patents.
MeSH term(s)	Animals ; Central Nervous System/drug effects ; Cnidarian Venoms/therapeutic use ; Cnidarian Venoms/toxicity ; Drug Discovery/methods ; Humans ; Ion Channels/drug effects ; Neurotoxins/pharmacology ; Patents as Topic ; Phospholipases A2/pharmacology
Chemical Substances	Cnidarian Venoms ; Ion Channels ; Neurotoxins ; Phospholipases A2 (EC 3.1.1.4)
Language	English
Publishing date	2013-05-27
Publishing country	United Arab Emirates
Document type	Journal Article ; Review
ZDB-ID	2253602-4
ISSN	2212-3954 ; 1574-8898
ISSN (online)	2212-3954
ISSN	1574-8898
DOI	10.2174/15748898113089990003
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6437: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito