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  1. Article ; Online: Hypnotherapy and IBS: Time to take control of the Asian gut.

    Siah, Kewin Tien Ho / Mahadeva, Sanjiv

    JGH open : an open access journal of gastroenterology and hepatology

    2022  Volume 6, Issue 7, Page(s) 445–446

    Language English
    Publishing date 2022-07-07
    Publishing country Australia
    Document type Editorial
    ISSN 2397-9070
    ISSN (online) 2397-9070
    DOI 10.1002/jgh3.12785
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Post-COVID-19 functional gastrointestinal disorders: Prepare for a GI aftershock.

    Siah, Kewin Tien Ho / Mahadeva, Sanjiv

    Journal of gastroenterology and hepatology

    2022  Volume 37, Issue 3, Page(s) 413–414

    MeSH term(s) COVID-19/complications ; COVID-19/epidemiology ; Gastrointestinal Diseases/epidemiology ; Gastrointestinal Diseases/virology ; Humans ; SARS-CoV-2
    Language English
    Publishing date 2022-03-08
    Publishing country Australia
    Document type Editorial
    ZDB-ID 632882-9
    ISSN 1440-1746 ; 0815-9319
    ISSN (online) 1440-1746
    ISSN 0815-9319
    DOI 10.1111/jgh.15776
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Acid inhibitors and allergy: comorbidity, causation and confusion.

    Siah, Kewin Tien Ho

    Nature communications

    2020  Volume 11, Issue 1, Page(s) 3950

    MeSH term(s) Comorbidity ; Confusion ; Gastric Acid ; Humans ; Hypersensitivity ; Medical Records
    Language English
    Publishing date 2020-08-07
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-020-17831-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Airborne allergen, allergy & atopic IBS.

    Siah, Kewin Tien Ho

    Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society

    2019  Volume 31, Issue 3, Page(s) e13517

    MeSH term(s) Allergens ; Humans ; Hypersensitivity ; Immunoglobulin E ; Irritable Bowel Syndrome ; Self Report
    Chemical Substances Allergens ; Immunoglobulin E (37341-29-0)
    Language English
    Publishing date 2019-02-22
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1186328-6
    ISSN 1365-2982 ; 1350-1925
    ISSN (online) 1365-2982
    ISSN 1350-1925
    DOI 10.1111/nmo.13517
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Insights and future prospects of traditional Chinese medicine in the treatment of functional dyspepsia.

    Zhang, Jiaqi / Chen, Ting / Wen, Yongtian / Siah, Kewin Tien Ho / Tang, Xudong

    Phytomedicine : international journal of phytotherapy and phytopharmacology

    2024  Volume 127, Page(s) 155481

    Abstract: Background: Functional dyspepsia (FD) is a prevalent and challenging gastrointestinal disorder. Conventional medicine often faces limitations in providing effective treatment for FD, thus indicating the need to explore alternative approaches. ... ...

    Abstract Background: Functional dyspepsia (FD) is a prevalent and challenging gastrointestinal disorder. Conventional medicine often faces limitations in providing effective treatment for FD, thus indicating the need to explore alternative approaches. Traditional Chinese medicine (TCM), which is rooted in ancient Chinese traditions and has evolved over thousands of years, offers a holistic approach to well-being. TCM incorporates herbal remedies, acupuncture, and other therapies while shaping the future of complementary and alternative medicine.
    Purpose: To review the existing literature on the current status and future prospects of using TCM to treat FD.
    Methods: We extensively searched the PubMed, Google Scholar, Embase, an China National Knowledge Internet databases from inception to May 31, 2023 to identify relevant literature. We also searched the reference lists of the included articles.
    Results: Clinical evidence-based research has explored the efficacy of TCM in treating FD. Recent research has illuminated the multifaceted mechanisms through which TCM interventions affect FD. TCM is a promising alternative, as it emphasizes a holistic approach and holds potential advantages in addressing the complex nature of FD.
    Conclusions: The integration of TCM and Western medicine offers a comprehensive approach to understanding and managing FD by bridging traditional wisdom with modern scientific understanding. This paper highlights the practical implications of this integration, the challenges to be addressed, and the potential for international collaboration to further elucidate the efficacy of TCM. However, continued research and dialog are needed to advance the modern development of TCM and to improve the quality of life of FD patients.
    MeSH term(s) Humans ; Drugs, Chinese Herbal/therapeutic use ; Dyspepsia/drug therapy ; Medicine, Chinese Traditional ; Phytotherapy ; Quality of Life
    Chemical Substances Drugs, Chinese Herbal
    Language English
    Publishing date 2024-02-24
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1205240-1
    ISSN 1618-095X ; 0944-7113
    ISSN (online) 1618-095X
    ISSN 0944-7113
    DOI 10.1016/j.phymed.2024.155481
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Acid inhibitors and allergy

    Kewin Tien Ho Siah

    Nature Communications, Vol 11, Iss 1, Pp 1-

    comorbidity, causation and confusion

    2020  Volume 2

    Keywords Science ; Q
    Language English
    Publishing date 2020-08-01T00:00:00Z
    Publisher Nature Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Acid inhibitors and allergy

    Kewin Tien Ho Siah

    Nature Communications, Vol 11, Iss 1, Pp 1-

    comorbidity, causation and confusion

    2020  Volume 2

    Keywords Science ; Q
    Language English
    Publishing date 2020-08-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Dyssynergic defecation: The not so hidden partner in constipation.

    Siah, Kewin Tien Ho

    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology

    2018  Volume 37, Issue 3, Page(s) 186–188

    MeSH term(s) Ataxia ; Biofeedback, Psychology ; Constipation ; Defecation ; Defecography ; Humans ; Manometry
    Language English
    Publishing date 2018-07-04
    Publishing country India
    Document type Editorial ; Comment
    ZDB-ID 632595-6
    ISSN 0975-0711 ; 0254-8860
    ISSN (online) 0975-0711
    ISSN 0254-8860
    DOI 10.1007/s12664-018-0866-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Involving patients in the process: Development of a constipation patient-reported outcome measure for symptoms and quality of life.

    Lee, V Vien / Lau, Ni Yin / Blasiak, Agata / Siah, Kewin Tien Ho / Ho, Dean

    Computational and structural biotechnology journal

    2023  Volume 22, Page(s) 41–49

    Abstract: Objective: Patient-reported outcome measures (PROMs) are useful standardized tools to measure current patient health status and well-being. While there are existing constipation-related PROMs, the majority of PROMs were not developed with adequate ... ...

    Abstract Objective: Patient-reported outcome measures (PROMs) are useful standardized tools to measure current patient health status and well-being. While there are existing constipation-related PROMs, the majority of PROMs were not developed with adequate patient involvement and few examined content validity. Accordingly, the current study aimed to develop a constipation PROM with multiple phases of patient and clinician involvement.
    Methods: To generate PROM items, 15 patients with chronic constipation (age range =28-79 years, 10 females) underwent a qualitative interview exploring their experiences with chronic constipation. Following that, eight clinical experts completed the content validity index (CVI) ratings of all the items generated to assess content validity. Based on results of the content validity assessment, relevant items were maintained and 12 participants with chronic constipation were re-interviewed to obtain feedback about comprehensibility, comprehensiveness and relevance.
    Results: Six themes and 25 sub-themes emerged from the qualitative interview, and an initial list of 33 symptom items and 18 quality of life (QoL) items were generated. Based on the CVIs calculated, 11 symptom items and nine QoL items were maintained with the scale-content validity index indicating excellent content validity. Overall, participants indicated the PROM to be relevant, comprehensive and easy to understand however, minor amendments were made to improve the three qualities of interest.
    Conclusion: The current study developed a constipation PROM that measures both symptom severity and constipation-related QoL, with supporting evidence for relevance, comprehensiveness and comprehensibility. Further prioritization should be given to validating and exploring new digital modalities of PROM administration.
    Language English
    Publishing date 2023-09-29
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2694435-2
    ISSN 2001-0370
    ISSN 2001-0370
    DOI 10.1016/j.csbj.2023.09.034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Chemical structures, extraction and analysis technologies, and bioactivities of edible fungal polysaccharides from Poria cocos: An updated review.

    Ng, Chester Yan Jie / Lai, Nicole Poh Yee / Ng, Wen Min / Siah, Kewin Tien Ho / Gan, Ren-You / Zhong, Linda L D

    International journal of biological macromolecules

    2024  Volume 261, Issue Pt 1, Page(s) 129555

    Abstract: Poria cocos is a popular medicinal food. Polysaccharides are the key component of Poria cocos, forming 70-90 % of the dry sclerotia mass. Recent studies indicate that Poria cocos polysaccharides (PCP-Cs) have multiple beneficial functions and ... ...

    Abstract Poria cocos is a popular medicinal food. Polysaccharides are the key component of Poria cocos, forming 70-90 % of the dry sclerotia mass. Recent studies indicate that Poria cocos polysaccharides (PCP-Cs) have multiple beneficial functions and applications. A literature search was conducted using the Web of Science Core Collection and PubMed databases. For this review, we provided an updated research progress in chemical structures, various extraction and analysis technologies, bioactivities of PCP-Cs, and insights into the directions for future research. The main polysaccharides identified in Poria cocos are water-soluble polysaccharides and acidic polysaccharides. Hot water, alkali, supercritical fluid, ultrasonic, enzyme, and deep eutectic solvent-based methods are the most common methods for PCP-Cs extraction. Technologies such as near-infrared spectroscopy, high-performance liquid chromatography, and ultraviolet-visible spectrophotometry, are commonly used to evaluate the qualities of PCP-Cs. In addition, PCP-Cs have antioxidant, immunomodulatory, neuroregulatory, anticancer, hepatoprotective, and gut microbiota regulatory properties. Future research is needed to focus on scaling up extraction, enhancing quality control, elucidating mechanisms of bioactivities, and the utilisation of PCP-Cs in food industries. Overall, Poria cocos is a good source of edible fungi polysaccharides, which can be developed into functional foods with potential health benefits.
    MeSH term(s) Fungal Polysaccharides/pharmacology ; Fungal Polysaccharides/chemistry ; Wolfiporia/chemistry ; Polysaccharides/pharmacology ; Polysaccharides/chemistry ; Water ; Quality Control ; Poria/chemistry
    Chemical Substances Fungal Polysaccharides ; Polysaccharides ; Water (059QF0KO0R)
    Language English
    Publishing date 2024-01-25
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2024.129555
    Database MEDical Literature Analysis and Retrieval System OnLINE

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